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CharaGterization of the evoked inflammation via hypoxic response in endothelial cells

Research Project

Project/Area Number 19590281
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeSingle-year Grants
Section一般
Research Field General medical chemistry
Research InstitutionThe University of Tokushima

Principal Investigator

TOMITA Tomita  The University of Tokushima, 大学院・ヘルスバイオサイエンス研究部, 准教授 (00263898)

Co-Investigator(Kenkyū-buntansha) TAMAKI Tamaki  徳島大学, 大学院・ヘルスバイオサイエンス研究部, 教授 (80179879)
Research Collaborator ISHIZAWA Ishizawa  徳島大学, 大学院・ヘルスバイオサイエンス研究部, 助教 (60398013)
URATA Urata  徳島大学, 大学院・ヘルスバイオサイエンス研究部, 大学院生
FUKUHARA Yayoi  徳島大学, 大学院・ヘルスバイオサイエンス研究部, 大学院生
Project Period (FY) 2007 – 2008
Project Status Completed (Fiscal Year 2008)
Budget Amount *help
¥4,550,000 (Direct Cost: ¥3,500,000、Indirect Cost: ¥1,050,000)
Fiscal Year 2008: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
Fiscal Year 2007: ¥2,730,000 (Direct Cost: ¥2,100,000、Indirect Cost: ¥630,000)
Keywords高次生命医学 / 血管内皮細胞 / 低酸素応答 / 炎症反応 / 転写因子 / Hypoxia Inducible Factor / 肺性高血圧 / 血管平滑筋細胞 / 炎症細胞
Research Abstract

生体が低酸素環境に曝されたときには、生体の主要な酸素供給経路に位置する血管内皮細胞(EC)は、様々な病態疾患に伴う低酸素応答の仲介役的存在であると考えられる。研究代表者らは、ECに発現する低酸素応答性転写因子ARNT遺伝子を欠失させたマウスを作製・利用することにより、生体内の炎症に細胞内低酸素応答がどのように関与するのかを解析した。その結果、ECの低酸素応答は、生体の炎症惹起に寄与している可能性が示された。

Report

(3 results)
  • 2008 Annual Research Report   Final Research Report ( PDF )
  • 2007 Annual Research Report
  • Research Products

    (66 results)

All 2009 2008 2007

All Journal Article (28 results) (of which Peer Reviewed: 22 results) Presentation (34 results) Book (4 results)

  • [Journal Article] Adiponectin inhibits insulin-like growth factor-1-induced cellmigration via the suppression of extracellular signal-regulated kinase1/2 actuation, but not Akt in vascular smooth muscle cells2009

    • Author(s)
      Motobayashi Y, Izawa-Ishizawa Y, Ishizawa K, OrinoS, Yamaguchi K, Kawazoe K, Hamann S, Tsuchiya K, Tomit S and Tamaki T
    • Journal Title

      Hypertens Res 32

      Pages: 188-193

    • Related Report
      2008 Final Research Report
    • Peer Reviewed
  • [Journal Article] Gene expression profile of third pharyngeal pouch reveals role of mesenchymal MafB in embryonic thymus develoPment2009

    • Author(s)
      Sultana DA, Tomita S, Hamada M, Itisanaga Y, Kitahama Y, Nguyen VK, Hirai S, Ohigashi I, Nitta S, Amagai T, Takahashi S and Takahama Y(*These two authors equally contributed to this work.)
    • Journal Title

      Blood (in press)

    • Related Report
      2008 Final Research Report
    • Peer Reviewed
  • [Journal Article] Quercetin Glucuronide Inhibits Cell Migration and Proliferation by Platelet-Derived Growth Factor in Vascular Smooth Muscle Cells2009

    • Author(s)
      Ishizawa K, Izatva-Ishizatva Y, Ohnishi S, Motobayshi Y, Kawazoe K, Hamano S, Tsuchiya K, Tomita S, Minakuchi K, and Tamaki T
    • Journal Title

      JPharmacol Sci 109

      Pages: 257-264

    • NAID

      10025734551

    • Related Report
      2008 Final Research Report
    • Peer Reviewed
  • [Journal Article] Drug discovery for overcoming CKD : Development of drugs on endathelial cell Protection for overcoming CKD2009

