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Evolution of drinking mechanism from aquatic to terrestrial habitat : Exploring its origin using fishes

Research Project

Project/Area Number 19207005
Research Category

Grant-in-Aid for Scientific Research (A)

Allocation TypeSingle-year Grants
Section一般
Research Field Morphology/Structure
Research InstitutionThe University of Tokyo

Principal Investigator

TAKEI Yoshio  The University of Tokyo, 海洋研究所, 教授 (10129249)

Co-Investigator(Kenkyū-buntansha) ANDO Masaaki  広島大学, 総合科学部, 准教授 (10100976)
SAKAMOTO Tatsuya  岡山大学, 自然科学研究科, 准教授 (10294480)
Project Period (FY) 2007 – 2009
Project Status Completed (Fiscal Year 2009)
Budget Amount *help
¥50,570,000 (Direct Cost: ¥38,900,000、Indirect Cost: ¥11,670,000)
Fiscal Year 2009: ¥15,860,000 (Direct Cost: ¥12,200,000、Indirect Cost: ¥3,660,000)
Fiscal Year 2008: ¥14,560,000 (Direct Cost: ¥11,200,000、Indirect Cost: ¥3,360,000)
Fiscal Year 2007: ¥20,150,000 (Direct Cost: ¥15,500,000、Indirect Cost: ¥4,650,000)
Keywords浸透圧調節 / 飲水行動 / ホルモン / 水生動物 / 脳内神経回路 / 浸透圧刺激 / 容量刺激 / ウナギ / アンジオテンシン / アドレノメデュリン / ナトリウム利尿ペプチド / ウロテンシン / グレリン / 血圧調整 / 脳室周囲器官 / 血圧調節 / 循環調節 / 腎作用
Research Abstract

In this study, we found that guanylin, adrenomedullin and relaxin form a family of diversified members in teleost fishes and play important roles in osmoregulation, particularly in seawater adaptation. We also found that natriuretic peptides that suppress drinking and angiotensin that induces drinking act on the area postrema in the medulla oblongata to regulate reflex swallowing in aquatic fishes, which is in contrast to terrestrial animals where they regulate thirst by acting on the forebrain.

Report

(4 results)
  • 2009 Annual Research Report   Final Research Report ( PDF )
  • 2008 Annual Research Report
  • 2007 Annual Research Report
  • Research Products

    (85 results)

All 2010 2009 2008 2007 Other

All Journal Article (37 results) (of which Peer Reviewed: 34 results) Presentation (36 results) Book (10 results) Remarks (2 results)

  • [Journal Article] Centrally administered grelin potently inhibits water intake induced by angiotensin II and hypovolemia in rats2010

    • Author(s)
      Hashimoto, H., et.al.
    • Journal Title

      Journal of Physiological Science s 60

      Pages: 19-25

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Acute salinity challenges in Mozambique and Nile tilapia : Differential responses of plasma prolactin, growth hormone and branchial expression of ion transporters2010

    • Author(s)
      Breves, et.al.
    • Journal Title

      General and Comparataive Endocrinology 167

      Pages: 135-142

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Diversified cardiovascular actions of six homologous natriuretic peptides(ANP, BNP, VNP, CNP1, CNP3 and CNP4)in conscious eels2010

    • Author(s)
      Nobata, S., et al
    • Journal Title

      Americal Journal of Physiology (印刷中)

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Profiling differential gene expression of symbiotic and aposymbiotic corals using a high coverage gene expression profiling(HiCEP)analysis2010

    • Author(s)
      Yuyama, I., et al.
    • Journal Title

      Marine Biotechnology (印刷中)

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Identification of angiotensinogen genes with unique and variable angiotensin sequences in cartilaginous fishes.2009

    • Author(s)
      Watanabe, T., Inoue, K., Takei, Y.
    • Journal Title

      General and Comparataive Endocrinology 161

      Pages: 115-122

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Extracellular calcium-sensing receptor expression in osmoregulatory and endocrine tissues of the tilapia.2009

    • Author(s)
      Loretz, C.A., et.al.
    • Journal Title

      General and Comparataive Endocrinology 161

      Pages: 216-228

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Cyclostome and chondrichthyan adrenomedullins reveal ancestral features of the adrenomedullin family.2009

