Study on sperm motility and fertility

• Project/Area Number: 19370028
• Research Category: Grant-in-Aid for Scientific Research (B)
• Allocation Type: Single-year Grants
• Section: 一般
• Research Field: Animal physiology/Animal behavior
• Research Institution: The University of Tokyo
• Principal Investigator: YOSHIDA Manabu The University of Tokyo, 大学院・理学系研究科附属臨海実験所, 講師 (60301785)
• Co-Investigator(Kenkyū-buntansha): YOSHIDA Kaoru 桐蔭横浜大学, 先端医用工学センター, 助教 (70398973)
• Project Period (FY): 2007 – 2008
• Project Status: Completed (Fiscal Year 2008)
• Budget Amount: ¥18,070,000 (Direct Cost: ¥13,900,000、Indirect Cost: ¥4,170,000); Fiscal Year 2008: ¥7,670,000 (Direct Cost: ¥5,900,000、Indirect Cost: ¥1,770,000); Fiscal Year 2007: ¥10,400,000 (Direct Cost: ¥8,000,000、Indirect Cost: ¥2,400,000)
• Keywords: 受精 / 精子活性化 / 誘引物質 / 精子受精能阻害物質 / 精子走化性 / 受精能獲得 / カタユウレイボヤ / マウス / 精子活性化・誘引物質 / 動物生理化学 / カタユウレボヤ

Research Abstract

受精の過程において精子の運動能・受精能が調節されるメカニズムについて解明することを目的とし、本課題においては、主に精子走化性運動調節機構、及び精漿による精子の受精能調節機構の2点に研究内容を絞って研究を推進した。そして、精子走化性においては精子誘引物質による精子鞭毛内Ca^(2+)濃度上昇が鞭毛運動の変化となり、走化性運動に顕著な方向転換となっていること、マウス精子の受精能獲得は精漿タンパク質SVS2が精子表面のガングリオシドGM1と結合することで抑制されること、ヒト精子の受精能抑制は精漿タンパク質SgとZn^(2+)により制御されていることなどが明らかとなった。

Research Products

• [Journal Article] Functional implications of membrane modification with semenogelins for inhibition of sperm motility in humans (2009)
  • Author(s): Yoshida, K., Krasznai, Z.T., Krasznai, Z., Yoshiike, M., Kawano, N., Yoshida, M., Morisawa, M., Toth, Z., Bazsane, Z.K., Marian, T., & Iwamoto, T.
  • Journal Title: Cell Motil. Cytoskeleton 66 Pages: 99-108
  • Peer Reviewed
• [Journal Article] Phosphorylation of the MAPK pathway has an essential role in the acrosome reaction in miniature pig sperm (2009)
  • Author(s): Kawano, N., Ito, J., Kashiwazaki, N., & Yoshida, M.
  • Journal Title: Reprod. Dom. Animal
  • Peer Reviewed
• [Journal Article] Functional implications of membrane modification with semenogelins for inhibition of sperm motility in humans (2009)
  • Author(s): Yoshida, K. 他10名
  • Journal Title: Cell Motility and the Cytoskeleton 66 Pages: 99-108
  • Peer Reviewed
• [Journal Article] Physiological roles of semenogelin and zinc in sperm motility and semen coagulation at ejaculation in human (2008)
  • Author(s): Yoshida, K., Kawano, N., Yoshiike, M., Yoshida, M., Iwamoto, T., & Morisawa, M.
  • Journal Title: Mol. Hum. Reprod 14 Pages: 151-156
  • Peer Reviewed
• [Journal Article] Prostaglandins in rainbow trout (Oncorhynchus mykiss WALBAUM, 1792) sperm biology - searching for answers (2008)
  • Author(s): Kowalski, R.K., Shiba, K., Yoshida, M., & Glogowski, J.
  • Journal Title: J. Appl. Ichthyol 24 Pages: 487-491
  • Peer Reviewed
• [Journal Article] Control of Sperm Motility and Fertility : Diverse factors and common mechanisms (2008)
  • Author(s): Yoshida, M., Kawano, N., & Yoshida, K.