    • Author(s)
      Ishizawa K, Yamaguchi K, Horinouchi Y, Fukuhara Y, Tajima S, Hamano S, Tomita S, Tsuchiya K, and Tamaki T
    • Journal Title

      JPharmaco1 Sc 109

      Pages: 14-19

    • Related Report
      2008 Final Research Report
    • Peer Reviewed
  • [Journal Article] 低酸素応答転写因子の組織リモデリングへの関与2009

    • Author(s)
      冨田修平, 玉置俊晃
    • Journal Title

      日薬理誌

      Pages: 133-298

    • NAID

      10025740819

    • Related Report
      2008 Final Research Report
  • [Journal Article] Adiponectin inhibits insulin-like growth factor-1-induced cell migration via the suppression of extracellular signal-regulated kinase 1/2 activation, but not Akt in vascular smooth muscle cells.2009

    • Author(s)
      Motobayashi Y, et al.
    • Journal Title

      Hypertens Res 32

      Pages: 188-193

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Quercetin Glucuronide Inhibits Cell Migration and Proliferation by Platelet-Derived Growth Factor in Vascular Smooth Muscle Cells.2009

    • Author(s)
      Ishizawa K, et al.
    • Journal Title

      J Pharmacol Sci 109

      Pages: 257-264

    • NAID

      10025734551

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Gene expression profile of third pharyngeal pouch reveals role of mesenchymal MafB in embryonic thymus development.2009

    • Author(s)
      Tomita S, et al.
    • Journal Title

      Blood 113(印刷中)

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Drug discovery for overcoming CKD : Development of drugs on endothelial cell protection for overcoming CKD.2009

    • Author(s)
      Ishizawa K, et al.
    • Journal Title

      J Pharmacol Sci 109

      Pages: 14-19

    • Related Report
      2008 Annual Research Report
  • [Journal Article] 低酸素応答転写因子の組織リモデリングヘの関与2009

    • Author(s)
      冨田修平, 他
    • Journal Title

      日薬理誌 133

      Pages: 298-298

    • Related Report
      2008 Annual Research Report
  • [Journal Article] Law-dose dioxins alter gene expression related to cholesterol biosynthesis, lipogenesis, and glucose metabolism through the arylhydrocarbon receptor-mediated pathway inmouse liver2008

    • Author(s)
      Sato, S., Shirakawa, H., Tomita, S., Ohsaki, Y., Haketa, K., Tooi, 0., Santo, N., Tohkin, M., Furukawa, Y., Frank J. Gonzalez and Kamai, M
    • Journal Title

      Toaicol Appl Pharmacol 229

      Pages: 10-19

    • Related Report
      2008 Final Research Report
    • Peer Reviewed
  • [Journal Article] The expression of osteopantin is increased in vessels with blood-brain barrier impairment2008

    • Author(s)
      Isvanaga Y, Ueno M, Ueki M, Huang CL, Tomita S, Okamoto Y, Ogawa T, Ueda N, Maekatiwa N and Sakamato H
    • Journal Title

      Neuropathol Appl Neurobiol 34

      Pages: 145-154

    • Related Report
      2008 Final Research Report
    • Peer Reviewed
  • [Journal Article] Tocotrienol inhibits angiogenic factors secretion from human colorectal adenocarcinoma cells via suppressing hypaxia inducible factor-1α2008

    • Author(s)
      Shibata A, Nakagawa K, Sookwong P, Tsuduki T, Tomita S, Shirakawa H, Kornai M, and Miyazawa T
    • Journal Title

      J Nutr 138

      Pages: 2136-2142

    • Related Report
      2008 Final Research Report
    • Peer Reviewed
  • [Journal Article] Dietary doses of nitrite restore the circulating nitricoxide level and improve renal injury in L-NAME-induced hypertensive rats2008

    • Author(s)
      Kanematsu Y, Yamaguchi K, Ohnishi H, Motohayashi Y, Ishizawa K, Izawa Y, Katvazoe K, Kondo S, Kagami S, Tomita S, Tsuchiya K and Tamaki T
    • Journal Title

