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Molecular Analysis of Light-signaling and Circadian Rhythm in theBrain

Research Project

Project/Area Number 19107002
Research Category

Grant-in-Aid for Scientific Research (S)

Allocation TypeSingle-year Grants
Research Field Animal physiology/Animal behavior
Research InstitutionThe University of Tokyo

Principal Investigator

FUKADA Yoshitaka  東京大学, 大学院・理学系研究科, 教授 (80165258)

Co-Investigator(Kenkyū-buntansha) KOJIMA Daisuke  東京大学, 大学院・理学系研究科, 講師 (60376530)
Co-Investigator(Renkei-kenkyūsha) KOJIMA Daisuke  東京大学, 大学院・理学系研究科, 講師 (60376530)
SHIMIZU Kimiko  東京大学, 大学院・理学系研究科, 助教 (50451828)
YOSHITANE Hikari  東京大学, 大学院・理学系研究科, 助教 (70569920)
Project Period (FY) 2007 – 2011
Project Status Completed (Fiscal Year 2011)
Budget Amount *help
¥106,080,000 (Direct Cost: ¥81,600,000、Indirect Cost: ¥24,480,000)
Fiscal Year 2011: ¥19,500,000 (Direct Cost: ¥15,000,000、Indirect Cost: ¥4,500,000)
Fiscal Year 2010: ¥19,240,000 (Direct Cost: ¥14,800,000、Indirect Cost: ¥4,440,000)
Fiscal Year 2009: ¥20,280,000 (Direct Cost: ¥15,600,000、Indirect Cost: ¥4,680,000)
Fiscal Year 2008: ¥20,280,000 (Direct Cost: ¥15,600,000、Indirect Cost: ¥4,680,000)
Fiscal Year 2007: ¥26,780,000 (Direct Cost: ¥20,600,000、Indirect Cost: ¥6,180,000)
Keywords脳・神経 / 視覚 / 光 / シグナル伝達 / サーカディアンリズム / 転写因子 / タンパク質リン酸化 / 松果体 / 網膜 / 視細胞 / 動物生理 / 化学 / 位相シフト / 視覚網膜 / 位相シフト制御 / TGF-β / 翻訳後修飾
Research Abstract

In this study, we aimed at molecular level understanding of the photoreception systems in animals. Particularly we raised three projects: 1) Elucidation of unique gene networks that specify photoreceptor functions between the pineal gland and the retina, 2) Elucidation of the regulatory mechanisms for circadian clock phase, 3) Characterization of light-response properties in photoreceptive cells in the retina. The major outputs from our studies are: 1) Identification of transcription factors that govern the pineal specific gene expression, 2) Identification of multiple proteins regulating the clock phase and elucidation of the underlying mechanisms for the phase-shift, 3) Clarification of a mechanism that provides a difference of photoreceptive properties between retinal rods and cones.

Assessment Rating
Verification Result (Rating)

A

Report

(8 results)
  • 2013 Research Progress Assessment (Verification Result) ( PDF )
  • 2011 Annual Research Report   Final Research Report ( PDF )
  • 2010 Annual Research Report
  • 2009 Annual Research Report   Self-evaluation Report ( PDF )
  • 2008 Annual Research Report
  • 2007 Annual Research Report
  • Research Products

    (183 results)

All 2012 2011 2010 2009 2008 2007 Other

All Journal Article (60 results) (of which Peer Reviewed: 44 results) Presentation (107 results) (of which Invited: 5 results) Book (8 results) Remarks (7 results) Patent(Industrial Property Rights) (1 results)

  • [Journal Article] JNK regulates the photic response of the mammalian circadian clock2012

    • Author(s)
      Yoshitane, H., Honma, S., Fukada, Y., 他11名、6番目
    • Journal Title

      EMBO Rep.

      Volume: (印刷中) Issue: 5 Pages: 455-461

    • DOI

      10.1038/embor.2012.37

    • Related Report
      2011 Annual Research Report 2011 Final Research Report
    • Peer Reviewed
  • [Journal Article] Highly sensitive detection of protein phosphorylation by using improved Phos-tag Biotin2012

    • Author(s)
      Kinoshita,E., Fukada,Y.
    • Journal Title

      Proteomics

      Volume: 12 Pages: 932-937

    • Related Report
      2011 Final Research Report
    • Peer Reviewed
  • [Journal Article] Highly sensitive detection of protein phosphorylation by using improved Phos-tag Biotin.2012

    • Author(s)
      Eiji Kinoshita
    • Journal Title

      Proteomics

      Volume: 12 Pages: 932-937

    • Related Report
      2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] (*equalcontribution) Light-dependent and circadian clock-regulated activation of sterol regulatory element-binding protein, X-box-binding protein 1 and heat shock factor pathways2011

    • Author(s)
      Hatori,M.*, Hirota,T., Fukada,Y.
    • Journal Title

      Proc. Natl. Acad. Sci. USA.

      Volume: 108 Issue: 12 Pages: 4864-4869

    • DOI

      10.1073/pnas.1015959108

    • Related Report
      2011 Annual Research Report 2011 Final Research Report
    • Peer Reviewed
  • [Journal Article] (*equal contribution; #corresponding authors) Ectopic expression of the cone-specific Gprotein-coupled receptor kinase GRK7 in zebrafish rods leads to decreased photosensitivity and compromised visual performance2011

    • Author(s)
      Vogalis,F., Shiraki,T., Kojima,D., Fukada,Y. & Lamb,T.
    • Journal Title

      J. Physiol. (London)

      Volume: 589 Issue: 9 Pages: 2321-2348

    • DOI

      10.1113/jphysiol.2010.204156

    • Related Report
      2011 Annual Research Report 2011 Final Research Report
    • Peer Reviewed
  • [Journal Article] (*equal contribution; #corresponding authors)UV-sensitive photoreceptor protein OPN5 in humans and mice2011

    • Author(s)
      Kojima,D.*#, Mori,S.*, Torii,M.*, Wada,A., Morishita,R. & Fukada,Y.#
    • Journal Title

      PLoS One

      Volume: 6 Issue: 10 Pages: e26388-e26388

    • DOI

      10.1371/journal.pone.0026388

    • Related Report
      2011 Annual Research Report 2011 Final Research Report
    • Peer Reviewed
  • [Journal Article] 概日時計の分子サイクルを支えるリズミックなタンパク質分解2011

    • Author(s)
      倉林 伸博
    • Journal Title

      実験医学

      Volume: 29 Pages: 147-151

    • Related Report
      2011 Annual Research Report
  • [Journal Article] Light-dependent and circadian clock-regulated activation of SREBP, XBP1 and HSF pathways in the pineal gland2011

    • Author(s)
      Megumi Hatori, Tsuyoshi Hirota(同等貢献)
    • Journal Title

      Proc.Natl.Acad.Sci.USA

      Volume: (in press)(掲載確定)

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Ectopic expression of the cone specific G-protein-coupled receptor kinase GRK7 in zebrafish rods leads to decreased photosensitivity and compromised visual performance2011

    • Author(s)
      Fivos Vogalis, Tomoya Shiraki, Daisuke Kojima(同等貢献)
    • Journal Title

      J.Physiol.

      Volume: (in press)(掲載確定)

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Light-induced body color change in developing zebrafish2010

    • Author(s)
      Shiraki,T., Kojima,D. and Fukada,Y
    • Journal Title

      Photochem.Photobiol. Sci.

      Volume: 9 Issue: 11 Pages: 1498-1504

    • DOI

      10.1039/c0pp00199f

    • Related Report
      2011 Final Research Report
    • Peer Reviewed
  • [Journal Article] DYRK1A and GSK-3ss: A dualkinase mechanism directing proteasomal degradation of CRY2 for circadian timekeeping2010

    • Author(s)
      Kurabayashi,N., Fukada Y.
    • Journal Title

      Mol. Cell. Biol.

