• Search Research Projects
  • Search Researchers
  • How to Use
  1. Back to previous page

Analyses of epigenetic mechanism of lymphomagenesis/leukemogenesis

Research Project

Project/Area Number 19590349
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeSingle-year Grants
Section一般
Research Field Human pathology
Research InstitutionOkayama University

Principal Investigator

OKA Takashi  Okayama University, 大学院・医歯薬学総合研究科, 助教 (50160651)

Co-Investigator(Kenkyū-buntansha) YOSHINO Tadashi  岡山大学, 大学院・医歯薬学総合研究科, 教授 (70183704)
OUCHIDA Mamoru  岡山大学, 大学院・医歯薬学総合研究科, 准教授 (80213635)
Project Period (FY) 2007 – 2008
Project Status Completed (Fiscal Year 2008)
Budget Amount *help
¥4,420,000 (Direct Cost: ¥3,400,000、Indirect Cost: ¥1,020,000)
Fiscal Year 2008: ¥2,080,000 (Direct Cost: ¥1,600,000、Indirect Cost: ¥480,000)
Fiscal Year 2007: ¥2,340,000 (Direct Cost: ¥1,800,000、Indirect Cost: ¥540,000)
Keywordsエピジェネテイックス / 悪性リンパ腫 / 白血病 / ATLL / MALTリンパ腫 / HTLV-I / H.pylori / DNAメチル化 / MALT lymphoma
Research Abstract

悪性腫瘍の発症機構に関する研究は、これまで癌遺伝子、癌抑制遺伝子の構造異常などを伴うゼネテイックな変化に注目して研究が進められてきた。それに対し近年遺伝子の構造異常を伴わないエピジェネテイックな機構による発癌が注目されてきている。我々は造血器腫瘍の発症機構をとくにエピジェネテイックな機構に注目し解析を行い、HTLV-I, H.pyloriの感染によって異常なDNAメチル化が誘導・蓄積することが造血器腫瘍発症に重要であることを見いだした。これらの知見を元に造血器腫瘍を高感度に早期発見・早期診断することが可能になると期待される。

Report

(3 results)
  • 2008 Annual Research Report   Final Research Report ( PDF )
  • 2007 Annual Research Report
  • Research Products

    (44 results)

All 2008 2007 Other

All Journal Article (14 results) (of which Peer Reviewed: 12 results) Presentation (29 results) Patent(Industrial Property Rights) (1 results)

  • [Journal Article] Duodenal follicular lymphomas share common characteristics with mucosa-associated lymphoid tissue lymphomas2008

    • Author(s)
      Sato Y, Ichimura K, Tanaka T, Takata K, Morito T, Sato H, Kondo E, Yanai H, Ohara N, Oka T, Yoshino T
    • Journal Title

      J Clin Pathol 61(3)

      Pages: 377-81

    • Related Report
      2008 Final Research Report
    • Peer Reviewed
  • [Journal Article] リンパ系腫瘍におけるDNAメチル化異常2008

    • Author(s)
      岡剛史、吉野正
    • Journal Title

      血液フロンテイア 18(11)

      Pages: 1-9

    • Related Report
      2008 Final Research Report
  • [Journal Article] Duodenal follicular lymphomas share common characteristics with mucosa-associated lymphoid tissue lymphomas.2008

    • Author(s)
      Sato Y, Oka T, Yoshino T., et al
    • Journal Title

      J Clin Pathol. 61

      Pages: 377-381

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Journal Article] リンパ系腫瘍におけるDNAメチル化異常2008

    • Author(s)
      岡 剛史, 吉野正
    • Journal Title

      血液フロンティア 18

      Pages: 1-9

    • Related Report
      2008 Annual Research Report
  • [Journal Article] Down-regulation of drs Mrna is associated with the progression of adult T-cell leukemia/lymphoma2007

    • Author(s)
      Shimakage, M., Inoue, N., Oshima,K., Kawahara, K., Yamamoto, N., Oka, T., Tambe, Y.,Yasui, K., Matsumoto, K., Yutsudo, M., and Inoue, H
    • Journal Title

      Int. J. Oncol 30(6)

      Pages: 1343-8

    • Related Report
      2008 Final Research Report
    • Peer Reviewed
  • [Journal Article] Immunoelectron-microscopic study of CD4- and CD8-positive lymphocytes from healthy donors seropositive for human T-lymphotropic virus type I2007

