Functional analysis of a gibberellin receptor, GID1

• Project/Area Number: 19570037
• Research Category: Grant-in-Aid for Scientific Research (C)
• Allocation Type: Single-year Grants
• Section: 一般
• Research Field: 植物生理・分子
• Research Institution: Nagoya University
• Principal Investigator: UEGUCHI Miyako Nagoya University, 生物機能開発利用研究センター, 准教授 (70377795)
• Project Period (FY): 2007 – 2008
• Project Status: Completed (Fiscal Year 2008)
• Budget Amount: ¥4,680,000 (Direct Cost: ¥3,600,000、Indirect Cost: ¥1,080,000); Fiscal Year 2008: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000); Fiscal Year 2007: ¥3,120,000 (Direct Cost: ¥2,400,000、Indirect Cost: ¥720,000)
• Keywords: 植物分子 / 植物ホルモン / 受容体 / ジベレリン / シグナル伝達

Research Abstract

ジベレリン(GA)受容体は、ジベレリンと結合すると抑制因子であるDELLAタンパク質(SLR1)と結合しSLR1を分解し、脱抑制させることがわかっている。本課題では、受容体とGAとの結合、SLR1との結合に関して、構造解析(X線構造解析)、in vitro、in vivoのレベルで解析を行い、その分子メカニズムを明らかにした。

