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Molecular analysisi of pediatric T cell malignancies with the emphasis of NOTCH1 gene.

Research Project

Project/Area Number 19591270
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeSingle-year Grants
Section一般
Research Field Pediatrics
Research InstitutionGunma Institute of Public Health and Environmental Sciences

Principal Investigator

PARK Myoung-Ja  Gunma Institute of Public Health and Environmental Sciences, 研究企画係, 研究員 (50450375)

Co-Investigator(Kenkyū-buntansha) HAYASHI Yasuhide  群馬県衛生環境研究所, 研究企画係, 研究員 (30238133)
加藤 政彦  群馬県衛生環境研究所, 感染制御センター, センター長 (30292593)
外松 学  群馬県衛生環境研究所, 調査研究グループ, 研究員 (70251113)
Co-Investigator(Renkei-kenkyūsha) KATO Masahiko  群馬県衛生環境研究所, 研究企画係, 研究員 (30292593)
SOTOMATSU Manabu  群馬県衛生環境研究所, 研究企画係, 研究員 (70251113)
Project Period (FY) 2007 – 2009
Project Status Completed (Fiscal Year 2009)
Budget Amount *help
¥4,420,000 (Direct Cost: ¥3,400,000、Indirect Cost: ¥1,020,000)
Fiscal Year 2009: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2008: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2007: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
Keywords遺伝子 / ゲノム / 癌 / マイクロアレイ / グノム
Research Abstract

Molecular analysisi of pediatric T cell malignancies with the emphasis of NOTCH1 gene.

Report

(4 results)
  • 2009 Annual Research Report   Final Research Report ( PDF )
  • 2008 Annual Research Report
  • 2007 Annual Research Report
  • Research Products

    (229 results)

All 2010 2009 2008 2007 Other

All Journal Article (85 results) (of which Peer Reviewed: 48 results) Presentation (144 results)

  • [Journal Article] Long-term results of Tokyo Children's Cancer Study Group trials for childhood acute lymphoblastic leukemia2010

    • Author(s)
      Tsuchida M, Ohara A, Manabe A, Kumagai M, Shimada H, Kikuchi A, Mori T, Saito M, Akiyama M, Fukushima T, Koike K, Shiobara M, Ogawa C, Kanazawa T, Noguchi Y, Oota S, Okimoto Y, Yabe H, Kajiwara M, Tomizawa D, Ko K, Sugita K, Kaneko T, Maeda M, Inukai T, Goto H, Takahashi H, Isoyama K, Hayashi Y, Hosoya R, Hanada R
    • Journal Title

      Leukemia 24

    • Related Report
      2009 Final Research Report
  • [Journal Article] Long-term results of Tokyo Children's Cancer Study Group trials for childhood acute lymphoblastic leukemia, 1984-1999.2010

    • Author(s)
      Tsuchida M, et al.
    • Journal Title

      Leukemia 24

      Pages: 383-396

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Mixed-lineage-leukemia (MLL) fusion protein collaborates with Ras to induce acute leukemia through aberrant Hox expression and Raf activation.2009

    • Author(s)
      Ono R, Kumagai H, Nakajima H, Hishiya A, Taki T, Horikawa K, Takatsu K, Satoh T, Hayashi Y, Kitamura T, Nosaka T
    • Journal Title

      Leukemia 23

      Pages: 2197-2209

    • Related Report
      2009 Final Research Report
  • [Journal Article] Manifestation of alveolar rhabdomyosarcoma as primary cutaneous lesions in a neonate with Beckwith-Wiedemann syndrome.2009

    • Author(s)
      Kuroiwa M, Sakamoto J, Shimada A, Suzuki N, Hirato J, Park MJ, Sotomatsu M, Hayashi Y
    • Journal Title

      J Pediatr Surg 44

      Pages: 31-35

    • Related Report
      2009 Final Research Report
  • [Journal Article] JAK2V617F mutation-positive childhood essential thrombocythemia associated with cerebral venous sinus thrombosis.2009