    • Author(s)
      Ohtsuki Y., Oka T., Manabe Y., Takeuchi T., Lee G, H., Furihata M., Yoshino T., Taguchi H. and Miyoshi I
    • Journal Title

      Biomedical Res 18(2)

      Pages: 83-88

    • Related Report
      2008 Final Research Report
    • Peer Reviewed
  • [Journal Article] Duodenal follicular lymphomas share common characteristics with mucosa-associated lymphoid tissue lymphomas2007

    • Author(s)
      Sato Y, Ichimura K, Tanaka T, Takata K, Morito T, Sato H, Sato Y, Kondo E, Yanai H, Ohara N, Oka T, Yoshino T
    • Journal Title

      J Clin Pathol 61

      Pages: 377-381

    • Related Report
      2008 Final Research Report
    • Peer Reviewed
  • [Journal Article] High frequent gene silencing of hematopoietic cell specific protein tyrosine phosphatase SHP1 in hematopoietic cell malignancies2007

    • Author(s)
      T. Oka., M. Ouchida., M. Tanimoto., K. Shimizu and T. Yoshino.
    • Journal Title

      Int. J. Med. Biol. Fronteiers 11

      Pages: 11-42

    • Related Report
      2008 Final Research Report
    • Peer Reviewed
  • [Journal Article] High frequent gene silencing of hematopoietic cell specific protein tyrosine phosphatase SHP1 in hematopoietic cell malignancies.2007

    • Author(s)
      T. Oka., M. Ouchida., M. Tanimoto., K. Shimizu and T. Yoshino.
    • Journal Title

      Int. J. Med. Biol. Front。 11

      Pages: 11-42

    • Related Report
      2007 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Duodenal follicular lymphomas share common characteristics with mucosa-associated lymphoid tissue lymphomas.2007

    • Author(s)
      Sato Y, Ichimura K, Ohara N, Oka T, Yoshino T., et. al.
    • Journal Title

      J Clin Pathol. 61

      Pages: 377-381

    • Related Report
      2007 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Immunoelectron-microscopic study of CD4-and CD8-positive lymphocytes from healthy donors seropositive for human T-lymphotropic virus type I.,2007

    • Author(s)
      Ohtsuki Y., Oka T., Manabe Y., Takeuchi T., Lee G, H., et. al.
    • Journal Title

      Biomedical Res. 18

      Pages: 83-88

    • Related Report
      2007 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Down-regulation of drs mRNA is associated with the progression of adult T-cell leukemia/lymphoma.2007

    • Author(s)
      Shimakage, M., Inoue, N., Oshima, K., Kawahara, K., Yamamoto, N., Oka, T., Tambe, Y., Yasui, K., Matsumoto, K., Yutsudo, M., and Inoue. H.
    • Journal Title

      Int. J. Oncol., 30

      Pages: 1343-11348

    • Related Report
      2007 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Accumulation of aberrant CpG hypermethylation by Helicobacter pylori infection promotes development and progression of gastric MALT lymphoma

    • Author(s)
      Takami Kondo, Takashi Oka, Hiaki Sato, Yoko Shinnou, Kana Washio, Masayuki Takano, Toshiaki Morito, Katsuyoshi Takata, Nobuya Ohara, Mamoru Ouchida, Kenji Shimizu, and Tadashi Yoshino
    • Journal Title

      Int. J. Oncol (In press)

    • Related Report
      2008 Final Research Report
    • Peer Reviewed
  • [Journal Article] Duodenal and nodal follicular lymphomas are distinct : the former lacks activation-induced cytidine deaminase an folliculardendritc cells despite ngoing smatic hypermutaion

    • Author(s)
      Takata K, Sato Y, Nakamura N, Kikuchi Y.Y, Ichimura K, Tanaka T, Morito T, Tamura M, Oka T, Kondo E, Okada H, Tari A and Yoshino T
    • Journal Title

      Mod. Pathol (In press)

    • Related Report
      2008 Final Research Report
    • Peer Reviewed
  • [Presentation] 悪性腫瘍とエピジェネティックス; 造血器腫瘍発症・進展におけるエピジェネティック異常2008

    • Author(s)
      岡剛史
    • Organizer
      第40回日本臨床分子形態学会
    • Place of Presentation
      福岡
    • Year and Date
      2008-10-04
    • Related Report
      2008 Final Research Report
  • [Presentation] 悪性腫瘍とエピジェネテイツクス ; 造血器腫瘍発症・進展におけるエピジェネテイ2008