      Volume: 30 Issue: 7 Pages: 1757-1768

    • DOI

      10.1128/mcb.01047-09

    • Related Report
      2011 Final Research Report
    • Peer Reviewed
  • [Journal Article] Transcriptional repressor TIEG1 regulates Bmal1 gene through GC box and controlscircadian clockwork2010

    • Author(s)
      Hirota,T.,, Fukada,Y.
    • Journal Title

      Genes Cells

      Volume: 15 Issue: 2 Pages: 111-121

    • DOI

      10.1111/j.1365-2443.2009.01371.x

    • Related Report
      2011 Final Research Report
    • Peer Reviewed
  • [Journal Article] Transcriptional repressor TIEG1 regulates Bmall gene through GC box andcontrols circadian clockwork2010

    • Author(s)
      Tsuyoshi Hirota
    • Journal Title

      Genes Cells

      Volume: 15 Pages: 111-121

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] DYRK1A and GSK-3β:A dual kinase mechanism directing proteasomal degradation of CRY2 for circadian timekeeping2010

    • Author(s)
      Nobuhiro Kurabayashi
    • Journal Title

      Mol.Cell.Biol.

      Volume: 30 Pages: 1757-1768

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Light-induced body color change in developing zebrafish2010

    • Author(s)
      Tomoya Shiraki
    • Journal Title

      Photochem.Photobiol.Sci.

      Volume: 9 Pages: 1498-1504

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] 概日時計の時刻リセットの分子機構2010

    • Author(s)
      金尚弘
    • Journal Title

      比較内分泌学

      Volume: 36 Pages: 118-126

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article]2010

    • Author(s)
      Kurabayashi, N., Hirota, T., Sakai, M., Sanada, K., Fukada Y.
    • Journal Title

      Mol.Cell.Biol. 30

      Pages: 1757-1768

    • Related Report
      2009 Self-evaluation Report
  • [Journal Article]2010

    • Author(s)
      Hirota, T., Kon, N., Itagaki, T., Hoshina, N., Okano, T., Fukada, Y.
    • Journal Title

      Genes Cells 15

      Pages: 111-121

    • Related Report
      2009 Self-evaluation Report
  • [Journal Article] DYRK1A and GSK-3β : A dual kinase mechanism directing proteasomal degradation of CRY2 for circadian timeke eping2010

    • Author(s)
      Nobuhiro Kurabayashi
    • Journal Title

      Mol.Cell.Biol. 30

      Pages: 1757-1768

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Transcriptional repressor TIEG1 regulates Bmal1 gene through GC box and controls circadian clockwork2010

    • Author(s)
      Tsuyoshi Hirota
    • Journal Title

      Genes Cells 15

      Pages: 111-121

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] SCOP/PHLPP and its functional role in the brain2010

    • Author(s)
      Kimiko Shimizu
    • Journal Title

      Molecular Biosystems 6

      Pages: 38-43

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article]2010

    • Author(s)
      小島大輔
    • Journal Title

      比較生理生化学 27巻、『ゼブラフィッシュの飼育』(比較生理生化学会)

      Pages: 28-31

    • Related Report
      2009 Annual Research Report
  • [Journal Article] Preferential inhibition of BMAL2:CLOCK activity by PER2 reemphasizes its negativerole and a positive role of BMAL2 in the circadian transcription2009

    • Author(s)
      Sasaki,M., Fukada,Y.
    • Journal Title

      J. Biol. Chem.

      Volume: 284 Issue: 37 Pages: 25149-25159

    • DOI

      10.1074/jbc.m109.040758

    • Related Report
      2011 Final Research Report
    • Peer Reviewed
  • [Journal Article] Roles of CLOCK phosphorylation in suppression of E-box-dependent transcription2009

    • Author(s)
      Yoshitane,H., Fukada,Y.
    • Journal Title

      Mol. Cell. Biol.

      Volume: 29 Issue: 13 Pages: 3675-3686

    • DOI

      10.1128/mcb.01864-08

    • Related Report
      2011 Final Research Report
    • Peer Reviewed
  • [Journal Article]2009

    • Author(s)
      Yoshitane, H., Takao, T., Satomi, Y., Du, N. H., Okano, T., Fukada, Y.
    • Journal Title

      Mol.Cell.Biol. 29

      Pages: 3675-3686

    • Related Report
      2009 Self-evaluation Report
  • [Journal Article] Roles of CLOCK phosphorylation in suppression of E-box-dependent transcription2009

    • Author(s)
      Hikari Yoshitane
    • Journal Title

      Mol.Cell.Biol. 29

      Pages: 3675-3686

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Preferential inhibition of BMAL2 : CLOCK activity by PER2 reemphasizes its negative role and a positive role of BMAL2 in the circadian transcription2009

    • Author(s)
      Momoko Sasaki
    • Journal Title

      J.Biol.Chem. 284

      Pages: 25149-25159

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] CIPC-dependent phosphorylation of CLOCK and NPAS2 in circadian clockwork2009

    • Author(s)
      Hikari Yoshitane
    • Journal Title

      Sleep Biol.Rhythms 7

      Pages: 226-234

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article]2009

    • Author(s)
      鳥居雅樹
    • Journal Title

      『動物の多様な生き方』第1巻「見える光、見えない光」第2章 3.時を刻む体内時計(共立出版)

      Pages: 154-173

    • Related Report
      2009 Annual Research Report
  • [Journal Article]2009

    • Author(s)
      深田吉孝
    • Journal Title

      生体の科学、Vol.59、No.6、特集『mTORをめぐるシグナルタンパク』LKB1と神経細胞移動(医学書院)

      Pages: 511-515

    • Related Report
      2009 Annual Research Report
  • [Journal Article]2009

    • Author(s)
      小島大輔
    • Journal Title

      『動物の多様な生き方』第1巻「見える光、見えない光」第3章 1.光による体色のコントロール(共立出版)

      Pages: 209-221

    • Related Report
      2009 Annual Research Report
  • [Journal Article] Activation of TGF-ss/activin signalling resets the circadian clock through rapidinduction of Dec1 transcripts2008

    • Author(s)
      Kon,N., Fukada,Y.
    • Journal Title

      Nature Cell Biol.

      Volume: 10 Issue: 12 Pages: 1463-1469

    • DOI

      10.1038/ncb1806

    • Related Report
      2011 Final Research Report
    • Peer Reviewed
  • [Journal Article] (*equal contribution; #corresponding authors) Time-of-day-dependent enhancement of adult neurogenesis in the hippocampus2008

    • Author(s)
      Tamai,S.*, Sanada,K.*# & Fukada,Y.#
    • Journal Title

      PLoS One

      Volume: 3 Issue: 12 Pages: e3835-e3835

    • DOI

      10.1371/journal.pone.0003835

    • Related Report
      2011 Final Research Report
    • Peer Reviewed
  • [Journal Article] Interacting targets of the farnesyl oftransducin γ-subunit2008

    • Author(s)
      Katadae,M., Fukada,Y.
    • Journal Title

      Biochemistry

      Volume: 47 Issue: 32 Pages: 8424-8433

    • DOI

      10.1021/bi800359h

    • Related Report
      2011 Final Research Report
    • Peer Reviewed
  • [Journal Article] (*corresponding authors)Probing pineal-specific gene expression with transgenic zebrafish.Photochem2008

    • Author(s)
      Kojima,D., Dowling*,J.E. & Fukada,Y. *
    • Journal Title

      Photobiol.