  • Journal Title: Cell. Mol. Life Sci 65 Pages: 3446-3457
  • Peer Reviewed
• [Journal Article] Valosin-containing protein/p97 interacts with sperm-activating and sperm-attracting factor (SAAF) in the ascidian egg and modulates sperm-attracting activity. (2008)
  • Author(s): Kondoh, E., Konno, A., Inaba, K., Oishi, T., Murata, M., & Yoshida, M.
  • Journal Title: Dev. Growth Differ 50 Pages: 665-673
  • NAID: 10022020622
  • Peer Reviewed
• [Journal Article] Ascidian sperm activating and attracting factor : Importance of sulfate groups for the activities and implication of its putative receptor (2008)
  • Author(s): Yoshida, M., Yoshida, K., Shiba, K., Tsuchikawa, H., Ootou, O., Oishi, T., & Murata, M.
  • Journal Title: FEBS lett 582 Pages: 3429-3433
  • Peer Reviewed
• [Journal Article] Ganglioside GM1 mediates decapacitation effects of SVS2 on murine spermatozoa (2008)
  • Author(s): Kawano, N., Yoshida, K., Iwamoto, T., & Yoshida, M.
  • Journal Title: Biol. Reprod 79 Pages: 1153-1159
  • Peer Reviewed
• [Journal Article] Ca^<2+> bursts occur around a local minimal concentration of attractant and trigger sperm chemotactic response (2008)
  • Author(s): Shiba, K., Baba, S., Inoue, T., Yoshida, M.
  • Journal Title: Proc. Natl. Acad. Sci. USA 105 Pages: 19311-19316
  • Peer Reviewed
• [Journal Article] Two egg-derived molecules in sperm motility initiation and fertilization in the Pacific herring (Clupea pallasi) (2008)
  • Author(s): Cherr, G.N., Morisawa, M., Vines, C.A., Yoshida, K., Smith, E.H., Matsubara, T., Pillai, M.C., Griffin, F.J., & Yanagimachi, R.
  • Journal Title: Int. J. Dev. Biol 52 Pages: 743-752
  • Peer Reviewed
• [Journal Article] Control of Sperm Motility and Fertility: Diverse factors and common mechanisms (2008)
  • Author(s): Yoshida, M. 他2名
  • Journal Title: Cellular and Molecular Life Sciences 65 Pages: 3446-3457
  • Peer Reviewed
• [Journal Article] Valosin-containing protein/p97 interacts with sperm-activating and sperm-attracting factor (SAAF) in the ascidian egg and modulates sperm-attracting activity. (2008)
  • Author(s): Kondoh, E. 他5名
  • Journal Title: Development Growth & Differentiation 50 Pages: 665-673
  • Peer Reviewed
• [Journal Article] Ascidian sperm activating and attracting factor: Importance of sulfate groups for the activities and implication of its putative receptor. (2008)
  • Author(s): Yoshida, M. 他6名
  • Journal Title: FEBS letters 582 Pages: 3429-3433
  • Peer Reviewed
• [Journal Article] Ganglioside GM1 mediates decapacitation effects of SVS2 on murine spermatozoa (2008)
  • Author(s): Kawano, N. 他3名
  • Journal Title: Biology of Reproduction 79 Pages: 1153-1159
  • Peer Reviewed
• [Journal Article] Ca2+ bursts occur around a local minimal concentration of attractant and trigger sperm chemotactic response. (2008)
  • Author(s): Shiba, K. 他3名
  • Journal Title: Proceedings of the National Academy Sciences USA 105 Pages: 19311-19316
  • Peer Reviewed
• [Journal Article] Two egg-derived molecules in sperm motility initiation and fertilization in the Pacific herring (Clupea pallasi). (2008)
  • Author(s): Cherr, G.N. 他8名
  • Journal Title: International Journal of. Developmental Bioogy 52 Pages: 743-752
  • Peer Reviewed
• [Journal Article] How to Track Spermatozoa using High-Speed Visual Feedback. (2008)
  • Author(s): Oku, H. 他4名
  • Journal Title: Conference Proceedings of the IEEE Engineering in Medicine and Biology Society 2008 Pages: 125-128
  • Peer Reviewed
• [Journal Article] Physiological roles of semenogelin and zinc in sperm motility and semen coagulation at ejaculation in human (2008)
  • Author(s): Yoshida, Kaoru, 他5名
  • Journal Title: Molecular Human Reproduction 14 Pages: 151-156
  • Peer Reviewed
• [Journal Article] Seminal vesicle protein, secretion 2 (SVS2) controls mouse sperm fertility (2007)
  • Author(s): Kawano, N., & Yoshida, M.