Research Products

• [Journal Article] Structural basis for gibberellin recognition by its receptor GID1 (2008)
  • Author(s): Shimada A, Ueguchi-Tanaka M., Nakatsu T, Nakajima M, Naoe Y, Ohmiya H, Kato H, Matsuoka M.
  • Journal Title: Nature 456 Pages: 520-523
  • Peer Reviewed
• [Journal Article] Release of the repressive activity of rice DELLA protein SLR1 by gibberellin does not require SLR1 degradation in the gid2 mutant (2008)
  • Author(s): Ueguchi-Tanaka M., Hirano K, Hasegawa Y, Kitano H, Matsuoka M.
  • Journal Title: Plant Cell 20 Pages: 2437-2446
  • Peer Reviewed
• [Journal Article] Comprehensive transcriptome analysis of phytohormone biosynthesis and signaling genes in microspore/pollen and tapetum of rice (2008)
  • Author(s): Hirano K, Aya K, Hobo T, Sakakibara H, Kojima M, Shim RA, Hasegawa Y, Ueguchi-Tanaka M., Matsuoka M.
  • Journal Title: Plant Cell Physiol 49 Pages: 1429-1450
  • Peer Reviewed
• [Journal Article] Functional analysis of cotton orthologs of GA signal transduction factors GID1 and SLR1 (2008)
  • Author(s): Aleman L, Kitamura J, Abdel-mageed H, Lee J, Sun Y, Nakajima M, Ueguchi-Tanaka M., Matsuoka M, Allen RD.
  • Journal Title: Plant Mol Biol 68 Pages: 1-16
  • Peer Reviewed
• [Journal Article] GID1-mediated gibberellin signaling in plants (2008)
  • Author(s): Hirano K, Ueguchi-Tanaka M., Matsuoka M.
  • Journal Title: Trends Plant Sci. Pages: 192-199
  • Peer Reviewed
• [Journal Article] Functional analysis of cotton orthologs of GA signal transduction factors GID1 and SLR1. (2008)
  • Author(s): Aleman L.
  • Journal Title: Plant Mol Biol. 68 Pages: 1-16
  • Peer Reviewed
• [Journal Article] Comprehensive transcriptome analysis of phytohormone biosynthesis and signaling genes in microspore/pollen and tapetum of rice. (2008)
  • Author(s): Hirano K
  • Journal Title: Plant Cell Physiol. 49 Pages: 1429-1450
  • Peer Reviewed
• [Journal Article] Release of the repressive activity of rice DELLA protein SLR1 by gibberellin does not require SLR1 degradation in the gid2 mutant. (2008)
  • Author(s): Ueguchi-Tanaka M.
  • Journal Title: Plant Cell 20 Pages: 2437-2446
  • Peer Reviewed
• [Journal Article] Structural basis for gibberellin recognition by its receptor GID1. (2008)
  • Author(s): Shimada A.
  • Journal Title: Nature 456 Pages: 520-523
  • Peer Reviewed
• [Journal Article] GID1-mediated gibberellin signaling in plants. (2008)
  • Author(s): Hirano K.
  • Journal Title: Trends Plant Sci. 13 Pages: 192-199
  • Peer Reviewed
• [Journal Article] ジベレリンシグナル伝達の分子機構とその進化 (2008)
  • Author(s): 平野 恒
  • Journal Title: 遺伝 62 Pages: 30-34
• [Journal Article] ジベレリン受容体 (2007)
  • Author(s): 上口(田中)美弥子、中嶋正敏、松岡信
  • Journal Title: 植物の生長調節 42, (1) Pages: 30-36
  • Peer Reviewed
• [Journal Article] Gibberellin receptor and its role in gibberellin signaling in plants (2007)
  • Author(s): Ueguchi-Tanaka, M., Nakajima, M., Ashikari, M., Matsuoka, M.
  • Journal Title: Annu. Rev. Plant Biol 58 Pages: 183-198
  • Peer Reviewed
• [Journal Article] Gibberellin regulates pollen viability and pollen tube growth in rice (2007)
  • Author(s): Chhun, T., Aya, K., Asano, K., Yamamoto, E., Morinaka, Y. Watanabe, M., Kitano, H., Ashikari, M., Matsuoka, M., Ueguchi-Tanaka, M
  • Journal Title: Plant Cell 19 Pages: 3876-3888
  • Peer Reviewed
• [Journal Article] The GID1-mediated gibberellin perception mechanism is conserved in the Lycophyte Selaginella moellendorffii but not in the Bryophyte Physcomitrella patens (2007)
  • Author(s): Hirano, K., Nakajima, M., Asano, K., Nishiyama, T., Sakakibara, H., Kojima, M., Katoh, E., Xiang, H., Tanahashi, T., Hasebe, M., Banks, J.A., Ashikari, M., Kitano, H., Ueguchi-Tanaka, M., Matsuoka, M.
  • Journal Title: Plant Cell 19 Pages: 3058-3079
  • Peer Reviewed
• [Journal Article] Molecular interactions of a soluble gibberellin receptor, GID1, with a rice DELLA protein, SLR1 and gibberellin (2007)
  • Author(s): Ueguchi-Tanaka, M., Nakajima, M., Katoh, E., Ohiya, H., Asano, K., Saji, S., Hongyu, X., Ashikari, M., Kitano H., Yamaguchi, I., Matsuoka, M
  • Journal Title: Plant Cell 19 Pages: 2140-2155
  • Peer Reviewed
• [Journal Article] Multiple loss-of-function of Arabidopsis gibberellin receptor AtGID1s completely shuts down a gibberellin signal (2007)
  • Author(s): Iuchi, S. Suzuki, H., Kim, Y.C., Iuchi, A., Kuromori, T., Ueguchi-Tanaka, M., Asami, T., Yamaguchi, I., Matsuoka, M., Kobayashi, M., Nakajima, M.
  • Journal Title: Plant J 50 Pages: 958-966
  • Peer Reviewed
• [Journal Article] Multiple loss-of-function of Arabidopsis gibberellin receptor AtGIDls completely shuts down a gibberellin signal. (2007)
