| Budget Amount *help |
¥191,880,000 (Direct Cost: ¥147,600,000、Indirect Cost: ¥44,280,000)
Fiscal Year 2022: ¥41,730,000 (Direct Cost: ¥32,100,000、Indirect Cost: ¥9,630,000)
Fiscal Year 2021: ¥41,730,000 (Direct Cost: ¥32,100,000、Indirect Cost: ¥9,630,000)
Fiscal Year 2020: ¥41,730,000 (Direct Cost: ¥32,100,000、Indirect Cost: ¥9,630,000)
Fiscal Year 2019: ¥41,730,000 (Direct Cost: ¥32,100,000、Indirect Cost: ¥9,630,000)
Fiscal Year 2018: ¥24,960,000 (Direct Cost: ¥19,200,000、Indirect Cost: ¥5,760,000)
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| Outline of Final Research Achievements |
The aim of this study was to elucidate molecular and neural bases of primer pheromones that induce physiological changes in mammals. In mice, we obtained structural knowledge of pheromone molecules involved in the promotion of sexual maturation and induction and suppression of estrus, and clarified their receptors and neural basis. We found that the molecules are also involved in male-to-male aggression. To identify pheromone molecules involved in pregnancy inhibition, we obtained new knowledge on the mechanism of memory acquisition in mating partners. We identified body odor molecules that change with the sexual cycle in humans, and found that these odors cause physiological and psychological effects.
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