      Volume: 84 Issue: 4 Pages: 1011-1015

    • DOI

      10.1111/j.1751-1097.2008.00363.x

    • Related Report
      2011 Final Research Report
    • Peer Reviewed
  • [Journal Article] Differential expression of duplicated VAL-opsin genes in the developing zebrafish2008

    • Author(s)
      Kojima,D., Torii,M., Fukada,Y. & Dowling,J.E.
    • Journal Title

      J. Neurochem.

      Volume: 104 Issue: 5 Pages: 1364-1371

    • DOI

      10.1111/j.1471-4159.2007.05093.x

    • Related Report
      2011 Final Research Report
    • Peer Reviewed
  • [Journal Article]2008

    • Author(s)
      Kon, N., Hirota, T., Kawamoto, T., Kato, Y., Tsubota, T., Fukada, Y.
    • Journal Title

      Nature Cell Biol. 10

      Pages: 1463-1469

    • Related Report
      2009 Self-evaluation Report
  • [Journal Article]2008

    • Author(s)
      Tamai, S., Sanada, K., Fukada, Y.
    • Journal Title

      PLoS One 3

    • Related Report
      2009 Self-evaluation Report
  • [Journal Article] Pobing pineal-specific gene expression with transgenic zebrafish2008

    • Author(s)
      Daisuke Kojima
    • Journal Title

      Photochem 84

      Pages: 1011-1015

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Interacting targets of the farnesyl of transducin γ-subunit2008

    • Author(s)
      Maiko Katadae
    • Journal Title

      Biochemistry 47

      Pages: 8424-8433

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Activation of TGF-β/activin signalling resets the circadian clock through rapid induction of Decl transcripts2008

    • Author(s)
      Naohiro Kon
    • Journal Title

      Nature Cell Biol. 10

      Pages: 1463-1469

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Time-of-day-dependent engancement of adult meurogenesis in hippocampus2008

    • Author(s)
      So-ichi Tamai
    • Journal Title

      PLoS One 3

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Macrophage inhibitory cytokine MIC-l is upregulated by short-wavelength light in cultured normal human dermal fibroblasts2008

    • Author(s)
      Masashi Akiyama
    • Journal Title

      FEBS Lett. 583

      Pages: 933-937

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Differential expression of duplicated VAL-opsin genes in the developing zebrafish2008

    • Author(s)
      Daisuke Kojima
    • Journal Title

      J. Neurochem. 104

      Pages: 1364-1371

    • Related Report
      2007 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Interacting targets of the farnesyl of transducin γ-subunit2008

    • Author(s)
      Maiko Katadae
    • Journal Title

      Biochemistry 104

      Pages: 1364-1371

    • Related Report
      2007 Annual Research Report
    • Peer Reviewed
  • [Journal Article]2008

    • Author(s)
      深田吉孝(分担執筆)
    • Journal Title

      図説 分子病態学 改訂4版の「視覚異常症」の項を分担執筆(中外医学社)

      Pages: 354-359

    • Related Report
      2007 Annual Research Report
  • [Journal Article]2008

    • Author(s)
      深田古孝(分担執筆)
    • Journal Title

      時間生物学事典の「Cry遺伝子」の項を分担執筆(朝倉書店)

      Pages: 202-208

    • Related Report
      2007 Annual Research Report
  • [Journal Article] Two isoforms of chicken melanopsins show blue lightsensitivity2007

    • Author(s)
      Torii,M., Kojima,D., Fukada,Y.
    • Journal Title

      FEBS Lett.

      Volume: 581 Issue: 27 Pages: 5327-5331

    • DOI

      10.1016/j.febslet.2007.10.019

    • Related Report
      2011 Final Research Report
    • Peer Reviewed
  • [Journal Article] (*equal contribution; #corresponding authors) LKB1 regulates neuronal migration and neuronal differentiation in the developing neocortex through centrosomal positioning2007

    • Author(s)
      Asada,N.*, Sanada,K.*# & Fukada,Y.#
    • Journal Title

      J. Neurosci.

      Volume: 27 Issue: 43 Pages: 11769-11775

    • DOI

      10.1523/jneurosci.1938-07.2007

    • Related Report
      2011 Final Research Report
    • Peer Reviewed
  • [Journal Article] Circadian phosphorylation of ATF-2, a potential activator of Period2 gene transcription in the chick pineal gland2007

    • Author(s)
      Shimizu,F. & Fukada,Y.
    • Journal Title

      J. Neurochem.

      Volume: 103 Issue: 5 Pages: 1834-1842

    • DOI

      10.1111/j.1471-4159.2007.04900.x

    • Related Report
      2011 Final Research Report
    • Peer Reviewed
  • [Journal Article] Circadian proteomics of the mouse retina2007

    • Author(s)
      Tsuji,T., Fukada,Y.
    • Journal Title

      Proteomics

      Volume: 7 Issue: 19 Pages: 3500-3508

    • DOI

      10.1002/pmic.200700272

    • Related Report
      2011 Final Research Report
    • Peer Reviewed
  • [Journal Article] Circadian clock gene regulation of steroidogenic acute regulatory protein gene expression in pre-ovulatory ovarian follicles2007

    • Author(s)
      Nobuhiro Nakao
    • Journal Title

      Endocrinol 148

      Pages: 3031-3038

    • Related Report
      2007 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Circadian proteomics of the mouse retina2007

    • Author(s)
      Takahiro Tsuji
    • Journal Title

      Proteomics 7

      Pages: 3500-3507

    • Related Report
      2007 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Circadian phosphorylation of ATF-2, a potential activator of Period2 gene transcription in the chick pineal gland2007

    • Author(s)
      Fumiko Shimizu
    • Journal Title

      J. Neurochem 103

      Pages: 1834-1842

    • Related Report
      2007 Annual Research Report
    • Peer Reviewed
  • [Journal Article] LKB1 regulates neuronal migration and neuronal differentiation in the developing neocortex through centrosomal positioning2007

    • Author(s)
      Naoyuki Asada
    • Journal Title

      J. Neurosci 148

      Pages: 3031-3038

    • Related Report
      2007 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Two isoforms of chicken melanopsins show blue light sensitivity2007

    • Author(s)
      Masaki Torii
    • Journal Title

      FEBS Lett. 27

      Pages: 11769-11775

    • Related Report
      2007 Annual Research Report
    • Peer Reviewed
  • [Journal Article]2007

    • Author(s)
      深田吉孝(分担執筆)
    • Journal Title

      21世紀の動物科学シリーズ:第9巻『動物の感覚とリズム』の「序章:感覚系と生物時計の対比と連関」の項を分担執筆(培風館)

      Pages: 1-5

    • Related Report
      2007 Annual Research Report
  • [Journal Article]2007

    • Author(s)
      岡野俊行(分担執筆)
    • Journal Title

      21世紀の動物科学シリーズ:第9巻『動物の感覚とリズム』の「第6章:概日リズムの分子機構」の項を分担執筆(培風館)

      Pages: 126-147

    • Related Report
      2007 Annual Research Report
  • [Journal Article]2007

    • Author(s)
      深田吉孝(分担執筆)
    • Journal Title

      Clinical Neuroscience, Vol. 25, No. 10, 特集『中枢時計と末梢時計:時計遺伝子研究の最前線』の「概日時計機構の最前線. 」の項を分担執筆(中外医学社)

      Pages: 1090-1093

    • Related Report
      2007 Annual Research Report
  • [Journal Article]2007

    • Author(s)
      深田吉孝(分担執筆)
    • Journal Title

      血管医学、Vol. 8, 特集『循環器系のサーカディアン調節』の「体内時計の分子メカニズム」の項を分担執筆(メディカルレビュー社)

      Pages: 341-348

    • Related Report
      2007 Annual Research Report
  • [Presentation] c-Jun N-Terminal Kinase Regulates the Photic Response of the Mammalian Circadian Clock2012

    • Author(s)
      Hikari Yoshitane
    • Organizer
      SRBR 2012 Meeting
    • Place of Presentation
      Destin, USA
    • Year and Date
      2012-05-20
    • Related Report
      2011 Final Research Report
  • [Presentation] 視覚の光受容細胞における感度調節とノイズ低減の分子機構2011

    • Author(s)
      小島大輔
    • Organizer
      日本動物学会第82回旭川大会2011
    • Place of Presentation
      旭川市大雪クリスタルホール, 旭川
    • Year and Date
      2011-09-21
    • Related Report
      2011 Final Research Report
  • [Presentation] Posttranslational light activation of sterol regulatory element-binding protein is important for phase-delay of the chick pineal clock2011

    • Author(s)
      Yoshitaka Fukada
    • Organizer
      XII Congress of the EBRS
    • Place of Presentation
      Oxford, UK
    • Year and Date
      2011-08-26
    • Related Report
      2011 Final Research Report
  • [Presentation] 新しい紫外光受容体の発現細胞の同定2011

    • Author(s)
      森卓
    • Organizer
      時間生物フォーラム東京2011
    • Place of Presentation
      早稲田大学(東京都)
    • Year and Date
      2011-02-12
    • Related Report
      2010 Annual Research Report
  • [Presentation] 多様なE-boxに依存する概日性転写リズムの制御2011

    • Author(s)
      Ngoc-Hien Du
    • Organizer
      時間生物フォーラム東京2011
    • Place of Presentation
      早稲田大学(東京都)
    • Year and Date
      2011-02-12
    • Related Report
      2010 Annual Research Report
  • [Presentation] UV-sensitive non-visual photopigment in mammals.2011

