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Deciphering the Evolutionary Reduction of Skull Bones from Suture Closure

Research Project

Project/Area Number 18H02492
Research Category

Grant-in-Aid for Scientific Research (B)

Allocation TypeSingle-year Grants
Section一般
Review Section Basic Section 45030:Biodiversity and systematics-related
Research InstitutionUniversity of Tsukuba (2020, 2022)
Tokyo Medical and Dental University (2019)
Musashino Art University (2018)

Principal Investigator

Koyabu Daisuke  筑波大学, プレシジョン・メディスン開発研究センター, 准教授 (60712510)

Project Period (FY) 2018-04-01 – 2021-03-31
Project Status Completed (Fiscal Year 2022)
Budget Amount *help
¥17,290,000 (Direct Cost: ¥13,300,000、Indirect Cost: ¥3,990,000)
Fiscal Year 2020: ¥2,860,000 (Direct Cost: ¥2,200,000、Indirect Cost: ¥660,000)
Fiscal Year 2019: ¥5,590,000 (Direct Cost: ¥4,300,000、Indirect Cost: ¥1,290,000)
Fiscal Year 2018: ¥8,840,000 (Direct Cost: ¥6,800,000、Indirect Cost: ¥2,040,000)
Keywords進化 / 進化発生学 / 比較解剖学 / 頭蓋 / 形態学
Outline of Final Research Achievements

The aim of this study was to determine how the crania of amniotes, which consist of birds, reptiles and mammals, are homologous between the various phylogenetic groups. Our previous studies have shown that the conventional theory of vertebrate cranial homology requires a complete reconsideration. In the course of this reexamination, we focused on the phenomenon of suture closure between bones. We were able to overturn the conventional understanding of the homology of mammalian premaxillary bone from both the macroscopic approach of comparative anatomy and palaeontology and experimental embryology. We proposed to dismiss the anatomical names given to each bone of the skull since the 18th century and to construct a new framework of cranial
bone identity based on the suture closure between the bones. The results of this study have opened the avenue to a new framework of cranial bone homology.

Academic Significance and Societal Importance of the Research Achievements

ヒトの頭蓋骨は30数個の骨パーツが認識されており,解剖学的定義づけにより各骨パーツに解剖学名称が与えられてきた.これらの名称はヒトだけでなく,他の哺乳類,鳥類,爬虫類といったあらゆる羊膜類の頭骨パーツの解剖学名称にも適用,流用されてきた.しかし,同一名称がついているからといって,相同ではないということが一部の骨について本課題により明らかとなり,同一の骨として扱うことはできないことが示された.基礎生物学にとどまらず,医学,獣医学といった応用領域にとっても極めて重要な知見であり,特に頭部おける先天形態異常の原因解明と先制治療に向けた学術的貢献が大きいといえる.

Report

(4 results)
  • 2022 Final Research Report ( PDF )
  • 2020 Annual Research Report
  • 2019 Annual Research Report
  • 2018 Annual Research Report
  • Research Products

    (31 results)

All 2023 2022 2021 2020 2019 2018 Other

All Int'l Joint Research (4 results) Journal Article (22 results) (of which Int'l Joint Research: 21 results,  Peer Reviewed: 22 results,  Open Access: 14 results) Presentation (5 results) (of which Int'l Joint Research: 5 results,  Invited: 1 results)

  • [Int'l Joint Research] ニューサウスウェールズ大学(オーストラリア)

    • Related Report
      2019 Annual Research Report
  • [Int'l Joint Research] チュービンゲン大学(ドイツ)

    • Related Report
      2019 Annual Research Report
  • [Int'l Joint Research] ベトナム科学アカデミー生態資源研究所(ベトナム)

    • Related Report
      2019 Annual Research Report
  • [Int'l Joint Research] カリフォルニア大学ロサンゼルス校(米国)

    • Related Report
      2019 Annual Research Report
  • [Journal Article] Evolution, conservatism and overlooked homologies of the mammalian skull2023

    • Author(s)
      Koyabu Daisuke
    • Journal Title

      Philosophical Transactions of the Royal Society B: Biological Sciences

      Volume: 378 Issue: 1880 Pages: 20220081-20220081

    • DOI

      10.1098/rstb.2022.0081

    • Related Report
      2020 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Caudal auricular muscle variations and the evolution of echolocation behavior in pteropodid bats2023