    • Author(s)
      岡 剛史
    • Organizer
      第40回日本臨床分子形態学会
    • Place of Presentation
      福岡
    • Year and Date
      2008-10-04
    • Related Report
      2008 Annual Research Report
  • [Presentation] 成人T細胞白血病/リンパ腫(ATLL)における特異的DNAメチル化と病態・予後との相関2008

    • Author(s)
      佐藤妃映、岡 剛史、神農陽子、鷲尾佳奈、高野正幸、高田尚良、守都敏晃、田村麻衣子、黄 新剛、大西尚子、大内田守、大島孝一、宇都宮與、高橋聖之、谷本光音、吉野正
    • Organizer
      第1回HTLV1研究会
    • Place of Presentation
      東京
    • Year and Date
      2008-08-20
    • Related Report
      2008 Final Research Report
  • [Presentation] Identification of the specific genes regulated by epigenetic mechanism during osteoblastic/adipocytic differentiations in human mesenchymal stem cells2008

    • Author(s)
      Masayuki Takano, Takashi Oka, Yoko Shinnou, Takami Kondo, Hiaki Sato, Kana Washio, Toshiaki Morito, Katsuyoshi Takata, Ichiro Murakami, Nobuya Ohara, Tohru Nakanishi , Tadashi Yoshino
    • Organizer
      第31回日本分子生物学会、第81回日本精化学会合同大会
    • Place of Presentation
      神戸
    • Related Report
      2008 Final Research Report
  • [Presentation] Effect of nitrogen containing bisphosphonate on osteoblast differentiation of rat mesenchymal stem cell2008

    • Author(s)
      Kaduko Kurokawa, Hirofumi Fujita, Eri Oyanagi, Takashi Oka, Kozo Utsumi and Junzo Sasaki
    • Organizer
      第31回日本分子生物学会、第81回日本精化学会合同大会
    • Place of Presentation
      神戸
    • Related Report
      2008 Final Research Report
  • [Presentation] 成人T細胞白血病/リンパ腫(ATLL)におけるDNAメチル化の解析2008

    • Author(s)
      佐藤妃映、岡剛史、神農陽子、鷲尾佳奈、高田尚良、守都敏晃、田村麻衣子、黄 新剛、北村雄太、大原信哉、村上一郎、清水憲二、大内田守、谷本光音、大島孝一、宇都宮與、高橋聖之、吉野正
    • Organizer
      第31回日本分子生物学会、第81回日本精化学会合同大会
    • Place of Presentation
      神戸
    • Related Report
      2008 Final Research Report
  • [Presentation] Immunohistochemical analyses of PTPN6(SHP1) on Langerhnas cell histiocytosis2008

    • Author(s)
      Ichiro Murakami, Takashi Oka, Hiaki Sato, Toshiaki Morito, Katsuyoshi Takata, Yoko Shinno, Nobuya Ohara, Eisaku Kondo, Kiyoshi Takahasi, akehiro Tanaka, Tdashi Yoshino
    • Organizer
      67^<th> Annual meetin of the Japanese Cancer association
    • Place of Presentation
      Nagoya
    • Related Report
      2008 Final Research Report
  • [Presentation] Molecular Pathological examination on aberrant expression of cyclinD1 and CD79a in multiple myeloma cell lines2008

    • Author(s)
      Takata K., Oka T., Tanaka T., Sato H., Murakami I., Morito T., Takano M., Washio K., Otsuki T., and YoshinoT
    • Organizer
      67^<th> Annual meeting of the Japanese Cancer association
    • Place of Presentation
      Nagoya
    • Related Report
      2008 Final Research Report
  • [Presentation] IMMUNOHISTOCHEMICAL ANALYSES OF PTPN6 (SHP1) ON LANGERHANS CELL HISTIOCYTOSIS2008

    • Author(s)
      Ichiro Murakami, Takashi Oka, Hiaki Sato, Yuta Kitamura, Toshiaki Morito, Katsuyoshi Takata, Yoko Shinno, Masayuki Takano, Kana Washio, Xingang Huang, Maiko Tamura, Naoko Ohnishi, Koichi Ichimura,Yasuharu Sato, Hiroyuki Yanai, Nobuya Ohara, Eisaku Kondo, Kiyoshi Takahashi, Takehiro Tanaka, Jean Gogusev, FranciJaubert, Akira Morimoto, Shinsaku Imashuku, Tadaatsu Akagi, Tadashi Yoshino
    • Organizer
      Annual Meeting of the Histiocyte Society
    • Place of Presentation
      Germany
    • Related Report
      2008 Final Research Report
  • [Presentation] 成人T細胞白血病/リンパ腫(ATLL)における特異的DNAメチル化と病態との関連2008