      AmJ Physiol Renal Physiol 295

    • Related Report
      2008 Final Research Report
    • Peer Reviewed
  • [Journal Article] Effect of iron-quercetin complex on reduction of nitrite in vitro and in vivo system2008

    • Author(s)
      Ohnishi H, Iwanaga S, Kawazoe K, Ishizawa K, Orino S, Tomita S, Tsuchiya K, Kanematsu Y, Harada N, Mori K, Ishikawa Y and Tamaki T
    • Journal Title

      J Agric Food Chem 56

      Pages: 10092-10108

    • Related Report
      2008 Final Research Report
    • Peer Reviewed
  • [Journal Article] PDGFによるメサンギウム細胞遊走に対するオルメサルタンの抑制効果とその分子機構2008

    • Author(s)
      石澤啓介, 三木恵里加, 石澤有紀, 大西秀樹, Narantungalag Darjsuren, 元林有紀, 山口邦久, 土屋浩一郎, 冨田修平, 玉置俊晃
    • Journal Title

      血管 31

      Pages: 59-64

    • NAID

      10021261870

    • Related Report
      2008 Final Research Report
    • Peer Reviewed
  • [Journal Article] Tocotrienol inhibits angiogenic factors secretion from human colorectal adenocarcinoma cells via suppressing hypoxia inducible factor-1α.2008

    • Author(s)
      Shibata A, et al.
    • Journal Title

      J Nutr 138

      Pages: 2136-2142

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Dietary doses of nitrite restore the circulating nitric oxide level and improve renal injury in L-NAME-induced hypertensive rats.2008

    • Author(s)
      Kanematsu Y, et al.
    • Journal Title

      Am J Physiol Renal Physiol 295

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Effect of iron-quercetin complex on reduction of nitrite in vitro and in vivo system.2008

    • Author(s)
      Ohnishi H, et al.
    • Journal Title

      J Agr Food Chem 56

      Pages: 10092-10108

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Journal Article] PDGFによるメサンギウム細胞遊走に対するオルメサルタンの抑制効果とその分子機構2008

    • Author(s)
      石澤啓介, 他
    • Journal Title

      血管 31

      Pages: 59-64

    • NAID

      10021261870

    • Related Report
      2008 Annual Research Report
  • [Journal Article] ハイドロエチジウム蛍光分析法による細胞内スーパーオキシド検出法の評価2008

    • Author(s)
      大西秀樹, 他
    • Journal Title

      腎とフリーラジカル 9

      Pages: 37-41

    • Related Report
      2008 Annual Research Report
  • [Journal Article] オルメサルタンはPDGFによるメサンギウム細胞遊走を抑制する2008

    • Author(s)
      石澤啓介, 他
    • Journal Title

      腎とフリーラジカル 9

      Pages: 172-175

    • Related Report
      2008 Annual Research Report
  • [Journal Article] The expression of osteopontin is increased in vessels with blood-brain barrier impairment.2008

    • Author(s)
      Iwanaga Y.
    • Journal Title

      Neuropathol Appl Neurobiol (In press)

    • Related Report
      2007 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Low-dose dioxins alter gene expression related to cholesterol biosynthesis,lipogenesis,and glucose metabolism through the arylhydrocarbon receptor-mediated pathway in mouse liver.2008

    • Author(s)
      Sato, S.
    • Journal Title

      Toxicol Appl Pharm (In press)

    • Related Report
      2007 Annual Research Report
    • Peer Reviewed
  • [Journal Article] p53-induced inhibition of Hif-1 causes cardiac dysfunction during pressure overload2007

    • Author(s)
      Sano M, Minamino T, Toko H, Miyauchi H, Orima M, Qin Y, AkazaNa H, Tateno K, Kayama Y, Harada M, Shimizu I, Asahara T, Hamada H, Tomita S, Molkentin JD, Zou Y and Komuro I
    • Journal Title

