Implementation of intelligent integrated bio-imaging system
| Project/Area Number |
19206041
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| Research Category |
Grant-in-Aid for Scientific Research (A)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Electron device/Electronic equipment
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| Research Institution | Osaka University |
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Principal Investigator |
YAGI Tetsuya Osaka University, 工学研究科, 教授 (50183976)
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| Co-Investigator(Kenkyū-buntansha) |
OSANAI Makoto 東北大学, 医学系研究科, 准教授 (90286419)
SHIMONOMURA Kazuhiro 立命館大学, 理工学部, 准教授 (80397679)
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| Project Period (FY) |
2007 – 2009
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| Project Status |
Completed (Fiscal Year 2009)
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| Budget Amount *help |
¥46,410,000 (Direct Cost: ¥35,700,000、Indirect Cost: ¥10,710,000)
Fiscal Year 2009: ¥5,980,000 (Direct Cost: ¥4,600,000、Indirect Cost: ¥1,380,000)
Fiscal Year 2008: ¥15,470,000 (Direct Cost: ¥11,900,000、Indirect Cost: ¥3,570,000)
Fiscal Year 2007: ¥24,960,000 (Direct Cost: ¥19,200,000、Indirect Cost: ¥5,760,000)
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| Keywords | バイオイメージング / 集積イメージングデバイス / リアルタイム処理 / カルシウム測光 / フィードバック刺激 / 電気刺激 / レーザー刺激 / イメージセンサー / 光刺激 / 薬物投与 / CMOSイメジャー / バイオアッセイ / 実時間処理 / フィードバック / 神経細胞 / 心筋細胞 |
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| Research Abstract |
We devised an intelligent bio-imaging device (IID) consisting of a charge-coupled device (CCD) chip and Field programmable Gate Array (FPGA) circuits. IID is able to not only capture the bio-images but also calculate the locations and patterns of fluorescent changes in the image. Mounting IID and a multi-electrode stimulation apparatus on the microscope, we developed a prototype of novel bio-assay system with which we can automatically give feedback stimulations on nervous and muscle tissues in real time to study their physiological properties.
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Report
(4 results)
Research Products
(64 results)
