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Evaluation of glucose and fat metabolism using breath acetone concentration

Research Project

Project/Area Number 18K19763
Research Category

Grant-in-Aid for Challenging Research (Exploratory)

Allocation TypeMulti-year Fund
Review Section Medium-sized Section 59:Sports sciences, physical education, health sciences, and related fields
Research InstitutionRitsumeikan University

Principal Investigator

GOTO KAZUSHIGE  立命館大学, スポーツ健康科学部, 教授 (60508258)

Project Period (FY) 2018-06-29 – 2020-03-31
Project Status Completed (Fiscal Year 2019)
Budget Amount *help
¥6,240,000 (Direct Cost: ¥4,800,000、Indirect Cost: ¥1,440,000)
Fiscal Year 2019: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
Fiscal Year 2018: ¥4,550,000 (Direct Cost: ¥3,500,000、Indirect Cost: ¥1,050,000)
Keywords呼気中アセトン濃度 / ケトン体 / 持久性運動 / 短時間・高強度運動 / リカバリー / 呼気中アセトン / 運動 / 糖代謝 / 脂質代謝 / 筋グリコーゲン / 呼気アセトン
Outline of Final Research Achievements

The present study determined the effect of acute exercise on breath acetone concentration, carbohydrate and fat metabolism during post-exercise. The influence of different carbohydrate intake on breath acetone concentration was also evaluated. Consequently, carbohydrate restriction following high-intensity interval exercise and endurance exercise increased breath acetone concentration. Moreover, the findings suggest that time-course changes in breath acetone concentration during post-exercise reflect carbohydrate availability and recovery of endurance capacity.

Academic Significance and Societal Importance of the Research Achievements

本研究の結果、短時間・高強度運動や長時間の持久性運動後に呼気中アセトン濃度の上昇することが明らかになった。このことは、運動に伴う脂質代謝の亢進を反映すると考えられる。呼気中アセトン濃度の評価には採血の必要がなく、簡易に実施することが可能である。今後は、呼気アセトン濃度を指標として、運動に伴う糖・脂質代謝の変化や疲労からの回復の程度を評価する試みが期待される。

Report

(3 results)
  • 2019 Annual Research Report   Final Research Report ( PDF )
  • 2018 Research-status Report
  • Research Products

    (10 results)

All 2020 2019 2018

All Journal Article (3 results) (of which Peer Reviewed: 3 results,  Open Access: 1 results) Presentation (7 results) (of which Int'l Joint Research: 5 results,  Invited: 1 results)

  • [Journal Article] Muscle glycogen content during endurance training under low energy availability2020

    • Author(s)
      Chihiro Kojima, Aya Ishibashi, Yoko Tanabe, Kaito Iwayama, Akiko Kamei, Hideyuki Takahashi, Kazushige Goto
    • Journal Title

      Med. Sci. Sports Exerc.

      Volume: 52 Issue: 1 Pages: 187-195

    • DOI

      10.1249/mss.0000000000002098

    • Related Report
      2019 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Effects of diet before endurance exercise on hepcidin response in young untrained females.2018

    • Author(s)
      Hayashi N, Ishibashi A, Goto K
    • Journal Title

      Journal of Exercise Nutrition and Biochemistry

      Volume: 22 Issue: 4 Pages: 55-61

    • DOI

      10.20463/jenb.2018.0030

    • Related Report
      2018 Research-status Report
    • Peer Reviewed
  • [Journal Article] Metabolic and Performance Responses to Sprint Exercise under Hypoxia among Female Athletes.2018

    • Author(s)
      Kasai N, Kojima C, Goto K
    • Journal Title

      Sports Medicine International Open

      Volume: 2 Issue: 03 Pages: E71-E78

    • DOI

      10.1055/a-0628-6100

    • Related Report
      2018 Research-status Report
    • Peer Reviewed / Open Access
  • [Presentation] Impact of reduced carbohydrate intake after exercise on breath acetone levels2019

    • Author(s)
      Ota N, Ito H, Goto K
    • Organizer
      66th Annual meeting of American College of Sports Medicine
    • Related Report
      2019 Annual Research Report
    • Int'l Joint Research
  • [Presentation] 低酸素環境や暑熱環境下で行う運動に対する代謝応答2019

    • Author(s)
      後藤一成
    • Organizer
      第27回日本運動生理学会大会
    • Related Report
      2019 Annual Research Report
    • Invited
  • [Presentation] Exogenous glucose oxidaiton duirng endurance exercise in hypoxia2019

    • Author(s)
      Sumi D, Hayashi N, Yatsutani H, Goto K
    • Organizer
      66th Annual meeting of American College of Sports Medicine
    • Related Report
      2019 Annual Research Report
    • Int'l Joint Research
  • [Presentation] 高強度や長時間の運動が食欲調節に及ぼす影響-運動に伴う食欲減退とその打開策-2018

    • Author(s)
      後藤一成
    • Organizer
      第73回日本体力医学会大会
    • Related Report
      2018 Research-status Report
  • [Presentation] Impact of Hypoxia on Glucose Metabolism, Appetite Regulations, Muscle Damage and Inflammatory Responses2018

    • Author(s)
      Goto K
    • Organizer
      65th Annual Meeting of American College of Sports Medicine
    • Related Report
      2018 Research-status Report
    • Int'l Joint Research
  • [Presentation] Effect of low energy availability duirng three consecutive days of endurance training on muscle glycogen contents and serum hepcidin levels in male long distance runners.2018

    • Author(s)
      Ishibashi A, Kojima C, Kamei A, Iwayama K, Tanabe Y, Goto K, Takahashi H
    • Organizer
      65th Annual Meeting of American College of Sports Medicine
    • Related Report
      2018 Research-status Report
    • Int'l Joint Research
  • [Presentation] Effects of diet before endurance exercise on hepcidin response in young females.2018

    • Author(s)
      Hayashi N, Goto K
    • Organizer
      65th Annual Meeting of American College of Sports Medicine
    • Related Report
      2018 Research-status Report
    • Int'l Joint Research

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Published: 2018-07-25   Modified: 2021-02-19  

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