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Rapid screening method for drug and poisonous substances by direct mass spectrometry

Research Project

Project/Area Number 19590687
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeSingle-year Grants
Section一般
Research Field Legal medicine
Research InstitutionNational Research Institute of Police Science

Principal Investigator

INOUE Hiroyuki  National Research Institute of Police Science, 法科学第三部, 室長 (40159992)

Co-Investigator(Kenkyū-buntansha) 岩田 祐子 (岩田 佑子)  科学警察研究所, 法科学第三部, 主任研究官 (20356190)
Project Period (FY) 2007 – 2008
Project Status Completed (Fiscal Year 2008)
Budget Amount *help
¥2,860,000 (Direct Cost: ¥2,200,000、Indirect Cost: ¥660,000)
Fiscal Year 2008: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Fiscal Year 2007: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
Keywords乱用薬物 / スクリーニング / 質量分析計 / 尿 / 覚せい剤 / MDMA / 医薬品 / 法中毒学
Research Abstract

:直接導入型質量分析計を用いて、エクスタシー錠(MDMA含有錠剤、アンフェタミン及びカフェイン含有錠剤等)や医薬品錠剤(アセトアミノフェン、ジアゼパム等含有)中の成分を迅速に判定する手法を開発した。
また、薬物添加尿についても適用可能であった。本法は、遺留試料や尿試料からの薬毒物スクリーニング法として利用可能であると考えられた。
また、シルデナフィル関連化合物の分析法や覚せい剤の迅速な定量分析法を開発した。

Report

(3 results)
  • 2008 Annual Research Report   Final Research Report ( PDF )
  • 2007 Annual Research Report
  • Research Products

    (10 results)

All 2008

All Journal Article (3 results) (of which Peer Reviewed: 3 results) Presentation (7 results)

  • [Journal Article] Simple and simultaneous detection of methamphetamine and dimethyl sulfone in crystalline methamphetamine seizures by fast gas chromatography2008

    • Author(s)
      Inoue, H., Kuwayama, K., Iwata, Y. T., Kanamori, T., Tsujikawa, K., Miyaguchi, H.
    • Journal Title

      Forensic Toxicology 26

      Pages: 19-22

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Characterization and Profiling of Methamphetamine Seizures2008

    • Author(s)
      Inoue, H., Iwata, Y. T., Kuwayama, K.
    • Journal Title

      Journal of Health Science 54

      Pages: 615-622

    • NAID

      110007005213

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Chemical profile of sildenafil and related compounds2008

    • Author(s)
      Inoue, H, et. al.
    • Journal Title

      日本法科学技術学会誌 13

      Pages: 73-82

    • NAID

      130004942620

    • Related Report
      2007 Annual Research Report
    • Peer Reviewed
  • [Presentation] 警察関連領域における薬毒物鑑定2008

    • Author(s)
      井上博之
    • Organizer
      第1回関西中毒分析研究会
    • Place of Presentation
      大阪府吹田市
    • Year and Date
      2008-09-06
    • Related Report
      2008 Annual Research Report 2008 Final Research Report
  • [Presentation] Rapid and direct analysis of MDMA tablets by atmospheric pressure chemical ionization/ion-trap mass spectrometry2008

    • Author(s)
      Inoue, H., Hashimoto, H., Iwata, Y.T., Kanamori, T., Tsujikawa, K., Miyaguchi, H., Kuwayama, K
    • Organizer
      7^<th> International Symposium ADVANCES IN LEGAL MEDICINE
    • Place of Presentation
      大阪市
    • Year and Date
      2008-09-04
    • Related Report
      2008 Final Research Report
  • [Presentation] Rapid and direct analysis of MDMA tablets by atmospheric pressure chemical ionization/ion-trap mass spectrometry2008

    • Author(s)
      Inoue, H., Hashimoto, H., Iwata, Y. T., Kanamori, T., Tsujikawa, K., Miyaguchi, H., Kuwayama, K.
    • Organizer
      7th International Symposium ADVANCES IN LEGAL MEDICINE
    • Place of Presentation
      大阪市
    • Year and Date
      2008-09-04
    • Related Report
      2008 Annual Research Report
  • [Presentation] 乱用薬物の分析に関する研究2008

    • Author(s)
      井上博之
    • Organizer
      日本法中毒学会第27年会
    • Place of Presentation
      東京都品川区
    • Year and Date
      2008-06-13
    • Related Report
      2008 Annual Research Report 2008 Final Research Report
  • [Presentation] Simple and simultaneous detection of methamphetamine and dimethyl sulfone in crystalline methamphetamine seizures by fast gas chromatography2008

    • Author(s)
      Inoue, H., Kuwayama, K., Iwata, Y.T., Kanamori, T., Tsujikawa, K., Miyaguchi, H
    • Organizer
      第46回国際法中毒学会
    • Place of Presentation
      フランス領マルティニーク
    • Year and Date
      2008-06-06
    • Related Report
      2008 Annual Research Report 2008 Final Research Report
  • [Presentation] Simultaneous determination of methamphetamine and dimethyl sulfone in crystalline methamphetamine seizures by fast gas chromatography2008

    • Author(s)
      Inoue, H., Kuwayama, K., Iwata, Y.T., Kanamori, T., Tsujikawa, K., Miyaguchi, H
    • Organizer
      Pittcon2008
    • Place of Presentation
      米国ニューオーリンズ
    • Year and Date
      2008-03-06
    • Related Report
      2008 Final Research Report
  • [Presentation] Simultaneous detemination of methamphetamine and dimethyl sulfone in cstalline methamhetamine seizures by fast gas chromatoaphy2008

    • Author(s)
      Inoue, H, et. al.
    • Organizer
      PITTCON2008
    • Place of Presentation
      米国、ニューオリンズ
    • Year and Date
      2008-03-05
    • Related Report
      2007 Annual Research Report

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Published: 2007-04-01   Modified: 2016-04-21  

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