    • Author(s)
      Suguru Mori
    • Organizer
      第8回国際比較生理生化学会議
    • Place of Presentation
      名古屋国際会議場(名古屋市)
    • Related Report
      2011 Annual Research Report
  • [Presentation] UV-sensitive non-visual opsin in mammals.2011

    • Author(s)
      Daisuke Kojima
    • Organizer
      FASEB SRC Biology and Chemistry of Vision
    • Place of Presentation
      米国アリゾナ州ケアフリー
    • Related Report
      2011 Annual Research Report
  • [Presentation] Functional regulation of bHLH-PAS transcription factors CLOCK and BMAL1 in mammalian circadian clockwork2010

    • Author(s)
      吉種光
    • Organizer
      第33回日本分子生物学会年会, 第83回日本生化学会大会合同大会
    • Place of Presentation
      神戸国際展示場(神戸市)
    • Year and Date
      2010-12-10
    • Related Report
      2010 Annual Research Report
  • [Presentation] マウス脳におけるプロテインキナーゼの発現と細胞内局在の日内変動2010

    • Author(s)
      杉山康憲
    • Organizer
      第33回日本分子生物学会年会, 第83回日本生化学会大会合同大会
    • Place of Presentation
      神戸国際展示場(神戸市)
    • Year and Date
      2010-12-07
    • Related Report
      2010 Annual Research Report
  • [Presentation] E-boxの周辺配列が転写活性化の制御に寄与する可能性2010

    • Author(s)
      Ngoc-Hien Du
    • Organizer
      第17回日本時間生物学会学術大会
    • Place of Presentation
      早稲田大学国際会議場(東京都)
    • Year and Date
      2010-11-21
    • Related Report
      2010 Annual Research Report
  • [Presentation] CRY2のリン酸化依存的分解による時計遺伝子と時計タンパク質の発現調節2010

    • Author(s)
      平野有紗
    • Organizer
      第17回日本時間生物学会学術大会
    • Place of Presentation
      早稲田大学国際会議場(東京都)
    • Year and Date
      2010-11-21
    • Related Report
      2010 Annual Research Report
  • [Presentation] CLOCKのリン酸化状態を特異的に識別するプローブ抗体の作製2010

    • Author(s)
      今村聖路
    • Organizer
      第17回日本時間生物学会学術大会
    • Place of Presentation
      早稲田大学国際会議場(東京都)
    • Year and Date
      2010-11-21
    • Related Report
      2010 Annual Research Report
  • [Presentation] マウス網膜高次ニューロンに存在する近紫外光感受性の新規光受容体2010

    • Author(s)
      鳥居雅樹
    • Organizer
      第17回日本時間生物学会学術大会
    • Place of Presentation
      早稲田大学国際会議場(東京都)
    • Year and Date
      2010-11-21
    • Related Report
      2010 Annual Research Report
  • [Presentation] 細胞時計の新しい位相リセットシグナリングの解析2010

    • Author(s)
      吉種光
    • Organizer
      第17回日本時間生物学会学術大会
    • Place of Presentation
      早稲田大学国際会議場(東京都)
    • Year and Date
      2010-11-21
    • Related Report
      2010 Annual Research Report
  • [Presentation] 新規時計関連キナーゼDYRK1Aによる概日時計の周期制御2010

    • Author(s)
      倉林伸博
    • Organizer
      第17回日本時間生物学会学術大会
    • Place of Presentation
      早稲田大学国際会議場(東京都)
    • Year and Date
      2010-11-20
    • Related Report
      2010 Annual Research Report
  • [Presentation] ゼブラフィッシュの体色変化を制御する光受容体の探索:発生工学的手法を用いた解析2010

    • Author(s)
      小島大輔
    • Organizer
      日本動物学会第81回東京大会
    • Place of Presentation
      東京大学教養部(東京都)
    • Year and Date
      2010-09-24
    • Related Report
      2010 Annual Research Report
  • [Presentation] 網膜に発現するオプシン様タンパク質の機能解析2010

    • Author(s)
      森卓
    • Organizer
      日本動物学会第81回東京大会
    • Place of Presentation
      東京大学教養部(東京都)
    • Year and Date
      2010-09-23
    • Related Report
      2010 Annual Research Report
  • [Presentation] ゼブラフィッシュ桿体視細胞の高い光感度には低活性型の光受容体キナーゼが寄与する2010

    • Author(s)
      白木知也
    • Organizer
      日本動物学会第81回東京大会
    • Place of Presentation
      東京大学教養部(東京都)
    • Year and Date
      2010-09-23
    • Related Report
      2010 Annual Research Report
  • [Presentation] ゼブラフィッシュ視細胞の光感度調節におけるオプシンキナーゼ活性の重要性2010

    • Author(s)
      小島大輔
    • Organizer
      視覚科学フォーラム第14回研究会
    • Place of Presentation
      筑波大学(つくば市)
    • Year and Date
      2010-08-26
    • Related Report
      2010 Annual Research Report
  • [Presentation] 松果体時計の光位相制御シグナリング2010

    • Author(s)
      深田吉孝
    • Organizer
      16回光生物学協会年会
    • Place of Presentation
      大阪大学(大阪市)
    • Year and Date
      2010-08-10
    • Related Report
      2010 Annual Research Report
  • [Presentation] 自律的に時を刻む生物時計の分子制御2010

    • Author(s)
      深田吉孝
    • Organizer
      ATI財団法人新世代研究所「時を計る」研究会
    • Place of Presentation
      新世代研究所(東京都)
    • Year and Date
      2010-07-29
    • Related Report
      2010 Annual Research Report
  • [Presentation] 視細胞におけるG蛋白質γサブユニットのファルネシル化の生理的役割2010

    • Author(s)
      小島大輔
    • Organizer
      日本比較生理生化学会第32回大会
    • Place of Presentation
      九州産業大学(福岡市)
    • Year and Date
      2010-07-19
    • Related Report
      2010 Annual Research Report
  • [Presentation] ゼブラフィッシュ錐体視細胞の光応答特性を制御する光受容体キナーゼ2010

    • Author(s)
      白木知也
    • Organizer
      日本比較生理生化学会第32回大会
    • Place of Presentation
      九州産業大学(福岡市)
    • Year and Date
      2010-07-17
    • Related Report
      2010 Annual Research Report
  • [Presentation] Light induced body color change in the transgenic zebrafish conditionally lacking retinal rod and cone photoreceptors2010

    • Author(s)
      Daisuke Kojima
    • Organizer
      The 9th International Conference on Zebrafish Development & Genetics
    • Place of Presentation
      The University of Wisconsin(USA
    • Year and Date
      2010-06-18
    • Related Report
      2010 Annual Research Report
  • [Presentation] 概日リズムと長期記憶形成の機能連関におけるSCOPの役割2010

    • Author(s)
      清水貴美子
    • Organizer
      第10回分子生物学会春季シンポジウム
    • Place of Presentation
      ホテル松島大観荘(宮城県)
    • Year and Date
      2010-06-07
    • Related Report
      2010 Annual Research Report
  • [Presentation] Phosphorylation of CLOCK/NPA52-BMAL1 complex in suppression of E-box-dependent transcription2010

    • Author(s)
      Hikari Yoshitane
    • Organizer
      12th Meeting Society for Research on Biological Rhythms
    • Place of Presentation
      Sandestin Golf and Beach Resort Destin(USA)
    • Year and Date
      2010-05-25
    • Related Report
      2010 Annual Research Report
  • [Presentation] In vivo analysis of phosphrylation-dependent degradation of mCRY22010

    • Author(s)
      Arisa Hirano
    • Organizer
      12th Meeting Society for Research on Biological rhythms
    • Place of Presentation
      Sandestin Golf and BeachResort Destin(USA)
    • Year and Date
      2010-05-25
    • Related Report
      2010 Annual Research Report
  • [Presentation] ゼブラフィッシュの体色変化を制御する光センサーの探索2010

    • Author(s)
      小島大輔
    • Organizer
      分子研研究会
    • Place of Presentation
      分子科学研究所
    • Year and Date
      2010-03-24
    • Related Report
      2009 Annual Research Report
  • [Presentation] Mutational analysis of in vivo phosphorylation sites of CLOCK protein2009