    • Author(s)
      佐藤妃映、岡 剛史、神農陽子、鷲尾佳奈、高田 尚良、守都 敏晃、大原信哉、大内田守、大島孝一、谷本光音、宇都宮與、高橋聖之、吉野正
    • Organizer
      H20リンパ網内系学会
    • Place of Presentation
      札幌
    • Related Report
      2008 Final Research Report
  • [Presentation] Immunohstochemical analysis of PTPN6 (SHP-1) on Langerhans cell histiocytosis2008

    • Author(s)
      Ichiro Murakami, Takashi Oka, Tadashi Yoshino
    • Organizer
      第97回日本病理学会
    • Place of Presentation
      金沢
    • Related Report
      2008 Final Research Report
  • [Presentation] 成人T細胞白血病/リンパ腫(ATLL)における特異的DNAメチル化と予後との相関について2008

    • Author(s)
      佐藤妃映、岡剛史、神農陽子、鷲尾佳奈、高野正幸、高田尚良, 守都敏晃,大原信哉、大内田守,大島孝一、宇都宮與、高橋聖之、吉野正
    • Organizer
      第97回日本病理学会
    • Place of Presentation
      金沢
    • Related Report
      2008 Final Research Report
  • [Presentation] T cellリンパ腫におけるSHP1の発現低下と、脱メチル化処理による発現回復がSignal pathwayに及ぼす変化2008

    • Author(s)
      神農陽子、岡剛史、佐藤妃映、高野正幸、村上一郎、鷲尾佳奈、高田尚良、守都敏晃、黄新剛、田村麻衣子、大西尚子、吉野正
    • Organizer
      第97回日本病理学会
    • Place of Presentation
      金沢
    • Related Report
      2008 Final Research Report
  • [Presentation] 樹状細胞と樹状マクロファージから視た胸腺腫のWHO分類2008

    • Author(s)
      高橋聖之、富坂竜矢、西川由利子、佐藤妃映、岡剛史、吉野正
    • Organizer
      第97回日本病理学会
    • Place of Presentation
      金沢
    • Related Report
      2008 Final Research Report
  • [Presentation] Immunohistochinalanalysis of PTPN6(SHP1) on Langerhans cell histiocytosis2007

    • Author(s)
      Ichiro Murakami, Takashi Oka , Hiaki Sato, Toshiaki Morito, Katsuyoshi Takata, Yoko Shinnou, Kan Washo, Masayuki Takano, Nobuya Ohara, and Todashi Yoshino
    • Organizer
      66^<th> Annual meeting of the Japanese Cancer association
    • Place of Presentation
      Yokohma, Japan
    • Related Report
      2008 Final Research Report
  • [Presentation] Assciation of aberrant DNA methylation with linicopthoogic characteristics in Adult T cell leukemia/lymphoma (ATLL)2007

    • Author(s)
      Hiaki Sato, Takashi Oka, Yoko Shinnou, Kana Washio, Masayuki Takano, Nobuya Ohara, Mamoru Ouchia, Koichi hshima, Kenji Shimiz, Mitsne Tanimoto, Kiyoshi Takahashi, Atae Utsunomiya Tadashi Yoshino
    • Organizer
      66^<th> Annual meeting of the Japanese Cancer association
    • Place of Presentation
      Yokohma, Japan
    • Related Report
      2008 Final Research Report
  • [Presentation] Genes specifically changing DNA methylation during osteoblastic/adipocytic differentiations in mesenchymal stem cells2007

    • Author(s)
      Masayuki Takano, Takashi Oka, Yoko Shinnou, Takami Kondo Hiaki Sato, Kana Washio, Ichiro Murakai, Nobuya Ohara, adashYoshino
    • Organizer
      66th Annual meeting of the JapCancer association
    • Place of Presentation
      Yokohma, Japan
    • Related Report
      2008 Final Research Report
  • [Presentation] Molecular Pathological examination on aberrant expression of cyclinD1 and CD79a in multiple myeloma cell lines2007

