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Studies on Control Methods of Biofilm Formation by Control of Bacterial Intercellular Communication Mechanism

Research Project

Project/Area Number 19510081
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeSingle-year Grants
Section一般
Research Field Environmental technology/Environmental materials
Research InstitutionUtsunomiya University

Principal Investigator

IKEDA Tsukasa  Utsunomiya University, 大学院・工学研究科, 教授 (40151295)

Project Period (FY) 2007 – 2009
Project Status Completed (Fiscal Year 2009)
Budget Amount *help
¥4,680,000 (Direct Cost: ¥3,600,000、Indirect Cost: ¥1,080,000)
Fiscal Year 2009: ¥650,000 (Direct Cost: ¥500,000、Indirect Cost: ¥150,000)
Fiscal Year 2008: ¥780,000 (Direct Cost: ¥600,000、Indirect Cost: ¥180,000)
Fiscal Year 2007: ¥3,250,000 (Direct Cost: ¥2,500,000、Indirect Cost: ¥750,000)
Keywordsバイオフィルム / バクテリア / 細胞間情報伝達機構 / クォーラムセンシング / N-アシル-L-ホモセリンラクトン / 阻害剤 / グラム陰性細菌 / 遺伝子発現制御 / バイオフィル / バイオフルム
Research Abstract

Bacterial biofilm formation is controlled by bacterial intercellular communication mechanism. Bacterial intercellular signal compound analogues were synthesized to inhibit bacterial biofilm formation. These compounds showed the inhibition effects on bacterial biofilm formation by adding bacterial culture medium.

Report

(4 results)
  • 2009 Annual Research Report   Final Research Report ( PDF )
  • 2008 Annual Research Report
  • 2007 Annual Research Report
  • Research Products

    (99 results)

All 2010 2009 2008 2007 Other

All Journal Article (36 results) (of which Peer Reviewed: 34 results) Presentation (53 results) Book (4 results) Remarks (4 results) Patent(Industrial Property Rights) (2 results)

  • [Journal Article] Novel N-acylhomoserine lactone-degrading bacteria isolated from the leaf surface of Solanum tuberosum and their quorum-quenching properties2009

    • Author(s)
      T. Morohoshi, N. Someya, T. Ikeda
    • Journal Title

      Biosci.Biotech.Biochem. 73

      Pages: 2124-2127

    • NAID

      10027546174

    • Related Report
      2009 Final Research Report
    • Peer Reviewed
  • [Journal Article] Motility and the expression of the flagellin protein FliC are negatively regulated by quorum sensing in Edwardsiella tarda2009

    • Author(s)
      T. Morohoshi, Y. Yokoyama, M. Ouchi, N. Kato, T. Ikeda
    • Journal Title

      J.Biosci.Bioeng. 108

      Pages: 314-318

    • NAID

      110007465826

    • Related Report
      2009 Final Research Report
    • Peer Reviewed
  • [Journal Article] Distribution of N-acylhomoserine lactone-producing fluorescent Pseudomonads on the phylloplane and in the rhizosphere of potato (Solanum tuberosum L.)2009

    • Author(s)
      N. Someya, T. Morohoshi, N. Okano, E. Otsu, K. Usuki, M. Sayama, H. Sekiguchi, T. Ikeda, S. Ishida
    • Journal Title

      Microb.Environ. 24

      Pages: 305-314

    • Related Report
      2009 Final Research Report
    • Peer Reviewed
  • [Journal Article] Development of a novel hydrogel to prevent bacterial infectious diseases2009

    • Author(s)
      N. Kato, A. Kobayashi, H. Motohahsi, Y. Ozonoe, T. Morohoshi, T. Ikeda
    • Journal Title

      Prog.Colloid.Polym.Sci. 136

      Pages: 155-162

    • Related Report
      2009 Final Research Report
    • Peer Reviewed
  • [Journal Article] Symbiotic degradation of polyvinyl alcohol by Novosphingobium sp. and Xanthobacter flavus2009

    • Author(s)
      D. Rong, K. Usui, T. Morohoshi, N. Kato, M. H. Zhou, T. Tkeda
    • Journal Title

      J.Environ.Biotech. 9

      Pages: 131-134

    • Related Report
      2009 Final Research Report
    • Peer Reviewed
  • [Journal Article] 生物防除の成否を左右する微生物間相互作用について-植物-病原体相互作用の理解に基づく病害制御の新視点2009

    • Author(s)
      染谷信孝, 諸星知広, 池田宰, 阿久津克己, 土屋健一
    • Journal Title

      植物感染生理談話会論文集 45

      Pages: 1-10

    • Related Report
      2009 Final Research Report
    • Peer Reviewed
  • [Journal Article] 植物および魚類におけるバイオフィルム感染症と Quorum Sensing2009

