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Creation of optically-functional titanium surface with compatibility of bone forming ability and antibacterial activity and its application to implants

Research Project

Project/Area Number 18H01718
Research Category

Grant-in-Aid for Scientific Research (B)

Allocation TypeSingle-year Grants
Section一般
Review Section Basic Section 26030:Composite materials and interfaces-related
Research InstitutionTohoku University

Principal Investigator

Narushima Takayuki  東北大学, 工学研究科, 教授 (20198394)

Co-Investigator(Kenkyū-buntansha) 佐原 亮二  国立研究開発法人物質・材料研究機構, 構造材料研究拠点, グループリーダー (30323075)
小笠原 康悦  東北大学, 加齢医学研究所, 教授 (30323603)
上田 恭介  東北大学, 工学研究科, 准教授 (40507901)
金高 弘恭  東北大学, 歯学研究科, 教授 (50292222)
Project Period (FY) 2018-04-01 – 2022-03-31
Project Status Completed (Fiscal Year 2021)
Budget Amount *help
¥17,290,000 (Direct Cost: ¥13,300,000、Indirect Cost: ¥3,990,000)
Fiscal Year 2021: ¥2,210,000 (Direct Cost: ¥1,700,000、Indirect Cost: ¥510,000)
Fiscal Year 2020: ¥4,940,000 (Direct Cost: ¥3,800,000、Indirect Cost: ¥1,140,000)
Fiscal Year 2019: ¥4,030,000 (Direct Cost: ¥3,100,000、Indirect Cost: ¥930,000)
Fiscal Year 2018: ¥6,110,000 (Direct Cost: ¥4,700,000、Indirect Cost: ¥1,410,000)
Keywords生体材料 / チタン / 抗菌性 / 光機能 / 骨形成能 / 酸化チタン / 表面処理 / 酸化 / アナターゼ
Outline of Final Research Achievements

We succeeded in fabricating a Ti surface with both osteogenic and antibacterial properties for application to dental implants. The Au-containing TiO2 layers prepared on the Ti surface by an original process based on Au-sputtering and thermal oxidation showed antibacterial activity against E. coli under visible-light irradiation.
The photofunction of the Au-containing TiO2 layers obtained in this study is considered to be an achievement to realize the “self-maintenance function” in which the implant itself plays a role in “healing” by reattaching to bone tissue and also enables “prevention” by patients themselves.
These results, together with the excellent adhesion between the TiO2 layers and the Ti substrates, are expected to be applied not only to dental implants but also to the prevention of contact infection of the new coronavirus (SARS-CoV-2).

Academic Significance and Societal Importance of the Research Achievements

学術的意義:可視光照射により抗菌活性値1以上を示し、かつ優れた密着力を有するTiO2膜をインプラント用チタン表面に作製するプロセスを構築した。光照射がない場合にはTiO2の優れた骨形成能が保持されることも示され、骨形成能・抗菌能・密着力を共立させたチタン表面の設計のための学術的基盤を構築することができた。
社会的意義:歯科において14%という高確率で発症するインプラント周囲炎に対して、「セルフメインテナンス機能」具現化への成果と考えられる。これらは輸入品が90%を占める歯科インプラント市場における日本発の技術となり得るものである。

Report

(4 results)
  • 2021 Final Research Report ( PDF )
  • 2020 Annual Research Report
  • 2019 Annual Research Report
  • 2018 Annual Research Report
  • Research Products

    (67 results)

All 2021 2020 2019 2018 Other

All Int'l Joint Research (1 results) Journal Article (23 results) (of which Int'l Joint Research: 1 results,  Peer Reviewed: 20 results,  Open Access: 1 results) Presentation (40 results) (of which Int'l Joint Research: 15 results,  Invited: 11 results) Book (3 results)

  • [Int'l Joint Research] University of Minho(ポルトガル)

    • Related Report
      2018 Annual Research Report
  • [Journal Article] Formation of carbon-added anatase-rich TiO2 layers on titanium and their antibacterial properties in visible light2021

    • Author(s)
      Ueda Takatoshi、Sato Naoki、Koizumi Ryusuke、Ueda Kyosuke、Ito Koyu、Ogasawara Kouetsu、Narushima Takayuki
    • Journal Title

