|Budget Amount *help
¥4,420,000 (Direct Cost: ¥3,400,000、Indirect Cost: ¥1,020,000)
Fiscal Year 2020: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2019: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Fiscal Year 2018: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
|Outline of Final Research Achievements
Immature teratoma of the ovary is a malignant tumor that develops in the ovaries of young people. The embryonic neuroectoderm component defines malignancy. However, the genetic abnormality of immature teratoma is not clear. On the other hand, 19q13.42 amplification has already been clarified as a genetic abnormality of pediatric brain tumors that mainly differentiate into the embryonic neuroectoderm component. We wanted to clarify whether the abnormality was found in the neuroectoderm component of immature teratoma, and examined it in 30 cases. The analysis result by FISH was that there was no amplification of 19q13.42 in all 30 cases.