Life time control of biodegradable composites for scaffolds in bone tissue engineering
Project/Area Number |
19360050
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Research Category |
Grant-in-Aid for Scientific Research (B)
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Allocation Type | Single-year Grants |
Section | 一般 |
Research Field |
Materials/Mechanics of materials
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Research Institution | Kyoto University |
Principal Investigator |
HOJO Masaki Kyoto University, 工学研究科, 教授 (70252492)
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Co-Investigator(Kenkyū-buntansha) |
ADACHI Taiji 京都大学, 工学研究科, 准教授 (40243323)
田中 基嗣 金沢工業大学, 基礎教育部, 講師 (30346085)
西野 孝 神戸大学, 工学部, 教授 (40180624)
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Co-Investigator(Renkei-kenkyūsha) |
TANAKA Mototsugu 金沢工業大学, 工学部, 講師 (30346085)
NISHINO Takashi 神戸大学, 工学部, 教授 (40180624)
|
Project Period (FY) |
2007 – 2009
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Project Status |
Completed (Fiscal Year 2009)
|
Budget Amount *help |
¥19,500,000 (Direct Cost: ¥15,000,000、Indirect Cost: ¥4,500,000)
Fiscal Year 2009: ¥4,940,000 (Direct Cost: ¥3,800,000、Indirect Cost: ¥1,140,000)
Fiscal Year 2008: ¥6,110,000 (Direct Cost: ¥4,700,000、Indirect Cost: ¥1,410,000)
Fiscal Year 2007: ¥8,450,000 (Direct Cost: ¥6,500,000、Indirect Cost: ¥1,950,000)
|
Keywords | 材料設計 / プロセス / 物性 / 評価 / 複合材料 / 生分解性樹脂 / 組織再生工学 / ハイドロキシアパタイト / ポリ乳酸 / スカフォールド / 骨リモデリング / 機械材料・材料力学 / 複合材料・物性 / 構造・機能材料 / HAp / Hap |
Research Abstract |
Hydroxyapatite (HAp)/poly-L-lactic acid (PLLA) composite material was developed for the development of biodegradable three-dimensional porous scaffolds for bone tissue engineering. Both particle and fiber type HAp was compared Interface control was also tried for HAp particle. These mesoscopic factors had great influence on the deformation and fracture behavior of HAp/PLLA composites. Moreover, hydrolysis of this composite material was strongly affected by the surface treatment of HAp particles.
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Report
(4 results)
Research Products
(45 results)
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[Journal Article] Mode I fatigue delamination of Zanchor-reinforced CF/epoxy laminates.2010
Author(s)
Hojo, M., Nakashima, K., Kusaka, T., Tanaka, M., Adachi, T., Fukuoka T., Ishibashi, M.
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Journal Title
International Journal of Fatigue Vol.32
Pages: 37-45
Related Report
Peer Reviewed
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[Journal Article] Effect of fiber array irregularities on microscopic interfacial normal stress states of transversely loaded UD-CFRP from viewpoint of failure initiation2009
Author(s)
Hojo, M., Mizuno, M., Hobbiebrunken, T., Adachi, T., Tanaka, M., Ha, S.K.
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Journal Title
Composites Science and Technology 69(11-12)
Pages: 1726-1734
NAID
Related Report
Peer Reviewed
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[Journal Article] Computer simulation of trabecular remodeling in human proximal femur using large-scale voxel FE models: Approach to understanding Wolff's law2009
Author(s)
Tsubota, K., Suzuki, Y., Yamada, T., Hojo, M., Makinouchi, A., Adachi, T.
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Journal Title
Journal of Biomechanics Vol.42,Issue8
Pages: 1088-1094
Related Report
Peer Reviewed
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[Journal Article] Two different mechanisms of fatigue damage due to cyclic stress loading at 77 K for MOCVD-YBCO-coated conductors2008
Author(s)
Sugano, M., Yoshida, Y., Hojo, M., Shikimachi, K., Hirano, N., Nagaya, S.
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Journal Title
Superconductor Science and Technology 21
Pages: 54006-54006
Related Report
Peer Reviewed
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[Journal Article] Effects of spatial distribution of defects on bending deformation and critical current in Bi2223/Ag superconducting composite tapes2007
Author(s)
Hojo, M., Nakamura, M., Tanaka, M., Adachi, T., Sugano, M., Ochiai, S. and Osamura, K.
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Journal Title
Materials Science Forum 539-543
Pages: 739-744
Related Report
Peer Reviewed
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[Journal Article] Direct measurement of mechanical properties of Bi2223 filament using Ag alloy removed tape2007
Author(s)
Hojo, M., Hashimoto, M., Tanaka, M., Adachi, T., Sugano, M., Ochiai, S. and Osamura, K.
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Journal Title
Physica C 463-465
Pages: 863-866
Related Report
Peer Reviewed
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[Presentation] Change in Deformation/Fracture Behavior of Interface- Controlled HAp/PLLA Composites by ydrolysis2009
Author(s)
Tanaka, M., Tanaka, H., Hojo, M., Adachi, T., Sugihara, M., Kotera, M., Nishino, T.
Organizer
Proceedings of 17th International Conference on Composite Materials
Place of Presentation
Edinburg
Related Report
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[Presentation] Damage Initiation under Transverse Loading of UD-CFRP with Random Fiber Arrangement2009
Author(s)
Hojo, M., Mizuno, M., Hobbiebrunken, T., Adachi, T., , Jin, K.K.
Organizer
Fourth China-Europe Symposium on Processing and Properties of Reinforced Polymers p. 17
Place of Presentation
Guilin, China
Related Report
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[Patent(Industrial Property Rights)] 三次元製織装置および三次元製織方法2007
Inventor(s)
北條, 安達, 日和, 馬場, 井上, 井元, 田中
Industrial Property Rights Holder
JST, 京大学, 神大, NIRO, アルブラスト, 井元製作所
Filing Date
2007-08-07
Related Report
Overseas