      Nature 446

      Pages: 444-448

    • Related Report
      2008 Final Research Report
    • Peer Reviewed
  • [Journal Article] Big Mitogen-Activated Protein Kinasel(BMKI/extracellular signal regulated kinas 5(ERK5)is involved in platelet-derived growth factor(PDGF)-induced vascular smooth muscle cell migration2007

    • Author(s)
      Izawa Y, Yoshizumi M, Ishizawa K, Fujita Y, Kondo S, Kagami S, Kawazoe K, Tsuchiya K, Tomita S and Tamaki T
    • Journal Title

      Hypertens Res 30

      Pages: 1107-1117

    • Related Report
      2008 Final Research Report
    • Peer Reviewed
  • [Journal Article] p53-induced inhibition of Hif-1 causes cardiac dysfunction during pressure overload.2007

    • Author(s)
      Sano M.
    • Journal Title

      Nature 446

      Pages: 444-448

    • Related Report
      2007 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Big Mitogen-Activated Protein Kinase1(BMK1)/extracellular signal regulated kinase 5(ERK5)is involved in platelet-derived growth factor(PDGF)-induced vascular smooth muscle cell migration.2007

    • Author(s)
      Izawa Y.
    • Journal Title

      Hypertens Res 30

      Pages: 1107-1117

    • Related Report
      2007 Annual Research Report
    • Peer Reviewed
  • [Presentation] Hypoxia -inducible factor -1の機能不全は腎虚血再潅流障害の回復を妨げる2009

    • Author(s)
      冨田修平, 他
    • Organizer
      第82回日本薬理学会年会
    • Place of Presentation
      横浜
    • Year and Date
      2009-03-16
    • Related Report
      2008 Annual Research Report
  • [Presentation] 肺高血圧症モデルマウスにおける血管内皮細胞の低酸素応答転写因子(HIF1-β)の役割2009

    • Author(s)
      浦田将久、福原弥生、冨田修平、黒部裕嗣、吉田誉、石澤啓介、北川哲也、玉置俊晃
    • Organizer
      第38回日本心脈管作動物質学会
    • Place of Presentation
      岡山
    • Related Report
      2008 Annual Research Report 2008 Final Research Report
  • [Presentation] 動脈硬化病態進展におけるT細胞の低酸素応答性因子の役割2009

    • Author(s)
      冨田修平、黒部裕嗣、玉置俊晃
    • Organizer
      第5回宮崎サイエンスキャンプ
    • Place of Presentation
      宮崎
    • Related Report
      2008 Annual Research Report 2008 Final Research Report
  • [Presentation] Hypoxia-inducible factor-1の機能不全は腎虚血再灌流障害の回復を妨げる2009

    • Author(s)
      冨田修平、山口邦久、石澤啓介、今村優子、福原弥生、土屋浩一郎、玉置俊晃
    • Organizer
      第82回日本薬理学会年会
    • Place of Presentation
      横浜
    • Related Report
      2008 Final Research Report
  • [Presentation] L-NAME慢性投与ラツトにおける臓器障害に及ぼすnifedipine代謝物の影響2008

    • Author(s)
      石澤啓介, 他
    • Organizer
      第18回日本循環薬理学会
    • Place of Presentation
      千葉
    • Year and Date
      2008-11-21
    • Related Report
      2008 Annual Research Report
  • [Presentation] Hypoxia-lnducible Factor-1α Ameliorates lschemic Acute Renal Failure and Has a Relation with a Recovery from Acute Tubular Necrosis.2008

    • Author(s)
      Yamaguchi K, et al.
    • Organizer
      Annual meeting for American Society of Nephrology
    • Place of Presentation
      Philadelphia
    • Year and Date
      2008-11-04
    • Related Report
      2008 Annual Research Report
  • [Presentation] 腎虚血再潅流障害における低酸素応答性転写因子の分子解析の試み2008

    • Author(s)
      冨田修平
    • Organizer
      第16回大阪市大フォーラム
    • Place of Presentation
      大阪
    • Year and Date
      2008-08-01
    • Related Report
      2008 Annual Research Report
  • [Presentation] 乳児期早期心臓・大血管手術時の胸腺摘除による術後免疫細胞発生の検討2008

