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Understanding Public Opinion and Generating Debate Over the Handling of Germ Cells and Embryos Derived from Human Pluripotent Stem Cells

Research Project

Project/Area Number 18K10000
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeMulti-year Fund
Section一般
Review Section Basic Section 58010:Medical management and medical sociology-related
Research InstitutionKyoto University

Principal Investigator

Fujita Misao  京都大学, iPS細胞研究所, 特定教授 (50396701)

Project Period (FY) 2018-04-01 – 2021-03-31
Project Status Completed (Fiscal Year 2020)
Budget Amount *help
¥4,420,000 (Direct Cost: ¥3,400,000、Indirect Cost: ¥1,020,000)
Fiscal Year 2020: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2019: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
Fiscal Year 2018: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
KeywordsiPS細胞 / 生殖細胞 / ヒト胚 / 生命倫理学 / 質問紙調査
Outline of Final Research Achievements

(A) Attitude survey on human germ cell production: A questionnaire survey was conducted among 3,096 general citizens. Nearly 80% of the participants answered that they would allow the cells to be produced; about 50% of the participants claimed that they would allow fertilization and approximately 25% of the participants claimed that they would allow childbirth. The majority of the participants expected basic research, and about 20% expected clinical applications. (B) Attitude survey on genome-editing technology: A questionnaire survey was conducted with 4,424 general citizens and 98 researchers involved in genome-editing research. The former group was found to be more cautious when it came to using the technology than the latter. (C) Development of outreach programs on the ethical challenges of artificial germ cells and genome editing: 90 minutes of educational material on germ cell production was created, and lectures and small group discussions were conducted for the general public.

Academic Significance and Societal Importance of the Research Achievements

(1)人工生殖細胞作製研究やヒト胚へのゲノム編集技術の倫理的課題に対する民意を明らかにできる。これにより、一般市民の意向を進行中の規制策定の議論に反映させ、当該技術の健全な発展に寄与することができる。(2)開発したアウトリーチ・プログラムを、第三者が利用できるよう公開することで、当該技術の倫理的課題について社会で共有し、議論の場を広げることができる。(3)当該技術の倫理的課題に関する質問紙調査や一般市民に向けたアウトリーチ・プログラムは国内にも例が少なく、国際的に急成長を遂げる多能性幹細胞研究の質の向上に貢献することができる。

Report

(4 results)
  • 2020 Annual Research Report   Final Research Report ( PDF )
  • 2019 Research-status Report
  • 2018 Research-status Report
  • Research Products

    (12 results)

All 2019 Other

All Presentation (6 results) (of which Int'l Joint Research: 2 results,  Invited: 1 results) Remarks (6 results)

  • [Presentation] Public survey in Japan on human genome editing for research purposes.2019

    • Author(s)
      Sawai T, Akatsuka K, Hatta T, Fujita M.
    • Organizer
      ISSCR 2019 Annual Meeting
    • Related Report
      2019 Research-status Report
    • Int'l Joint Research
  • [Presentation] Public survey in Japan on human genome editing for research purposes.2019

    • Author(s)
      Akatsuka K, Sawai T, Hatta T, Fujita M.
    • Organizer
      ISSCR 2019 Annual Meeting
    • Related Report
      2019 Research-status Report
    • Int'l Joint Research
  • [Presentation] Public attitudes in Japan toward the creation and use of human iPS cell-derived gametes.2019

    • Author(s)
      Sawai T, Hatta T, Akatsuka K, Fujita M.
    • Organizer
      FY2019 SiteVisit to WPI-ASHBi
    • Related Report
      2019 Research-status Report
  • [Presentation] Public survey in Japan on human genome editing for research purposes.2019

    • Author(s)
      Akatsuka K, Sawai T, Hatta T, Fujita M.
    • Organizer
      FY2019 SiteVisit to WPI-ASHBi
    • Related Report
      2019 Research-status Report
  • [Presentation] Public awareness and acceptance of the creation and use of human iPS cell-derived gametes in Japan.2019

    • Author(s)
      Hatta T, Sawai T, Akatsuka K, Fujita M.
    • Organizer
      FY2019 SiteVisit to WPI-ASHBi
    • Related Report
      2019 Research-status Report
  • [Presentation] 医療倫理:iPS細胞研究の倫理2019

    • Author(s)
      藤田みさお
    • Organizer
      第120回日本耳鼻咽喉科学会総会・学術講演会
    • Related Report
      2019 Research-status Report
    • Invited
  • [Remarks] 京都大学iPS細胞研究所

    • URL

      https://www.cira.kyoto-u.ac.jp/

    • Related Report
      2020 Annual Research Report 2019 Research-status Report
  • [Remarks] 京都大学iPS細胞研究所 上廣倫理研究部門

    • URL

      https://www.cira.kyoto-u.ac.jp/uehiro-ethics/

    • Related Report
      2020 Annual Research Report
  • [Remarks] 京都大学高等研究院 ヒト生物学高等研究拠点

    • URL

      https://ashbi.kyoto-u.ac.jp/

    • Related Report
      2020 Annual Research Report
  • [Remarks] 京都大学iPS細胞研究所 上廣倫理研究部門

    • URL

      https://www.cira.kyoto-u.ac.jp/uehiro-ethics/

    • Related Report
      2019 Research-status Report
  • [Remarks] 京都大学高等研究院ヒトー生物高等研究拠点

    • URL

      https://ashbi.kyoto-u.ac.jp/ja/

    • Related Report
      2019 Research-status Report
  • [Remarks] 京都大学iPS細胞研究所上廣倫理研究部門

    • URL

      http://www.cira.kyoto-u.ac.jp/uehiro-ethics/

    • Related Report
      2018 Research-status Report

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Published: 2018-04-23   Modified: 2022-01-27  

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