    • Author(s)
      Wong, M.K.S., et.al.
    • Journal Title

      Comparative Biochemistry and Physiology 154B

      Pages: 317-325

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Hagfish natriuretic peptide changes urine flow rates and vascular tensions in a hagfish2009

    • Author(s)
      Tait, L.W., et.al.
    • Journal Title

      Comparative Biochemistry and Physiology 150C

      Pages: 45-49

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Centrally administered adrenomedullin 5 activates oxytocin-secreting neurons in the hypothalamus with elevation of plasma oxytocin level in rats2009

    • Author(s)
      Otsubo, H., et.al.
    • Journal Title

      Journal of Endocrinology 202

      Pages: 237-247

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article]2009

    • Author(s)
      Takei, Y., Balment, R.J
    • Journal Title

      Fish Physiology, Vol.28 : Fish Neuroendocrinology (Eds.N.Bernier, G.Van Der Kraak, A.P.Farrell and C.J.Brauner.)(Academic Press)

    • Related Report
      2009 Annual Research Report
  • [Journal Article]2009

    • Author(s)
      Takei, Y., et.al.
    • Journal Title

      Molecular and functional evolution of the adrenomedullin family in vertebrates : What do fish studies tell us? In : The Calcitonin Gene-Related Peptide Family : From, Function and Future Perspectives. (Eds.D.L.Hay and I.Dickerson)(Springer Verlag Berlin)

    • Related Report
      2009 Annual Research Report
  • [Journal Article]2009

    • Author(s)
      竹井祥郎
    • Journal Title

      生命と水。「海と生命-海の生命観を求めて」海洋生命のダイナミクス5巻11章(塚本勝巳編)(東海大学出版会)

      Pages: 156-170504

    • Related Report
      2009 Annual Research Report
  • [Journal Article] Central and peripheral cardiovascular actions of adreno-medullin 5, a novel member of the calcitonin gene-related peptide family, in mammals2008

    • Author(s)
      Takei, Y, Hashimoto, H., Inoue, K., Osaki, T., Yoshizawa-Kumagaye, K., Watanabe, T. X., Minamino, N., Ueta, Y.
    • Journal Title

      J. Endocrinol. 197

      Pages: 391-400

    • Related Report
      2009 Final Research Report
    • Peer Reviewed
  • [Journal Article] Exploring novel hormones essential for seawater adaptation in teleost fish2008

    • Author(s)
      Takei, Y.
    • Journal Title

      Gen. Comp. Endocrinol. 157

      Pages: 3-13

    • Related Report
      2009 Final Research Report
    • Peer Reviewed
  • [Journal Article] Potent cardiovascular actions of homologous adrenomedullins in eel2008

    • Author(s)
      Nobata, S. , et. al
    • Journal Title

      American Journal of Physiology 294

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Central and psripheral cardiovascular actions of a adreno-medullin 5, a novel member of the calcitonin gene-related peptide family, in mammals2008

    • Author(s)
      Takei, Y. , et. al
    • Journal Title

      Journal of Endocrinology 197

      Pages: 391-400

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Adrenomedullin 2/intermedin-like immunoreactivit in the hypothalamus and brainstem of rats2008

    • Author(s)
      Hashimoto, H. , et. al
    • Journal Title

      Autonomic Nueroscience 139

      Pages: 46-54

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Exporing novel hormones essential for seawater adaptation in teleost fish2008

    • Author(s)
      Takei, Y.
    • Journal Title

      General and Comparative Endocrinology 157

      Pages: 3-13

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Potent osmoregulatory actions of peripherally and centrally administ ered homologous adrenomedullins in eels2008

    • Author(s)
      Ogoshi, M. , et. al
    • Journal Title

      American Journal of Physiology 295

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Identification of angiotensinogen genes with unique and variable angiotensin sequences in cartilaginous fishes2008

    • Author(s)
      Watanabem T. , et. al
    • Journal Title

      General and Comparative Endocrinology 161

      Pages: 115-122

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Extracellularcalcium-sensing receptor expression in osmoregulatory and endocrni tissues of the tilapia2008

    • Author(s)
      Loretz, C. A. , et. al.
    • Journal Title

      General and Comparative Endocrinology 161

      Pages: 216-228

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Journal Article] 魚類からヒトへ: 2種の新規アドレノメデュリンの発見2008