  • Journal Title: Biol. Reprod 76 Pages: 353-361
  • Peer Reviewed
• [Journal Article] Requirement of methotrex-ate in combination with anti-tumor necrosis factor-alpha therapy for adequate suppression of osteoclastogenesis in rheumatoid arthritis (2007)
  • Author(s): Matsuno, H., Yoshida, K., Ochiai, A., & Okamoto, M.
  • Journal Title: J. Rheumatol 34 Pages: 2326-2333
  • Peer Reviewed
• [Journal Article] Comparative analysis of interindividual variations in the seminal plasma proteome of fertile men with identification of potential markers for azoospermia in infertile patients (2007)
  • Author(s): Yamakawa, K., Yoshida,. K, Nishikawa, H. Kato, T., & wamoto, T.
  • Journal Title: J. Androl 28 Pages: 858-865
  • Peer Reviewed
• [Presentation] カタユウレイボヤ精子走化性における誘引物質感知機構 (2009)
  • Author(s): 柴小菊, 宮代大輔, 上村慎治, 馬場昭次, 吉田学
  • Organizer: 生体運動合同班会議
  • Place of Presentation: 東京
• [Presentation] カタユウレイボヤ精子走化性における誘引物質感知機構 (2009)
  • Author(s): 柴小菊 他4名
  • Organizer: 生体運動合同班会議
  • Place of Presentation: 東京都目黒区
• [Presentation] Prostaglandins level of the seminal plasma and testes of XY, YY, and XX rainbow trout (Oncorhynchus mykiss)/ニジマスXY, YY, XX 雄の精漿及び精巣のプロスタグランジンの比較 (2008)
  • Author(s): R. K. Kowalski, 吉田学, J. Glogowski.
  • Organizer: 日本動物学会関東支部第60回大会
  • Place of Presentation: 駒場
  • Year and Date: 2008-03-22
• [Presentation] 高速ビジュアルフィードバックを用いたトラッキング顕微鏡によるホヤ精子運動の長時間長距離観察 (2008)
  • Author(s): 柴小菊, 奥寛雅, 尾川順子, 石川正俊, 吉田学
  • Organizer: 日本動物学会関東支部第60回大会
  • Place of Presentation: 駒場
  • Year and Date: 2008-03-22
• [Presentation] カルシウムによるカタユウレイボヤ精子走化性時の鞭毛運動制御 (2008)
  • Author(s): 柴小菊, 丸山虎徹, 馬場昭次, 吉田 学
  • Organizer: 生体運動合同班会議
  • Place of Presentation: 仙台
• [Presentation] Characterization of VCP/p97 and its roles in the activation of sperm motility in Ciona intestinalis (2008)
  • Author(s): 朱麗紅, 近藤江里, 吉田 学, 稲葉一男
  • Organizer: 生体運動合同班会議
  • Place of Presentation: 仙台
• [Presentation] Valosin containing protein VCP/p97 binds to the sperm attractant SAAF and may control its release from the ascidian egg (2008)
  • Author(s): Kondoh, E., Konno, A., Inaba, K., Oishi, T., Murata, M., and Yoshida, M.
