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Verification behavioral state under the anterograde amnesia caused by the involuntary intake of benzodiazepine as the date rape drug-For the prevention of the illicit use of remedy

Research Project

Project/Area Number 19590664
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeSingle-year Grants
Section一般
Research Field Legal medicine
Research InstitutionAsahikawa Medical College

Principal Investigator

SHIMIZU Keiko  Asahikawa Medical College, 医学部, 教授 (90312462)

Co-Investigator(Kenkyū-buntansha) MATSUBARA Kazuo  旭川医科大学, 医学部, 教授 (20127533)
ASARI Masaru  旭川医科大学, 医学部, 助教 (40360979)
Project Period (FY) 2007 – 2009
Project Status Completed (Fiscal Year 2009)
Budget Amount *help
¥4,290,000 (Direct Cost: ¥3,300,000、Indirect Cost: ¥990,000)
Fiscal Year 2009: ¥780,000 (Direct Cost: ¥600,000、Indirect Cost: ¥180,000)
Fiscal Year 2008: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2007: ¥2,210,000 (Direct Cost: ¥1,700,000、Indirect Cost: ¥510,000)
Keywords犯罪精神医学 / 医薬品不正利用 / デートレイプドラッグ / 医薬品不正使用 / 溶解度 / 犯罪防止 / 健忘 / 行動薬理
Research Abstract

Because the illicit use of medicine for the criminal purpose is the non-medical use, there are no available clinical data for the victim needed in the deliberation of the criminal court.
In this study, we have performed the solubility test of medical substances to beverage used in the putative abuse scene, and obtained behavioral data by the animal experiment to clarify why the victim of the date rape drug is seemingly bold after unwlling intake.

Report

(4 results)
  • 2009 Annual Research Report   Final Research Report ( PDF )
  • 2008 Annual Research Report
  • 2007 Annual Research Report
  • Research Products

    (30 results)

All 2009 2008 2007

All Journal Article (15 results) (of which Peer Reviewed: 15 results) Presentation (13 results) Book (2 results)

  • [Journal Article] Single nucleotide polymorphism genotyping by mini-primer allele-specific amplification with universal reporter primers for identification of degraded DNA2009

    • Author(s)
      Asari M, Watanabe S, Matsubara K, Shiono H, Shimizu K.
    • Journal Title

      Anal Biochem. 386

      Pages: 85-90

    • Related Report
      2009 Final Research Report
    • Peer Reviewed
  • [Journal Article] Detection of landiolol using high-performance liquid chromatography/fluorescence : A blood esterase-sensitive ultra-short-acting β1-receptor antagonist2009

    • Author(s)
      Suno M, Kunisawa T, Yamagishi A, Ono T, Yamamoto J, Yamada T, Tasaki Y, Shimizu K, Iwasaki H, Matsubara K.
    • Journal Title

      J Chromatogr B. 877

      Pages: 1705-1708

    • Related Report
      2009 Final Research Report
    • Peer Reviewed
  • [Journal Article] Hot-water-extracts of Polygonum Multiflorum Do Not Induce Any Toxicity but Elicit Limited Beneficial Effects on the Liver in Mice2009

    • Author(s)
      Noda T, Yamada T, Ohkubo T, Omura T, Ono T, Adachi T, Awaya T, Tasaki Y, Shimizu K, Matsubara K.
    • Journal Title

      J Health Sci. 55(5)

      Pages: 720-725

    • NAID

      130000127959

    • Related Report
      2009 Final Research Report
    • Peer Reviewed
  • [Journal Article] Single nucleotide polymorphism genotyping by mini-primer all ele-specific amplification with universal reporter primers for identification of degraded DNA2009

    • Author(s)
      Asari M, Watanabe S, Matsubara K, Shiono H, Shimizu K
    • Journal Title

      Anal Biochem 386

      Pages: 85-90

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Detection of landiolol using high-performance liquid chromatography/fluorescence : A blood esterase-sensitiod esterase-sensitive ultra-short-acting β_1-receptor antagonist.2009

    • Author(s)
      Suno M, Kunisawa T, Yamagishi A, Ono T, Yamamoto J, Yamada T, Tasaki Y, Shimizu K, Iwasaki H, Matsubara K
    • Journal Title

      J Chromatogr B 877

      Pages: 1705-1708

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Hot-water-extracts of Polygonum Multiflorum Do Not Induce Any Toxicity but Elicit Limited Beneficial Effects on the Liver in Mice.2009

    • Author(s)
      Noda T, Yamada T, Ohkubo T, Omura T, Ono T, Adachi T, Awaya T, Tasaki Y, Shimizu K, Matsubara K
    • Journal Title

      J Health Sci 55(5)

      Pages: 720-725

    • NAID

      130000127959

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] 法医学の新しい社会貢献-旭川市高齢者孤立死防止ガイド作成への取り組み-.2009

    • Author(s)
      清水惠子, 佐々木良, 角田康夫, 小泉博一, 浅利優, 大村友博, 間瀬田千香暁, 松原和夫
    • Journal Title