      Dental Materials

      Volume: 37 Issue: 2 Pages: e37-e46

    • DOI

      10.1016/j.dental.2020.10.009

    • Related Report
      2020 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Antibacterial Functionalization of Ti-based Biomaterials Based on the Understanding of the Inactivation Mechanisms of Bacteria via Photocatalytic Activity of Titanium Oxide: Visible-light Responsive Reaction of Titanium Oxide Coating2020

    • Author(s)
      Ueda Kyosuke、Ueda Takatoshi、Narushima Takayuki
    • Journal Title

      Materia Japan

      Volume: 59 Issue: 11 Pages: 612-617

    • DOI

      10.2320/materia.59.612

    • NAID

      130007933504

    • ISSN
      1340-2625, 1884-5843
    • Year and Date
      2020-11-01
    • Related Report
      2020 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Using HAADF-STEM for atomic-scale evaluation of incorporation of antibacterial Ag atoms in a β-tricalcium phosphate structure2020

    • Author(s)
      Gokcekaya Ozkan、Ueda Kyosuke、Narushima Takayuki、Nakano Takayoshi
    • Journal Title

      Nanoscale

      Volume: 12 Issue: 31 Pages: 16596-16604

    • DOI

      10.1039/d0nr04208k

    • Related Report
      2020 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Predicting the Parabolic Rate Constants of High-Temperature Oxidation of Ti Alloys Using Machine Learning2020

    • Author(s)
      Bhattacharya Somesh Kr.、Sahara Ryoji、Narushima Takayuki
    • Journal Title

      Oxidation of Metals

      Volume: 94 Issue: 3-4 Pages: 205-218

    • DOI

      10.1007/s11085-020-09986-3

    • Related Report
      2020 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Crystallographic orientation control of pure chromium via laser powder bed fusion and improved high temperature oxidation resistance2020

    • Author(s)
      Gokcekaya Ozkan、Hayashi Naohiro、Ishimoto Takuya、Ueda Kyosuke、Narushima Takayuki、Nakano Takayoshi
    • Journal Title

      Additive Manufacturing

      Volume: 36 Pages: 101624-101624

    • DOI

      10.1016/j.addma.2020.101624

    • Related Report
      2020 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Fabrication and bioresorbability of Ag- and Ta-containing amorphous calcium phosphate films formed on titanium substrates by RF magnetron sputtering2020

    • Author(s)
      Wu Jun、Ueda Kyosuke、Narushima Takayuki
    • Journal Title

      MATEC Web of Conferences

      Volume: 321 Pages: 05007-05007

    • DOI

      10.1051/matecconf/202032105007

    • Related Report
      2020 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Recent activities of titanium research and development in Japan2020

    • Author(s)
      Narushima Takayuki、Sugizaki Yasuaki
    • Journal Title

      MATEC Web of Conferences

      Volume: 321 Pages: 01004-01004

    • DOI

      10.1051/matecconf/202032101004

    • Related Report
      2020 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Si添加Ti-6Al-4V合金の高温酸化に関する実験的・計算材料学的研究2020

    • Author(s)
      成島尚之, 上田恭介, 佐原亮二, S.K. Bhattacharya
    • Journal Title

      チタン

      Volume: 68 Pages: 328-335

    • NAID

      40022392470

    • Related Report
      2020 Annual Research Report
  • [Journal Article] 非晶質リン酸カルシウムの生体内溶解性制御とAg担体として利用したチタンへの抗菌性付与2020

    • Author(s)
      上田恭介, 成島尚之
    • Journal Title

      バイオマテリアルー生体材料

      Volume: 38 Pages: 242-247

    • Related Report
      2020 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Fabrication of Ag and Ta co-doped amorphous calcium phosphate coating films by radiofrequency magnetron sputtering and their antibacterial activity2020

    • Author(s)
      J. Wu, K. Ueda and T. Narushima
    • Journal Title

      Mater. Sci. Eng. C

      Volume: 109 Pages: 110599-110599

    • DOI

      10.1016/j.msec.2019.110599

    • Related Report
      2019 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Mechanisms of oxidation of pure and Si-segregated α-Ti surfaces2020

    • Author(s)
      S.Kr. Bhattacharya, R. Sahara, K. Ueda and T. Narushima
    • Journal Title

      Proceedings of the 14th World Conference on Titanium (Ti-2019)

      Volume: -

    • Related Report
      2019 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Fabrication and bioresorbability of Ag- and Ta-containing amorphous calcium phosphate films formed on titanium substrates by RF magnetron sputtering2020

