Non-verbal executive function in the left frontal lobe in patients with brain tumor resection
| Project/Area Number |
19300093
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| Research Category |
Grant-in-Aid for Scientific Research (B)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Cognitive science
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| Research Institution | National Institute of Advanced Industrial Science and Technology |
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Principal Investigator |
KUMADA Takatsune National Institute of Advanced Industrial Science and Technology, 人間福祉医工学研究部門, 研究グループ長 (70221942)
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| Co-Investigator(Kenkyū-buntansha) |
MYRAGAKI Yoshihiro 東京女子医科大学, 脳神経外科, 准教授 (70210028)
MARUYAMA Takashi 東京女子医科大学, 脳神経外科, 講師 (40301543)
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| Project Period (FY) |
2007 – 2009
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| Project Status |
Completed (Fiscal Year 2009)
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| Budget Amount *help |
¥12,350,000 (Direct Cost: ¥9,500,000、Indirect Cost: ¥2,850,000)
Fiscal Year 2009: ¥3,250,000 (Direct Cost: ¥2,500,000、Indirect Cost: ¥750,000)
Fiscal Year 2008: ¥3,640,000 (Direct Cost: ¥2,800,000、Indirect Cost: ¥840,000)
Fiscal Year 2007: ¥5,460,000 (Direct Cost: ¥4,200,000、Indirect Cost: ¥1,260,000)
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| Keywords | 前頭葉 / 注意 / 遂行機能 / 脳波 / 脳機能イメージング |
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| Research Abstract |
We examined task-switching functions of frontal regions in patients with brain tumor using intracranial electrodes and voxel-based lesion symptom mapping (VLSM) techniques. In Study 1, EEG was recorded via electrodes planted in the left frontal lobe of a patient. An electrode in the left inferior frontal sulcus recorded negative potentials to the onset of a cue.In Study 2, 29 patients performed a cued visual search task. Their performance and resected brain areas were subjected to a VLSM procedure, showed that the left middle frontal region involved in configuration of task-set, whereas the left inferior frontal regions involved in maintenance of it. These results revealed that left frontal regions have different functions related to task-switching.
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Report
(4 results)
Research Products
(10 results)