    • Author(s)
      CHI Tzu-Chin、TU Vuong Tan、SOHN JoonHyuk、KIMURA Junpei、KOYABU Daisuke
    • Journal Title

      Journal of Veterinary Medical Science

      Volume: 85 Issue: 6 Pages: 625-630

    • DOI

      10.1292/jvms.23-0128

    • ISSN
      0916-7250, 1347-7439
    • Related Report
      2020 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Anatomy and homology of the caudal auricular muscles in greater short-nosed fruit bat (<i>Cynopterus sphinx</i>)2023

    • Author(s)
      Tzu-Chin Chi, Fumiya Meguro, Masaki Takechi, Toshiko Furutera, Vuong Tan Tu, Hiroki Higashiyama, Joon Hyuk Sohn, Taro Nojri, Junpei Kimura*, Daisuke Koyabu*
    • Journal Title

      Journal of Veterinary Medical Science

      Volume: 85 Issue: 5 Pages: 571-577

    • DOI

      10.1292/jvms.23-0088

    • ISSN
      0916-7250, 1347-7439
    • Related Report
      2020 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] The vocal apparatus: An understudied tool to reconstruct the evolutionary history of echolocation in bats?2023

    • Author(s)
      Brualla Nicolas L. M.、Wilson Laura A. B.、Doube Michael、Carter Richard T.、McElligott Alan G.、Koyabu Daisuke
    • Journal Title

      Journal of Mammalian Evolution

      Volume: 30 Issue: 1 Pages: 79-94

    • DOI

      10.1007/s10914-022-09647-z

    • Related Report
      2020 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Synchondrosis fusion contributes to the progression of postnatal craniofacial dysmorphology in syndromic craniosynostosis.2023

    • Author(s)
      Hoshino Y, Takechi M, Moazen M, Steacy M, Koyabu D, Furutera T, Ninomiya Y, Nuri T, Pauws E, Iseki S.
    • Journal Title

      J Anat

      Volume: 242 Issue: 3 Pages: 387-401

    • DOI

      10.1111/joa.13790

    • Related Report
      2020 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Temporal and regulatory dynamics of the inner ear transcriptome during development in mice2022

    • Author(s)
      Cao Rui、Takechi Masaki、Wang Xiuwan、Furutera Toshiko、Nojiri Taro、Koyabu Daisuke、Li Jun
    • Journal Title

      Scientific Reports

      Volume: 12 Issue: 1 Pages: 1-12

    • DOI

      10.1038/s41598-022-25808-9

    • Related Report
      2020 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Evolution of the therian face through complete loss of the premaxilla2022

    • Author(s)
      Higashiyama Hiroki、Koyabu Daisuke、Kurihara Hiroki
    • Journal Title

      Evolution & Development

      Volume: 25 Issue: 1 Pages: 103-118

    • DOI

      10.1111/ede.12417

    • Related Report
      2020 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Morphological association between muscle attachments and ossification sites in the late cartilaginous skull of tuatara embryos2022

    • Author(s)
      Zhang Zitong、Yaryhin Oleksandr、Koyabu Daisuke、Werneburg Ingmar
    • Journal Title

      Journal of Morphology

      Volume: 283 Issue: 7 Pages: 908-931

    • DOI

      10.1002/jmor.21474

    • Related Report
      2020 Annual Research Report
    • Peer Reviewed / Int'l Joint Research
  • [Journal Article] Skull Sutures and Cranial Mechanics in the Permian Reptile Captorhinus aguti and the Evolution of the Temporal Region in Early Amniotes2022

    • Author(s)
      Abel Pascal、Pommery Yannick、Ford David Paul、Koyabu Daisuke、Werneburg Ingmar
    • Journal Title

      Frontiers in Ecology and Evolution

      Volume: 10

    • DOI

      10.3389/fevo.2022.841784

    • Related Report
      2020 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] On the sequence heterochrony of cranial ossification of bats in light of Haeckel's recapitulation theory.2021

