| Budget Amount *help |
¥15,730,000 (Direct Cost: ¥12,100,000、Indirect Cost: ¥3,630,000)
Fiscal Year 2009: ¥4,550,000 (Direct Cost: ¥3,500,000、Indirect Cost: ¥1,050,000)
Fiscal Year 2008: ¥4,160,000 (Direct Cost: ¥3,200,000、Indirect Cost: ¥960,000)
Fiscal Year 2007: ¥7,020,000 (Direct Cost: ¥5,400,000、Indirect Cost: ¥1,620,000)
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| Research Abstract |
The author examined the effect of microwave irradiation on Escherichia coli O157. When the cell was heated with microwave oven, the survival and acid resistance were decreased. The verocytotoxin (VT) produced by the cells cultured for 24h after the microwave-treatment was less than that produced by untreated cells. Microwave also reduced the pathogenicity of the cells in foods. Microwave irradiation to the pathogen at 37℃ with a microwave irradiator also reduced the pathogenicity. The transcription of VT gene was delayed by microwave irradiation. The VT gene expression was regulated by the quorum sensing system, and microwave irradiation was found to activate SdiA in the system. Microwave is useful for preventing food poisoning by E.coli O157.
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