  • Organizer: 41st Society for the Study of Reproduction Annual Meeting
  • Place of Presentation: Kailua-Kona, HI, USA
• [Presentation] Ca^<2+> Dynamics and Chemotactic Behavior of the Ascidian Sperm (2008)
  • Author(s): Yoshida, M., Shiba K., and Baba, S.A.
  • Organizer: 41st Society for the Study of Reproduction Annual Meeting
  • Place of Presentation: Kailua-Kona, HI, USA
• [Presentation] 精嚢分泌タンパク質semenogelinの精子膜電位および膜透過性への影響 (2008)
  • Author(s): 吉田薫,吉池美紀,吉田学,森沢正昭、Zoltan Krasznai、Terez Marian、岩本晃明
  • Organizer: 日本アンドロロジー学会第27回学術集会
  • Place of Presentation: 京都
• [Presentation] How to Track Spermatozoa using High-Speed Visual Feedback (2008)
  • Author(s): Oku, H., Ogawa, J., Shiba, K., Yoshida, M. and Ishikawa, M
  • Organizer: 30th Annual International Conference of the IEEE Engineering in Medicine and Biology Society
  • Place of Presentation: Vancouver, British Columbia, Canada
• [Presentation] カタユウレイボヤ精子の誘引物質濃度変化感知機構 (2008)
  • Author(s): 柴小菊, 馬場昭次, 吉田学
  • Organizer: 日本動物学会第79回大会
  • Place of Presentation: 福岡
• [Presentation] カタユウレイボヤ精子走化性運動における精子内Ca^<2+> 濃度の制御機構 (2008)
  • Author(s): 丸山虎徹, 柴小菊, 吉田学
  • Organizer: 日本動物学会第79回大会
  • Place of Presentation: 福岡
• [Presentation] メダカの生殖におけるCOX阻害剤の効果 (2008)
  • Author(s): R. K. Kowalski, 吉田学
  • Organizer: 日本動物学会第79回大会
  • Place of Presentation: 福岡
• [Presentation] イトマキヒトデAsterina pectinifera精子の運動開始機構 (2008)
  • Author(s): 荒木直也, 吉田学, 森澤正昭
  • Organizer: 日本動物学会第79回大会
  • Place of Presentation: 福岡
• [Presentation] Sperm subpopulation in rainbow trout (Oncorhynchus mykiss)-CASA results and derived phenomenological criteria (2008)
  • Author(s): Kowalski, R.K., Peixinho, J., Shiba, K., Yoshida, K., Sarosiek, B., and Yoshida, M.
  • Organizer: Aquaculture Europe 08
  • Place of Presentation: Krakow, Poland
• [Presentation] Bovine serum albumin prevents calcium influx induced by ionomycin and progesterone in rainbow trout sperm cells (2008)
  • Author(s): Kowalski, R.K., Glogowski, J., Yoshida, K., Shiba, K., and Yoshida, M.
  • Organizer: Aquaculture Europe 08
  • Place of Presentation: Krakow, Poland
• [Presentation] Effect of albumin, casein and hemoglobin on short-term preservation of rainbow trout sperm (2008)
  • Author(s): Kowalski, R.K., Yoshida, M., Yoshida, K., Morisawa, M., Shiba, K., Cejko, B.I., and Glogowski, J.