    • Author(s)
      池田宰, 諸星知広
    • Journal Title

      J.Germfree Life and Gnotobiology 39

      Pages: 25-28

    • NAID

      10025405235

    • Related Report
      2009 Final Research Report
    • Peer Reviewed
  • [Journal Article] 特集 : バイオフィルム感染症 基礎編・御病細菌および植物病菌のバイオフィルム形成能2009

    • Author(s)
      池田宰, 諸星知広
    • Journal Title

      臨床と微生物 36

      Pages: 29-33

    • Related Report
      2009 Final Research Report
  • [Journal Article] Novel N-acylhomoserine lactone-degrading bacteria isolated from the leaf surface of Solanum tuberosum and their quorum-quenching properties2009

    • Author(s)
      T.Morohoshi, N.Someya, T.Ikeda
    • Journal Title

      Biosci.Biotech.Biochem. 73

      Pages: 2124-2127

    • NAID

      10027546174

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Motility and the expression of the flagellin protein FliC are negatively regulated by quorum sensing in Edwardsiella tarda2009

    • Author(s)
      T.Morohoshi, Y.Yokoyama, M.Ouchi, N.Kato, T.Ikeda
    • Journal Title

      J.Biosci.Bioeng. 108

      Pages: 314-318

    • NAID

      110007465826

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Distribution of N-acylhomoserine lactone-producing fluorescent Pseudomonads on the phylloplane and in the rhizosphere of potato(Solanum tuberosum L.)2009

    • Author(s)
      N.Someya, T.Morohoshi, N.Okano, E.Otsu, K.Usuki, M.Sayama, H.Sekiguchi, T.Ikeda, S.Ishida
    • Journal Title

      Microb.Environ. 24

      Pages: 305-314

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Development of a novel hydrogel to prevent bacterial infectious diseases2009

    • Author(s)
      N.Kato, A.Kobayashi, H.Motohahsi, Y.Ozonoe, T.Morohoshi, T.Ikeda
    • Journal Title

      Prog.Colloid.Polym.Sci. 136

      Pages: 155-162

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Symbiotic degradation of polyvinyl alcohol by Novosphingobium sp.and Xanthobacter flavus2009

    • Author(s)
      D.Rong, K.Usui, T.Morohoshi, N.Kato, M.H.Zhou, T.Ikeda
    • Journal Title

      J.Environ.Biotech. 9

      Pages: 131-134

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] 生物防除の成否を左右する微生物間相互作用につてい-植物-病原体相互作用の理解に基づく病害制御の新視点2009

    • Author(s)
      染谷信孝、諸星知広、池田宰、阿久津克己、土屋健一
    • Journal Title

      植物感染生理談話会論文集 45

      Pages: 1-10

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] 植物および魚類におけるバイオフィルム感染症とQuorum Sensing2009

    • Author(s)
      池田宰、諸星知広
    • Journal Title

      J.Germfree Life snd Gnotobiology 39

      Pages: 25-28

    • NAID

      10025405235

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] 特集:バイオフィルム感染症基礎編・御病細菌および植物病菌のバイオフィルム形成能2009

    • Author(s)
      池田宰、諸星知広
    • Journal Title

      臨床と微生物 36

      Pages: 29-33

    • Related Report
      2009 Annual Research Report
  • [Journal Article] Identification and characterization of N-acylhomoserine lactone-acylase from the fish intestinal Shewanella sp. strain MIB0152008

    • Author(s)
      T. Morohoshi, S. Nakazawa, A. Ebata, N. Kato, T. Ikeda
    • Journal Title

      Biosci.Biotech.Biochem. 72

      Pages: 1887-1893

    • NAID

      10027530204

    • Related Report
      2009 Final Research Report
    • Peer Reviewed
  • [Journal Article] N-Acylhomoserine lactone regulates violacein production in Chromobacterium violaceum type strain ATCC 124722008

    • Author(s)
      T. Morohoshi, M. Kato, K. Fukamachi, N. Kato, T. Ikeda
    • Journal Title

      FEMS Microbiol.Lett. 279

      Pages: 124-130

    • Related Report
      2009 Final Research Report
    • Peer Reviewed
  • [Journal Article] Inhibition of Lux quorum-sensing system by synthetic A-acyl-L-homoserine lactone analogous2008

    • Author(s)
      W. Wang, T. Morohoshi, T. Ikeda L. Chen
    • Journal Title

      Acta Biochim.Biophys.Sin. 40

      Pages: 1023-1028

    • Related Report
      2009 Final Research Report
    • Peer Reviewed
  • [Journal Article] Detection of Pseudomonas aeruginosa quorum sensing signals in an infected ischemic wound : An experimantal study in rats2008

    • Author(s)
      G. Nakagami, H. Sanada, J. Sugama, T. Morohoshi, T. Ikeda, Y. Ohta
    • Journal Title

      Wound Repair Regen. 16

      Pages: 30-36

    • Related Report
      2009 Final Research Report
    • Peer Reviewed
  • [Journal Article] The function of SpnR and the inhibitory effects by halogenated furanone on quorum sensing in Serratia marcescens AS-12008