    • Author(s)
      J. Wu, K. Ueda and T. Narushima
    • Journal Title

      Proceedings of the 14th World Conference on Titanium (Ti-2019)

      Volume: -

    • Related Report
      2019 Annual Research Report
    • Peer Reviewed
  • [Journal Article] 熱酸化により作製したチタニアコーティング膜の可視光応答光触媒活性による抗菌機能化2020

    • Author(s)
      上田恭介, 上田隆統志, 成島尚之
    • Journal Title

      セラミックス

      Volume: 55 Pages: 146-149

    • Related Report
      2019 Annual Research Report
    • Peer Reviewed
  • [Journal Article] 金属の表面処理で生体用素材を多機能化2020

    • Author(s)
      成島尚之
    • Journal Title

      現代化学

      Volume: 587 Pages: 50-53

    • Related Report
      2019 Annual Research Report
  • [Journal Article] Formation of Photocatalytically Active TiO<sub>2</sub> Layers on Ti–Nb Alloys by Two-Step Thermal Oxidation2019

    • Author(s)
      S. Sado, T. Ueda, Y. Tokuda, N. Sato, K. Ueda and T. Narushima
    • Journal Title

      MATERIALS TRANSACTIONS

      Volume: 60 Issue: 9 Pages: 1814-1820

    • DOI

      10.2320/matertrans.ME201901

    • NAID

      130007695362

    • ISSN
      1345-9678, 1347-5320
    • Year and Date
      2019-07-01
    • Related Report
      2019 Annual Research Report 2018 Annual Research Report
    • Peer Reviewed
  • [Journal Article] COX-2 induces T cell accumulation and IFN-γ production during the development of chromium allergy2019

    • Author(s)
      Sitalaksmi Ratri Maya、Ito Koyu、Ogasawara Kouetsu、Suto Yoshiko、Itabashi Madoka、Ueda Kyosuke、Hirasawa Noriyasu、Narushima Takayuki、Hendrijantini Nike、Kresnoadi Utari、Sasaki Keiichi
    • Journal Title

      Autoimmunity

      Volume: 52 Issue: 5-6 Pages: 228-234

    • DOI

      10.1080/08916934.2019.1662404

    • Related Report
      2019 Annual Research Report
    • Peer Reviewed / Int'l Joint Research
  • [Journal Article] 金属系バイオマテリアルの表面処理2019

    • Author(s)
      成島尚之
    • Journal Title

      特殊鋼

      Volume: 68 Pages: 45-48

    • Related Report
      2019 Annual Research Report
  • [Journal Article] Visible‐light‐responsive antibacterial activity of Au‐incorporated TiO 2 layers formed on Ti?(0?10)at%Au alloys by air oxidation2019

    • Author(s)
      Ueda Takatoshi、Ueda Kyosuke、Ito Koyu、Ogasawara Kouetsu、Kanetaka Hiroyasu、Mokudai Takayuki、Niwano Yoshimi、Narushima Takayuki
    • Journal Title

      Journal of Biomedical Materials Research Part A

      Volume: 107 Issue: 5 Pages: 991-1000

    • DOI

      10.1002/jbm.a.36624

    • Related Report
      2018 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Antibacterial activity of Ag nanoparticle-containing hydroxyapatite powders in simulated body fluids with Cl ions2019

    • Author(s)
      O. Gokcekaya, K. Ueda, K. Ogasawara and T. Narushima
    • Journal Title

      Mater. Chem. Phys.

      Volume: 223 Pages: 473-478

    • Related Report
      2018 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Experimental and theoretical study of the effect of Si addition on oxidation behavior of Ti-6Al-4V alloys2019

    • Author(s)
      K. Maeda, S. Suzuki, K. Ueda, T. Kitashima, Somesh Kr. Bhattacharya, R. Sahara and T. Narushima
    • Journal Title

      J. Alloys Compd.

      Volume: 776 Pages: 519-528

    • DOI

      10.1016/j.jallcom.2018.10.291

    • Related Report
      2018 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Mechanism of oxidation of pure and Si-segregated α-Ti surfaces2019

    • Author(s)
      S.K. Bhattacharya, R. Sahara, S. Suzuki, K. Ueda and T. Narushima
    • Journal Title

      Appl. Surf. Sci.