    • Author(s)
      Nojiri, T., Sohn, J. H., Tu, V. T., Koyabu, D.
    • Journal Title

      Journal of Experimental Zoology Part B: Molecular and Developmental Evolution

      Volume: 4 Issue: 1-2 Pages: 1-12

    • DOI

      10.1002/jez.b.23042

    • Related Report
      2020 Annual Research Report
    • Peer Reviewed / Int'l Joint Research
  • [Journal Article] Mammalian face as an evolutionary novelty2021

    • Author(s)
      Higashiyama H, Koyabu D, Hirasawa T, Werneburg I, Kuratani S, Kurihara H
    • Journal Title

      Proceedings of the National Academy of Sciences of the United States of America

      Volume: 118 Issue: 44

    • DOI

      10.1073/pnas.2111876118

    • Related Report
      2020 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Embryonic staging of bats with special reference to Vespertilo sinensis and its cochlear development.2021

    • Author(s)
      Nojiri, T., Fukui, D., Werneburg, I., Saitoh, T., Endo, H., and Koyabu, D.
    • Journal Title

      Developmental Dynamics

      Volume: 4 Issue: 8 Pages: 1-20

    • DOI

      10.1002/dvdy.325

    • Related Report
      2020 Annual Research Report
    • Peer Reviewed / Int'l Joint Research
  • [Journal Article] Embryonic evidence uncovers convergent origins of laryngeal echolocation in bats2021

    • Author(s)
      Nojiri Taro、Wilson Laura A.B.、L?pez-Aguirre Camilo、Tu Vuong Tan、Kuratani Shigeru、Ito Kai、Higashiyama Hiroki、Son Nguyen Truong、Fukui Dai、Sadier Alexa、Sears Karen E.、Endo Hideki、Kamihori Satoshi、Koyabu Daisuke
    • Journal Title

      Current Biology

      Volume: 31 Issue: 7 Pages: 1-13

    • DOI

      10.1016/j.cub.2020.12.043

    • Related Report
      2020 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] On the embryonic development of the nasal turbinals and their homology in bats.2021

    • Author(s)
      Ito, K., Tu, V. T., Eiting, T. P., Nojiri, T., and Koyabu, D.
    • Journal Title

      Frontiers in Cell and Developmental Biology

      Volume: 9 Pages: 1-19

    • DOI

      10.3389/fcell.2021.613545

    • Related Report
      2020 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] A 1.4-million-year-old bone handaxe from Konso, Ethiopia, shows advanced tool technology in the early Acheulean2020

    • Author(s)
      Sano Katsuhiro、Beyene Yonas、Katoh Shigehiro、Koyabu Daisuke、Endo Hideki、Sasaki Tomohiko、Asfaw Berhane、Suwa Gen
    • Journal Title

      Proceedings of the National Academy of Sciences

      Volume: 117 Issue: 31 Pages: 18393-18400

    • DOI

      10.1073/pnas.2006370117

    • Related Report
      2020 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] 3D model related to the publication: three-dimensional and histological observations on male genital organs of greater horseshoe bat, Rhinolophus ferrumequinum.2020

    • Author(s)
      Joon Hyuk Sohn, Junpei Kimura, Daisuke Koyabu
    • Journal Title

      Morphomuseum

      Volume: in press Issue: 5 Pages: e113-e113

    • DOI

      10.18563/journal.m3.113

    • Related Report
      2019 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Non-invasive age estimation by cranial suture closure in Japanese sika deer (Cervus nippon).2019

    • Author(s)
      Oh, J.W., Minami, M.,Ikeda, S.,Takatsuki, S., Oonishi, N, Higuchi, N., Okada, A., Kimura, J., Koyabu, D
    • Journal Title

      Mammal Study

      Volume: 印刷中 Issue: 3 Pages: 147-147

    • DOI

      10.3106/ms2018-0065

    • NAID

      40021947477

    • Related Report
      2019 Annual Research Report 2018 Annual Research Report
    • Peer Reviewed / Int'l Joint Research
  • [Journal Article] Patterns and Constraints of Craniofacial Variation in Colobine Monkeys: Disentangling the Effects of Phylogeny, Allometry and Diet2019