    • Author(s)
      Y. Tao, T. Morohoshi, N. Kato, T. Ikeda, H. Zhuang
    • Journal Title

      Acta Microbiol.Sin. 48

      Pages: 391-397

    • Related Report
      2009 Final Research Report
    • Peer Reviewed
  • [Journal Article] Artificial control of the bacterial cell-to-cell communication with autoinducer recognition gel2008

    • Author(s)
      N. Kato, Y. Ozonoe, E. Umebayashi, T. Morohoshi, T. Ikeda
    • Journal Title

      Adv.Sci.Tech. 57

      Pages: 94-98

    • Related Report
      2009 Final Research Report
    • Peer Reviewed
  • [Journal Article] Identification and characterization of N-acylhomoserine lactone-acylase from the fish intestinal Shewanella sp. strain MIB0152008

    • Author(s)
      T. Morohoshi, S. Nakazawa, A. Ebata, N. Kato, and T. Ikeda
    • Journal Title

      Biosci. Biotech. Biochem. 72

      Pages: 1887-1893

    • NAID

      10027530204

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Journal Article] N-Acylhomoserine lactorie regulates violacein production in Chromobacterium violaceum type strain ATCC 124722008

    • Author(s)
      T. Morohoshi, M. Kato, K. Fukamachi, N. Kato, and T. Ikeda
    • Journal Title

      FEMS Microbiol. Lett. 279

      Pages: 124-130

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Inhibition of Lux quorum-sensing system by synthetic N-acyl-L-homoserine lactone analogous.2008

    • Author(s)
      W. Wang, T. Morohoshi, T. Ikeda, and L. Chen
    • Journal Title

      Acta Biochim. Biophys. Sin. 40

      Pages: 1023-1028

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Detection of Pseudomonas aeruginosa quorum sensing signals in an infected ischemic wound: An experimantal study in rats2008

    • Author(s)
      G. Nakagami, H. Sanada, J. Sugama, T. Morohoshi, T. Ikeda, and Y. Ohta
    • Journal Title

      Wound Repair Regen. 16

      Pages: 30-36

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Journal Article] The function of SpnR and the inhibitory effects by halogenated furanone on quorum sensing in Serratia marcescens AS-12008

    • Author(s)
      Y. Tao, T. Morohoshi, N. Kato, T. Ikeda. and H. Zhuang
    • Journal Title

      Acta Microbiol. Sin. 48

      Pages: 391-397

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Artificial control of the bacterial cell-to-cell communication with autoinducer recognition gel2008

    • Author(s)
      N. Kato, Y. Ozonoe, E. Umebayashi, T. Morohoshi, and T. Ikeda
    • Journal Title

      Adv. Sci. Tech. 57

      Pages: 94-98

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Inhibition of quorum sensing in Pseudomonas aeruginosa by N-acyl cyclopentylamides2007

    • Author(s)
      T. Tshida, T. Ikeda N. Takiguchi, A. Kuroda, H. Ohtake, J. Kato
    • Journal Title

      Appl.Environ.Microbiol. 73

      Pages: 3183-3188

    • Related Report
      2009 Final Research Report
    • Peer Reviewed
  • [Journal Article] Inhibition of quorum sensing in Serratia marcescens AS-1 by the synthetic analogs of N-acylhomoserine lactone2007

    • Author(s)
      T. Morohoshi, T. Shiono, K. Takidouchi, M. Kato, N. Kato, J. Kato, T. Ikeda
    • Journal Title

      Appl.Environ.Microbiol. 73

      Pages: 6339-6344

    • Related Report
      2009 Final Research Report
    • Peer Reviewed
  • [Journal Article] The plant pathogen Pantoea ananatis produces N-acylhomoserine lactone and causes center rot disease of onion by quorum sensing2007

    • Author(s)
      T. Morohoshi, Y. Nakamura, G. Yamazaki, A. Ishida, N. Kato, T. Ikeda
    • Journal Title

      J.Bacteriol. 189

      Pages: 8333-8338

    • Related Report
      2009 Final Research Report
    • Peer Reviewed
  • [Journal Article] Control of virulence factor expression in opportunistic pathogens using cyclodextrin immobilized gel2007

    • Author(s)
      N. Kato, T. Tanaka, S. Nakagawa, T. Morohoshi, K. Hiratani, T. Ikeda
    • Journal Title

      J.Incl.Phenom.Macro.Chem. 57

      Pages: 419-423

    • Related Report
      2009 Final Research Report
    • Peer Reviewed
  • [Journal Article] 感染虚血性創傷における細菌数とクオラムセンシングシグナルの関係2007

    • Author(s)
      仲上豪二朗, 真田弘美, 須釜淳子, 諸星知広, 池田宰
    • Journal Title

      日本褥瘡学会誌 9

      Pages: 165-170

    • Related Report
      2009 Final Research Report
    • Peer Reviewed
  • [Journal Article] Inhibition of quorum sensing in Pseudomonas aeruginosa by N-acyl cyclopentylamides2007

