Integration of nutrient and microbial cues in the regulation of plant immunity
| Project/Area Number |
18H02467
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| Research Category |
Grant-in-Aid for Scientific Research (B)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Review Section |
Basic Section 44030:Plant molecular biology and physiology-related
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| Research Institution | Nara Institute of Science and Technology |
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Principal Investigator |
Saijo Yusuke 奈良先端科学技術大学院大学, 先端科学技術研究科, 教授 (50587764)
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| Project Period (FY) |
2018-04-01 – 2021-03-31
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| Project Status |
Completed (Fiscal Year 2020)
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| Budget Amount *help |
¥17,160,000 (Direct Cost: ¥13,200,000、Indirect Cost: ¥3,960,000)
Fiscal Year 2020: ¥6,240,000 (Direct Cost: ¥4,800,000、Indirect Cost: ¥1,440,000)
Fiscal Year 2019: ¥6,240,000 (Direct Cost: ¥4,800,000、Indirect Cost: ¥1,440,000)
Fiscal Year 2018: ¥4,680,000 (Direct Cost: ¥3,600,000、Indirect Cost: ¥1,080,000)
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| Keywords | 植物微生物相互作用 / 植物免疫 / 共生 / 環境応答 / 土壌栄養 / 貧栄養 / マイクロバイオーム / リン / PSR / 微生物 / シグナル伝達 / 受容体 / 栄養 / 環境適応 |
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| Outline of Final Research Achievements |
This project aims at a better understanding of the mechanisms by which plants integrate microbial and nutritional cues to finetune their immune responses to pathogenic and mutualistic microbes. We show that damage-inducible Pep peptides provides a pathogen-specific defense pathway, which is sensitized under phosphate deficiency in which plants typically rely on mutualistic microbes for nutrition. Our investigation into the molecular links between immune and phosphate starvation response (PSR) pathways reveals a key role played by PMR4 callose synthase in root callose deposition and phosphate acquisition during PSR. Conversely, our genetic studies on PSR pathways via PHR1/PHL1 transcription factors and LPR1/LPR2 ferroxydases further show their critical role in the control of root-associated microbiomes even under nutrient sufficiency. These findings shed new light on a previously unsuspected, intimate linkage between plant immunity and nutrition deficiency responses.
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| Academic Significance and Societal Importance of the Research Achievements |
植物と微生物の関係性は環境に応じて大きく変わるものの、その実態や制御機構の解明は遅れている。共生菌に依存する低リン条件で病原菌の防除に働くPepペプチドシグナル系の解明は、栄養情報にもとづき植物が免疫・共生制御を行う仕組みの一端を明らかにしており、国内外で求められている植物微生物環境の三者相互作用研究に先鞭をつけるものである。また、野外環境で実効性の高い病害抵抗性作物や共生菌制御技術の開発に向けても有意義な知見を提供している。本成果は、環境変動に耐える頑強な作物の作出や効率的な共生菌・土壌栄養利用を可能にし、持続可能な食料生産システムの構築に貢献するものである。
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Report
(3 results)
Research Products
(20 results)
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[Journal Article] Pattern recognition receptors confer plant salt tolerance via WRKY18/WRKY40 transcription factors2020
Author(s)
Eliza P. Loo, Yuri Tajima, Kohji Yamada, Taishi Hirase, Hirotaka Ariga, Tadashi Fujiwara, Keisuke Tanaka, Teruaki Taji, Imre E. Somssich, Jane E. Parker, Yusuke Saijo
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Journal Title
DOI
Related Report
Open Access / Int'l Joint Research
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[Journal Article] Identifying the target genes of SUPPRESSOR OF GAMMA RESPONSE 1, a master transcription factor controlling DNA damage response in Arabidopsis.2018
Author(s)
Ogita N, Okushima Y, Tokizawa M, Yamamoto YY, Tanaka M, Seki M, Makita Y, Matsui M, Okamoto-Yoshiyama K, Sakamoto T, Kurata T, Hiruma K, Saijo Y, Takahashi N, Umeda M.
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Journal Title
The Plant Journal
Volume: -
Pages: 439-453
DOI
NAID
Related Report
Peer Reviewed / Open Access
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