    • Author(s)
      黒部 裕嗣
    • Organizer
      日本胸腺研究会
    • Place of Presentation
      さいたま
    • Year and Date
      2008-02-16
    • Related Report
      2007 Annual Research Report
  • [Presentation] Hypoxia-inducible factor-1a is a tumor suppressor in early stages in a mouse model of multi-step islet carcinogenesis.2008

    • Author(s)
      Inoue, M.
    • Organizer
      Keystone Symposia(Molecular, Cellular, Physiological, and Pathogenic Responses to Hypoxia)
    • Place of Presentation
      Vancouver
    • Year and Date
      2008-01-16
    • Related Report
      2007 Annual Research Report
  • [Presentation] ヒト血管内皮細胞における細胞接着分子発現に対するnifedipine代謝物の影響2008

    • Author(s)
      福原弥生、石澤啓介、堀ノ内裕也、山口邦久、冨田修平、土屋浩一郎、玉置俊晃
    • Organizer
      第51回日本腎臓学会学術総会
    • Place of Presentation
      福岡
    • Related Report
      2008 Annual Research Report 2008 Final Research Report
  • [Presentation] 児期早期心臓・大血管手術時の胸腺摘除による術後免疫細胞発生の検討2008

    • Author(s)
      黒部裕嗣、富永崇司、来島敦史、北市隆、早渕康信、長嶋光樹、冨田修平、江川善康、高浜洋介、北川哲也
    • Organizer
      第27回日本胸腺研究会
    • Place of Presentation
      さいたま
    • Related Report
      2008 Final Research Report
  • [Presentation] 食餌性亜硝酸による生体内NO生成における鉄イオンの役割2008

    • Author(s)
      土屋浩一郎、大西秀樹、岩永智史、堀之内裕也、田島壮一郎、三口弘介、石澤啓介、山口邦久、浜野修一、冨田修平、玉置俊晃
    • Organizer
      第113回日本薬理学会近畿支部会
    • Place of Presentation
      岡山
    • Related Report
      2008 Annual Research Report 2008 Final Research Report
  • [Presentation] 高血圧ラットモデルにおけるnifedipine代謝物による臓器保護作用の検討2008

    • Author(s)
      恒石鉄平、石澤啓介、福原弥生、Narantungalag Dorjsuren、大野呂知浩、山口邦久、冨田修平、土屋浩一郎、玉置俊晃
    • Organizer
      第113回日本薬理学会近畿支部会
    • Place of Presentation
      岡山
    • Related Report
      2008 Annual Research Report 2008 Final Research Report
  • [Presentation] 肺高血圧症モデルマウスにおける血管内皮細胞の低酸素応答転写因子(HIF1-β)の役割2008

    • Author(s)
      浦田将久、冨田修平、黒部裕嗣、吉田誉、石澤啓介、Frank Gonzalez、北川哲也、玉置俊晃
    • Organizer
      第29回日本炎症再生医学会年会
    • Place of Presentation
      東京
    • Related Report
      2008 Annual Research Report 2008 Final Research Report
  • [Presentation] 腎虚血再灌流障害における低酸素応答性転写因子の分子解析の試み2008

    • Author(s)
      冨田修平
    • Organizer
      第16回大阪市大フォーラム
    • Place of Presentation
      大阪
    • Related Report
      2008 Final Research Report
  • [Presentation] 動脈硬化の病態進展におけるT細胞のHIF-laの役割2008

    • Author(s)
      .冨田修平、黒部裕嗣、浦団将久、福原弥生、石澤有紀、神原保、石澤啓介、上屋浩一郎、北川哲也、玉置俊晃
    • Organizer
      第114回日本薬理学会近畿部会
    • Place of Presentation
      神戸
    • Related Report
      2008 Annual Research Report 2008 Final Research Report
  • [Presentation] 蛍光色素PhenGreenSKを用いた細胞内遊離2価鉄測定法2008