    • Author(s)
      T. Ishida, T. Ikeda, N. Takiguchi, A. Kuroda, H. Ohtake, J. Kato
    • Journal Title

      Appl. Environ. Microbiol. 73

      Pages: 3183-3188

    • Related Report
      2007 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Inhibition of quorum sensing in Serratia marcescens AS-1 by the synthetic analogs of N-acylhomoserine lactone2007

    • Author(s)
      T. Morohoshi, T. Shiono, K. Takidouchi, M. Kato, N. Kato, J. Kato, T. Ikeda
    • Journal Title

      Appl. Environ. Microbiol. 73

      Pages: 6339-6344

    • Related Report
      2007 Annual Research Report
    • Peer Reviewed
  • [Journal Article] The plant pathogen Pantoea ananatis produces N-acylhomoserine lactone and causes center rot disease of onion by quorum sensing2007

    • Author(s)
      T. Morohoshi, Y. Nakamura, G. Yamazaki, A. Ishida, N. Kato, T. Ikeda
    • Journal Title

      J. Bacteriol. 189

      Pages: 8333-8338

    • Related Report
      2007 Annual Research Report
    • Peer Reviewed
  • [Presentation] Quorum sensing quenching in gram-negative bacteria using synthetic AHL analogues and cyclodextrins2010

    • Author(s)
      T. Ikeda, T. Morohoshi, S. Ito, N. Kato
    • Organizer
      日本農芸化学会2009年度大会依頼講演
    • Place of Presentation
      東京大学
    • Year and Date
      2010-03-30
    • Related Report
      2009 Final Research Report
  • [Presentation] Quorum sensing quenching in gram-negative bacteria using synthetic AHL analogues and cyclodextrins2010

    • Author(s)
      T.Ikeda, T.Morohoshi, S.Ito, N.Kato
    • Organizer
      日本農芸化学会2009年度大会
    • Place of Presentation
      東京大学
    • Year and Date
      2010-03-30
    • Related Report
      2009 Annual Research Report
  • [Presentation] 魚病細菌および植物感染菌のバイオフィルム形成と Quorum Sensing2010

    • Author(s)
      池田宰, 諸星知広
    • Organizer
      第83回日本細菌学会総会シンポジウム依頼講演
    • Place of Presentation
      横浜パシフィコ
    • Year and Date
      2010-03-29
    • Related Report
      2009 Final Research Report
  • [Presentation] 魚病細菌および植物感染菌のバイオフィルム形成とQuorum Sensing2010

    • Author(s)
      池田宰、諸星知広
    • Organizer
      第83回日本細菌学会総会
    • Place of Presentation
      パシフィコ横浜
    • Year and Date
      2010-03-29
    • Related Report
      2009 Annual Research Report
  • [Presentation] 植物病原菌Pantoea ananatisの菌体外多糖生産に関わる遺伝子群の解析2010

    • Author(s)
      諸星知広、大関貴恵美、池田宰
    • Organizer
      日本農芸化学会2010年度大会
    • Place of Presentation
      東京大学
    • Year and Date
      2010-03-28
    • Related Report
      2009 Annual Research Report
  • [Presentation] Inhibition of quorum sensing in gram-negative bacteria using AHL analogues and modified cyclodextrins2009

    • Author(s)
      T. Ikeda W. Z. Wang, T. Sato, S. Ito, N. Kato, T. Morohoshi
    • Organizer
      Asia Pacific Biochemical Engineering Conference 2009
    • Place of Presentation
      神戸国際会議場
    • Year and Date
      2009-11-26
    • Related Report
      2009 Annual Research Report 2009 Final Research Report
  • [Presentation] 大腸菌リン酸輸送系多重変異株を用いたリン酸輸送遺伝子の網羅的スクリーニング2009

    • Author(s)
      柴田泰宏、諸星知広、池田宰
    • Organizer
      第25回日本微生物生態学会大会
    • Place of Presentation
      広島大学
    • Year and Date
      2009-11-23
    • Related Report
      2009 Annual Research Report
  • [Presentation] 食虫植物ウツボカズラ消化液内共生細菌メタゲノムライブラリーの作成と有用遺伝子のスクリーニング2009

    • Author(s)
      佐藤祥子、及川学、諸星知広、池田宰
    • Organizer
      第25回日本微生物生態学会大会
    • Place of Presentation
      広島大学
    • Year and Date
      2009-11-23
    • Related Report
      2009 Annual Research Report
  • [Presentation] バレイショ葉面からのアシル化ホモセリンラクトン分解細菌の単離と分解機構の解析2009

    • Author(s)
      諸星知広、王文昭、池野谷仁、染谷信孝、池田宰
    • Organizer
      第25回日本微生物生態学会大会
    • Place of Presentation
      広島大学
    • Year and Date
      2009-11-23
    • Related Report
      2009 Annual Research Report
  • [Presentation] Quorum Sensing 制御に基づくバイオフィルム形成抑制2009