    • Author(s)
      竹井祥郎
    • Journal Title

      循環器科 64

      Pages: 486-495

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Potent cardiovascular actions of homologous adrenomedullins in eel2008

    • Author(s)
      Nobata, S., et. al.
    • Journal Title

      American Journal of Physiology 294

    • Related Report
      2007 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Central and peripheral cardiovascular actions of adrenomedullin 5,anovel member of the calcitonin gene-related peptide family, in mammals2008

    • Author(s)
      Takei, Y, et. al.
    • Journal Title

      Journal of Endocrinology 197

      Pages: 391-400

    • Related Report
      2007 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Adrenomedullin 2/intermedin-like hnmunoreactivity in the hypothalamus and brainstem of rats2008

    • Author(s)
      Hashmoto, H., et. al.
    • Journal Title

      Autonomic Neuroscience 139

      Pages: 46-54

    • Related Report
      2007 Annual Research Report
    • Peer Reviewed
  • [Journal Article] 'reverse' phylogenetic approach for identification of novel osmoregulatory and cardiovascular hormones invertebrates2007

    • Author(s)
      Takei, Y., Ogoshi, M., Inoue, K. A
    • Journal Title

      Frontiers Neuroendocrinol. 28

      Pages: 143-160

    • Related Report
      2009 Final Research Report
    • Peer Reviewed
  • [Journal Article] In vitro effects of homologous natriurtic peptides on growth hormone and prolactin release in the tiapia, Oreochromis mossambieus2007

    • Author(s)
      Fox, B. K, et. al.
    • Journal Title

      General and Comparative Endocrinology 150

      Pages: 270-277

    • Related Report
      2007 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Centrally and peripherally adlministered ghrei potently inhibits water intake in rats2007

    • Author(s)
      Hashimoto, H., et. al.
    • Journal Title

      Endocrinology 148

      Pages: 1638-1647

    • Related Report
      2007 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Adrenomedullin 2 is a morepotent activator of hypothalamic oxytocin\secreting neurons than adrenomedullin in rats, and its effects are only partially blocked by antagonists for adrenomedullin and calcitonin gene-related peptide receptors2007

    • Author(s)
      Hashimoto, H., et. al.
    • Journal Title

      Peptides 28

      Pages: 1104-1112

    • Related Report
      2007 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Natriuretic peptides in cetaceans:Identification, molecular characterization and changes in plasma concentration after landing2007

    • Author(s)
      Naka, T., et. al.
    • Journal Title

      Zoological Science 24

      Pages: 577-587

    • Related Report
      2007 Annual Research Report
    • Peer Reviewed
  • [Journal Article] A ‘reverse' phylogenetic approach for identification of novel osmoregula-toly and cardiovascular hormones in vertebrates2007

    • Author(s)
      Takei, Y., et. al.
    • Journal Title

      Frontiers Neuroendocrinology 28

      Pages: 143-160

    • Related Report
      2007 Annual Research Report
    • Peer Reviewed
  • [Journal Article] The intestinal guanylin system and seawater adaptation in eels2007

    • Author(s)
      Takei, Y, et. al.
    • Journal Title

      General and Comparative Endocrinology 152

      Pages: 339-351

    • Related Report
      2007 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Osmoregulation in elephant fish, Callorhinchus Milii with special reference to the rectal gland2007

    • Author(s)
      Hyodo, S., et. al.
    • Journal Title

      Journal of Experimental Biology 210

      Pages: 1303-1310

    • Related Report
      2007 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Fish calcitonin receptors have novel features2007

    • Author(s)
      Nag, K, et. al.
    • Journal Title

      General and Comparative Endocrinology 154

      Pages: 48-58

    • Related Report
      2007 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Genomic analyses and cloning of novel chicken natriuretic peptide genes reveal new insights into natriuretic peptide evolution2007

    • Author(s)
      Trajanovska, S., et. al.
    • Journal Title

      Peptides 28

      Pages: 2155-2163

    • Related Report
      2007 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Regulation of ion transport in eel intestine by the homologous guanylin family of peptides2007