      Volume: 463 Pages: 686-692

    • DOI

      10.1016/j.apsusc.2018.08.253

    • Related Report
      2018 Annual Research Report
    • Peer Reviewed
  • [Journal Article] チタンの高温酸化2018

    • Author(s)
      成島尚之
    • Journal Title

      軽金属

      Volume: 68 Pages: 354-365

    • Related Report
      2018 Annual Research Report
    • Peer Reviewed
  • [Journal Article] チタンへの骨適合性コーティング2018

    • Author(s)
      上田恭介,上田隆統志,佐藤直生,成島尚之
    • Journal Title

      表面技術

      Volume: 69 Pages: 341-345

    • NAID

      130007586417

    • Related Report
      2018 Annual Research Report
    • Peer Reviewed
  • [Presentation] Antibacterial activity of Ag-Ta co-containing amorphous calcium phosphate coating films2020

    • Author(s)
      K. Ueda, J. Wu, K. Ito, K. Ogasawara, H. Kanetaka, T. Narushima
    • Organizer
      11th World Biomaterials Congress
    • Related Report
      2020 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Effect of Ta addition on the antibacterial activity and cytotoxicity of Ag-containing amorphous calcium phosphate coating film2020

    • Author(s)
      K. Ueda, J. Wu, K. Ito, K. Ogasawara, M. Furuya, K. Yokota, H. Kanetaka, T. Narushima
    • Organizer
      International Joint Symposium 2020, The 15th International Workshop on Biomaterials in Interface Science, The 11th Symposium on Innovative Dental-Engineering Alliance (IDEA)
    • Related Report
      2020 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Visible-light-induced antibacterial activity of TiO2 layer formed by the two-step thermal oxidation2020

    • Author(s)
      R. Koizumi, K. Ueda, K. Ito, K. Ogasawara, T. Narushima
    • Organizer
      The 4th Symposium for The Core Research Cluster for Materials Science
    • Related Report
      2020 Annual Research Report
    • Int'l Joint Research
  • [Presentation] 金属系バイオマテリアルの表面・組織制御2020

    • Author(s)
      成島尚之
    • Organizer
      東北大学材料科学ウェビナー, セッションB
    • Related Report
      2020 Annual Research Report
  • [Presentation] チタン表面に作製した炭素・窒素含有TiO2膜の可視光照射下における抗菌能2020

    • Author(s)
      古泉隆祐、上田隆統志、上田恭介、伊藤甲雄、小笠原康悦、成島尚之
    • Organizer
      日本金属学会第167回大会(2020年秋期)
    • Related Report
      2020 Annual Research Report
  • [Presentation] 2段階熱酸化法による窒素添加酸化チタン膜の作製とその抗菌性評価2020

    • Author(s)
      上田恭介、上田隆統志、佐藤直生、古泉隆祐、目代貴之、伊藤甲雄、小笠原康悦、金髙弘恭、成島尚之
    • Organizer
      学際・国際的人材養成ライフイノベーションマテリアル創製共同研究プロジェクト 第5回公開討論会
    • Related Report
      2020 Annual Research Report
  • [Presentation] Evaluation of long-term antibacterial activity of Ag-containing amorphous calcium phosphate films with various Ta contents2020

    • Author(s)
      Jun Wu, 上田恭介、伊藤甲雄、小笠原康悦、金髙弘恭、成島尚之
    • Organizer
      第3回 日本金属学会第7分野講演会「金属系バイオマテリアルサイエンスの新展開(III)」
    • Related Report
      2020 Annual Research Report
  • [Presentation] Ag, Ta共添加非晶質リン酸カルシウム膜からのAgイオン放出制御と抗菌性2020

    • Author(s)
      上田恭介、Wu Jun、伊藤甲雄、小笠原康悦、古谷真衣子、金髙弘恭、成島尚之
    • Organizer
      日本金属学会第168回大会(2021年春期)
    • Related Report
      2020 Annual Research Report
  • [Presentation] 二段階熱酸化により作製した窒素含有TiO2膜の可視光照射誘起抗菌性および細胞毒性評価2020

    • Author(s)
      古泉隆祐、島田啓太、上田恭介、伊藤甲雄、小笠原康悦、古谷真衣子、金髙弘恭、成島尚之
    • Organizer
      日本金属学会第168回大会(2021年春期)
    • Related Report
      2020 Annual Research Report
  • [Presentation] 実用歯科用チタン・チタン合金表面に作製した炭素・窒素含有TiO2膜の可視光応答型光触媒活性2020

