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Neural bases and rehabilitations of the disabilities after hemianopia

Research Project

Project/Area Number 19500439
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeSingle-year Grants
Section一般
Research Field Rehabilitation science/Welfare engineering
Research InstitutionTohoku University

Principal Investigator

HIRAYAMA Kazumi  Tohoku University, 保健医療学部, 教授 (00218819)

Co-Investigator(Kenkyū-buntansha) 境 信哉  北海道大学, 医学部, 准教授 (30299804)
仲泊 聡  東京慈恵会医科大学, 医学部, 講師 (40237318)
Co-Investigator(Renkei-kenkyūsha) NAKADOMARI Satoshi  国立障害者リハビリテーションセンター病院, 第二診療部, 部長 (40237318)
SAKAI Shinya  北海道大学, 大学院・保健科学研究院, 准教授 (30299804)
Project Period (FY) 2007 – 2009
Project Status Completed (Fiscal Year 2009)
Budget Amount *help
¥4,550,000 (Direct Cost: ¥3,500,000、Indirect Cost: ¥1,050,000)
Fiscal Year 2009: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2008: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2007: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
Keywordsリハビリテーション / 神経科学 / 脳・神経 / 脳神経疾患
Research Abstract

Using functional magnetic resonance imaging (fMRI), we investigated brain when healthy participants read meaningful Japanese sentences. We attempted to determine the exact location of activation in the primary visual cortex and tried to find out whether the activation was dynamically controlled in accordance with the location of next saccade or was fixed at some location in the parafovea, for each participant. The activation occurs in the parafoveal V1 of the left hemisphere, and did not change with the distance to the next goal of saccade but was fixed on the area representing about 4.5° of eccentricity.

Report

(4 results)
  • 2009 Annual Research Report   Final Research Report ( PDF )
  • 2008 Annual Research Report
  • 2007 Annual Research Report
  • Research Products

    (26 results)

All 2010 2009 2008 2007 Other

All Journal Article (22 results) (of which Peer Reviewed: 20 results) Book (4 results)

  • [Journal Article] Corticolimbic gray matter loss in Parkinson's disease without dementia.2010

    • Author(s)
      Nishio Y, Hirayama K, et al.
    • Journal Title

      European Journal of Neurology 17

      Pages: 1090-1097

    • Related Report
      2009 Final Research Report
    • Peer Reviewed
  • [Journal Article] Take-dependent V1 responses in human retinitis pigmentosa.2010

    • Author(s)
      Masuda Y, Horiguchi H, Dumoulin SO, Miyauchi S, Nakadomari S, et al.
    • Journal Title

      Invest Ophthalmol Vis Sci 51

      Pages: 5356-5364

    • Related Report
      2009 Final Research Report
    • Peer Reviewed
  • [Journal Article] Visual agnosia for line drawings and silhouettes without apparent impairment of real-object recognition : a case report.2009

    • Author(s)
      Hiraoka K, Suzuki K, Hirayama K, et al.
    • Journal Title

      Behavioural Neurology 21

      Pages: 187-192

    • Related Report
      2009 Final Research Report
    • Peer Reviewed
  • [Journal Article] Reactivation of medial temporal lobe and human V5/MT + during the retrieval of motion information : a PET study.2009

    • Author(s)
      Ueno A, Abe N, Suzuki M, Shigemune Y, Hirayama K, et al.
    • Journal Title

      Brain Research 1285

      Pages: 127-134

    • Related Report
      2009 Final Research Report
    • Peer Reviewed
  • [Journal Article] Do parkinsonian patients have trouble telling lies? The neurobiological basis of deceptive behavior.2009

    • Author(s)
      Abe N, Fujii T, Hirayama K, et al.
    • Journal Title

      Brain 132

      Pages: 1386-1395

    • Related Report
      2009 Final Research Report
    • Peer Reviewed
  • [Journal Article] Distinct patterns of regional cerebral glucose metabolism in Parkinson's disease with and without mild cognitive impairment.2009

    • Author(s)
      HosokaiY, NishioY, Hirayama K, et al.
    • Journal Title

      Movement Disorders 24

      Pages: 854-862

    • Related Report
      2009 Final Research Report
    • Peer Reviewed
  • [Journal Article] Evaluation of early state of cyanopsia with subjective color settings immediately after cataract removal surgery.2009

    • Author(s)
      Kitakawa T, Nakadomari S, et al.
    • Journal Title

      J Opt Soc Am A Opt Image Sci Vis 26

      Pages: 1375-1381

    • Related Report
      2009 Final Research Report
    • Peer Reviewed
  • [Journal Article] Two temporal channels in human V1 identified using fMRI.2009

    • Author(s)
      Horiguchi H, Nakadomari S, et al.
    • Journal Title

      Neuroimage 47

      Pages: 273-280

    • Related Report
      2009 Final Research Report
    • Peer Reviewed
  • [Journal Article] Objective perimetry using functional magnetic resonance imaging in patients with visual field loss.2009