    • Author(s)
      Yuge, S., et. al.
    • Journal Title

      Zoological Science 24

      Pages: 1222-1230

    • Related Report
      2007 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Area postrema, a brain circumventricular organ, is the site of antifipso-genic action of circUlating atrial natriuretic peptide in eels2007

    • Author(s)
      Tsukada, T., et. al.
    • Journal Title

      Joumal of Experimental Biology 210

      Pages: 3970-3978

    • Related Report
      2007 Annual Research Report
    • Peer Reviewed
  • [Presentation] 絶水したサバクネズミはたくさん食べてより効率よく代謝水を作る第20回バソプレシン研究会2010

    • Author(s)
      竹井祥郎, 他
    • Organizer
      第20回バソプレシン研究会
    • Place of Presentation
      東京
    • Year and Date
      2010-01-09
    • Related Report
      2009 Annual Research Report
  • [Presentation] How comparative biological studies can impact on other research fields?2009

    • Author(s)
      Takei, Y., et.al.
    • Organizer
      Joint Symposium of three Comparative Biological Societies,
    • Place of Presentation
      Osaka(大阪)
    • Year and Date
      2009-10-23
    • Related Report
      2009 Annual Research Report
  • [Presentation] ウナギはなぜ川と海で生きられるのか?2009

    • Author(s)
      竹井祥郎
    • Organizer
      World Congress of Neurohypophysial Hormones主催市民公開講座「水とからだ」
    • Place of Presentation
      北九州
    • Year and Date
      2009-09-08
    • Related Report
      2009 Annual Research Report
  • [Presentation] 魚類を用いて新規ホルモン・新規機能を同定する:ナトリウム利尿ペプチドおよびアドレノメデュリンファミリー2009

    • Author(s)
      竹井祥郎
    • Organizer
      第6回CEMフォーラム
    • Place of Presentation
      京都
    • Year and Date
      2009-04-04
    • Related Report
      2009 Annual Research Report
  • [Presentation] Multiple guanylins and their receptors in the eel assume their important roles in seawater adaptation2009

    • Author(s)
      Takei, Y, Yuge, S., Ando, M.
    • Organizer
      Sixteenth International Congress of Comparative Endocrinology
    • Place of Presentation
      Hong Kong.
    • Related Report
      2009 Final Research Report
  • [Presentation] Multiple guanylins and their receptors in the eel assume their important roles in seawater adaptation2009

    • Author(s)
      Takei, Y., et al.
    • Organizer
      16^<th> International Congress of Comparative Endocrinology
    • Place of Presentation
      Hong Kong、中国
    • Related Report
      2009 Annual Research Report
  • [Presentation] Evolutionary history of adrenomedullin family in vertebrates revealed by comparative genomic analyses2009

    • Author(s)
      Ogosi, M., et.al.
    • Organizer
      16^<th> International Congress of Comparative Endocrinology
    • Place of Presentation
      Hong Kong、中国
    • Related Report
      2009 Annual Research Report
  • [Presentation] Multiple relaxin-3s in Japanese eel : cDNA cloning, sites of expression and gene expression after seawater acclimation2009

    • Author(s)
      Kusakabe, M., et.al.
    • Organizer
      16^<th> International Congress of Comparative Endocrinology
    • Place of Presentation
      Hong Kong、中国
    • Related Report
      2009 Annual Research Report
  • [Presentation] Qualitative and quantitative changes in plasma angiotensins in eel adapted to different salinities2009

    • Author(s)
      Marty, K.S., et.al.
    • Organizer
      16^<th> International Congress of Comparative Endocrinology
    • Place of Presentation
      Hong Kong、中国
    • Related Report
      2009 Annual Research Report
  • [Presentation] Natriuretic peptide interact with ACTH for cortisol secretion in the eel interrenal2009

    • Author(s)
      Ventura, A., et.al.
    • Organizer
      16^<th> International Congress of Comparative Endocrinology
    • Place of Presentation
      Hong Kong、中国
    • Related Report
      2009 Annual Research Report
  • [Presentation] Potent osmoregulatory actions of homologous natriuretic peptides(ANP, BNP, VNP, CNP1, CNP3 and CNP4)in eel.2009