  • Author(s): Iuchi, S.
  • Journal Title: Plant J. 50 Pages: 958-966
  • Peer Reviewed
• [Journal Article] Molecular interactions of a soluble gibberellin receptor, GID1, with a rice DELLA protein, SLR1 and gibberellin. (2007)
  • Author(s): Ueguchi-Tanaka, M.
  • Journal Title: Plant Cell 19 Pages: 2140-2155
  • Peer Reviewed
• [Journal Article] The GID1-mediated gibberellin perception mechanism is conserved in the Lycophyte Selaginella moellendorffii but not in the Bryophyte Physcomitrella patens. (2007)
  • Author(s): Hirano, K.
  • Journal Title: Plant Cell 19 Pages: 3058-3079
  • Peer Reviewed
• [Journal Article] Gibberellin regulates pollen viability and pollen tube growth in rice. (2007)
  • Author(s): Chhun, T.
  • Journal Title: Plant Cell 19 Pages: 3876-3888
  • Peer Reviewed
• [Presentation] gid2変異体におけるSLR1タンパク質分解を伴わないGAシグナルの脱抑制 (2009)
  • Author(s): 上口(田中)美弥子、平野恒、長谷川慶子、北野英己、松岡信
  • Organizer: 第50回日本植物生理学会年会
  • Place of Presentation: 名古屋
  • Year and Date: 2009-03-22
• [Presentation] イネのジベレリンシグナル伝達の初期過程にかかわるGID1, SLR1, GID2の相互作用 (2009)
  • Author(s): 平野恒、辻寛之、上口(田中)美弥子、松岡信
  • Organizer: 第50回日本植物生理学会年会
  • Place of Presentation: 名古屋
  • Year and Date: 2009-03-22
• [Presentation] ジベレリン受容体の立体構造を基にした分子進化と基質特異性の解析 (2009)
  • Author(s): 島田麻子、上口(田中)美弥子、中津亨、中嶋正敏、直江洋一、大宮博子、加藤博章、松岡信
  • Organizer: 第50回日本植物生理学会年会
  • Place of Presentation: 名古屋
  • Year and Date: 2009-03-22
• [Presentation] gid2変異体におけるSLR1 タンパク質分解を伴わないGAシグナルの脱抑制 (2009)
  • Author(s): 上口(田中)美弥子
  • Organizer: 第50回日本植物生理学会年会
  • Place of Presentation: 名古屋
  • Year and Date: 2009-03-22
• [Presentation] Structural analysis of gibberellin receptor, GID1 (2008)
  • Author(s): Ueguchi-Tanaka, M.
  • Organizer: 11th Swiss-Japanese Joint Meeting on Biotechnology and Bioprocess Development
  • Place of Presentation: Minusio, Switzerland
• [Presentation] A soluble gibberellin receptor, GID1, and early gibberellin signal transduction (2007)
  • Author(s): Makoto, M., Hirano, K. and Ueguchi-Tanaka, M
  • Organizer: 第30回日本分子生物学会年会
  • Place of Presentation: 神奈川
  • Year and Date: 2007-12-09
• [Presentation] イネ半優性矮性変異体Slr1-dの遺伝学解析 (2007)
  • Author(s): 浅野賢治、平野恒、上口(田中)美弥子、香村敏郎、佐藤光、北野英己、松岡信、芦苅基行
  • Organizer: 日本育種学会第112回講演会
  • Place of Presentation: 山形
  • Year and Date: 2007-09-22
• [Presentation] MOLECULAR INTERACTIONS OF A SOLUBLE GIBBERELLIN RECEPTOR, GID1, WITH A RICE DELLA PROTEIN, SLR1, AND GIBBERELLIN (2007)
  • Author(s): Ueguchi-Tanaka, M.
  • Organizer: 19th International Conference on Plant Growth Substances
  • Place of Presentation: Mexico
  • Year and Date: 2007-07-24
• [Presentation] GIBBERELLIN PERCEPTION AND SIGNAL TRANSDUCTION (2007)
  • Author(s): Ueguchi-Tanaka, M.
  • Organizer: 19th International Conference on Plant Growth Substances
  • Place of Presentation: Mexico
  • Year and Date: 2007-07-22
• [Presentation] GAMYB PLAYS IMPORTANT ROLE IN POLLEN DEVELOPMENT AS A MEMBER OF GA SIGNALING (2007)
  • Author(s): Aya, K.
  • Organizer: 19th International Conference on Plant Growth Substances
  • Place of Presentation: Mexico
  • Year and Date: 2007-07-22
• [Presentation] GIBBERELLIN INSENSITIVE DWARF1 (GID1) encodes a soluble GA receptor that shares sequence similarity with a hormone sensitive lipase (HSL) (2007)
  • Author(s): Ueguchi-Tanaka, M.
  • Organizer: 14th Japanese-German Workshop on Enzyme Technology
  • Place of Presentation: Kanazawa, Japan
• [Presentation] MOLECULAR INTERACTIONS OF A SOLUBLE GIBBERELLIN RECEPTOR, GID1, WITH A RICE DELLA PROTEIN, SLR1, AND GIBBERELLIN (2007)
  • Author(s): Ueguchi-Tanaka, M., Nakajima, M., Katoh, E., Ohmiya, H., Asano, K., Saji, S., Hongyu, X., Ashikari, M., Kitano, H., Yamaguchi, I., and Matsuoka, M.
  • Organizer: 19^<th> IPGSA Meeting
  • Place of Presentation: Puerto Vallarta, Mexico
• [Presentation] Gibberellin perception and signal transduction in rice (2007)
  • Author(s): Ueguchi-Tanaka, M., Nakajima, M., Ashikari, M., Matsuoka, M.
  • Organizer: 19^<th> IPGSA Meeting
  • Place of Presentation: Puerto Vallarta, Mexico
• [Presentation] GIBBERELLIN INSENSITIVE DWARF1 (GID1), a soluble gibberellin receptor in rice (2007)
  • Author(s): Matsuoka, M., Ueguchi-Tanaka, M.
  • Organizer: The 18th International Conference on Arabidopsis Research
  • Place of Presentation: Beijing, CHINA
• [Book] Molecular biology of gibberellins signaling in higher plants (2008)
  • Author(s): Itoh H, Ueguchi-Tanaka M., Matsuoka M.
  • Publisher: Int. Rev. Cell Mol. Biol
• [Book] Int. Rev. Cell Mol. Biol. (2008)
  • Author(s): Itoh H.
  • Publisher: Molecular biology of gibberellins signaling in higher plants.