      法医学の実際と研究 52

      Pages: 221-226

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] 大腿骨頭窩の形態を用いた年齢推定法の法医実務における有用性2009

    • Author(s)
      山田ひろみ, 坂上和弘, 渡邊智, 浅利優, 松田都久美, 大村友博, 間瀬田千香暁, 阿久津弘明, 松原和夫, 塩野寛, 清水惠子
    • Journal Title

      法医学の実際と研究 52

      Pages: 11-16

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Differences in tissue distribution of HV2 length heteroplasmy in mitochondrial DNA between mothers and children2008

    • Author(s)
      Asari M, Azumi J, Shimizu K, Shiono H.
    • Journal Title

      Forensic Sci Int. 175

      Pages: 155-159

    • Related Report
      2009 Final Research Report
    • Peer Reviewed
  • [Journal Article] Identification of four charred bodies by DNA parentage testing2008

    • Author(s)
      Azumi J, Asari M, Shimizu K, Shiono H.
    • Journal Title

      Acta Crim Japon. 74(2)

      Pages: 51-57

    • NAID

      10025715428

    • Related Report
      2009 Final Research Report
    • Peer Reviewed
  • [Journal Article] An autopsy case of sudden death due to acute gastric dilatation without rupture2008

    • Author(s)
      Watanabe S, Terazawa K, Asari M, Matsubara K, Shiono H, Shimizu K.
    • Journal Title

      Forensic Sci Int. 180

    • Related Report
      2009 Final Research Report
    • Peer Reviewed
  • [Journal Article] Date Rape Drug と健忘2007

    • Author(s)
      清水惠子
    • Journal Title

      旭川医科大学研究フォーラム 7(1)

      Pages: 2-11

    • NAID

      120001025637

    • Related Report
      2009 Final Research Report
    • Peer Reviewed
  • [Journal Article] Utility of haplogroup determination for forensic mtDNA analysis in the Japanese population2007

    • Author(s)
      Asari M, Umetsu K. Adachi N, Azumi J, Shimizu K, Shiono H.
    • Journal Title

      Legal Med. 9

      Pages: 237-240

    • NAID

      10024172740

    • Related Report
      2009 Final Research Report
    • Peer Reviewed
  • [Journal Article] 5-HT_<1A> receptors mediate (+)8-OH-DPAT-stimulation of extracellular signal-regulated kinase (MAP kinase) in vivo in rat hypothalamus : Time dependence and regional differences2007

    • Author(s)
      Crane JW, Shimizu K, Carrasco GA, Garcia F, Jia C, Sullivan NR, D'Souza DN, Zhang Y, Van de Kar LD, Muma NA, Battaglia G.
    • Journal Title

      Brain Res. 1183

      Pages: 51-59

    • Related Report
      2009 Final Research Report
    • Peer Reviewed
  • [Journal Article] Effect of length variations at nucleotide positions 303-315 in human mitochondrial DNA on transcription termination2007

    • Author(s)
      Asari M, Tan Y, Watanabe S, Shimizu K, Shiono H.
    • Journal Title

      Biochem and Biophys Res Commun. 361(3)

      Pages: 641-644

    • Related Report
      2009 Final Research Report
    • Peer Reviewed
  • [Presentation] Meloxicam protects against 1-methyl-4-phenyl pyridinium-induced cell death via phosphatidylinositol 3-kinase/Akt pathway in human dopaminergic neuroblastoma SH-SY5Y cells.2009

    • Author(s)
      Tasaki Y, Okubo T, Yamada T, Omura T, Suno M, Iida S, Satomi M, Sakaguchi T, Asari M, Shimizu K, Matsubara K
    • Organizer
      39^<th> Annual Meeting Society for Neuroscience
    • Place of Presentation
      Chicago
    • Year and Date
      2009-10-19
    • Related Report
      2009 Annual Research Report
  • [Presentation] 二段階PCRを用いた簡便なABO式血液型判定法の開発.2009

    • Author(s)
      浅利優, 間瀬田千香暁, 塩野寛, 清水惠子, 大村友博, 松原和夫
    • Organizer
      第10回日本法医学会学術北日本地方集会法医学談話会第96回例会
    • Place of Presentation
      旭川
    • Year and Date
      2009-09-26
    • Related Report
      2009 Annual Research Report
  • [Presentation] 現行検死制度における問題点-ある虐待事件から-.2009

    • Author(s)
      清水惠子, 浅利優, 間瀬田千香暁, 塩野寛, 郷一知, 大村友博, 松原和夫, 佐々木良, 角田康夫
    • Organizer
      第10回日本法医学会学術北日本地方集会法医学談話会第96回例会
    • Place of Presentation
      旭川
    • Year and Date
      2009-09-25
    • Related Report
      2009 Annual Research Report
  • [Presentation] 新薬学教育6年制における実務実習モデル・コアカリキュラム「中毒医療への貢献」への対応-法医学講座と連携した救急医療における濫用薬物スクリーニングと血中アルコール濃度測定.2009