    • Author(s)
      Takata K., Oka T., Tanaka T., Sato H., Murakami I., Morito T., Takano M., Washio K., Otsuki T., and Yoshino T
    • Organizer
      6th Annual meetin of the Japanese Cancer association
    • Place of Presentation
      Yokohma, Japan
    • Related Report
      2008 Final Research Report
  • [Presentation] 成人T細胞白血病/リンパ腫(ATLL)における特異的DNAメチル化と病態・臨床症状との相関2007

    • Author(s)
      佐藤妃映、岡剛史、近藤孝美、高野正幸、神農陽子、鷲尾佳奈、高田尚良、守都敏晃、大原信哉,大内田守、大島孝一、谷本光音、宇都宮與、高橋聖之、吉野正
    • Organizer
      第47回日本リンパ網内系学会総会
    • Place of Presentation
      淡路
    • Related Report
      2008 Final Research Report 2007 Annual Research Report
  • [Presentation] 胃原発悪性リンパ腫の発症・進展と特異的遺伝子のepigeneticな変化に関する検討2007

    • Author(s)
      近藤孝美、岡剛史、神農陽子、佐藤妃映、鷲尾佳奈、高野正幸、高田尚良、守都敏晃、大原信哉、大内田守、吉野正
    • Organizer
      第47回日本リンパ網内系学会総会
    • Place of Presentation
      淡路
    • Related Report
      2008 Final Research Report 2007 Annual Research Report
  • [Presentation] EPIGENETICALLY DISTINST MALIGNANT CELL POLULATION FORMS LYMPHOMA-INVOLVING LESION IN ACUTE TYPE ADULT T-CELL LEUKEMIA/LYMPHOMA (ATLL)2007

    • Author(s)
      Takashi Oka, Hiaki Sato, Yoko Nakatani, Takami Kondo, Kana Washio, Masayuki Takano, Ichiro Murakami, Nobuya Ohara , Mamoru Ouchida, Koichi Ohshima, Kenji Shiu, Mitsune animoto, Kiyoshi Takahhi, Atae Utsunomiya, Tadashi Yoshino
    • Organizer
      13th International Coference on Human Retrovirology HTLV and Related Viruses
    • Place of Presentation
      Hakone, Japan
    • Related Report
      2008 Final Research Report
  • [Presentation] ABERRANT DNA METHYLATIONIS ASSOCIATD WITH THE CLINICOPATHOLOGIC CHARACTERISTICS IN PATIENTS WITH ADUL T-CELL LENKEMIA/LYMPHOMA(ATLL)2007

    • Author(s)
      Hiaki Sato, Takashi Oka, Yoko Nakatani, Takami Kondo, Kana Washio, Masayuki Takano, Ichiro Murakami, Nobuya Ohara , Mamoru Ouchida, Koichi Ohshima, Kenji Shimizu, Mitsune Tanimoto, Kiyoshi Takahashi, Atae Utsunomiya, Tadashi Yoshino
    • Organizer
      13th International Coference on Human Retrovirology HTLV and Rted Viruses
    • Place of Presentation
      Hakone, Japan
    • Related Report
      2008 Final Research Report
  • [Presentation] CPG SLAND METHYLATOR PHENOTYPE (CIMP) PROMOTES THE PROGRESSION OF ADULT LEUKEMIA/LYMPHOMA(ATLL)2007

    • Author(s)
      Hiaki Sato Takashi Oka Yoko Nakatani Takami Kondo Kana Washio Masayuki Takano Nobuya Ohara Mamoru Ouchida KoicOshima Kenjhimizu Mitsune Tanimoto Khi TakahaAtae Utsunomiya Tadhi Yoshino
    • Organizer
      13th International Conference on Human Retrovirology HTVL and Related Viruses
    • Place of Presentation
      Hakone, Japan
    • Related Report
      2008 Final Research Report
  • [Presentation] EPIGENETICALLY DISTINST MALIGNANT CELL POLULATION FORMS LYMPHOMA-INVOLVING LESION IN ACUTE TYPE ADULT T-CELL LEUKEMIA/LYMPHOMA (ATLL).2007