    • Author(s)
      古泉隆佑、佐藤直生、上田隆統志、上田恭介、伊藤甲雄、小笠原康悦、成島尚之
    • Organizer
      日本金属学会第166回大会(2020年春期)
    • Related Report
      2019 Annual Research Report
  • [Presentation] Preparation of bioceramic coatings on Ti and its alloys by dry processes and their antibacterial activity2019

    • Author(s)
      T. Narushima
    • Organizer
      The 10th Pacific Rim International Conference on Advance Materials and Processing (PRICM-10)
    • Related Report
      2019 Annual Research Report
    • Int'l Joint Research / Invited
  • [Presentation] 金属チタン研究の最先端2019

    • Author(s)
      成島尚之
    • Organizer
      日本機械学会2019年度年次大会
    • Related Report
      2019 Annual Research Report
    • Invited
  • [Presentation] 日本チタン研究の最先端2019

    • Author(s)
      成島尚之
    • Organizer
      一般社団法人日本チタン協会, 2019年度通常総会記念講演会
    • Related Report
      2019 Annual Research Report
    • Invited
  • [Presentation] Formation of carbon/nitrogen-added TiO2 layers on Ti via two-step thermal oxidation and their visible-light photocatalytic activity2019

    • Author(s)
      R. Koizumi, N. Sato, T. Ueda, K. Ueda, K. Ito, K. Ogasawara and T. Narushima
    • Organizer
      The 4th International Symposium on Creation of Life Innovation Materials for Interdisciplinary and International Researcher Development (iLIM-4)
    • Related Report
      2019 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Fabrication and bioresorbability of Ag- and Ta-containing amorphous calcium phosphate films formed on titanium substrates by RF magnetron sputtering2019

    • Author(s)
      J. Wu, K. Ueda and T. Narushima
    • Organizer
      The 14th World Conference on Titanium
    • Related Report
      2019 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Mechanisms of oxidation of pure and Si-segregated α-Ti surfaces2019

    • Author(s)
      S.K. Bhattacharya, R. Sahara, K. Ueda and T. Narushima
    • Organizer
      The 14th World Conference on Titanium (Ti-2019)
    • Related Report
      2019 Annual Research Report
    • Int'l Joint Research
  • [Presentation] 実用歯科用チタン合金表面に作製した炭素・窒素含有TiO2膜の可視光応答性評価2019

    • Author(s)
      古泉隆佑、佐藤直生、上田隆統志、上田恭介、伊藤甲雄、小笠原康悦、成島尚之
    • Organizer
      第2回日本金属学会第7分野講演会「金属系バイオマテリアルサイエンスの新展開(II)」
    • Related Report
      2019 Annual Research Report
  • [Presentation] 二段階熱酸化によるチタンへの炭素・窒素含有TiO2膜の作製と可視光応答型光触媒活性2019

    • Author(s)
      古泉隆佑、佐藤直生、上田隆統志、上田恭介、伊藤甲雄、小笠原康悦、成島尚之
    • Organizer
      東北大学金属材料研究所共同研究ワークショップ・日本バイオマテリアル学会東北ブロック講演会「バイオマテリアル研究を牽引する研究者との対話」
    • Related Report
      2019 Annual Research Report
  • [Presentation] Ti-Au合金表面に作製したAu添加TiO2膜の可視光照射下における抗菌能2019

    • Author(s)
      上田隆統志、上田恭介、伊藤甲雄、小笠原康悦、金高弘恭、目代貴之、庭野吉己、成島尚之
    • Organizer
      日本防菌防黴学会 第46回年次大会
    • Related Report
      2019 Annual Research Report
  • [Presentation] Evaluation of antibacterial activity of Ag- and Ta-containing amorphous calcium phosphate films2019

    • Author(s)
      J. Wu, K. Ueda, K. Ito, K. Ogasawara and T. Narushima
    • Organizer
      日本金属学会第165回大会(2019年秋期)
    • Related Report
      2019 Annual Research Report
  • [Presentation] 骨形成能向上を目的としたリン酸カルシウムコーティングとその展望2019

    • Author(s)
      上田恭介、成島尚之
    • Organizer
      第39回日本骨形態計測学会
    • Related Report
      2019 Annual Research Report
    • Invited
  • [Presentation] Au蒸着Ti基板の大気参加によるAu添加TiO2膜の作製およびその可視光誘起抗菌能2019

