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Quantitative assessment of pulmonary vasculature and computer-aided diagnosis of pulmonary thromboembolism

Research Project

Project/Area Number 19590883
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeSingle-year Grants
Section一般
Research Field Respiratory organ internal medicine
Research InstitutionChiba University

Principal Investigator

TANABE Nobuhiro  Chiba University, 医学部・附属病院, 講師 (40292700)

Co-Investigator(Kenkyū-buntansha) KASAHARA Yasunori  千葉大学, 大学院・医学研究院, 助教 (60343092)
TAKIGUCHI Yuichi  千葉大学, 医学部・附属病院, 講師 (30272321)
TATSUMI Koichiro  千葉大学, 大学院・医学研究院, 准教授 (10207061)
KURIYAMA Takayuki  千葉大学, 大学院・医学研究院, 教授 (20009723)
NIKI Noboru  徳島大学, ソシオテクノサイエンス研究部, 教授 (80116847)
Co-Investigator(Renkei-kenkyūsha) KASAHARA Yasunori  千葉大学, 医学部・附属病院, 講師 (60343092)
TAKIGUCHI Yuichi  千葉大学, 大学院・医学研究院, 准教授 (30272321)
TATSUMI Koichiro  千葉大学, 大学院・医学研究院, 教授 (10207061)
NIKI Noboru  徳島大学, ソシオテクノサイエンス研究部, 教授 (80116847)
Project Period (FY) 2007 – 2008
Project Status Completed (Fiscal Year 2008)
Budget Amount *help
¥3,380,000 (Direct Cost: ¥2,600,000、Indirect Cost: ¥780,000)
Fiscal Year 2008: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2007: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
Keywords肺血栓塞栓症 / CT / 肺動脈 / 肺高血圧症
Research Abstract

肺血栓塞栓症の3DCTおよびコンピューターを用いた自動解析システムの開発と肺血管の容量の定量を試みた。重症例では非造影CTでも、肺野のモザイクパターン(肺血流の多い部位が白く、少ない部位が黒い)を用いて認識可能であった。造影CTを用いた肺動脈径の評価では、肺動脈の末梢で径が細くなる例ほど、肺動脈圧が上昇した。さらに、肺血管の定量評価システムを開発し、肺血栓塞栓症では肺動脈の容量の低下がみられた。

Report

(3 results)
  • 2008 Annual Research Report   Final Research Report ( PDF )
  • 2007 Annual Research Report
  • Research Products

    (45 results)

All 2009 2008 2007

All Journal Article (19 results) (of which Peer Reviewed: 11 results) Presentation (20 results) Book (6 results)

  • [Journal Article] 慢性血栓塞栓性肺高血圧症2009

    • Author(s)
      田邉信宏
    • Journal Title

      呼吸器症候群(第2版)(日本臨床社)

    • Related Report
      2008 Annual Research Report
  • [Journal Article] 呼吸器疾患 肺循環障害 肺血栓塞栓症2009

    • Author(s)
      田邉信宏
    • Journal Title

      新臨床内化学第9版(医学書院)

    • Related Report
      2008 Annual Research Report
  • [Journal Article] 呼吸器疾患 肺循環障害 原発性肺高血圧症2009

    • Author(s)
      田邉信宏
    • Journal Title

      新臨床内化学第9版(医学書院)

    • Related Report
      2008 Annual Research Report
  • [Journal Article] Gender differences in chronic thromboembolic pulmonary hypertension in Japan2008

    • Author(s)
      Shigeta A, Tanabe N, et.al.
    • Journal Title

      Circ J 72

      Pages: 2069-74

    • NAID

      110006987366

    • Related Report
      2008 Final Research Report
    • Peer Reviewed
  • [Journal Article] Dilatation of bronchial arteries correlates with extent of central disease in patients with chronic thromboembolic pulmonary hypertension2008

    • Author(s)
      Shimizu H, Tanabe N, et.al.
    • Journal Title

      Cir J 72

      Pages: 1136-1141

    • NAID

      110006792068

    • Related Report
      2008 Final Research Report
    • Peer Reviewed
  • [Journal Article] Quantitative evaluation of chronic pulmonary thromboemboli by multislice CT compared with pulsed Tissue Doppler Imaging and its relationship with brain natriuretic peptide2008