    • Author(s)
      池田宰, 諸星知広
    • Organizer
      日本生物工学会2009年度大会シンポジウム依頼講演
    • Place of Presentation
      名古屋大学
    • Year and Date
      2009-09-25
    • Related Report
      2009 Final Research Report
  • [Presentation] Quorum Sensing制御に基づくバイオフィルム形成抑制2009

    • Author(s)
      池田宰、諸星知広
    • Organizer
      日本生物工学会2009年度大会
    • Place of Presentation
      名古屋大学
    • Year and Date
      2009-09-25
    • Related Report
      2009 Annual Research Report
  • [Presentation] バレイショ葉面単離菌によるアシル化ホモセリンラクトン分解機構の解析2009

    • Author(s)
      池野谷仁、王文昭、諸星知広、染谷信孝、池田宰
    • Organizer
      日本生物工学会2009年度大会
    • Place of Presentation
      名古屋大学
    • Year and Date
      2009-09-24
    • Related Report
      2009 Annual Research Report
  • [Presentation] 植物病原菌Pantoea ananatisのクオラムセンシングによる菌体外多糖生産制御機構の解析2009

    • Author(s)
      大関貴恵美、諸星知広、池田宰
    • Organizer
      日本生物工学会2009年度大会
    • Place of Presentation
      名古屋大学
    • Year and Date
      2009-09-24
    • Related Report
      2009 Annual Research Report
  • [Presentation] Quorum Sensing とバイオフィルム形成2009

    • Author(s)
      池田宰, 諸星知広
    • Organizer
      日本防菌防黴学会第36回年次大会招待講演
    • Place of Presentation
      千里ライフサイエンスセンター
    • Year and Date
      2009-09-15
    • Related Report
      2009 Final Research Report
  • [Presentation] Quorum Sensingとバイオフィルム形成2009

    • Author(s)
      池田宰、諸星知広
    • Organizer
      日本防菌防黴学会第36回年次大会
    • Place of Presentation
      千里ライフサイエンスセンター
    • Year and Date
      2009-09-15
    • Related Report
      2009 Annual Research Report
  • [Presentation] 修飾シクロデキストリンを用いたバクテリアのQuorum Sensing抑制技術の開発2009

    • Author(s)
      永山勇樹、佐藤智哉、伊藤智志、諸星知広、加藤紀弘、池田宰
    • Organizer
      第26回シクロデキストリンシンポジウム
    • Place of Presentation
      栃木県総合文化センター
    • Year and Date
      2009-09-10
    • Related Report
      2009 Annual Research Report
  • [Presentation] Identification and characterization of new type of polyvinyl alcohol degrading bacteria from activated sludge2009

    • Author(s)
      D.Rong, T.Morohoshi, M.Kojima, M.H.Zhou, T.Ikeda
    • Organizer
      環境バイオテクノロジー学会2009年度大会
    • Place of Presentation
      東京大学
    • Year and Date
      2009-06-23
    • Related Report
      2009 Annual Research Report
  • [Presentation] 魚類腸内細菌からのアシル化ホモセリンラクトン分解遺伝子のクローニングと魚病細菌制御への応用2009

    • Author(s)
      諸星知広、中澤成寿、江幡淳、加藤紀弘、池田宰
    • Organizer
      第12回マリンバイオテクノロジー学会大会
    • Place of Presentation
      早稲田大学
    • Year and Date
      2009-05-30
    • Related Report
      2009 Annual Research Report
  • [Presentation] 細菌感染症を予防するシクロデキストリン固定化ヒドロゲルの合成2009

    • Author(s)
      村井隆将、小林愛雲、本橋拓志、諸星知広、池田宰、加藤紀弘
    • Organizer
      第5回ホスト・ゲスト化学シンポジウム
    • Place of Presentation
      宇都宮大学
    • Year and Date
      2009-05-30
    • Related Report
      2009 Annual Research Report
  • [Presentation] 修飾シクロデキストリンを用いたグラム陰性細菌のQuorum Sensing阻害2009

    • Author(s)
      佐藤智哉、諸星知広、伊藤智志、加藤紀弘、池田宰
    • Organizer
      第5回ホスト・ゲスト化学シンポジウム
    • Place of Presentation
      宇都宮大学
    • Year and Date
      2009-05-30
    • Related Report
      2009 Annual Research Report
  • [Presentation] Development of cyclodextrin-immobilized hydrogels to prevent bacterial infectious diseases2009

    • Author(s)
      A.Kobayashi, H.Motohashi, Y.Ozonoe, T.Murai, T.Morohoshi, T.Ikeda, N.Kato
    • Organizer
      The 5th Asian Cyclodextrin Conference 2009
    • Place of Presentation
      釜山(韓国)
    • Year and Date
      2009-05-15
    • Related Report
      2009 Annual Research Report
  • [Presentation] Inhibition of quorum sensing in gram-negative bacteria using modified cyclodextrins2009