    • Author(s)
      上田隆統志, 佐藤直生, 上田恭介, 伊藤甲雄, 小笠原康悦, 目代貴之, 金髙弘恭, 成島尚之
    • Organizer
      日本金属学会第164回大会(2019年春期)
    • Related Report
      2018 Annual Research Report
  • [Presentation] Dissolution behavior of Ag- and Ta-containing amorphous calcium phosphate films in simulated body fluids2019

    • Author(s)
      J. Wu, K. Ueda and T. Narushima
    • Organizer
      日本金属学会第164回大会(2019年春期)
    • Related Report
      2018 Annual Research Report
  • [Presentation] Antibacterial activity of TiO2 layers formed on Ti-Au alloys by thermal oxidation2018

    • Author(s)
      T. Narushima, T. Ueda, N. Sato, K. Ueda, K. Ito, K. Ogasawara and H. Kanetaka
    • Organizer
      Finland-Japan Workshop: The next generation medical engineering in biomaterials, Joint with 3rd Bone and Biomaterials Workshop
    • Related Report
      2018 Annual Research Report
    • Int'l Joint Research / Invited
  • [Presentation] Formation and antibacterial activity of TiO2 layers on Ti-Au alloys2018

    • Author(s)
      T. Narushima, K. Ueda, T. Ueda and N. Sato
    • Organizer
      15th International Symposium on Functionally Graded Materials, (ISFGMs2018)
    • Related Report
      2018 Annual Research Report
    • Int'l Joint Research / Invited
  • [Presentation] Visible-light-driven antibacterial properties of Au-added TiO2 layers formed by thermal oxidation2018

    • Author(s)
      T. Ueda, N. Sato, K. Ueda, K. Ito, K. Ogasawara, T. Mokudai, H. Kanetaka and T. Narushima
    • Organizer
      The 3rd International Symposium on Creation of Life Innovation Materials for Interdisciplinary and International Researcher Development (iLIM-3)
    • Related Report
      2018 Annual Research Report
    • Int'l Joint Research / Invited
  • [Presentation] Bio-functionalization of amorphous calcium phosphate films by element addition2018

    • Author(s)
      K. Ueda, J. Wu, K. Ito, K. Ogasawara and T. Narushima
    • Organizer
      The 3rd International Symposium on Creation of Life Innovation Materials for Interdisciplinary and International Researcher Development (iLIM-3)
    • Related Report
      2018 Annual Research Report
    • Int'l Joint Research / Invited
  • [Presentation] RFマグネトロンスパッタリング法による元素添加生体内溶解性非晶質リン酸カルシウム膜の作製とその評価2018

    • Author(s)
      上田恭介, J. Wu, 成島尚之, 小笠原康悦
    • Organizer
      スパッタリングおよびプラズマプロセス研究部会(SP部会)、第160回定例研究会
    • Related Report
      2018 Annual Research Report
    • Invited
  • [Presentation] Mechanisms of oxidation of pure and Si-segregated α-Ti surface2018

    • Author(s)
      R. Sahara, S. K. Bhattacharya, S. Suzuki, K. Ueda and T. Narushima
    • Organizer
      International Workshop on Evolution of Electronic Structure Theory & Experimental Realization (EESTER-2018)
    • Related Report
      2018 Annual Research Report
    • Int'l Joint Research / Invited
  • [Presentation] Design of High Temperature Materials by First Principles Based Thermodynamic Calculations2018

    • Author(s)
      R. Sahara, S. K. Bhattacharya, K. Ueda, T. Narushima, T. Osada, S. Bhattacharyya and K. Ohno
    • Organizer
      16th Discussion Meeting on Thermodynamics of Alloys (TOFA2018)
    • Related Report
      2018 Annual Research Report
    • Int'l Joint Research / Invited
  • [Presentation] Fabrication and bioresorbability of Ag-containing amorphous calcium phosphate films with various Ta contents2018

    • Author(s)
      J. Wu, K. Ueda, K. Ito, K. Ogasawara and T. Narushima
    • Organizer
      2018 13th International Workshop on Biomaterials in Interface Science
    • Related Report
      2018 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Mechanisms of Oxidation of Pure and Si-segregated α-Ti Surfaces2018