    • Author(s)
      Ngoc-Hien Du
    • Organizer
      第32回日本分子生物学会年会
    • Place of Presentation
      パシフィコ横浜
    • Year and Date
      2009-12-12
    • Related Report
      2009 Annual Research Report
  • [Presentation] ゼブラフィシュ桿体と錐体の光応答特性におけるGRK1とGRK7の役割の分子生理学的解析2009

    • Author(s)
      白木知也
    • Organizer
      第32回日本分子生物学会年会
    • Place of Presentation
      パシフィコ横浜
    • Year and Date
      2009-12-12
    • Related Report
      2009 Annual Research Report
  • [Presentation] TGF-ss/activin signaling regulates circadian clock through bHLH transcription factor DEC12009

    • Author(s)
      金尚宏
    • Organizer
      第32回日本分子生物学会年会
    • Place of Presentation
      パシフィコ横浜, 横浜
    • Year and Date
      2009-12-11
    • Related Report
      2011 Final Research Report
  • [Presentation] TGF-β/activin signaling regulates circadian clock through bHLH transcription factor DEC12009

    • Author(s)
      金尚宏
    • Organizer
      第32回日本分子生物学会年会
    • Place of Presentation
      パシフィコ横浜
    • Year and Date
      2009-12-11
    • Related Report
      2009 Annual Research Report
  • [Presentation] Circadian timekeeping mechanism with temporally regulated protein phosphorylation2009

    • Author(s)
      深田吉孝
    • Organizer
      第32回日本分子生物学会年会
    • Place of Presentation
      パシフィコ横浜
    • Year and Date
      2009-12-11
    • Related Report
      2009 Annual Research Report
  • [Presentation] 培養細胞におけるSCOPノックダウンを用いた時計発振機構へのアプローチ.2009

    • Author(s)
      小林大起
    • Organizer
      第32回日本分子生物学会年会
    • Place of Presentation
      パシフィコ横浜
    • Year and Date
      2009-12-09
    • Related Report
      2009 Annual Research Report
  • [Presentation] Ser38/Ser42 phosphorylation of CLOCK critical for its DNA-binding and suppression of E-box-dependent transcription2009

    • Author(s)
      吉種光
    • Organizer
      第6回アジア睡眠学会 日本睡眠学会第34回定期学術集会 第16回日本時間生物学会学術大会合同大会
    • Place of Presentation
      大阪国際会議場
    • Year and Date
      2009-10-27
    • Related Report
      2009 Annual Research Report
  • [Presentation] C末端領域のリン酸化によるマウスCRY2タンパク質の分解制御2009

    • Author(s)
      倉林伸博
    • Organizer
      第6回アジア睡眠学会 日本睡眠学会第34回定期学術集会 第16回日本時間生物学会学術大会合同大会
    • Place of Presentation
      大阪国際会議場
    • Year and Date
      2009-10-27
    • Related Report
      2009 Annual Research Report
  • [Presentation] マウスCRY2におけるC末端領域リン酸化の生理的役割2009

    • Author(s)
      平野有沙
    • Organizer
      第6回アジア睡眠学会 日本睡眠学会第34回定期学術集会 第16回日本時間生物学会学術大会合同大会
    • Place of Presentation
      大阪国際会議場
    • Year and Date
      2009-10-27
    • Related Report
      2009 Annual Research Report
  • [Presentation] Multiple mechanisms for resetting of the cellular clock2009

    • Author(s)
      深田吉孝
    • Organizer
      第6回アジア睡眠学会 日本睡眠学会第34回定期学術集会 第16回日本時間生物学会学術大会合同大会
    • Place of Presentation
      大阪市中央公会堂
    • Year and Date
      2009-10-25
    • Related Report
      2009 Annual Research Report
  • [Presentation] 末梢時計の位相制御:Per遺伝子の誘導を伴わない機構2009

    • Author(s)
      深田吉孝
    • Organizer
      第34回日本比較内分沁学会大会 日本比較生理生化学会第31回大会 合同大会
    • Place of Presentation
      千里ライフサイエンスセンター
    • Year and Date
      2009-10-24
    • Related Report
      2009 Annual Research Report
  • [Presentation] Rhythmic phosphorylation of CLOCK and BMAL1 at different phases of circadian clock2009

    • Author(s)
      吉種光
    • Organizer
      第82回日本生化学会大会
    • Place of Presentation
      神戸国際会議場
    • Year and Date
      2009-10-24
    • Related Report
      2009 Annual Research Report
  • [Presentation] Degradation mechanism of CRY2 dependent on its circadian-regulated phosphorylation in mammals2009

    • Author(s)
      倉林伸博
    • Organizer
      第82回日本生化学会大会
    • Place of Presentation
      神戸国際会議場
    • Year and Date
      2009-10-23
    • Related Report
      2009 Annual Research Report
  • [Presentation] 視細胞の欠損を誘導できる遺伝子組換えゼブラフィッシュの体色変化2009

    • Author(s)
      小島大輔
    • Organizer
      第34回日本比較内分沁学会大会 日本比較生理生化学会第31回大会 合同大会
    • Place of Presentation
      千里ライフサイエンスセンター
    • Year and Date
      2009-10-23
    • Related Report
      2009 Annual Research Report
  • [Presentation] ニワトリ松果体で光誘導される遺伝子群の同定とその生理的役割の解析2009

    • Author(s)
      飯塚倫子
    • Organizer
      第34回日本比較内分沁学会大会 日本比較生理生化学会第31回大会 合同大会
    • Place of Presentation
      千里ライフサイエンスセンター
    • Year and Date
      2009-10-23
    • Related Report
      2009 Annual Research Report
  • [Presentation] 視細胞をコンディショナルに欠損する遺伝子組換えゼブラフィッシュの体色変化2009

    • Author(s)
      松本翔
    • Organizer
      日本動物学会第80回大会
    • Place of Presentation
      静岡コンベンションアーツセンター グランシップ
    • Year and Date
      2009-09-19
    • Related Report
      2009 Annual Research Report
  • [Presentation] ゼブラフィッシュ桿体の光応答特性を調節するオプシンキナーゼGRK2009

    • Author(s)
      白木知也
    • Organizer
      日本動物学会第80回大会
    • Place of Presentation
      静岡コンベンションアーツセンター グランシップ
    • Year and Date
      2009-09-19
    • Related Report
      2009 Annual Research Report
  • [Presentation] 視細胞の光シグナリングにおけるG蛋白質の特徴的な構造の重要性2009

    • Author(s)
      小島大輔
    • Organizer
      第13回視覚科学フォーラム研究会
    • Place of Presentation
      鹿児島大学
    • Year and Date
      2009-09-03
    • Related Report
      2009 Annual Research Report
  • [Presentation] CLOCK phosphorylation plays an active role in the suppression phase of E-box-dependent transcripti on2009

    • Author(s)
      深田吉孝
    • Organizer
      生物リズムに関する国際シンポジウム
    • Place of Presentation
      札幌京王プラザホテル
    • Year and Date
      2009-08-03
    • Related Report
      2009 Annual Research Report
  • [Presentation] Close inspection of real-time bioluminescence rhythms revealeda new resetting mechanism of the fibroblast clock2009

    • Author(s)
      深田吉孝
    • Organizer
      第36回国際生理学会世界大会
    • Place of Presentation
      国立京都国際会館
    • Year and Date
      2009-08-01
    • Related Report
      2009 Annual Research Report
  • [Presentation] Altered Photoresponses of Zebrafish Rods Expressing a Cone-Specific G-Protein-Coupled Receptor Kinase, GRK72009

    • Author(s)
      Tomoya Shiraki
    • Organizer
      2009 FASEB Summer Research Conferences Biology and Chemistry of Vision
    • Place of Presentation
      Snowmass Village, USA
    • Year and Date
      2009-06-16
    • Related Report
      2011 Final Research Report
  • [Presentation] 生体リズムを制御する分子時計と同調機構2009

    • Author(s)
      深田吉孝
    • Organizer
      第21回日本アレルギー学会春季臨床大会
    • Place of Presentation
      長良川国際会議場
    • Year and Date
      2009-06-04
    • Related Report
      2009 Annual Research Report
  • [Presentation] 光刺激に対してニワトリ松果体が示す生理応答の解析2009