    • Author(s)
      大村友博, 麻下智加, 田崎嘉一, 飯田慎也, 山本譲, 須野学, 粟屋敏雄, 三好敏之, 松原和夫, 間瀬田千香暁, 浅利優, 清水惠子
    • Organizer
      第10回日本法医学会学術北日本地方集会法医学談話会第96回例会
    • Place of Presentation
      旭川
    • Year and Date
      2009-09-25
    • Related Report
      2009 Annual Research Report
  • [Presentation] 異状死体ってご存知ですか?-日本の死因究明制度の問題点と最近の動向-.2009

    • Author(s)
      清水惠子
    • Organizer
      北海道臨床衛生検査技師会 旭川地区会 学術講演会
    • Place of Presentation
      旭川
    • Year and Date
      2009-09-11
    • Related Report
      2009 Annual Research Report
  • [Presentation] 胸水および心臓血の生化学マーカーからの溺水診断.2009

    • Author(s)
      渡邊智, 清水惠子, 片田竜一, 水尾圭祐, 西谷陽子, 松本博志
    • Organizer
      第93次日本法医学会学術全国集会
    • Place of Presentation
      大阪
    • Year and Date
      2009-05-14
    • Related Report
      2009 Annual Research Report
  • [Presentation] 15座位のSTR解析により低い尤度比を示した身元確認のためのDNA鑑定事例.2009

    • Author(s)
      浅利優, 大村友博, 間瀬田千香暁, 松原和夫, 塩野寛, 清水惠子
    • Organizer
      第93次日本法医学会学術全国集会
    • Place of Presentation
      大阪
    • Year and Date
      2009-05-14
    • Related Report
      2009 Annual Research Report
  • [Presentation] 大腿骨頭窩の形態を用いた年齢推定法の法医実務における有用性.2009

    • Author(s)
      山田ひろみ, 清水惠子, 浅利優, 広瀬保江, 松田都久美, 大村友博, 間瀬田千香暁, 松原和夫, 塩野寛, 坂上和弘
    • Organizer
      第93次日本法医学会学術全国集会
    • Place of Presentation
      大阪
    • Year and Date
      2009-05-14
    • Related Report
      2009 Annual Research Report
  • [Presentation] Meloxicam protects against 1-methyl-4-phenyl pyridinium-induced cell death via phosphatidylinositol 3-kinase/Akt pathway in human dopaminergic neuroblastoma SH-SY5Y cells2009

    • Author(s)
      Tasaki Y, Okubo T, Yamada T, Omura T, Suno M, Iida S, Satomi M, Sakaguchi T, Asari M, Shimizu K, Matsubara K.
    • Organizer
      39^<th> Annual Meeting Society for Neuroscience
    • Place of Presentation
      Chicago
    • Related Report
      2009 Final Research Report
  • [Presentation] 胸水および心臓血の生化学マーカーからの溺水診断2009

    • Author(s)
      渡邊智, 清水惠子, 片田竜一, 水尾圭祐, 西谷陽子, 松本博志
    • Organizer
      第93次日本法医学会学術全国集会. 日本法医学雑誌.63(1) : p64
    • Place of Presentation
      大阪
    • Related Report
      2009 Final Research Report
  • [Presentation] 15座位のSTR解析により低い尤度比を示した身元確認のためのDNA鑑定事例2009

    • Author(s)
      浅利優, 大村友博, 間瀬田千香暁, 松原和夫, 塩野寛, 清水惠子
    • Organizer
      第93次日本法医学会学術全国集会. 日本法医学雑誌.63(1) : p75
    • Place of Presentation
      大阪
    • Related Report
      2009 Final Research Report
  • [Presentation] 大腿骨頭窩の形態を用いた年齢推定法の法医実務における有用性2009

    • Author(s)
      山田ひろみ, 清水惠子, 浅利優, 広瀬保江, 松田都久美, 大村友博, 間瀬田千香暁, 松原和夫, 塩野寛, 坂上和弘
    • Organizer
      第93次日本法医学会学術全国集会. 日本法医学雑誌.63(1) : p95
    • Place of Presentation
      大阪
    • Related Report
      2009 Final Research Report
  • [Presentation] 現行検死制度における問題点-ある虐待事件から-2009

    • Author(s)
      清水惠子, 浅利優, 間瀬田千香暁, 塩野寛, 郷一知, 大村友博, 松原和夫, 佐々木良, 角田康夫
    • Organizer
      第10回日本法医学会学術北日本地方集会法医学談話会第96回例会. プログラム・抄録集 2009 ; p12
    • Place of Presentation
      旭川
    • Related Report
      2009 Final Research Report
  • [Book] 身近な法医学 改訂3版2008

    • Author(s)
      塩野寛, 清水惠子
    • Total Pages
      305
    • Publisher
      南山堂
    • Related Report
      2009 Final Research Report
  • [Book] 生命倫理への招待 改訂第3版2007

    • Author(s)
      塩野寛, 清水惠子
    • Total Pages
      210
    • Publisher
      南山堂
    • Related Report
      2009 Final Research Report

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Published: 2007-04-01   Modified: 2016-04-21  

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