    • Author(s)
      Miyanishi, H., et.al.
    • Organizer
      16^<th> International Congress of Comparative Endocrinology
    • Place of Presentation
      Hong Kong、中国
    • Related Report
      2009 Annual Research Report
  • [Presentation] Relative cardiovascular actions of six natriuretic peptides(ANP, BNP, VNP, CNP1, CNP3 and CNP4)in eels2009

    • Author(s)
      Nobata, et.al.
    • Organizer
      16^<th> International Congress of Comparative Endocrinology
    • Place of Presentation
      Hong Kong、中国
    • Related Report
      2009 Annual Research Report
  • [Presentation] サンゴと渦鞭毛虫の細胞内共生に関わる遺伝子の解析2009

    • Author(s)
      湯山育子, 他
    • Organizer
      日本動物学会第80回大会
    • Place of Presentation
      静岡
    • Related Report
      2009 Annual Research Report
  • [Presentation] ウナギ腎臓におけるSO_4^<2->輸送の環境イオン濃度による切り替え2009

    • Author(s)
      渡辺太朗, 他
    • Organizer
      日本動物学会第80回大会
    • Place of Presentation
      静岡
    • Related Report
      2009 Annual Research Report
  • [Presentation] ウナギの延髄最後野を介した浸透圧受容と飲水調節2009

    • Author(s)
      野畑重教, 他
    • Organizer
      日本動物学会第80回大会
    • Place of Presentation
      静岡
    • Related Report
      2009 Annual Research Report
  • [Presentation] サバクネズミは絶水によりエネルギー代謝を脂肪から糖に変更する2009

    • Author(s)
      竹井祥郎, 他
    • Organizer
      日本動物学会第80回大会
    • Place of Presentation
      静岡
    • Related Report
      2009 Annual Research Report
  • [Presentation] A reverse phylogenetic approach for identification of novel cardiovascular and osmoregulatory hormones2009

    • Author(s)
      Takei, Y., et.al.
    • Organizer
      Satellite Symposium of the 9^<th> International Symposium on VIP, PACAP and Related Peptides, Phylogenetic Aspects of Neuropeptides
    • Place of Presentation
      Yakushima(屋久島)
    • Related Report
      2009 Annual Research Report
  • [Presentation] メダカの初期発生におけるナトリウム利尿ペプチドの発現。2009

    • Author(s)
      宮西弘, 他
    • Organizer
      第34回比較内分泌学会大会・日本比較生理生化学会31回大会合同大会
    • Place of Presentation
      大阪
    • Related Report
      2009 Annual Research Report
  • [Presentation] ウナギにおけるウロテンシンII関連ペプチドの道程と循環・飲水調節作用2009

    • Author(s)
      野畑重教, 他
    • Organizer
      第34回比較内分泌学会大会・日本比較生理生化学会31回大会合同大会
    • Place of Presentation
      大阪
    • Related Report
      2009 Annual Research Report
  • [Presentation] Which K channels are important for osmoregulation in the marine teleost intestine?2009

    • Author(s)
      Healy, J., et.al.
    • Organizer
      第34回比較内分泌学会大会・日本比較生理生化学会31回大会合同大会
    • Place of Presentation
      大阪
    • Related Report
      2009 Annual Research Report
  • [Presentation] Exploring essential seawater-adapting hormones in fish2008

    • Author(s)
      Takei, Y, Tsukada, T., Yuge, S., Ogoshi, M., Inoue, K.
    • Organizer
      Sixth International Symposium on Fish Endocrinology
    • Place of Presentation
      Calgary, Canada
    • Related Report
      2009 Final Research Report
  • [Presentation] Integrative approach to adaptation in hyperosmotic marineenVironment2007

    • Author(s)
      Takei, Y., et. al.
    • Organizer
      6^〈th〉Okazaki Biology Conference:Marine Biology
    • Place of Presentation
      Okazaki Japan
    • Year and Date
      2007-12-03
    • Related Report
      2007 Annual Research Report
  • [Presentation] 系統発生学的アプローチによる新しい心・血管ホルモンの探索:ナトリウム利尿ペプチドとアドレノメデュリン2007

    • Author(s)
      竹井 祥郎, 他
    • Organizer
      第11回日本心血管内分泌代謝術総会シンポジウム
    • Place of Presentation
      東京
    • Year and Date
      2007-11-16
    • Related Report
      2007 Annual Research Report
  • [Presentation] アドレノメデュリン5のラット中枢内投与による下垂体後葉ホルモン分泌と昇圧作用についての検討2007