    • Author(s)
      Furuta A, Nakadomari S, et al.
    • Journal Title

      Experimental Neurology 217

      Pages: 401-406

    • Related Report
      2009 Final Research Report
    • Peer Reviewed
  • [Journal Article] Do parkinsonian patients have trouble telling lies? The neurobiological basis of deceptive behavior.2009

    • Author(s)
      Abe N, Fujii T, Hirayama K, et al.
    • Journal Title

      Brain

      Volume: 132 Pages: 1386-1395

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Distinct patterns of regional cerebral glucose metabolism in Parkinson's disease with and without mild cognitive impairment.2009

    • Author(s)
      HosokaiY, NishioY, HirayamaK, et al.
    • Journal Title

      Movement Disorders

      Volume: 24 Pages: 854-862

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Reactivation of medial temporal lobe and human V5/MT+ during the retrieval of motion information : a PET study.2009

    • Author(s)
      Ueno A, Abe N, Suzuki M, Shigemune Y, Hirayama K, et al
    • Journal Title

      Brain Research

      Volume: 1285 Pages: 127-134

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] 健忘性軽度認知障害(amnestic MCI)と軽度アルツハイマー病患者の語列挙課題の遂行2009

    • Author(s)
      崔賢株, 目黒謙一, 平岡宏太良, 平山和美, 森悦朗
    • Journal Title

      神経心理学 1

      Pages: 57-63

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Simultaneously cooperative, but serially antagonistic : a neuropsychological study of diagonistic dyspraxia in a case of Marchiafava-Big-nami disease.2008

    • Author(s)
      Hirayama K, et al.
    • Journal Title

      Behavioural Neurology 19

      Pages: 137-144

    • Related Report
      2009 Final Research Report
    • Peer Reviewed
  • [Journal Article] Visual function of a patient with adrenoleuk odystrophy : Comparison of luminance and color contrast sensitivities.2008

    • Author(s)
      Sakai S, Hirayama K, et al.
    • Journal Title

      Brain and Development 30

      Pages: 68-72

    • Related Report
      2009 Final Research Report
    • Peer Reviewed
  • [Journal Article] V1 projection zone signals in human macular degeneration depend on task, not stimulus.2008

    • Author(s)
      Masuda Y, Dumoulin SO, Nakadomari S, et al.
    • Journal Title

      Cerebral Cortex 18

      Pages: 2483-2493

    • Related Report
      2009 Final Research Report
    • Peer Reviewed
  • [Journal Article] Simultaneously cooperative, but serially antagonistic : a neuropsychologi cal study of diagonistic dyspraxia in a case of Marchiafava-Big-nami disease2008

    • Author(s)
      Hirayama K, et.al.
    • Journal Title

      Behavioural Neurology 19

      Pages: 137-144

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Journal Article] 視覚性失認2008

    • Author(s)
      平山和美
    • Journal Title

      神経内科 supp15

      Pages: 358-367

    • NAID

      130008162624

    • Related Report
      2008 Annual Research Report
  • [Journal Article] Visual function of a patient with advanced adrenoleukodystrophy: Comparison of luminance and color contrast sensitivities.2008

    • Author(s)
      Sakai, et. al.
    • Journal Title

      Brain & Development 30

      Pages: 68-72

    • NAID

      10024137174

    • Related Report
      2007 Annual Research Report
    • Peer Reviewed
  • [Journal Article] パーキンソン病の視覚性認知障害2007

    • Author(s)
      平山和美ら
    • Journal Title

      Brain and Nerve 59

      Pages: 923-932

    • Related Report
      2007 Annual Research Report
  • [Journal Article] 軽度認知障害(MCI)における道具的ADL障害と痴呆への移行の関係:大崎-田尻プロジェクト2007

    • Author(s)
      花木りさら
    • Journal Title

      高次脳機能研究 27

      Pages: 298-308

    • Related Report
      2007 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Activation in left primary visual cortex representing parafoveal visual field during reading Japanese texts.

    • Author(s)
      Shimada Y, Hirayama K, Nakadomari S, et al.
    • Journal Title

      Brain research in print

    • Related Report
      2009 Final Research Report
    • Peer Reviewed
  • [Book] 急性期から取り組む高次脳機能リハビリテーション2010

    • Author(s)
      河村満編、平山和美, 他
    • Publisher
      メディカ出版
    • Related Report
      2009 Final Research Report
  • [Book] 脳卒中症候学2010

    • Author(s)
      田川皓一, 峰松一夫編、平山和美, 他
    • Publisher
      西村書店
    • Related Report
      2009 Final Research Report
  • [Book] 日常診療に必要な認知症症候学

    • Author(s)
      池田学編、平山和美, 島田洋一, 他
    • Publisher
      新興医学出版社(印刷中)
    • Related Report
      2009 Final Research Report
  • [Book] 脳血管障害と神経心理学

    • Author(s)
      田川皓一, 平山恵造編、平山和美, 他
    • Publisher
      医学書院(印刷中)
    • Related Report
      2009 Final Research Report

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Published: 2007-04-01   Modified: 2016-04-21  

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