    • Author(s)
      T.Sato, M.Tominaga, S.Maeda, S.Ito, N.Kato, T.Morohoshi, T.Ikeda
    • Organizer
      The 5th Asian Cyclodextrin Conference 2009
    • Place of Presentation
      釜山(韓国)
    • Year and Date
      2009-05-15
    • Related Report
      2009 Annual Research Report
  • [Presentation]2009

    • Author(s)
      池田宰, 伊藤智志, 佐藤智哉, 富永みのり, 諸星知広, 加藤紀弘
    • Organizer
      化学工学会第74年会
    • Place of Presentation
      横浜国立大学
    • Year and Date
      2009-03-19
    • Related Report
      2009 Final Research Report
  • [Presentation] 魚病細菌および植物感染菌のバイオフィルム形成と Quorum Sensing およびその制御方法の開発2009

    • Author(s)
      池田宰, 諸星知広
    • Organizer
      第82回日本細菌学会依頼講演
    • Place of Presentation
      名古屋国際会議場
    • Year and Date
      2009-03-13
    • Related Report
      2009 Final Research Report
  • [Presentation] 植物および魚類におけるバイオフィルム感染症とクォーラムセンシング2009

    • Author(s)
      池田宰, 諸星知広
    • Organizer
      第42回日本無菌生物ノートバイオロジー学会総会シンポジウム依頼講演
    • Place of Presentation
      住友クラブ
    • Year and Date
      2009-01-23
    • Related Report
      2009 Final Research Report
  • [Presentation] 植物および魚類におけるバイオフィルム感染症とクォーラムセンシング2009

    • Author(s)
      池田宰,諸星知広
    • Organizer
      第42回日本無菌生物ノートバイオロジー学会総会シンポジウム
    • Place of Presentation
      住友クラブ
    • Related Report
      2008 Annual Research Report
  • [Presentation] 魚病細菌および植物感染菌のバイオフィルム形成とQuorum Sensingおよびその制御方法の開発2009

    • Author(s)
      池田宰,諸星知広
    • Organizer
      第82回日本細菌学会
    • Place of Presentation
      名古屋国際会議場
    • Related Report
      2008 Annual Research Report
  • [Presentation] 修飾シクロデキストリン類を用いたグラム陰性細菌のQuorum Sensing阻害技術に関する研究2009

    • Author(s)
      池田宰,伊藤智志,佐藤智哉,富永みのり,諸星知広,加藤紀弘
    • Organizer
      化学工学会第74年会
    • Place of Presentation
      横浜国立大学
    • Related Report
      2008 Annual Research Report
  • [Presentation] Chromobacterium violaceumを用いた新規アシル化ホモセリンラクトンレポーター株の構築と応用2009

    • Author(s)
      諸星知広,深町勝正,岡野修也,池田宰
    • Organizer
      日本農芸化学会2009度大会
    • Place of Presentation
      マリンメッセ福岡
    • Related Report
      2008 Annual Research Report
  • [Presentation] 植物病原菌Pantoea ananatisにおける菌体凝集およびバイオフィルム形成のクオラムセンシングによる制御2009

    • Author(s)
      緒方優二,諸星知広,池田宰
    • Organizer
      日本農芸化学会2009度大会
    • Place of Presentation
      マリンメッセ福岡
    • Related Report
      2008 Annual Research Report
  • [Presentation] 食虫植物ウツボカズラ消化液内共生細菌メタゲノムからの消化に関わる新規遺伝子のクローニング2009

    • Author(s)
      及川学,佐藤祥子,菊地典子,諸星知広,池田宰
    • Organizer
      日本農芸化学会2009度大会
    • Place of Presentation
      マリンメッセ福岡
    • Related Report
      2008 Annual Research Report
  • [Presentation]2008

    • Author(s)
      池田宰
    • Organizer
      第52回日本薬学会関東支部大会依頼講演
    • Place of Presentation
      東京理科大学
    • Year and Date
      2008-10-04
    • Related Report
      2009 Final Research Report
  • [Presentation] 微生物間コミュニケーションの化学的制御2008

    • Author(s)
      池田宰
    • Organizer
      第52回日本薬学会関東支部大会
    • Place of Presentation
      東京理科大学
    • Year and Date
      2008-10-04
    • Related Report
      2008 Annual Research Report
  • [Presentation] アユ腸内フローラにおける細胞間情報伝達機構の解析2008

    • Author(s)
      池田宰, 諸星知広
    • Organizer
      日本生物工学会2008度大会依頼講演
    • Place of Presentation
      東北学院大学
    • Year and Date
      2008-08-27
    • Related Report
      2009 Final Research Report
  • [Presentation] Inhibition of quorum sensing in gram-negative bacteria using cyclodextrins2008

    • Author(s)
      T. Ikeda, T. Morohoshi, N. Kato
    • Organizer
      14th International Cyclodextrin Symposium 招待講演
    • Place of Presentation
      同志社大学
    • Year and Date
      2008-05-10
    • Related Report
      2009 Final Research Report
  • [Presentation] Control of virulence gene expression due to the inclusion complex formation between immobilized cyclodextrins and bacterial auorum sensing signals2008