    • Author(s)
      飯塚 倫子
    • Organizer
      日本動物学会関東支部第61回大会
    • Place of Presentation
      さいたま(埼玉大学)
    • Year and Date
      2009-03-20
    • Related Report
      2008 Annual Research Report
  • [Presentation] マウス視交叉上核におけるSCOPタンパク質量の光制御とその役割2008

    • Author(s)
      清水 貴美子
    • Organizer
      BMB2008(第31回日本分子生物学会年会・第81匠は本生化学会大会合同大会)
    • Place of Presentation
      神戸(神戸ポートアイランド)
    • Year and Date
      2008-12-12
    • Related Report
      2008 Annual Research Report
  • [Presentation] CLOCK phosphorylation plays a key for the suppression of its transactivation in circadian clockwork2008

    • Author(s)
      hikari Yoshitane
    • Organizer
      BMB2008(第31回日本分子生物学会年会・第81匠は本生化学会大会合同大会)
    • Place of Presentation
      神戸(神戸ポートアイランド)
    • Year and Date
      2008-12-12
    • Related Report
      2008 Annual Research Report
  • [Presentation] 細胞外pHのアルカリ性化はDec1遺伝子の誘導を介して概日時計の位相をリセットする2008

    • Author(s)
      金 尚宏
    • Organizer
      BMB2008(第31回日本分子生物学会年会・第81匠は本生化学会大会合同大会)
    • Place of Presentation
      神戸(神戸ポートアイランド)
    • Year and Date
      2008-12-12
    • Related Report
      2008 Annual Research Report
  • [Presentation] Purification of recombinant chicken melanopsin retaining blue light sensitivity2008

    • Author(s)
      鳥居 雅樹
    • Organizer
      BMB2008(第31回日本分子生物学会年会・第81匠は本生化学会大会合同大会)
    • Place of Presentation
      神戸(神戸ポートアイランド)
    • Year and Date
      2008-12-10
    • Related Report
      2008 Annual Research Report
  • [Presentation] TGF-β/activinシグナルによるDec1依存型の新規時計リセット機構2008

    • Author(s)
      金 尚宏
    • Organizer
      第15回日本時間生物学会学術大会岡山
    • Place of Presentation
      岡山大学創立50周年記念館
    • Year and Date
      2008-11-09
    • Related Report
      2008 Annual Research Report
  • [Presentation] E-boxを介した転写抑制において重要な役割を果たすCLOCKの過リン酸化2008

    • Author(s)
      吉種 光
    • Organizer
      第15回日本時間生物学会学術大会岡山
    • Place of Presentation
      岡山大学創立50周年記念館
    • Year and Date
      2008-11-09
    • Related Report
      2008 Annual Research Report
  • [Presentation] 概日時計が長期記憶形成を制御する神経システムへの分子的アプローチ2008

    • Author(s)
      小林洋大
    • Organizer
      第15回日本時間生物学会学術大会岡山
    • Place of Presentation
      岡山大学創立50周年記念館
    • Year and Date
      2008-11-08
    • Related Report
      2008 Annual Research Report
  • [Presentation] マウスCRY2のSer557リン酸化を担うタンパク質キナーゼの探索2008

    • Author(s)
      倉林 伸博
    • Organizer
      第15回日本時間生物学会学術大会岡山
    • Place of Presentation
      岡山大学創立50周年記念館
    • Year and Date
      2008-11-08
    • Related Report
      2008 Annual Research Report
  • [Presentation] マウスCRY2におけるC末端領域のリン酸化が概日リズム形成に果す役割2008

    • Author(s)
      平野 有沙
    • Organizer
      第15回日本時間生物学会学術大会岡山
    • Place of Presentation
      岡山大学創立50周年記念館
    • Year and Date
      2008-11-08
    • Related Report
      2008 Annual Research Report
  • [Presentation] ファルネシル欠失型G蛋白質γサブユニットを発現する網膜視細胞の光応答解析2008

    • Author(s)
      小島 大輔
    • Organizer
      東京大学生命科学研究ネットワークシンポジウム2008
    • Place of Presentation
      東京(東京大学工学部2号館)
    • Year and Date
      2008-09-23
    • Related Report
      2008 Annual Research Report
  • [Presentation] 視細胞をコンディショナルに欠損する遺伝子組換えゼブラフィッシュ2008

    • Author(s)
      小島 大輔
    • Organizer
      日本動物学会第79回大会
    • Place of Presentation
      福岡(福岡大学七隈キャンパス)
    • Year and Date
      2008-09-06
    • Related Report
      2008 Annual Research Report
  • [Presentation] 錐体オブシンキナーゼGRK7を異所的に発現させたゼブラフィッシュ桿体の光応答2008

    • Author(s)
      白木 知也
    • Organizer
      日本動物学会第79回大会
    • Place of Presentation
      福岡(福岡大学七隈キャンパス)
    • Year and Date
      2008-09-06
    • Related Report
      2008 Annual Research Report
  • [Presentation] ニワトリ松果体におけるコレステロール合成系酵素群の遺伝子発現解析2008

    • Author(s)
      飯塚 倫子
    • Organizer
      日本比較生理生化学会第30回大会
    • Place of Presentation
      札幌(北海道大学理学部 5号館)
    • Year and Date
      2008-07-19
    • Related Report
      2008 Annual Research Report
  • [Presentation] PIPE-dependent pineral gene experssion with transgenic Zevrafish2008

    • Author(s)
      Daisuke Kojima
    • Organizer
      8th Interntonal Meeting on Zebrafish Development and Genetics
    • Place of Presentation
      Madison(Unfversity of Wisconsin Madison Campus)
    • Year and Date
      2008-06-27
    • Related Report
      2008 Annual Research Report
  • [Presentation] Molecular and in vivo functional studies on sequential phosphoylarion of mCRY22008

    • Author(s)
      Nobuhiro Kurabayashi
    • Organizer
      Iith Meeting Society for Research on Rhythms
    • Place of Presentation
      Flotifa(Sendestin Golf and Beach Resort)
    • Year and Date
      2008-05-18
    • Related Report
      2008 Annual Research Report
  • [Presentation] 視細胞をコンディショナルに欠損するゼブラフィッシュ系統の樹立〜体色変化を制御する光受容システムの解析ツールの開発〜2008

    • Author(s)
      松本翔
    • Organizer
      日本動物学会関東支部第60回大会
    • Place of Presentation
      東京(東京大学総合文化研究科)
    • Year and Date
      2008-03-22
    • Related Report
      2007 Annual Research Report
  • [Presentation] ゼブラフィッシュ松果体の特異性を規定する転写因子の同定2007

    • Author(s)
      真野弘明
    • Organizer
      第30回日分子生物学会年会,第80回日本生化学会大会合同大会
    • Place of Presentation
      パシフィコ横浜, 横浜
    • Year and Date
      2007-12-14
    • Related Report
      2011 Final Research Report
  • [Presentation] ゼブラフィッシュ松果体の特異性を規定する転写因子の同定2007

    • Author(s)
      真野弘明
    • Organizer
      第30回日本分子生物学会年会, 第80回日本生化学会大会合同大会
    • Place of Presentation
      横浜(パシフィコ横浜)
    • Year and Date
      2007-12-14
    • Related Report
      2007 Annual Research Report
  • [Presentation] 大脳新皮質の発生過程でLKB1は神経細胞移動と文化を制御する2007

    • Author(s)
      浅田直之
    • Organizer
      第30回日本分子生物学会年会, 第80回日本生化学会大会合同大会
    • Place of Presentation
      横浜(パシフィコ横浜)
    • Year and Date
      2007-12-14
    • Related Report
      2007 Annual Research Report
  • [Presentation] ニワトリメラノプシンの吸収スペクトル2007

    • Author(s)
      小島大輔
    • Organizer
      第30回日本分子生物学会年会, 第80回日本生化学会大会合同大会
    • Place of Presentation
      横浜(パシフィコ横浜)
    • Year and Date
      2007-12-14
    • Related Report
      2007 Annual Research Report
  • [Presentation] 概日リズムのリアルタイムモニター系を用いた時計タンパク質キナーゼの解析2007