    • Author(s)
      Shiina Y, Funabashi N, Fujikawa A, Lee K, Sekine T, Uehara M, Mikami Y, Tanabe N, et.al.
    • Journal Title

      Int J Cardiol 130

      Pages: 505-12

    • Related Report
      2008 Final Research Report
    • Peer Reviewed
  • [Journal Article] Survival and quality of life in peripheral type chronic thromboembolic pulmonary hypertension2008

    • Author(s)
      Yoshimi S, Tanabe N, et.al.
    • Journal Title

      Cir J 72

      Pages: 958-965

    • Related Report
      2008 Final Research Report
    • Peer Reviewed
  • [Journal Article] 慢性肺血栓塞栓症とHLA2008

    • Author(s)
      田邉信宏
    • Journal Title

      分子血管病 9

      Pages: 368-374

    • Related Report
      2008 Annual Research Report 2008 Final Research Report
  • [Journal Article] 慢性血栓塞栓性肺高血圧症2008

    • Author(s)
      田邉信宏
    • Journal Title

      呼吸と循環 56

      Pages: 987-994

    • Related Report
      2008 Annual Research Report 2008 Final Research Report
  • [Journal Article] Gender differences in chronic thromboembolic pulmonary hypertension in Japan.2008

    • Author(s)
      Ayako Shigeta
    • Journal Title

      Circulation Journal 72

      Pages: 2069-2074

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Dilatation of bronchial arteries correlates with extent of central disease in patients with chronic thromboembolic pulmonary hypertension.2008

    • Author(s)
      Hidefumi Shimizu
    • Journal Title

      Circulation Journal 72

      Pages: 1136-1141

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Quantitative evaluation of chronic pulmonary thromboemboli by multislics CT compared with pulsed Tissue Doppler Imaging and its relationship with brain natriuretic peptide.2008

    • Author(s)
      Yumi Shiina
    • Journal Title

      International Journal of Cardiology 130

      Pages: 505-512

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Survival and Quality of life in peripheral type chronic thromboembolic pulmonary hypertension.2008

    • Author(s)
      Seishi Yoshimi
    • Journal Title

      Circulation Journal 72

      Pages: 958-965

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Journal Article] 原発性肺高血圧症2008

    • Author(s)
      田邉信宏
    • Journal Title

      専門医のための薬物療法Q&A循環器(中外医学社)

    • Related Report
      2008 Annual Research Report
  • [Journal Article] Multidetector-row computed tomography management of acute pulmonary embolism2007

    • Author(s)
      Yasui T., Tanabe N., et.al.
    • Journal Title

      Circ J 71

      Pages: 1948-1954

    • NAID

      110006452882

    • Related Report
      2008 Final Research Report
    • Peer Reviewed
  • [Journal Article] 急性肺血栓塞栓症の管理2007

    • Author(s)
      田邉信宏
    • Journal Title

      臨床呼吸生理 39

      Pages: 1-115

    • Related Report
      2008 Final Research Report
  • [Journal Article] Multidetector-row computed tomography management of acutepulmonary embolism2007

    • Author(s)
      Takahiro Yasui
    • Journal Title

      Circulation Journal 71

      Pages: 1948-1954

    • Related Report
      2007 Annual Research Report
    • Peer Reviewed
  • [Journal Article] 急性肺塞栓症患者における深部静脈血栓症診断の現状と問題点2007

    • Author(s)
      佐久間 聖仁
    • Journal Title

      静脈学 18

      Pages: 19-23

    • Related Report
      2007 Annual Research Report
    • Peer Reviewed
  • [Journal Article] 急性肺血栓塞栓症の管理2007

    • Author(s)
      田邉 信宏
    • Journal Title

      臨床呼吸生理 39

      Pages: 111-115

    • Related Report
      2007 Annual Research Report
  • [Presentation] PD-1肺高血圧症の診断と治療の進歩慢性血栓塞栓性肺高血圧症の内科治療2009