    • Author(s)
      Y. Ozonoe, T. Morohoshi, T. Ikeda, N. Kato
    • Organizer
      14th International Cyclodextrin Symposium
    • Place of Presentation
      Doshisha Univ
    • Related Report
      2008 Annual Research Report
  • [Presentation] Inhibition of quorum sensing in gram-negative bacteria using cyclodextrins2008

    • Author(s)
      T. Ikeda, T. Morohoshi, N. Kato
    • Organizer
      14th International Cyclodextrin Symposium
    • Place of Presentation
      Doshisha Univ
    • Related Report
      2008 Annual Research Report
  • [Presentation] 魚病細菌Edwardsiellatardaの運動性および鞭毛タンパク質発現のQuorum Sensingによる制御2008

    • Author(s)
      諸星知広,横山裕亮,加藤紀弘,池田宰
    • Organizer
      第11回マリンバィオテクノロジー学会大会
    • Place of Presentation
      京都大学
    • Related Report
      2008 Annual Research Report
  • [Presentation] Does inter-species communication via acylated homoserine lactone signals trigger infection of pressure-induced ischemic wounds by lasIrhll mutant Pseudomonas aeruginosa?2008

    • Author(s)
      G. Nakagami, H. Sanada, A. Kinoshita, T. Morohoshi, T. Ikeda; Y. Ohta, T. Nakatani, J. Sugama, M. Sakamoto, Y. Benno
    • Organizer
      The 3rd Congress of the World Union of Wound Healing Societies
    • Place of Presentation
      Toronto, Canada
    • Related Report
      2008 Annual Research Report
  • [Presentation] 新規アシル化ホモセリンラクトンレポーター株を用いた環境中の微生物間シグナリングの解析2008

    • Author(s)
      諸星知広,深町勝正,加藤正史,加藤紀弘,池田宰
    • Organizer
      環境バイオテクノロジー学会2008年度大会
    • Place of Presentation
      文部科学省研究交流センター
    • Related Report
      2008 Annual Research Report
  • [Presentation] Chromobacterium violaceumの株間における紫色色素生産のQuorum Sensingによる制御機構の比較解析2008

    • Author(s)
      深町勝正,諸星知広,加藤紀弘,池田宰
    • Organizer
      日本生物工学会2008度大会
    • Place of Presentation
      東北学院大学
    • Related Report
      2008 Annual Research Report
  • [Presentation] 植物病原菌Pantoea ananatisのQuorum sensingによる病原性発現機構の解析と阻害技術開発2008

    • Author(s)
      海野大輝,諸星知広,加藤紀弘,池田宰
    • Organizer
      日本生物工学会2008度大会
    • Place of Presentation
      東北学院大学
    • Related Report
      2008 Annual Research Report
  • [Presentation] Quorum sensingをターゲットとした植物病原菌Pantoea ananatisの衙易検出法の開発2008

    • Author(s)
      大関貴恵美,諸星知広,加藤紀弘,池田宅
    • Organizer
      日本生物工学会2008度大会
    • Place of Presentation
      東北学院大学
    • Related Report
      2008 Annual Research Report
  • [Presentation] アユ腸内フローラにおける細胞間情報伝達機構の解析2008

    • Author(s)
      池田宰,諸星知広
    • Organizer
      日本生物工学会2008度大会
    • Place of Presentation
      東北学院大学
    • Related Report
      2008 Annual Research Report
  • [Presentation] 細菌感染症予防能力を有するヒドロゲルの設計2008

    • Author(s)
      加藤紀弘,小林愛雲,本橋拓志,藷星知広,池田宰
    • Organizer
      田中豊一記念シンポジウム
    • Place of Presentation
      アルカディア市谷
    • Related Report
      2008 Annual Research Report
  • [Presentation] Inhibition of Lux quorum sensing system by synthetic AHL analogous and cvclodextrins2008

    • Author(s)
      W. Z. Wang, T. Morohoshi, T. Ikeda
    • Organizer
      第3回バイオ関連化学合同シンポジウム
    • Place of Presentation
      東京工業大学
    • Related Report
      2008 Annual Research Report
  • [Presentation] シクロデキストリン固定化ヒドロゲルを用いるセラチア菌のクオーラムセンシング制御2008

    • Author(s)
      本橋拓志,小林愛雲,小園江ゆう,諸星知広,池田宰,加藤紀弘
    • Organizer
      第57回高分子討論会
    • Place of Presentation
      大阪市立大学
    • Related Report
      2008 Annual Research Report
  • [Presentation] オートインデ丘ーサー認識ゲルを用いる日和見感染菌の遺伝子発現制御2008

    • Author(s)
      加藤紀弘,池田宰,諸星知広,小園江ゆう,本橋拓志,小林愛雲
    • Organizer
      第57回高分子討論会
    • Place of Presentation
      大阪市立大学
    • Related Report
      2008 Annual Research Report
  • [Presentation] Fast responsive organic-inorganic hydrogel prepared by temperature-induced phase separation2008