    • Author(s)
      濱本磨以、久住祥子、富澤彩智、田島壮一郎、石澤啓介、冨田修平、山口邦久、庄野正行、吉村好之、滝口祥令、土屋浩一郎、玉置俊晃
    • Organizer
      第20回腎とフリーラジカル研究会
    • Place of Presentation
      大阪
    • Related Report
      2008 Annual Research Report 2008 Final Research Report
  • [Presentation] L-MME慢性投与ラットにおける臓器障害に及ぼすnifedipine代謝物の影響2008

    • Author(s)
      石澤啓介、福原弥生、堀ノ内裕也、恒石鉄平、山口邦久、冨田修平、土屋浩一郎、玉置俊晃
    • Organizer
      第18回日本循環薬理学会
    • Place of Presentation
      千葉
    • Related Report
      2008 Final Research Report
  • [Presentation] 低容量ダイオキシンによる脂質代謝に関する遺伝子の発現変化2008

    • Author(s)
      佐藤祥子、白川仁、冨田修平、駒井三千夫
    • Organizer
      第31回日本分子生物学会第81回日本生化学会合同大会
    • Place of Presentation
      神戸
    • Related Report
      2008 Annual Research Report 2008 Final Research Report
  • [Presentation] Hypoxia-inducible factor-la is a tumor suppressor in early stages in a mouse model of multi-step islet carinogenesis. Keystone Symposia(Molecular, Cellular, Physiological, and Pathogenic Responses to Hypoxia2008

    • Author(s)
      Inoue, M., Takeda, T., Endo, H., Tomita, S.
    • Organizer
      Vancouver
    • Place of Presentation
      British Columbia
    • Related Report
      2008 Final Research Report
  • [Presentation] Hypoxia-Inducible Factor-1 α Ameliorates Ischemic Acute Renal Failure and Has a Relation with a Recovery from Acute Tubular Necrosis2008

    • Author(s)
      Yamaguchi K, Ishizawa K, Tomita S, Tsuchiya K, Konda S, Kagansi S, Tamaki T
    • Organizer
      Annual meeting for American Society of Nephrology, Philadelphia
    • Place of Presentation
      Pennsylvania
    • Related Report
      2008 Final Research Report
  • [Presentation] ヒトメタロチオネイン2A遺伝子の転写制御に関するAhレセプターとグルココルチコイドレセプターの相互作用2007

    • Author(s)
      佐藤 祥子
    • Organizer
      日本分子生物学会・日本生化学会合同大会
    • Place of Presentation
      横浜
    • Year and Date
      2007-12-12
    • Related Report
      2007 Annual Research Report
  • [Presentation] The role of HIF-1 in fetal thymus development2007

    • Author(s)
      HIRAI Shuichi
    • Organizer
      日本免疫学会総会
    • Place of Presentation
      品川
    • Year and Date
      2007-11-22
    • Related Report
      2007 Annual Research Report
  • [Presentation] Role of MafB in the development of the thymus2007

    • Author(s)
      TOMITA Shuhei
    • Organizer
      日本免疫学会総会
    • Place of Presentation
      品川
    • Year and Date
      2007-11-20
    • Related Report
      2007 Annual Research Report
  • [Presentation] Hif-1a in T cells plays a crucial role in the progression of arteriosclerosis and artery intimal thickening.2007

    • Author(s)
      Kurobe, H.
    • Organizer
      AHA Scientific Sessions
    • Place of Presentation
      Orlando
    • Year and Date
      2007-11-07
    • Related Report
      2007 Annual Research Report
  • [Presentation] 胸腺初期発生における低酸素応答の役割2007

    • Author(s)
      平井 宗一
    • Organizer
      四国免疫フォーラム
    • Place of Presentation
      愛媛
    • Year and Date
      2007-07-14
    • Related Report
      2007 Annual Research Report
  • [Presentation] 第三咽頭嚢発現遺伝子の探索から明らかになったMafBの胸腺発生への関与2007

    • Author(s)
      冨田 修平
    • Organizer
      Kyoto T Cell Conference
    • Place of Presentation
      京都
    • Year and Date
      2007-06-15
    • Related Report
      2007 Annual Research Report
  • [Presentation] 新生児期胸腺摘除が免疫形成に与える影響2007