    • Author(s)
      Takashi Oka1), Hiaki Sato1, 5), Yoko Nakatani1), Takami Kondo1), Kana Washio1), Masayuki Takano1), Ichiro Murakami7), Nobuya Ohara 1), Mamoru Ouchida2), Koichi Ohshima3), Kenji Shimizu2), Mitsune Tanimoto4), Kiyoshi Takahashi5), Atae Utsunomiya6), Tadashi Yoshino1)
    • Organizer
      13th International Conference on Human Retrovirology HTLV and Related Viruses
    • Place of Presentation
      Hakone, Japan
    • Related Report
      2007 Annual Research Report
  • [Presentation] ABERRANT DNA METHYLATION IS ASSOCIATED WITH THE CLINICOPATHOLOGIC CHARACTERISTICS IN PATIENTS WITH ADULT T-CELL LEUKEMIA/LYMPHOMA (ATLL).2007

    • Author(s)
      Hiaki Sato1, 5), Takashi Oka1), Yoko Nakatani1), Takami Kondo1), Kana Washio1), Masayuki Takano1), Ichiro Murakami7), Nobuya Ohara 1), Mamoru Ouchida2), Koichi Ohshima3), Kenji Shimizu2), Mitsune Tanimoto4), Kiyoshi Takahashi5), Atae Utsunomiya6), Tadashi Yoshino1)
    • Organizer
      13th International Conference on Human Retrovirology HTLV and Related Viruses
    • Place of Presentation
      Hakone, Japan
    • Related Report
      2007 Annual Research Report
  • [Presentation] CPG ISLAND METHYLATOR PHENOTYPE (CIMP) PROMOTES THE PROGRESSION OF ADULT T-CELL LEUKEMIA/LYMPHOMA (ATLL).2007

    • Author(s)
      Hiaki Sato1, 5) Takashi Oka1) Yoko Nakatani1) Takami Kondo1) Kana Washio1) Masayuki Takano1) Nobuya Ohara 1) Mamoru Ouchida2) Koichi Oshima3) Kenji Shimizu2) Mitsune Tanimoto4) Kiyoshi Takahashi5) Atae Utsunomiya6) Tadashi Yoshino1)
    • Organizer
      13th International Conference on Human Retrovirology HTLV and Related Viruses
    • Place of Presentation
      Hakone, Japan
    • Related Report
      2007 Annual Research Report
  • [Presentation] Immunohistochemical analyses of PTPN6 (SHP1) on Langerhans cell histiocytosis.2007

    • Author(s)
      Ichiro Murakami, Takashi Oka Hiaki Sato, Toshiaki Morito, Katsuyoshi Takata, Yoko Shinnou1), Kana Washio1), Masayuki Takano1), Nobuya Ohara1), and Tadashi Yoshino
    • Organizer
      66thAnnual meeeting of the Japanese Cancer association
    • Place of Presentation
      Yokohama, Japan
    • Related Report
      2007 Annual Research Report
  • [Presentation] Association of aberrant DNA methylation with clinicopahthologic characteristics in Adult T cell leukemia/lymphoma (ATLL).2007

    • Author(s)
      Hiaki Sato1), Takashi Oka1), Yoko Shinnou1), Kana Washio1), Masayuki Takano1), Nobuya Ohara1), Mamoru Ouchida2), Koichi Ohshima4), Kenji Shimizu2), Mitsune Tanimoto3), Kiyoshi Takahashi1), Atae Utsunomiya5), Tadashi Yoshino1)
    • Organizer
      66thAnnual meeeting of the Japanese Cancer association
    • Place of Presentation
      Yokohama, Japan
    • Related Report
      2007 Annual Research Report
  • [Presentation] Genes specifically changing DNA methylation during osteoblastic/adipocytic differentiations in mesenchymal stem cells2007

    • Author(s)
      Masayuki Takano1, Takashi Oka1, Yoko Shinnou1, Takami Kondo1, Hiaki Sato1, 2, Kana Washio1, Ichiro Murakami3, Nobuya Ohara1, Tadashi Yoshino1
    • Organizer
      66thAnnual meeeting of the Japanese Cancer association
    • Place of Presentation
      Yokohama, Japan
    • Related Report
      2007 Annual Research Report
  • [Patent(Industrial Property Rights)] 成人T細胞白血病・リンパ腫 (ATLL)の予後推定法及びキャト2008

    • Inventor(s)
      岡剛史、佐藤妃映、大内田守、吉野正、
    • Industrial Property Rights Holder
      岡山大学
    • Industrial Property Number
      2008-071783
    • Filing Date
      2008-03-19
    • Related Report
      2008 Final Research Report

URL: 

Published: 2007-04-01   Modified: 2016-04-21  

Information User Guide FAQ News Terms of Use Attribution of KAKENHI

Powered by NII kakenhi