  • Organizer: Aquaculture Europe 08
  • Place of Presentation: Krakow, Poland
• [Presentation] ホヤ精子走化性実測データに基づく精子誘引物質感知機構のシミュレーション解析 (2008)
  • Author(s): 柴小菊, 宮代大輔, 上村慎治, 吉田学
  • Organizer: 日本生物物理学会第46回年会
  • Place of Presentation: 福岡
• [Presentation] Valosin containing protein VCP/p97 binds to the sperm attractant SAAF and may control its release from the ascidian egg. (2008)
  • Author(s): Kondoh, E. 他5名
  • Organizer: 41st Society for the Study of Reproduction Annual Meeting
  • Place of Presentation: Kailua-Kona, HI, USA
• [Presentation] Ca2+ Dynamics and Chemotactic Behavior of the Ascidian Sperm (2008)
  • Author(s): Yoshida, M. 他2名
  • Organizer: 41st Society for the Study of Reproduction Annual Meeting
  • Place of Presentation: Kailua-Kona, HI, USA
• [Presentation] 精嚢分泌タンパク質semenogelinの精子膜電位および膜透過性への影響 (2008)
  • Author(s): 吉田薫 他6名
  • Organizer: 日本アンドロロジー学会第27回学術集会
  • Place of Presentation: 京都市
• [Presentation] How to Track Spermatozoa using High-Speed Visual Feedback. (2008)
  • Author(s): Oku, H, 他4名
  • Organizer: 30th Annual International Conference of the IEEE Engineering in Medicine and Biology Society
  • Place of Presentation: Vancouver, British Columbia, Canada
• [Presentation] カタユウレイボヤ精子の誘引物質濃度変化感知機構 (2008)
  • Author(s): 柴小菊 他2名
  • Organizer: 日本動物学会第79回大会
  • Place of Presentation: 福岡市
• [Presentation] カタユウレイボヤ精子走化性運動における精子内Ca2+濃度の制御機構 (2008)
  • Author(s): 丸山虎轍 他2名
  • Organizer: 日本動物学会第79回大会
  • Place of Presentation: 福岡市
• [Presentation] メダカの生殖におけるCOX阻害剤の効果 (2008)
  • Author(s): R. K. Kowalski 他1名
  • Organizer: 日本動物学会第79回大会
  • Place of Presentation: 福岡市
• [Presentation] イトマキヒトデAsterina pectinifera精子の運動開始機構 (2008)
  • Author(s): 荒木直也 他2名
  • Organizer: 日本動物学会第79回大会
  • Place of Presentation: 福岡市
• [Presentation] ホヤ精子走化性実測データに基づく精子誘引物質感知機構のシミュレーション解析 (2008)
  • Author(s): 柴小菊 他3名
  • Organizer: 日本生物物理学会第46回年会
  • Place of Presentation: 福岡市
• [Presentation] 海産無脊椎動物の精子運動と受精 (2007)
  • Author(s): 吉田学
  • Organizer: 第2回東京大学の海研究シンポジウム「海から未来を考える」
  • Place of Presentation: 東京
  • Year and Date: 2007-07-04
• [Presentation] 高速ビジュアルフィードバックを用いたホヤ精子のトラッキング (2007)
  • Author(s): 尾川順子, 石川貴彦, 奥 寛雅, 柴小菊, 吉田学, 石川正俊
  • Organizer: 日本機械学会ロボティクス・メカトロニクス講演会2007
  • Place of Presentation: 秋田
• [Presentation] ヒト精嚢分泌タンパク質Semenogelinがswim-up後の精子運動に及ぼす影響 (2007)
  • Author(s): 吉田 薫、吉池美紀、野澤資亜利、岩本晃明
  • Organizer: 日本アンドロロジー学会第26回学術大会
  • Place of Presentation: 浦安
• [Presentation] Na^+/Ca^<2+> exchanger modulates the flagellar wave pattern for the regulation of motility activation and chemotaxis in the ascidian spermatozoa (2007)
  • Author(s): Yoshida, M.
  • Organizer: Gordon Research Conference : Fertilization and the Activation of Development
  • Place of Presentation: Plymouth, NH, USA
• [Presentation] Sperm chemotactic behavior regulated by intracellular Ca^<2+> changes in the ascidian, Ciona intestinalis (2007)
  • Author(s): Shiba K, Baba, S.A., and Yoshida, M.
  • Organizer: Gordon Research Conference : Fertilization and the Activation of Development
  • Place of Presentation: Plymouth, NH, USA
• [Presentation] Semen coagulating protein, SVS2, in mouse seminal plasma controls sperm fertility (2007)
  • Author(s): Kawano, N., Yoshida, K., and Yoshida, M.
