Development of novel synthesis reactions based on radicals
| Project/Area Number |
19590005
|
|---|
| Research Category |
Grant-in-Aid for Scientific Research (C)
|
| Allocation Type | Single-year Grants |
|---|
| Section | 一般 |
|---|
| Research Field |
Chemical pharmacy
|
|---|
| Research Institution | Hyogo University of Health Sciences |
|---|
Principal Investigator |
MIYABE Hideto Hyogo University of Health Sciences, 薬学部, 教授 (10289035)
|
|---|
| Co-Investigator(Kenkyū-buntansha) |
KOHTANI Shigeru 兵庫医療大学, 薬学部, 講師 (00242529)
|
|---|
| Project Period (FY) |
2007 – 2009
|
| Project Status |
Completed (Fiscal Year 2009)
|
| Budget Amount *help |
¥4,030,000 (Direct Cost: ¥3,100,000、Indirect Cost: ¥930,000)
Fiscal Year 2009: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2008: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2007: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
|
|---|
| Keywords | ラジカル / 薬学 / 有機化学 / 合成化学 / 触媒・化学プロセス / ラジカル化学 / 光触媒 |
|---|
| Research Abstract |
Strategies involving cascade process offer the advantage of multiple carbon-carbon bond formations in a single operation. At first, we developed the radical cascade reaction of substrates having two different radical acceptors. Additionally, cascade reaction involving hydroxylation with molecular oxygen was also developed. Next, several reactions using catalysts were investigated. From the standpoint of sustainable chemistry, these developed catalyst-mediated reactions would be desirable tools for preparing organic compounds.
|
Report
(5 results)
Research Products
(87 results)
