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Comparative analysis of Glycyrrhiza plants based on genotypes and chemical variations

Research Project

Project/Area Number 19590121
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeSingle-year Grants
Section一般
Research Field Environmental pharmacy
Research InstitutionIwate Medical University

Principal Investigator

HAYASHI Hiroaki  Iwate Medical University, 薬学部, 准教授 (50260998)

Project Period (FY) 2007 – 2009
Project Status Completed (Fiscal Year 2009)
Budget Amount *help
¥4,420,000 (Direct Cost: ¥3,400,000、Indirect Cost: ¥1,020,000)
Fiscal Year 2009: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2008: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2007: ¥2,080,000 (Direct Cost: ¥1,600,000、Indirect Cost: ¥480,000)
Keywords薬用資源学 / 遺伝子型 / 成分変異 / 甘草 / 成分育種 / 国際研究者交流 / 中国
Research Abstract

Comparative analysis of Glycyrrhiza plants based on the DNA sequence and chemical constituents were performed to characterize the variation of G. uralensis, which is one of the most important medicinal plants in the world. G.uralensis was divided into the two types, China-type and Kazakstan-type, based on the DNA sequences (pkr genotype) and chemical constituents in the leaves (chemotype). There was correlation between the pkr genotype and chemotype of G.uralesis. Furthermore, high glycyrrhizin-producing strains (T628 and 01A07-1) and a glycyrrhizin-deficient stain (83-555) were selected from the populations of G.uralensis.

Report

(4 results)
  • 2009 Annual Research Report   Final Research Report ( PDF )
  • 2008 Annual Research Report
  • 2007 Annual Research Report
  • Research Products

    (12 results)

All 2009 2008 2007

All Journal Article (6 results) Presentation (4 results) Book (2 results)

  • [Journal Article] Economic importance of licorice2009

    • Author(s)
      H. Hayashi, H. Sudo
    • Journal Title

      Plant Biotechnology 26

      Pages: 101-104

    • NAID

      10025181445

    • Related Report
      2009 Final Research Report
  • [Journal Article] 日局定量法を用いた簡便な甘草の基原植物推定法の検討2009

    • Author(s)
      田村, 高橋, 寺崎, 田中, 永井, 林藤井, 横田
    • Journal Title

      富山県薬事研究所年報 36

      Pages: 46-53

    • Related Report
      2009 Annual Research Report
  • [Journal Article]2009

    • Author(s)
      Hiroaki Hayashi
    • Journal Title

      Recent Advances in Plant Biotechnology, Chapter 5 Molecular Biology of Secondary Metabolism : Case Study for Glycyrrhiza Plants.(分担執筆Ed by Kirakosyan and Kaufman)(Springer)

      Pages: 89-103

    • Related Report
      2009 Annual Research Report
  • [Journal Article] カンゾウ属植物の自生地調査と系統解析2007

    • Author(s)
      林宏明
    • Journal Title

      Foods & Food Ingredients Journal of Japan 212

      Pages: 357-364

    • Related Report
      2009 Final Research Report
  • [Journal Article] Molecular biology of triterpenoid biosynthesis in Glycyrrhiza plants2007

    • Author(s)
      H. Hayashi
    • Journal Title

      Japanese Journal of Plant Science 1

      Pages: 20-24

    • Related Report
      2009 Final Research Report
  • [Journal Article] カンゾウ属植物の自生地調査と系統解析2007

    • Author(s)
      林 宏明
    • Journal Title

      Foods & Food Ingredients Journal of Japan 212

      Pages: 357-364

    • Related Report
      2007 Annual Research Report
  • [Presentation] 遺伝子配列によるカンゾウの系統解析2008

    • Author(s)
      林宏明
    • Organizer
      第4回甘草に関するシンポジウム
    • Place of Presentation
      大阪
    • Year and Date
      2008-06-28
    • Related Report
      2009 Final Research Report
  • [Presentation] Biosynthesis of triterpene saponins in intact plant of Glycyrrhiza glabra2008

    • Author(s)
      H. Hayashi
    • Organizer
      Shanghai International Synposium on Parmacy
    • Place of Presentation
      Shanghai, China
    • Related Report
      2009 Final Research Report
  • [Presentation] Comparative analysis of Glycyrrhiza uralensis2007

    • Author(s)
      H. Hayashi
    • Organizer
      Asian Symposium for Pharmaceutical Science in JSPS Asian Core Program
    • Place of Presentation
      Sasebo, Japan
    • Related Report
      2009 Final Research Report
  • [Presentation] Comparative Analysis of Glycyrrhiza uralensis2007

    • Author(s)
      Hiroaki Hayashi
    • Organizer
      Asian Symposium for Pharmaceutical Science In JSPS Asian Core Program
    • Place of Presentation
      Sasebo,Nagasaki,Japan
    • Related Report
      2007 Annual Research Report
  • [Book] Recent Advances in Plant Biotechnology(ed by A. Kirakosyan and P. B. Kaufman, Chaptor 5, Molecular biology of secondary metabolism: Case study for Glycyrrhiza plants)2009

    • Author(s)
      H. Hayashi
    • Publisher
      Springer
    • Related Report
      2009 Final Research Report
  • [Book] Analysis of Natural Glycosides"(ed by Y. Shoyama, Comparative analysis of Glycyrrhiza plants based on triterpene saponin constituents and DNA sequences)2007

    • Author(s)
      H. Hayashi
    • Publisher
      Research Signpost
    • Related Report
      2009 Final Research Report

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Published: 2007-04-01   Modified: 2016-04-21  

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