  • Organizer: Gordon Research Conference : Fertilization and the Activation of Development
  • Place of Presentation: Plymouth, NH, USA
• [Presentation] 精漿タンパク質における無精子症マーカー探索 (2007)
  • Author(s): 吉田薫, 山川克典, 西川裕之, 加藤智啓, 岩本晃明
  • Organizer: 日本ヒトプロテオーム機構第5回大会
  • Place of Presentation: 東京
• [Presentation] ホヤ精子の運動調節機構 (2007)
  • Author(s): 吉田学
  • Organizer: 東大海洋研シンポジウム「三陸と海 : その魅力と生物学」
  • Place of Presentation: 大槌
• [Presentation] Prostaglandins in rainbow trout (Oncorhynchus mykiss WALBAUM, 1792) sperm biology-seraching for answer (2007)
  • Author(s): Kowalski, R.K., Yoshida, M., Shiba, K., and Glogowski, J.
  • Organizer: The 1st International Workshop on the Biology of Fish Sperm
  • Place of Presentation: Vodnany, Czech Republic
• [Presentation] カタユウレイボヤ精子誘引物質の放出に関わる卵細胞膜タンパク質の探索 (2007)
  • Author(s): 近藤江里, 稲葉一男, 大石徹, 村田道雄, 吉田学
  • Organizer: 日本動物学会第78回大会
  • Place of Presentation: 弘前
• [Presentation] カタユウレイボヤ精子走化性における細胞内カルシウムと鞭毛運動制御 (2007)
  • Author(s): 柴小菊, 馬場昭次, 吉田学
  • Organizer: 日本動物学会第78回大会
  • Place of Presentation: 弘前
• [Presentation] カタユウレイボヤ精子走化性におけるNa^+/Ca^<2+>exchangerの役割 (2007)
  • Author(s): 丸山虎徹, 柴 小菊, 吉田 学
  • Organizer: 日本動物学会第78回大会
  • Place of Presentation: 弘前
• [Presentation] スジキレボヤ卵由来精子活性化誘引物質の部分精製 (2007)
  • Author(s): 平舘裕希, 吉田学, 泉水奏, 渡邊明彦, 森澤正昭
  • Organizer: 日本動物学会第78回大会
  • Place of Presentation: 弘前
• [Presentation] GFP-Calaxin を導入したトランスジェニックホヤ精子の解析 (2007)
  • Author(s): 水野克俊, 柴小菊, 笹倉靖徳, 吉田学, 稲葉一男
  • Organizer: 日本動物学会第78回大会
  • Place of Presentation: 弘前
• [Presentation] ホヤ卵受精時のCa2+オシレーションにおけるMAPK活性の必要性とサイクリンBによる調節 (2007)
  • Author(s): 泉水奏, 吉田 学, 立花和則
  • Organizer: 日本動物学会第78回大会
  • Place of Presentation: 弘前
• [Presentation] ヒト精漿タンパク質Semenogelinが精子運動に及ぼす影響 (2007)
  • Author(s): 吉田薫、吉池美紀、野澤資亜利、岩本晃明
  • Organizer: 日本動物学会第78回大会
  • Place of Presentation: 弘前
• [Presentation] 精子無力症患者における精子へのSPMIの結合性-透過型ならびに走査型電顕を用いた局在の検討- (2007)
  • Author(s): 吉池美紀、吉田薫、野澤資亜利、寺井一隆、岩本晃明
  • Organizer: 第52回日本生殖医学会
  • Place of Presentation: 秋田
• [Presentation] マウス受精能破壊因子SVS2の受容体はガングリオシドGM1である (2007)
  • Author(s): 河野菜摘子, 吉田薫, 吉田 学
  • Organizer: 第30回日本分子生物学会年会・第80回日本生化学会大会合同大会
  • Place of Presentation: 横浜
• [Presentation] カタユウレイボヤ精子走化性の解析 (2007)
  • Author(s): 吉田 学
  • Organizer: 第2回ホヤ研究集会
  • Place of Presentation: 下田市
• [Presentation] Na+/Ca2+ exchanger modulates the flagellar wave pattern for regulation of motility activation and chemotaxis in the ascidian spermatozoa (2007)
