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Digitalization of infant and school age health check-up records as foundation for evidence based preventive medicine

Research Project

Project/Area Number 18H03049
Research Category

Grant-in-Aid for Scientific Research (B)

Allocation TypeSingle-year Grants
Section一般
Review Section Basic Section 58030:Hygiene and public health-related: excluding laboratory approach
Research InstitutionKyoto University

Principal Investigator

Kawakami Koji  京都大学, 医学研究科, 教授 (70422318)

Project Period (FY) 2018-04-01 – 2021-03-31
Project Status Completed (Fiscal Year 2020)
Budget Amount *help
¥15,600,000 (Direct Cost: ¥12,000,000、Indirect Cost: ¥3,600,000)
Fiscal Year 2020: ¥4,940,000 (Direct Cost: ¥3,800,000、Indirect Cost: ¥1,140,000)
Fiscal Year 2019: ¥5,070,000 (Direct Cost: ¥3,900,000、Indirect Cost: ¥1,170,000)
Fiscal Year 2018: ¥5,590,000 (Direct Cost: ¥4,300,000、Indirect Cost: ¥1,290,000)
Keywords学校健診 / 母子保健 / 乳幼児健診 / デジタルトランスフォーメーション / ライフコースデータ / 公衆衛生 / 疫学 / ビッグデータ / 疫学研究 / 学校保健 / 健康診断
Outline of Final Research Achievements

Consociating with local municipalities, we digitalized infant and school age health check-up records which have been abandoned for many years. Then, we built a database that can follow up the health of infants to junior high school students. As of March 2021, we have partnered with 146 local municipalities.

We used early childhood and school age health check-up data in Hofu City, to investigate the association of obesity at age 15 years with low/high birth weight, obesity in 3 years of age and obesity in mothers. In result, obesity in mothers and obesity at 3 years of age, but not birth weight, were associated with obesity at age 15 years.

Academic Significance and Societal Importance of the Research Achievements

近年、成人期の慢性疾患発症には胎生期や乳幼児期の環境や因子が大きく影響すると考えられている。これらを検証するために国内外で地域単位の研究が存在するが、子どもの健康情報を法制度に基づいて悉皆で取得する制度は世界でも稀であり、国家規模での健診事業に基づいた子どもの健康データベース構築を実施し得るのは日本だけである。構築したデータベースは、胎内や乳幼児期の環境や生活習慣と長期的な発育の関連を追跡調査できる、世界的にも貴重な疫学研究の大規模な基盤となる。また、予防医療による健康寿命延伸や自治体や国の健康政策策定の根拠としても寄与し得る。

Report

(4 results)
  • 2020 Annual Research Report   Final Research Report ( PDF )
  • 2019 Annual Research Report
  • 2018 Annual Research Report
  • Research Products

    (12 results)

All 2020 2019 2018

All Journal Article (8 results) (of which Int'l Joint Research: 2 results,  Peer Reviewed: 8 results,  Open Access: 8 results) Presentation (1 results) (of which Invited: 1 results) Book (3 results)

  • [Journal Article] Association of maternal prepregnancy weight and early childhood weight with obesity in adolescence: A population‐based longitudinal cohort study in Japan2020

    • Author(s)
      Yoshida Satomi、Kimura Takeshi、Noda Masahiro、Takeuchi Masato、Kawakami Koji
    • Journal Title

      Pediatric Obesity

      Volume: 15(4) Issue: 4

    • DOI

      10.1111/ijpo.12597

    • Related Report
      2020 Annual Research Report 2019 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Utilization and efficacy of palivizumab for children with Down syndrome2020

    • Author(s)
      Kimura Takeshi、Takeuchi Masato、Kawakami Koji
    • Journal Title

      Pediatrics International

      Volume: - Issue: 6 Pages: 677-682

    • DOI

      10.1111/ped.14157

    • Related Report
      2019 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Maternal multivitamin intake and orofacial clefts in offspring: Japan Environment and Children's Study (JECS) cohort study.2020

    • Author(s)
      Satomi Yoshida, Masato Takeuchi, Koji Kawakami, Shunichi Ito, Japan Environment & Children's Study Group.
    • Journal Title

      Japan Environment & Children's Study (JECS)

      Volume: 10(3)

    • NAID

      120006885395

    • Related Report
      2019 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Association of Low Birth Weight With Childhood Proteinuria at Age 3 Years: A Population-Based Retrospective Cohort Study2019

    • Author(s)
      Shinzawa Maki、Tanaka Shiro、Tokumasu Hironobu、Takada Daisuke、Tsukamoto Tatsuo、Yanagita Motoko、Kawakami Koji
    • Journal Title

      American Journal of Kidney Diseases

      Volume: 74 Issue: 1 Pages: 141-143

    • DOI

      10.1053/j.ajkd.2019.02.018

    • Related Report
      2019 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Association between antidepressant use during pregnancy and autism spectrum disorder in children: a retrospective cohort study based on Japanese claims data2019

    • Author(s)
      Yamamoto-Sasaki Madoka、Yoshida Satomi、Takeuchi Masato、Tanaka-Mizuno Sachiko、Ogawa Yusuke、Furukawa Toshiaki A.、Kawakami Koji
    • Journal Title

      Maternal Health, Neonatology and Perinatology

      Volume: 5 Issue: 1

    • DOI

      10.1186/s40748-018-0096-y

    • Related Report
      2019 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Exposure to tobacco smoke prenatally and during infancy and risk of hearing impairment among children in Japan: A retrospective cohort study2018

    • Author(s)
      Wilunda Calistus、Yoshida Satomi、Tanaka Shiro、Kanazawa Yuji、Kimura Takeshi、Kawakami Koji
    • Journal Title

      Paediatric and Perinatal Epidemiology

      Volume: 32 Issue: 5 Pages: 430-438

    • DOI

      10.1111/ppe.12477

    • Related Report
      2018 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Prenatal and early-life antibiotic use and risk of childhood asthma: A retrospective cohort study.2018

    • Author(s)
      Satomi Yoshida, Kazuki Ide, Masato Takeuchi, Koji Kawakami.
    • Journal Title

      Pediatric Allergy and Immunology.

      Volume: in press Issue: 5 Pages: 490-495

    • DOI

      10.1111/pai.12902

    • Related Report
      2018 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Insufficient Sleep and Incidence of Dental Caries in Deciduous Teeth among Children in Japan: A Population-Based Cohort Study.2018

    • Author(s)
      Chen H, Tanaka S, Arai K, Yoshida S, Kawakami K
    • Journal Title

      J Pediatr

      Volume: 198 Pages: 279-286

    • Related Report
      2018 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Presentation] 自治体での母子保健・学校健診、医療現場の情報の可視化と疫学への応用2018

    • Author(s)
      川上 浩司
    • Organizer
      第77回日本公衆衛生学会総会
    • Related Report
      2018 Annual Research Report
    • Invited
  • [Book] 国際文化研修2019

    • Author(s)
      祐野 恵, 川上 浩司
    • Total Pages
      49
    • Publisher
      国際文化研修
    • Related Report
      2018 Annual Research Report
  • [Book] 医学のあゆみ2018

    • Author(s)
      川上 浩司
    • Total Pages
      5
    • Publisher
      医学のあゆみ
    • Related Report
      2018 Annual Research Report
  • [Book] 近畿情報通信協議会誌KICC2018

    • Author(s)
      川上 浩司
    • Total Pages
      3
    • Publisher
      近畿情報通信協議会
    • Related Report
      2018 Annual Research Report

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Published: 2018-04-23   Modified: 2022-01-27  

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