    • Author(s)
      S. K. Bhattacharya, R. Sahara, K. Ueda and T. Narushima
    • Organizer
      TMS2019 148th Annual Meeting & Exhibition
    • Related Report
      2018 Annual Research Report
    • Int'l Joint Research
  • [Presentation] 二段階熱酸化による歯科用Ti合金上へのTiO2膜作製と抗菌性評価2018

    • Author(s)
      佐藤直生, 上田隆統志, 上田恭介, 伊藤甲雄, 笠原康悦, 成島尚之
    • Organizer
      東北大学金属材料研究所共同研究ワークショップ・日本バイオマテリアル学会東北ブロック講演会
    • Related Report
      2018 Annual Research Report
  • [Presentation] Fabrication of Ag and Ta-containing amorphous calcium phosphate films by RF magnetron sputtering and their bioresorbability2018

    • Author(s)
      J. Wu, K. Ueda, K. Ito, K. Ogasawara and T. Narushima
    • Organizer
      東北大学金属材料研究所共同研究ワークショップ・日本バイオマテリアル学会東北ブロック講演会
    • Related Report
      2018 Annual Research Report
  • [Presentation] 二段階熱酸化により実用Ti合金上に作製したTiO2膜の性状と処理条件の関係2018

    • Author(s)
      佐藤直生, 上田隆統志, 上田恭介, 伊藤甲雄, 小笠原康悦, 成島尚之
    • Organizer
      日本金属学会第163回大会(2018年秋期)
    • Related Report
      2018 Annual Research Report
  • [Presentation] Noble metal containing TiO2 layers formed by air oxidation and their photocatalytic activity under visible-light irradiation2018

    • Author(s)
      H. Meng, T. Ueda, N. Sato, K. Ueda and T. Narushima
    • Organizer
      日本金属学会第163回大会(2018年秋期)
    • Related Report
      2018 Annual Research Report
  • [Presentation] Fabrication of Ag containing amorphous calcium phosphate films with various Ta contentns by RF magnetron sputtering and their bioresorbability2018

    • Author(s)
      J. Wu, K. Ueda, K. Ito, K. Ogasawara and T. Narushima
    • Organizer
      日本金属学会第163回大会(2018年秋期)
    • Related Report
      2018 Annual Research Report
  • [Presentation] 熱酸化法を用いた歯科用チタン合金の抗菌化表面処理2018

    • Author(s)
      佐藤直生, 上田隆統志, 上田恭介, 成島尚之, 伊藤甲雄, 小笠原康悦
    • Organizer
      軽金属学会第135回秋期大会
    • Related Report
      2018 Annual Research Report
  • [Presentation] Ta, Ag含有非晶質リン酸カルシウム薄膜の作製と擬似体液中における溶解挙動2018

    • Author(s)
      上田恭介, J. Wu, 成島尚之
    • Organizer
      第40回日本バイオマテリアル学会大会
    • Related Report
      2018 Annual Research Report
  • [Presentation] 二段階熱酸化法による歯科用チタン合金への可視光応答型抗菌化表面処理2018

    • Author(s)
      上田恭介, 佐藤直生, 上田隆統志, 成島尚之, 伊藤甲雄, 小笠原康悦, 目代貴之
    • Organizer
      学際・国際的人材養成ライフイノベーションマテリアル創製共同研究プロジェクト 生体医療・福祉材料分野 平成30年度分科会(全体会議)
    • Related Report
      2018 Annual Research Report
  • [Book] チタンの準安定相・析出相研究部会報告書2020

    • Author(s)
      1.成島尚之, 上田恭介, 廣瀬祐介
    • Total Pages
      139
    • Publisher
      軽金属学会
    • ISBN
      9784909160324
    • Related Report
      2020 Annual Research Report
  • [Book] 有機/無機材料の表面処理・改質による生体適合性付与2019

    • Author(s)
      上田恭介、佐藤直生、成島尚之
    • Total Pages
      315
    • Publisher
      シーエムシー出版
    • ISBN
      9784781314150
    • Related Report
      2019 Annual Research Report
  • [Book] Metals for biomedical devices, Second Edition2019

    • Author(s)
      T. Narushima
    • Total Pages
      596
    • Publisher
      Woodhead Publishing
    • ISBN
      9780081026663
    • Related Report
      2019 Annual Research Report

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Published: 2018-04-23   Modified: 2023-01-30  

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