  • Author(s): Yoshida, Manabu
  • Organizer: Gordon Research Confernce:Fertilzation and the Activation of Development
  • Place of Presentation: Plymouth,NH,USA
• [Presentation] Semen coagulating protein,SVS2,in mouse seminal plasma controls sperm feitility (2007)
  • Author(s): Yoshida, Manabu, 他2名
  • Organizer: Gordon Research Conference:Fertilization and the Activation of Development
  • Place of Presentation: Plymouth,NH,USA
• [Presentation] Sperm chemotactic behavior regulated by intracellular Ca2+ changes in the ascidian,Ciona intestinalis (2007)
  • Author(s): Yoshida, Manabu, 他2名
  • Organizer: Gordon Research Conference:FertiliZation and the Activation of Development
  • Place of Presentation: Plymouth,NH,USA
• [Presentation] カタユウレイボヤ精子走化性における細胞内カルシウムと鞭毛運動制御 (2007)
  • Author(s): 柴 小菊, 他3名
  • Organizer: 日本動物学会第78回大会
  • Place of Presentation: 弘前市
• [Presentation] カタユウレイボヤ精子誘引物質の放出に関わる卵細胞膜タンパク質の探索 (2007)
  • Author(s): 近藤 江里, 他4名
  • Organizer: 日本動物学会第78回大会
  • Place of Presentation: 弘前市
• [Presentation] カタユウレイボヤ精子走化性におけるNa+/Ca2+exchangerの役割 (2007)
  • Author(s): 丸山 虎輙, 他2名
  • Organizer: 日本動物学会第78回大会
  • Place of Presentation: 弘前市
• [Presentation] スジキレボヤ卵由来精子活性化誘引物質の部分精製 (2007)
  • Author(s): 平舘 裕希, 他4名
  • Organizer: 日本動物学会第78回大会
  • Place of Presentation: 弘前市
• [Presentation] マウス受精能破壊因子SVS2の受容体はガングリオシドGM1である (2007)
  • Author(s): 吉田 薫, 他2名
  • Organizer: 第30回日本分子生物学会年会・第80回日本生化学会大会合同大会
  • Place of Presentation: 横浜市
• [Presentation] カタユウレイボヤ精子走化性における細胞内カルシウム占鞭毛運動制御 (2007)
  • Author(s): 柴 小菊, 他2名
  • Organizer: 日本動物学会第78回大会
  • Place of Presentation: 弘前市
• [Presentation] カタユウレイボヤ精子走化性の解析 (2005)
  • Author(s): 吉田学, 柴小菊, 近藤江里, 馬場昭次
  • Organizer: 第2回ホヤ研究集会
  • Place of Presentation: 下田
• [Book] in Conference Proceedings of IEEEEngineering in Medicine and Biology Society2008
  • Author(s): Oku, H., Ogawa, N., Shiba, K., Yoshida M., and Ishikawa, M.
  • Publisher: How to Track Spermatozoa using High-Speed Visual Feedback
• [Remarks]
  • URL: http://www.mmbs.s.u-tokyo.ac.jp/research/Yoshida/index.html
• [Remarks] 論文のプレスリリース(東京大学大学院理学系研究科のwebサイト内)
  • URL: http://www.s.u-tokyo.ac.jp/press/press-2008-25.html
• [Remarks] 新聞記事 「卵から遠ざかると精子、方向を転換東大が解明」日経産業新聞2008年11月19日朝刊11面
• [Remarks]
  • URL: http://www.mmbs.s.u-tokyo.ac.jp/research/Yoshida/index.html
• [Remarks] 論文のプレスリリース
  • URL: http://www.s.u-tokyo.acjp/press/press-2008-25.html