    • Author(s)
      K. Suguro, H. Motohashi, T. Morohoshi, T. Ikeda, K. Iimura, N. Kato
    • Organizer
      The IUMRS Interational Conference in Asia 2008
    • Place of Presentation
      Nagoya
    • Related Report
      2008 Annual Research Report
  • [Presentation] Regulation of bacterial cell-cell communication with autoinducer recognitiongel2008

    • Author(s)
      N.Kato,A.Kobayashi,Y.Ozonoe,H. Motohashi,T.Morohoshi,T.Ikeda
    • Organizer
      The IUMRS Interational Conference in Asia 2008
    • Place of Presentation
      Naaova
    • Related Report
      2008 Annual Research Report
  • [Presentation] アユ腸内細菌由来アシル化ホモセリンラクトン分解酵素によるバイオフィルム形成阻害2007

    • Author(s)
      池田宰, 諸星知広, 中澤成寿, 加藤紀弘
    • Organizer
      Bacterial Adherence & Biofilm 第21回学術集会依頼講演
    • Place of Presentation
      東邦大学
    • Year and Date
      2007-07-07
    • Related Report
      2009 Final Research Report
  • [Presentation] アユ腸内細菌由来アシル化ホモセリンラクトン分解酵素によるバイオフィルム形成阻害2007

    • Author(s)
      池田 宰, 諸星知広, 中澤成寿, 加藤紀弘
    • Organizer
      Bacterial Adherence&Biofilm 第21回学術集会
    • Place of Presentation
      グランドプリンスホテル新高輪
    • Year and Date
      2007-07-07
    • Related Report
      2007 Annual Research Report
  • [Presentation] アユ腸内共生細菌における Quorum Sensing シグナリングの解析2007

    • Author(s)
      池田宰, 諸星知広, 江幡淳, 中澤成寿, 加藤紀弘
    • Organizer
      環境バイオテクノロジー学会2007年度大会
    • Place of Presentation
      大阪大学
    • Year and Date
      2007-06-27
    • Related Report
      2009 Final Research Report
  • [Book] 自己組織化ハンドブック第1編第1章第1節5. 分子認識系2009

    • Author(s)
      小宮山真, 池田宰(分担)
    • Publisher
      NTS
    • Related Report
      2009 Final Research Report
  • [Book] 自己組織化ハンドブック第1編第1章第1節5.分子認識系2009

    • Author(s)
      小宮山真、池田宰(分担)
    • Total Pages
      937
    • Publisher
      NTS
    • Related Report
      2009 Annual Research Report
  • [Book] バイオフィルムの基礎と制御、第1編第1章第2節「微生物間コミュニケーション (クオラムセンシング)」2008

    • Author(s)
      諸星知広, 加藤紀弘, 池田宰 (分担)
    • Publisher
      NTS
    • Related Report
      2009 Final Research Report
  • [Book] バイオフィルムの基礎と制御第1編第1章第2節「微生物間コミュニケーション(クオラムセンシング)」2008

    • Author(s)
      諸星知広,加藤紀弘,池田宰(分担)
    • Total Pages
      300
    • Publisher
      エヌ・ティー・エス
    • Related Report
      2008 Annual Research Report
  • [Remarks] ホームページ等

    • URL

      http://www.chem.utsunomiya-u.ac.jp/lab/bio/

    • Related Report
      2009 Final Research Report
  • [Remarks]

    • URL

      http://www.chem.utsunomiya-u.ac.jp/lab/bio/

    • Related Report
      2009 Annual Research Report
  • [Remarks]

    • URL

      http://www.chem.utsunomiya-u.acjp/lab/bio/

    • Related Report
      2008 Annual Research Report
  • [Remarks]

    • URL

      http://www.chem.utsunomiya-u.ac.jp/lab/bio/

    • Related Report
      2007 Annual Research Report
  • [Patent(Industrial Property Rights)] シクロデキストリン誘導体、シクロデキストリン誘導体の製造方法、及びクオラムセンシングの阻害方法2008

    • Inventor(s)
      伊藤智志, 諸星知広, 池田宰, 加藤紀弘
    • Industrial Property Rights Holder
      宇都宮大学
    • Industrial Property Number
      2008-135674
    • Filing Date
      2008-05-23
    • Related Report
      2009 Final Research Report
  • [Patent(Industrial Property Rights)] シクロデキストリン誘導体、シクロデキストリン誘導体の製造方法、及びクオラムセンシングの阻害方法2008

    • Inventor(s)
      伊藤智志、諸星知広,池田宰、加藤紀弘
    • Industrial Property Rights Holder
      宇都宮大学
    • Industrial Property Number
      2008-135674
    • Filing Date
      2008-05-23
    • Related Report
      2008 Annual Research Report

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Published: 2007-04-01   Modified: 2016-04-21  

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