    • Author(s)
      黒部裕嗣、富永崇司、来島敦史、早渕康信、長嶋光樹、冨田修平、江川善康、北川哲也、高浜洋介
    • Organizer
      第26回日本胸腺研究会
    • Place of Presentation
      徳島
    • Related Report
      2008 Final Research Report
  • [Presentation] 胸腺初期発生における低酸素応答の役割2007

    • Author(s)
      平井宗一、冨田修平、Nguyen Van Khang、高浜洋介
    • Organizer
      第6回四国免疫フォーラム
    • Place of Presentation
      愛媛
    • Related Report
      2008 Final Research Report
  • [Presentation] 第三咽頭嚢発現遺伝子の探索から明らかになったMafBの胸線発生への関与2007

    • Author(s)
      冨田修平、Dil Afroz Sultana、平井宗一、Nguyen Van Khan、濱田理人、高橋智、高浜洋介
    • Organizer
      Kyoto T Cell Conference
    • Place of Presentation
      京都
    • Related Report
      2008 Final Research Report
  • [Presentation] Role of MafB in the development of the thymus2007

    • Author(s)
      TOMITA Shuhei, SULTANA DilAfroz, HIRAI Shuichi, KHANG Nguyen Van, TAKAHASHI Sataru, , TAKAHAMA Yousuke
    • Organizer
      第37回目本免疫学会総会
    • Place of Presentation
      品川
    • Related Report
      2008 Final Research Report
  • [Presentation] The role of HIF-1 in fetal thymus developmont2007

    • Author(s)
      HIRAI Shuichi, TOMITA Shuhei, NGUYEN Van Khang, TAKAHAMA Yousuke
    • Organizer
      第37回日本免疫学会総会
    • Place of Presentation
      品川
    • Related Report
      2008 Final Research Report
  • [Presentation] ヒトメタロチオネイン2A遺伝子の転写制御に関するAhレセプターとグルココルチコイドレセプターの相互作用2007

    • Author(s)
      佐藤洋子、白川仁、冨田修平、駒井三千夫
    • Organizer
      第30回日本分子生物学会第80回日本生化学会合同大会
    • Place of Presentation
      横浜
    • Related Report
      2008 Final Research Report
  • [Presentation] Hif-la in T cells plays a crucial role in the progression of arteriosclerosis and artery intimal thickening2007

    • Author(s)
      Kuorabe, H., Urata, M., Izawa, Y., Fukuhara, Y., Kanbara, T., Aihara, K.I., Akaike, M., Gonzalez, F., Matsumoto, T., Tamaki, T., Kitagawa, T., Yoshizumi, M., Tomita, S
    • Organizer
      AHA Scientific Sessions
    • Place of Presentation
      Orlando, Florida
    • Related Report
      2008 Final Research Report
  • [Book] ハイドロエチジウム蛍光分析法による細胞内スーパーオキシド検出法の評価2008

    • Author(s)
      大西秀樹, 土屋浩一郎, 田島壮一郎, 堀ノ内裕也, 山口邦久, 石澤啓介, 冨田修平, 玉置俊晃
    • Publisher
      腎とフリーラジカル(9)
    • Related Report
      2008 Final Research Report
  • [Book] オルメサルタンはPDGFによるメサンギウム細胞遊走を抑制する2008

    • Author(s)
      石澤啓介, 三木恵里加, 石澤有紀, 大西秀樹, Narantungalag Dorjsuren, 元林有紀, 山口邦久, 土屋浩一郎, 冨田修平, 玉置俊晃
    • Publisher
      腎とフリーラジカル(9)
    • Related Report
      2008 Final Research Report
  • [Book] 医学のあゆみ, Vascular Biology Update『中枢神経系と血管形成』2008

    • Author(s)
      冨田 修平
    • Publisher
      医歯薬出版
    • Related Report
      2007 Annual Research Report
  • [Book] 中枢神経系と血管形成(Vascular Biology Update)2007

    • Author(s)
      冨田修平
    • Publisher
      医学のあゆみ(223)
    • Related Report
      2008 Final Research Report

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Published: 2007-04-01   Modified: 2016-04-21  

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