    • Author(s)
      田邉信宏
    • Organizer
      第56回日本心臓病学会学術集会
    • Place of Presentation
      東京
    • Year and Date
      2009-09-08
    • Related Report
      2008 Final Research Report
  • [Presentation] モーニングレクチャー肺血栓塞栓症の診断と治療2009

    • Author(s)
      田邉信宏
    • Organizer
      第73回日本循環器学会総会
    • Place of Presentation
      大阪
    • Year and Date
      2009-03-21
    • Related Report
      2008 Final Research Report
  • [Presentation] モーニングレクチャー 肺血栓塞栓症の診断と治療2009

    • Author(s)
      田邉信宏
    • Organizer
      第73回日本循環器学会総会
    • Place of Presentation
      大阪
    • Year and Date
      2009-03-21
    • Related Report
      2008 Annual Research Report
  • [Presentation] 造影CTを用いた肺血栓塞栓症における肺血管の定量評価2009

    • Author(s)
      酒井俊
    • Organizer
      第1回呼吸機能イメージング研究会学術集
    • Place of Presentation
      京都
    • Year and Date
      2009-01-31
    • Related Report
      2008 Annual Research Report
  • [Presentation] キーノートレクチャー肺血栓塞栓症の疫学及び診断2009

    • Author(s)
      田邉信宏
    • Organizer
      第1回呼吸機能イメージング研究会学術集会
    • Place of Presentation
      京都
    • Year and Date
      2009-01-30
    • Related Report
      2008 Final Research Report
  • [Presentation] キーノートレクチャー肺血栓塞栓症の疫学および診断2009

    • Author(s)
      田邉信宏
    • Organizer
      第1回呼吸機能イメージング研究会学術集
    • Place of Presentation
      京都
    • Year and Date
      2009-01-30
    • Related Report
      2008 Annual Research Report
  • [Presentation] 造影CTを用いた肺血栓塞栓症における肺血管の定量評価2009

    • Author(s)
      酒井俊、財田伸介、久保満、河田佳樹、仁木登、田邉信宏, 他
    • Organizer
      第1回呼吸機能イメージング研究会学術集会
    • Place of Presentation
      京都
    • Year and Date
      2009-01-13
    • Related Report
      2008 Final Research Report
  • [Presentation] PD-1肺高血圧症の診断と治療の進歩 慢性血栓塞栓性肺高血圧症の内科治療2008

    • Author(s)
      田邉信宏
    • Organizer
      第56回日本心臓病学会学術集会
    • Place of Presentation
      東京
    • Year and Date
      2008-09-08
    • Related Report
      2008 Annual Research Report
  • [Presentation] 教育講演 23 肺高血圧症の診断と治療2008

    • Author(s)
      田邉信宏
    • Organizer
      第48回日本呼吸器学会学術講演会
    • Place of Presentation
      東京
    • Year and Date
      2008-06-17
    • Related Report
      2008 Final Research Report
  • [Presentation] 教育講演23肺高血圧症の診断と治療2008

    • Author(s)
      田邉信宏
    • Organizer
      第48回日本呼吸器学会学術講演会
    • Place of Presentation
      東京
    • Year and Date
      2008-06-17
    • Related Report
      2008 Annual Research Report
  • [Presentation] 急性肺血栓塞栓症におけるmulti detector-row CT上のmosaic perfusionの頻度とその意義に関する検討2008

    • Author(s)
      外山真一、田邉信宏, 他
    • Organizer
      第48回日本呼吸器学会学術講演会
    • Place of Presentation
      東京
    • Year and Date
      2008-06-16
    • Related Report
      2008 Final Research Report
  • [Presentation] 慢性血栓塞栓性肺高血圧症(CTEPH)の性差とその臨床的特徴について2008

    • Author(s)
      重田文子、田邉信宏, 他
    • Organizer
      第48回日本呼吸器学会学術講演会
    • Place of Presentation
      東京
    • Year and Date
      2008-06-16
    • Related Report
      2008 Final Research Report
  • [Presentation] 急性肺血栓塞栓症におけるmulti detector-row CT上のmasaic perfusionの頻度とその意義に関する検討2008

