Systematic mutational analysis of a relationship between a protein's immunogenicity and aggregation tendency using Solubility Conttroling Peptide (SCP) tags

• Project/Area Number: 18H02385
• Research Category: Grant-in-Aid for Scientific Research (B)
• Allocation Type: Single-year Grants
• Section: 一般
• Review Section: Basic Section 43020:Structural biochemistry-related
• Research Institution: Tokyo University of Agriculture and Technology
• Principal Investigator: 黒田 裕 東京農工大学, 工学(系)研究科(研究院), 教授 (10312240)
• Project Period (FY): 2018-04-01 – 2022-03-31
• Project Status: Granted (Fiscal Year 2020)
• Budget Amount: ¥17,810,000 (Direct Cost: ¥13,700,000、Indirect Cost: ¥4,110,000); Fiscal Year 2020: ¥3,380,000 (Direct Cost: ¥2,600,000、Indirect Cost: ¥780,000); Fiscal Year 2019: ¥3,120,000 (Direct Cost: ¥2,400,000、Indirect Cost: ¥720,000); Fiscal Year 2018: ¥10,010,000 (Direct Cost: ¥7,700,000、Indirect Cost: ¥2,310,000)
• Keywords: 生物物理 / タンパク質 / バイオテクノロジー / 免疫原性 / 会合性の制御