    • Author(s)
      大坪 広樹, 他
    • Organizer
      第11回日本心血管内分泌代謝学術総会シンポジウム
    • Place of Presentation
      東京
    • Year and Date
      2007-11-16
    • Related Report
      2007 Annual Research Report
  • [Presentation] 体液調節の統合生理学:未解決の問題点2007

    • Author(s)
      竹井 祥郎, 他
    • Organizer
      東京大学海洋研究所研究集会「魚類の適応と進化の統合生物学:遺伝子から行動まで」
    • Place of Presentation
      東京
    • Year and Date
      2007-11-15
    • Related Report
      2007 Annual Research Report
  • [Presentation] Evolutionary history of the CGRP family in vertebrates2007

    • Author(s)
      Takei, Y., et. al.
    • Organizer
      6^〈th〉International Symposium on the CGRP family
    • Place of Presentation
      San Diego,USA
    • Year and Date
      2007-10-31
    • Related Report
      2007 Annual Research Report
  • [Presentation] Cardiovascular actions of adrenomedullins in eels (Anguilla japonica)2007

    • Author(s)
      Nobata, S., et. al.
    • Organizer
      6^〈th〉International Symposium on the CGRP family
    • Place of Presentation
      San Diego,USA
    • Year and Date
      2007-10-31
    • Related Report
      2007 Annual Research Report
  • [Presentation] 海に生きる多様な機能戦略を探る2007

    • Author(s)
      竹井 祥郎, 他
    • Organizer
      第40回海中底工学フォーラム
    • Place of Presentation
      東京
    • Year and Date
      2007-10-26
    • Related Report
      2007 Annual Research Report
  • [Presentation] ウナギの血中心房性ナトリウム利尿ペプチドの飲水抑制効果における脳内作用部位の同定2007

    • Author(s)
      野畑 重教, 他
    • Organizer
      第78回日本動物学会大会
    • Place of Presentation
      弘前
    • Year and Date
      2007-09-20
    • Related Report
      2007 Annual Research Report
  • [Presentation] ウナギにおける新規アドレノメデュリンファミリーの循環・体液調節作用2007

    • Author(s)
      御輿 真穂, 他
    • Organizer
      第78回日本動物学会大会
    • Place of Presentation
      弘前
    • Year and Date
      2007-09-20
    • Related Report
      2007 Annual Research Report
  • [Presentation] Effects of central adlministration of adrenomedullin 2(AM2) on oxytocin-secreting neurons and localization of AM2-like immunoreactive cells in rat brain2007

    • Author(s)
      Hashimoto, H., et. al.
    • Organizer
      7^〈th〉World Congress of Neuroypophysial Hormones
    • Place of Presentation
      Regrenburg,Germany
    • Year and Date
      2007-09-18
    • Related Report
      2007 Annual Research Report
  • [Presentation] Effbcts of centrany administerred adrenomedullin5 on the hypohtalamo -neurohypophysial system in conscious rats2007

    • Author(s)
      OtSubo, H., et. al.
    • Organizer
      7^〈th〉World Congress of Neuroypophysial Hormones
    • Place of Presentation
      Regrenburg,Germany
    • Year and Date
      2007-09-18
    • Related Report
      2007 Annual Research Report
  • [Presentation] 魚類の回遊と浸透圧調節:未解決の問題点2007

    • Author(s)
      竹井 祥郎, 他
    • Organizer
      東京大学海洋研究所シンポジウム「三陸と海:その魅力と生物学」
    • Place of Presentation
      釜石
    • Year and Date
      2007-08-21
    • Related Report
      2007 Annual Research Report
  • [Presentation] ラット脳内におけるアドレノメデュリン2の局在と中枢性オキシトシン分泌作用における特異的受容体の検討2007

    • Author(s)
      橋本 弘史, 他
    • Organizer
      第34回日本神経内分泌学会学術集会
    • Place of Presentation
      前橋
    • Year and Date
      2007-08-04
    • Related Report
      2007 Annual Research Report
  • [Presentation] アドレノメデュリン5のラットの脳室内投与によるFos蛋白の脳内発現分布2007