    • Author(s)
      金尚宏
    • Organizer
      第30回日本分子生物学会年会, 第80回日本生化学会大会合同大会
    • Place of Presentation
      横浜(パシフィコ横浜)
    • Year and Date
      2007-12-11
    • Related Report
      2007 Annual Research Report
  • [Presentation] Phosphorylation of CLOCK and BMAL1 in circadian oscillation systems2007

    • Author(s)
      Hikari Yoshitane
    • Organizer
      第30回日本分子生物学会年会, 第80回日本生化学会大会合同大会
    • Place of Presentation
      横浜(パシフィコ横浜)
    • Year and Date
      2007-12-11
    • Related Report
      2007 Annual Research Report
  • [Presentation] 海馬の神経新生部位における神経幹細胞の分裂の日内制御2007

    • Author(s)
      玉井総一
    • Organizer
      第30回日本分子生物学会年会, 第80回日本生化学会大会合同大会
    • Place of Presentation
      横浜(パシフィコ横浜)
    • Year and Date
      2007-12-11
    • Related Report
      2007 Annual Research Report
  • [Presentation] Functional expression of chicken melanopsins2007

    • Author(s)
      Masaki Torii
    • Organizer
      第30回日本分子生物学会年会, 第80回日本生化学会大会合同大会
    • Place of Presentation
      横浜(パシフィコ横浜)
    • Year and Date
      2007-12-11
    • Related Report
      2007 Annual Research Report
  • [Presentation] Proteolytic Degradation of SCOP/PHLPP in the Hippocampus Contributes to Activation of ERK/MAPK and Memory Formation2007

    • Author(s)
      Shimizu Kimiko
    • Organizer
      第30回日本分子生物学会年会, 第80回日本生化学会大会合同大会
    • Place of Presentation
      横浜(パシフィコ横浜)
    • Year and Date
      2007-12-11
    • Related Report
      2007 Annual Research Report
  • [Presentation] Molecular basis for circadian rhythm disorder in Clock mutant mice2007

    • Author(s)
      Hikari Yoshitane
    • Organizer
      日本睡眠学会第32回定期学術集会 第14回日本時間生物学会学術大会合同大会
    • Place of Presentation
      東京(京王プラザホテル)
    • Year and Date
      2007-11-07
    • Related Report
      2007 Annual Research Report
  • [Presentation] 細胞外pHの変化は概日時計の位相をリセットする2007

    • Author(s)
      金尚宏
    • Organizer
      日本睡眠学会第32回定期学術集会 第14回日本時間生物学会学術大会合同大会
    • Place of Presentation
      東京(京王プラザホテル)
    • Year and Date
      2007-11-07
    • Related Report
      2007 Annual Research Report
  • [Presentation] 明期延長に伴う光位相シフトにおけるmE4BP4の分子的応答2007

    • Author(s)
      景山伯春
    • Organizer
      日本睡眠学会第32回定期学術集会 第14回日本時間生物学会学術大会合同大会
    • Place of Presentation
      東京(京王プラザホテル)
    • Year and Date
      2007-11-07
    • Related Report
      2007 Annual Research Report
  • [Presentation] Molecular regulation of the chick pineal clockwork2007

    • Author(s)
      Yoshitaka Fukada
    • Organizer
      2^<nd>nd World Congress of Chronobiology
    • Place of Presentation
      東京(京王プラザホテル)
    • Year and Date
      2007-11-06
    • Related Report
      2007 Annual Research Report
  • [Presentation] G11-mediated pineal phototransduction for entrainment of the pineal clock2007

    • Author(s)
      Yoshitaka Fukada
    • Organizer
      7th International Congress of Comparative Physiology and Biochemistry
    • Place of Presentation
      Brazil(Salvador, Bahia)
    • Year and Date
      2007-08-16
    • Related Report
      2007 Annual Research Report
  • [Presentation] Proteolytic Degradation of SCOP in the Hippocampus Contributes to Activation of ERK/MAPK and memory Formation2007

    • Author(s)
      Shimizu Kimiko
    • Organizer
      Neuro 2007(第30回神経科学大会・第50回神経化学学会大会・第17回神経回路学会大会合同大会)
    • Place of Presentation
      横浜(パシフイコ横浜)
    • Year and Date
      2007-08-16
    • Related Report
      2007 Annual Research Report
  • [Presentation] ゼブラフィッシュ眼球に発現する非視覚型オプシン遺伝子群の同定2007

    • Author(s)
      白木知也
    • Organizer
      日本動物学会第78回弘前大会
    • Place of Presentation
      弘前(弘前大学文京町キャンパス)
    • Year and Date
      2007-08-16
    • Related Report
      2007 Annual Research Report
  • [Presentation] ニワトリ松果体の概日時計機構における位相制御と新しい出力候補物質2007

    • Author(s)
      深田吉孝
    • Organizer
      第29回日本比較生理生化学会シンポジウム
    • Place of Presentation
      岡山(岡山大学創立五十周年記念館)
    • Year and Date
      2007-07-06
    • Related Report
      2007 Annual Research Report
  • [Presentation] Farnesylation of retinal transducin plays a role far beyond photo-transduction2007

    • Author(s)
      Yoshitaka Fukada
    • Organizer
      FASEB Summer Research Conferences Biology and Chemistry of Vision
    • Place of Presentation
      Colorado(Snowmass Village)
    • Year and Date
      2007-06-18
    • Related Report
      2007 Annual Research Report
  • [Presentation] Differential expression of duplicated VAL-opsin genes in developing zebrafish2007

    • Author(s)
      Daisuke Kojima
    • Organizer
      FASEB Summer Research Conferences Biology and Chemistry of Vision
    • Place of Presentation
      Colorado(Snowmass Village)
    • Year and Date
      2007-06-18
    • Related Report
      2007 Annual Research Report
  • [Presentation] Antiphasic phosphorylation of clock and BMAL12007

    • Author(s)
      Hikari Yoshitane
    • Organizer
      72nd Cold Spring Harbor Symposium on Quantitative Biology Clocks & Rhythms
    • Place of Presentation
      New York (Cold Spring Harbor laboratory)
    • Year and Date
      2007-06-01
    • Related Report
      2007 Annual Research Report
  • [Presentation] Molecular studies on Phosphorylation of CRYPTOCHROME2 at SER5572007

    • Author(s)
      Nobuhiro Kurabayashi
    • Organizer
      72nd Cold Spring Harbor Symposium on Quantitative Biology Clocks & Rhythms
    • Place of Presentation
      New York (Cold Spring Harbor laboratory)
    • Year and Date
      2007-05-31
    • Related Report
      2007 Annual Research Report
  • [Presentation] Pharmacological analysis of clock protein kinases participatine in molecular oscillation in RAT-1 fibroblasts2007

    • Author(s)
      Naohiro Kon
    • Organizer
      72nd Cold Spring Harbor Symposium on Quantitative Biology Clocks & Rhythms
    • Place of Presentation
      New York (Cold Spring Harbor laboratory)
    • Year and Date
      2007-05-30
    • Related Report
      2007 Annual Research Report
  • [Presentation] Non-visual photoreception in vertebrates.

    • Author(s)
      Daisuke Kojima
    • Organizer
      第8回国際比較生理生化学会議
    • Place of Presentation
      名古屋国際会議場(名古屋市)
    • Related Report
      2011 Annual Research Report
    • Invited
  • [Presentation] サーカディアンリズムの光制御の分子シグナリング

    • Author(s)
      深田 吉孝
    • Organizer
      大阪大学生命機能研究科研究交流会
    • Place of Presentation
      大阪大学生命機能研究科(吹田市)
    • Related Report
      2011 Annual Research Report
    • Invited
  • [Presentation] Approach for photic entrainment mechanisms of circadian clock via SCOP signaling.

    • Author(s)
      Simizu Kimiko
    • Organizer
      8th IBRO World Congress of Neuroscience
    • Place of Presentation
      伊国フローレンス
    • Related Report
      2011 Annual Research Report
  • [Presentation] UV-sensitive Opsin Expressed in Mammalian Non-visual Cells.