    • Author(s)
      外山真一
    • Organizer
      第48回日本呼吸器学会学術講演会
    • Place of Presentation
      東京
    • Year and Date
      2008-06-16
    • Related Report
      2008 Annual Research Report
  • [Presentation] 慢性血栓塞栓性高血圧症の重症(CTEPH)の性差とその臨床的特徴について2008

    • Author(s)
      重田文子, 田邉信宏, 他
    • Organizer
      第48回日本呼吸器学会学術講演会
    • Place of Presentation
      東京
    • Year and Date
      2008-06-16
    • Related Report
      2008 Annual Research Report
  • [Presentation] Prevalence of Mosaic Perfusion and Its Course in Acute Pulmonary Thromboembolism by Multidetector-Row CT Pulmonary Angiography2008

    • Author(s)
      Toyama S, Tanabe N, et.al.
    • Organizer
      International Conference
    • Place of Presentation
      American Thoracic Society Tronto
    • Year and Date
      2008-05-18
    • Related Report
      2008 Final Research Report
  • [Presentation] Prevalence of Mosaic Perfusion and Its Course in Acute Pulmonary Thromboembolism by Multidetector-Row CT Pulmonary Angiography.2008

    • Author(s)
      Shinichi Toyama
    • Organizer
      2008 International Conference, American Thoracic Society
    • Place of Presentation
      Toronto
    • Year and Date
      2008-05-18
    • Related Report
      2008 Annual Research Report
  • [Presentation] 急性肺血栓塞栓症 診療のコツ2007

    • Author(s)
      田邉信宏
    • Organizer
      第6回上総アカデミアレスピラトリーフォーラム
    • Place of Presentation
      木更津
    • Year and Date
      2007-10-06
    • Related Report
      2008 Final Research Report
  • [Presentation] 急性肺血栓塞栓症診療のコツ2007

    • Author(s)
      田邉 信宏
    • Organizer
      第6回上総アカデミアレスピラトリーフォーラム
    • Place of Presentation
      上総アカデミア
    • Year and Date
      2007-10-06
    • Related Report
      2007 Annual Research Report
  • [Presentation] Gender differences in chronic thromboembolic pulmonary hypertension in Japan2007

    • Author(s)
      Shigeta, A., Tanabe, N. et.al.
    • Organizer
      17th Annual congress of European Resiratory
    • Place of Presentation
      Society Stockholm
    • Year and Date
      2007-09-18
    • Related Report
      2008 Final Research Report
  • [Presentation] Prediction of Reduction in Pulmonary Vascular Resistance after Pulmonary Thromboendarterectomy2007

    • Author(s)
      Terada, J., Tanabe, N. et.al.
    • Organizer
      International Conference
    • Place of Presentation
      American Thoracic Society San Francisco
    • Year and Date
      2007-05-23
    • Related Report
      2008 Final Research Report
  • [Book] 呼吸器症候群(第2版)II 慢性血栓塞栓性肺高血圧症2009

    • Author(s)
      田邉信宏
    • Publisher
      日本臨床社
    • Related Report
      2008 Final Research Report
  • [Book] 新臨床内科学第9版 第1章 呼吸器疾患 肺循環障害 肺血栓塞栓症2009

    • Author(s)
      田邉信宏、栗山喬之
    • Publisher
      医学書院
    • Related Report
      2008 Final Research Report
  • [Book] 新臨床内科学第9版 第1章 呼吸器疾患 肺循環障害 原発性肺高血圧症2009

    • Author(s)
      田邉信宏、栗山喬之
    • Publisher
      医学書院
    • Related Report
      2008 Final Research Report
  • [Book] 専門医のための薬物療法Q&A循環器 原発性肺高血圧症2008

    • Author(s)
      田邉信宏、栗山喬之
    • Publisher
      中外医学社
    • Related Report
      2008 Final Research Report
  • [Book] 呼吸器疾患最新の治療肺血栓塞栓症2007

    • Author(s)
      田邉信宏、巽浩一郎
    • Publisher
      南江堂
    • Related Report
      2008 Final Research Report
  • [Book] 肺血栓塞栓症 呼吸器疾患最新の治療2007-20092007

    • Author(s)
      田邉 信宏
    • Publisher
      南江堂
    • Related Report
      2007 Annual Research Report

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Published: 2007-04-01   Modified: 2016-04-21  

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