    • Author(s)
      大坪 広樹, 他
    • Organizer
      第80回目本内分泌学会学術総会
    • Place of Presentation
      東京
    • Year and Date
      2007-06-14
    • Related Report
      2007 Annual Research Report
  • [Presentation] Evolutionary history of the CGRP family in vertebrates2007

    • Author(s)
      Takei, Y., Ogoshi, M.
    • Organizer
      Sixth International Symposium on the CGRP family
    • Place of Presentation
      San Diego, USA.
    • Related Report
      2009 Final Research Report
  • [Book] The gastrointestinal tract as an endocrine, paracrine and autocrine organ. In : Fish Physiology Vol. 30 : The Multifunctional Gut of Fish (M. Grosell, A. P. Farrell, and C. J. Brauner)2010

    • Author(s)
      Takei, Y., Loretz, C. A.
    • Publisher
      Academic Press(in press)
    • Related Report
      2009 Final Research Report
  • [Book] 生理活性物質 生物学大辞典(石川統編)2010

    • Author(s)
      竹井祥郎
    • Publisher
      東京化学同人(印刷中)
    • Related Report
      2009 Annual Research Report
  • [Book] The gastrointestinal tract as an endocrine, paracrine and autocrine organ. In : Fish Physiology Vol.30 : The Multifunctional Gut of Fish (M.Grosell, A.P.Farrell, and C.J.Brauner) Fish Physiology, Vol.28 : Fish Neuroendocrinology (Eds.N.Bernier, G.Van Der Kraak, A.P.Farrell and C.J.Brauner).2010

    • Author(s)
      Takei, Y., Loretz, C.A.
    • Publisher
      Academic Press(印刷中)
    • Related Report
      2009 Annual Research Report
  • [Book] Molecular and functional evolution of the adrenomedullin family in vertebrates : What do fish studies tell us? In : The Calcitonin Gene-Related Peptide Family : Form, Function and Future Perspectives. (Eds. D. L. Hay and I. Dickerson)2009

    • Author(s)
      Takei, Y., Ogoshi, M., Wong, M. K., Nobata, S.
    • Publisher
      Springer Verlag
    • Related Report
      2009 Final Research Report
  • [Book] The neuroendocrine regulation of fluid intake and fluid balance. In : Fish Physiology, Vol. 28 : Fish Neuroendo- crinology (Eds. N. Bernier, G. Van Der Kraak, A. P. Farrell and C. J. Brauner)2009

    • Author(s)
      Takei, Y., Balment, R. J.
    • Publisher
      Academic Press, Academic Press
    • Related Report
      2009 Final Research Report
  • [Book] 魚類の水代謝「からだと水の事典」2008

    • Author(s)
      竹井祥郎
    • Publisher
      朝倉書店
    • Related Report
      2008 Annual Research Report
  • [Book] 恒常性とホルモン「内分泌と生命活動」シリーズ21世紀の動物科学10巻2007

    • Author(s)
      竹井 祥郎
    • Total Pages
      209
    • Publisher
      培風館
    • Related Report
      2007 Annual Research Report
  • [Book] 動物個体の維持理系総合のための生命科学21章2007

    • Author(s)
      竹井 祥郎
    • Total Pages
      268
    • Publisher
      羊土社
    • Related Report
      2007 Annual Research Report
  • [Book] レニン・アンジオテンシン系「ホルモンハンドブック新訂eBook版」2007

    • Author(s)
      竹井 祥郎
    • Total Pages
      1267
    • Publisher
      南江堂
    • Related Report
      2007 Annual Research Report
  • [Book] ナトリウム利尿ペプチドファミリー「ホルモンハンドブック新訂eBook版」2007

    • Author(s)
      竹井 祥郎
    • Total Pages
      1267
    • Publisher
      南江堂
    • Related Report
      2007 Annual Research Report
  • [Remarks] ホームページ等

    • URL

      http://physiol.ori.u-tokyo.ac.jp/seiri/

    • Related Report
      2009 Final Research Report
  • [Remarks]

    • URL

      http://physiol.ori.u-tokyo.ac.jp/seiri/

    • Related Report
      2009 Annual Research Report

URL: 

Published: 2007-04-01   Modified: 2017-10-12  

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