    • Author(s)
      Masaki Torii
    • Organizer
      第5回アジア・オセアニア光生物学会議
    • Place of Presentation
      奈良県新公会堂(奈良市)
    • Related Report
      2011 Annual Research Report
  • [Presentation] Contribution of non-visual photoreceptor to thelight-induced body color change in developing Zebrafish.

    • Author(s)
      Tomoya Shiraki
    • Organizer
      第5回アジア・オセアニア光生物学会議
    • Place of Presentation
      奈良県新公会堂(奈良市)
    • Related Report
      2011 Annual Research Report
  • [Presentation] 物体認識記憶の概日制御機構に関わる分子メカニズム.

    • Author(s)
      清水 貴美子
    • Organizer
      第34回日本神経科学大会
    • Place of Presentation
      パシフィコ横浜(横浜市)
    • Related Report
      2011 Annual Research Report
  • [Presentation] 視覚の光受容細胞における感度調節とノイズ低減の分子機構.

    • Author(s)
      小島 大輔
    • Organizer
      日本動物学会第82回旭川大会
    • Place of Presentation
      旭川市大雪クリスタルホール(旭川市)
    • Related Report
      2011 Annual Research Report
  • [Presentation] ニワトリ松果体の新しい光シグナリングと転写活性化.

    • Author(s)
      深田 吉孝
    • Organizer
      日本動物学会第82回旭川大会
    • Place of Presentation
      旭川市大雪クリスタルホール(旭川市)
    • Related Report
      2011 Annual Research Report
  • [Presentation] Posttranslational regulation of CLOCK-BMAL1 heterodimer

    • Author(s)
      深田 吉孝
    • Organizer
      名古屋大学野依記念学術交流館
    • Place of Presentation
      名古屋大学野依記念学術交流館(名古屋市)
    • Related Report
      2011 Annual Research Report
    • Invited
  • [Presentation] 酸性ショックによるマウス概日時計の位相制御機構.

    • Author(s)
      佐上 彩
    • Organizer
      第34回日本分子生物学会年会
    • Place of Presentation
      パシフィコ横浜(横浜市)
    • Related Report
      2011 Annual Research Report
  • [Presentation] 転写因子E4BP4を介した新規時計リセット機構の解析.

    • Author(s)
      佐上 彩
    • Organizer
      時間生物フォーラム東京2012
    • Place of Presentation
      東京大学理学部3号館(東京都)
    • Related Report
      2011 Annual Research Report
  • [Presentation] マウス肝臓において時計因子CLOCKがリズミックに結合するDNA領域の探索.

    • Author(s)
      寺嶋 秀騎
    • Organizer
      日本動物学会第64関東支部大会
    • Place of Presentation
      東邦大学習志野キャンパス(習志野市)
    • Related Report
      2011 Annual Research Report
  • [Presentation] マウス扁桃体の概日時計機構による情動制御の検証.

    • Author(s)
      中野 純
    • Organizer
      日本動物学会第64関東支部大会
    • Place of Presentation
      東邦大学習志野キャンパス(習志野市)
    • Related Report
      2011 Annual Research Report
  • [Presentation] c-Jun N-Terminal Kinase Regulates the Photic Response of the Mammalian Circadian Clock.

    • Author(s)
      Hikari Yoshitane
    • Organizer
      SRBR 2012 Meeting
    • Place of Presentation
      米国フロリダ州デスティン
    • Related Report
      2011 Annual Research Report
  • [Presentation] Phosphorylation-Dependent Degradation of CRY2 Regulates Relevant Clock Gene Expression and Generates Normal Oscillation of the Circadian Clock.

    • Author(s)
      Arisa Hirano
    • Organizer
      SRBR 2012 Meeting
    • Place of Presentation
      米国フロリダ州デスティン
    • Related Report
      2011 Annual Research Report
  • [Presentation] サーカディアンリズムと光

    • Author(s)
      深田 吉孝
    • Organizer
      第1回ブルーライト研究会
    • Place of Presentation
      大手町ファーストスクエアカンファレンス(東京都)
    • Related Report
      2011 Annual Research Report
    • Invited
  • [Presentation] 時計タンパク質の翻訳後の修飾制御と生体リズム

    • Author(s)
      深田 吉孝
    • Organizer
      第12回日本蛋白質科学会年会
    • Place of Presentation
      名古屋国際会議場(名古屋市)
    • Related Report
      2011 Annual Research Report
    • Invited
  • [Presentation] 哺乳類におけるUV光受容体OPNSの同定と発現部位の解析

    • Author(s)
      森 卓
    • Organizer
      第12回東京大学生命科学シンポジウム
    • Place of Presentation
      東京大学本郷キャンパス(東京都)
    • Related Report
      2011 Annual Research Report
  • [Book] 『時間生物学』第2章 光同調2012

    • Author(s)
      鳥居 雅樹
    • Publisher
      化学同人
    • Related Report
      2011 Annual Research Report
  • [Book] The Enzymes Vol. 29: Protein Prenylation Part A (Elsevier Inc.)2011

    • Author(s)
      Kassai,K.,& Fukada,Y.
    • Publisher
      Farnesylation versus geranylgeranylation in G-protein-mediated light signaling.
    • Related Report
      2011 Final Research Report
  • [Book] Farnesylation versus geranylgeranylation in G-protein-mediated light signaling(Protein Prenylation, Vol. 29)2011

    • Author(s)
      Hidetoshi Kassai
    • Publisher
      Elsevier Inc. Academic Press
    • Related Report
      2011 Annual Research Report
  • [Book] The Enzymes Vol.292011

    • Author(s)
      Hidetoshi Kassai
    • Publisher
      Elsevier(in press)(発行確定)
    • Related Report
      2010 Annual Research Report
  • [Book] 実験医学増刊号2011

    • Author(s)
      倉林伸博
    • Publisher
      羊土社(掲載確定)
    • Related Report
      2010 Annual Research Report
  • [Book] 感染・炎症・免疫 Vol, 402010

    • Author(s)
      深田吉孝
    • Publisher
      羊土社
    • Related Report
      2010 Annual Research Report
  • [Book] 序章:感覚系と生物時計の対比と連関、21世紀の動物科学シリーズ:第 9 巻『動物の感覚とリズム』七田芳則、 深田吉孝共編2007

    • Author(s)
      深田吉孝
    • Publisher
      培風館
    • Related Report
      2011 Final Research Report
  • [Book] 第6章:概日リズムの分子機構、21 世紀の動物科学シリー ズ:第 9 巻『動物の感覚とリズム』七田芳則、深田吉孝 共編2007

    • Author(s)
      岡野俊行、深田吉孝
    • Publisher
      培風館
    • Related Report
      2011 Final Research Report
  • [Remarks] 主要な原著論文については、研究室ホームページの「研究ハイライト」にて研究内容をわかりやすく解説している。

    • URL

      http://www.biochem.s.u-tokyo.ac.jp/fukada-lab/research-highlights-j.html

    • Related Report
      2011 Final Research Report
  • [Remarks] 研究ハイライト

    • URL

      http://www.biochem.s.u-tokyo.ac.jp/fukada-lab/research-highlights-j.html

    • Related Report
      2011 Annual Research Report
  • [Remarks]

    • URL

      http://www.biochem.s.u-tokyo.ac.jp/fukada-lab/

    • Related Report
      2010 Annual Research Report
  • [Remarks] 研究室ホームページ

    • URL

      http://www.biochem.s.u-tokyo.ac.jp/fukada-lab/

    • Related Report
      2009 Self-evaluation Report
  • [Remarks]

    • URL

      http://www.biochem.s.u-tokyo.ac.jp/fukada-lab/

    • Related Report
      2009 Annual Research Report
  • [Remarks]

    • URL

      http://www.biochem.s.u.-tokyo.ac.jp/fukada-lab/

    • Related Report
      2008 Annual Research Report
  • [Remarks]

    • URL

      http://www.biochem.s.u-tokyo.ac.jp/fukada-lab/

    • Related Report
      2007 Annual Research Report
  • [Patent(Industrial Property Rights)] 間欠駆動機構及びこれを用いた給餌装置2011

    • Inventor(s)
      深田吉孝, 布川莉奈, 種光
    • Industrial Property Rights Holder
      東京大学
    • Filing Date
      2011-03-31
    • Related Report
      2011 Final Research Report

URL: 

Published: 2007-04-01   Modified: 2017-03-31  

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