    • Author(s)
      Ledevin Ronan、Koyabu Daisuke
    • Journal Title

      Evolutionary Biology

      Volume: 46 Issue: 1 Pages: 14-34

    • DOI

      10.1007/s11692-019-09469-7

    • Related Report
      2019 Annual Research Report 2018 Annual Research Report
    • Peer Reviewed / Int'l Joint Research
  • [Journal Article] Postcranial heterochrony, modularity, integration and disparity in the prenatal ossification in bats (Chiroptera)2019

    • Author(s)
      Lopez-Aguirre Camilo、Hand Suzanne J.、Koyabu Daisuke、Son Nguyen Truong、Wilson Laura A. B.
    • Journal Title

      BMC Evolutionary Biology

      Volume: 19 Issue: 1 Pages: 75-75

    • DOI

      10.1186/s12862-019-1396-1

    • Related Report
      2019 Annual Research Report 2018 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Prenatal allometric trajectories and the developmental basis of postcranial phenotypic diversity in bats (Chiroptera)2019

    • Author(s)
      Lopez-Aguirre Camilo、Hand Suzanne J.、Koyabu Daisuke、Son Nguyen Truong、Wilson Laura A. B.
    • Journal Title

      Journal of Experimental Zoology Part B: Molecular and Developmental Evolution

      Volume: 332 Issue: 1-2 Pages: 36-49

    • DOI

      10.1002/jez.b.22846

    • Related Report
      2019 Annual Research Report 2018 Annual Research Report
    • Peer Reviewed / Int'l Joint Research
  • [Journal Article] Biogeographic variation in skull morphology across the Kra Isthmus in dusky leaf monkeys.2018

    • Author(s)
      Ito, T., Koyabu, D.
    • Journal Title

      Journal of Zoological Systematics and Evolutionary Research

      Volume: in press Issue: 4 Pages: 599-610

    • DOI

      10.1111/jzs.12229

    • NAID

      120006715529

    • Related Report
      2018 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Prenatal cranial bone development of Thomas’s horseshoe bat (Rhinolophus thomasi): with special reference to petrosal morphology.2018

    • Author(s)
      Nojiri, T., Werneburg, I., Son, N.T., Tu, V.T., Sasaki, T., Maekawa, Y., Koyabu, D.
    • Journal Title

      Journal of Morphology

      Volume: in press Issue: 6 Pages: 809-827

    • DOI

      10.1002/jmor.20813

    • Related Report
      2018 Annual Research Report
    • Peer Reviewed / Int'l Joint Research
  • [Presentation] Evolution of the temporal region in the early amniote skull2019

    • Author(s)
      Pascal Abel, Daisuke Koyabu, Ingmar Werneburg.
    • Organizer
      ドイツ古生物学会年次大会
    • Related Report
      2019 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Prenatal Development of Echolocation-Related Traits in Bats and the Origin of Laryngeal Echolocation: Single Origin or Convergence?2019

    • Author(s)
      Koyabu D, Nojiri T.
    • Organizer
      国際脊椎動物形態学会
    • Related Report
      2019 Annual Research Report
    • Int'l Joint Research
  • [Presentation] The Morphogenetic Basis of Mammalian Flight: Allometric Trajectories and Ossification Heterochronies in Prenatal Skeletogenesis of Bats2019

    • Author(s)
      Lopez-Aguirre C, Wilson LAB, Koyabu D, Hand SJ.
    • Organizer
      国際脊椎動物形態学会
    • Related Report
      2019 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Does Prenatal Development Support a Single Origin of Laryngeal Echolocation in Bats?2019

    • Author(s)
      Nojiri T, Koyabu D.
    • Organizer
      国際脊椎動物形態学会
    • Related Report
      2019 Annual Research Report
    • Int'l Joint Research
  • [Presentation] On the Development of the Nasal Capsule and Turbinate Homology in Laurasiatherians, with Special Reference to Bats2019

    • Author(s)
      Ito K, Nojiri T, Koyabu D.
    • Organizer
      国際脊椎動物形態学会
    • Related Report
      2019 Annual Research Report
    • Int'l Joint Research / Invited

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Published: 2018-04-23   Modified: 2024-01-30  

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