A study of Infection prevention from a new viewpoint responsible for untreated HIV patients and their cognition
Project/Area Number |
19590618
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Research Category |
Grant-in-Aid for Scientific Research (C)
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Allocation Type | Single-year Grants |
Section | 一般 |
Research Field |
Hygiene
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Research Institution | 独立行政法人国立病院機構(大阪医療センター臨床研究部) |
Principal Investigator |
MAKIE Toshio 独立行政法人国立病院機構(大阪医療センター臨床研究部), 大阪医療センター臨床研究センター, 研究員 (80435891)
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Co-Investigator(Kenkyū-buntansha) |
NAKAMURA Tsuyoshi 長崎大学, 環境科学部, 教授 (80039586)
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Project Period (FY) |
2007 – 2009
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Project Status |
Completed (Fiscal Year 2009)
|
Budget Amount *help |
¥2,470,000 (Direct Cost: ¥1,900,000、Indirect Cost: ¥570,000)
Fiscal Year 2009: ¥650,000 (Direct Cost: ¥500,000、Indirect Cost: ¥150,000)
Fiscal Year 2008: ¥650,000 (Direct Cost: ¥500,000、Indirect Cost: ¥150,000)
Fiscal Year 2007: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
|
Keywords | HIV感染症 / 未治療 / CD4リンパ球 / 季節性ストレス / 免疫能 / CD4予測 / CD4陽性Tリンパ球 / 患者の至適環境 / 予測可能性 / 治療導入 / 抗レトロウイルス療法(ART) / 細胞性免疫能力 / 環境条件 / 至適環境 |
Research Abstract |
We examined three assignments responsible for HIV patients before medication introduction ; 1) seasonal variation in CD4+ cell counts, 2) estimating CD4+ cell counts of an individual using population historical data, and 3) a feature in Japanese patients before medication introduction. The results indicated as follows ; 1) HIV patient's CD4+ cell counts decreases in early summer and increases in autumn in Japan, 2) our new method has potential that the relative coefficient between the predicted and actual CD4-counts keeps above 0.8 even in 12 month intervals, and 3) Japanese HIV patients have a feature of either the slow first hospital visit or the fast progression.
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Report
(4 results)
Research Products
(16 results)
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[Journal Article] Problems in three Japanese drug users with Human Immunodeficienc Virus infection2008
Author(s)
Kuwahara T, Nakakura Y, Oda S, Mori M, Uehara T, Yoshino M, Sasakawa A, Yajima K, Umemoto A, Takada K, Makie T, Yoshihiko Yamamoto
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Journal Title
J Med Invest 55
Pages: 156-160
Related Report
Peer Reviewed
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