Mechanism of increase inphysical activity using a novel animal model of high wheel running
| Project/Area Number |
19300222
|
|---|
| Research Category |
Grant-in-Aid for Scientific Research (B)
|
| Allocation Type | Single-year Grants |
|---|
| Section | 一般 |
|---|
| Research Field |
Sports science
|
|---|
| Research Institution | The University of Tokushima |
|---|
Principal Investigator |
NAKAYA Yutaka The University of Tokushima, 大学院・ヘルスバイオサイエンス研究部, 教授 (50136222)
|
|---|
| Co-Investigator(Renkei-kenkyūsha) |
HARADA NAGAKATSU 徳島大学, 大学院・ヘルスバイオサイエンス研究部, 助教 (40359914)
|
|---|
| Project Period (FY) |
2007 – 2009
|
| Project Status |
Completed (Fiscal Year 2009)
|
| Budget Amount *help |
¥19,890,000 (Direct Cost: ¥15,300,000、Indirect Cost: ¥4,590,000)
Fiscal Year 2009: ¥3,640,000 (Direct Cost: ¥2,800,000、Indirect Cost: ¥840,000)
Fiscal Year 2008: ¥4,290,000 (Direct Cost: ¥3,300,000、Indirect Cost: ¥990,000)
Fiscal Year 2007: ¥11,960,000 (Direct Cost: ¥9,200,000、Indirect Cost: ¥2,760,000)
|
|---|
| Keywords | スポーツ栄養学 / 運動 / インスリン抵抗性 / 海馬 / 心肥大 / 交感神経 / 脂肪細胞 / カルシウムチャネル / β遮断薬 / SPORTSラット / エピネフリン / 肥満 / 脂肪 / グレリン / ユビキチン / モノアミン / インスリン感受性 / 心拍数 / 培養心筋細胞 |
|---|
| Research Abstract |
To understand mechanisms of modified physical activities, we studied neuropsychological characteristics in SPORTS rat. In the hippocampus of SPORTS rats, the levels of norepinephrine (NE) in the extracellular fluid were increased, whereas those in the whole homogenate of the tissue were decreased. The protein expression and the activity levels of monoamine oxidase A (MAOA) were decreased in the hippocampus of SPORTS rats, suggesting that the elevation of extracellular NE by decreased MAOA activities in hippocampus determine the neural basis of the psychological regulation of exercise motives in the SPORTS rats.
|
Report
(4 results)
Research Products
(36 results)
-
[Journal Article] beta-Adrenergic-AMPK pathway phosphorylates acetyl-CoA carboxylase in a high-epinephrine rat model2010
Author(s)
Hattori A, Mawatari K, Tsuzuki S, Yoshioka E, Toda S, Yoshida M, Yasui 5, Furukawa H, Morishima M, Ono K, Ohnishi T, Nakano M, Harada N, Takahashi A, Nakaya Y
-
Journal Title
SPORTS. Obesity 18
Pages: 48-54
Related Report
Peer Reviewed
-
-
-
-
[Journal Article] Dietary phosphorus acutely impairs endothelial function.2009
Author(s)
Shuto E, Taketani Y, Tanaka R, Harada N, Isshiki M, Sato M, Nashiki K, Amo K, Yamamoto H, Higashi Y, Nakaya Y, Takeda E
-
Journal Title
J Am Soc Nephrol 20
Pages: 1504-1512
Related Report
Peer Reviewed
-
-
-
-
-
-
-
[Journal Article] Alternative splicing produces a constitutively active form of human SREBP-1.2008
Author(s)
Harada N, Yonemoto H, Yoshida M, Yamamoto H, Yin Y, Miyamoto A, Hattori A, Wu Q, Nakagawa T, Nakano M Teshigawara K, Mawatari K, Hosaka T, Takahashi A, Nakaya Y
-
Journal Title
Related Report
Peer Reviewed
-
[Journal Article] Reactive oxygen species induced by diamide inhibit insulin-induced ATP-sensitive potassium channel activation in cultured vascular smooth muscle cells.2008
Author(s)
Mawatari K, Yasui S, Morizumi R, Hamamoto A, Furukawa H, Koyama K, Hattori A, Yoshioka E, Yoshida M, Nakano M, Teshigawara K, Harada N, Hosaka T, Takahashi A, Nakaya Y
-
Journal Title
Asia Pac J Clin Nutr 17Suppl1
Pages: 162-166
Related Report
Peer Reviewed
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