    • Author(s)
      Kurosawa H, Okuya M, Matsushita T, Kubota T, Endoh K, Kuwashima S, Hagisawa S, Sato Y, Fukushima K, Sugita K, Okada Y, Park MJ, Hayashi Y, Arisaka O
    • Journal Title

      J Pediatr Hematol Oncol 31

      Pages: 678-680

    • Related Report
      2009 Final Research Report
  • [Journal Article] Gain-of-function of mutated C-CBL tumour suppressor in myeloid neoplasms.2009

    • Author(s)
      Sanada M, Suzuki T, Shih LY, Otsu M, Kato M, Yamazaki S, Tamura A, Honda H, Sakata-Yanagimoto M, Kumano K, Oda H, Yamagata T, Takita J, Gotoh N, Nakazaki K, Kawamata N, Onodera M, Nobuyoshi M, Hayashi Y, Harada H, Kurokawa M, Chiba S, Mori H, Ozawa K, Omine M, Hirai H, Nakauchi H, Koeffler HP, Ogawa S
    • Journal Title

      Nature 460

      Pages: 904-908

    • Related Report
      2009 Final Research Report
  • [Journal Article] Acute megakaryoblastic leukemia in a child with the MLL-AF4 fusion gene.2009

    • Author(s)
      Takita J, Motomura A, Koh K, Ida K, Taki T, Hayashi Y, Igarashi T
    • Journal Title

      Eur J Haematol 83

      Pages: 149-153

    • Related Report
      2009 Final Research Report
  • [Journal Article] Frequent inactivation of A20 in B-cell lymphomas.2009

    • Author(s)
      Kato M, Sanada M, Kato I, Sato Y, Takita J, Takeuchi K, Niwa A, Chen Y, Nakazaki K, Nomoto J, Asakura Y, Muto S, Tamura A, Iio M, Akatsuka Y, Hayashi Y, Mori H, Igarashi T, Kurokawa M, Chiba S, Mori S, Ishikawa Y, Okamoto K, Tobinai K, Nakagama H, Nakahata T, Yoshino T, Kobayashi Y, Ogawa S
    • Journal Title

      Nature 459

      Pages: 712-716

    • Related Report
      2009 Final Research Report
  • [Journal Article] NUP98-NSD3 fusion gene in radiation-associated myelodysplastic syndrome with t(8;11)(p11;p15) and expression pattern of NSD family genes.2009

    • Author(s)
      Taketani T, Taki T, Nakamura H, Taniwaki M, Masuda J, Hayashi Y
    • Journal Title

      Cancer Genet Cytogenet 190

      Pages: 108-112

    • Related Report
      2009 Final Research Report
  • [Journal Article] Possible involvement of RasGRP4 in leukemogenesis.2009

    • Author(s)
      Watanabe-Okochi N, Oki T, Komeno Y, Kato N, Yuji K, Ono R, Harada Y, Harada H, Hayashi Y, Nakajima H, Nosaka T, Kitaura J, Kitamura T
    • Journal Title

      Int J Hematol 89

      Pages: 470-481

    • NAID

      10025161257

    • Related Report
      2009 Final Research Report
  • [Journal Article] Juvenile myelomonocytic leukemia with t(7;11)(p15;p15) and NUP98-HOXA11 fusion.2009

    • Author(s)
      Mizoguchi Y, Fujita N, Taki T, Hayashi Y, Hamamoto K
    • Journal Title

      Am J Hematol 84

      Pages: 295-297

    • Related Report
      2009 Final Research Report
  • [Journal Article] FBXW7 and NOTCH1 mutations in childhood T cell acute lymphoblastic leukaemia and T cell non-Hodgkin lymphoma.2009

    • Author(s)
      Park MJ, Taki T, Oda M, Watanabe T, Yumura-Yagi K, Kobayashi R, Suzuki N, Hara J, Horibe K, Hayashi Y
    • Journal Title

      Brit J Haematol 145

      Pages: 198-206

    • Related Report
      2009 Final Research Report
  • [Journal Article] Age-associated difference in gene expression of pediatric acute myelomonocytic lineage leukemia (FAB M4 and M5 subtypes) and its correlation with prognosis.2009

    • Author(s)
      Jo A, Tsukimoto I, Ishii E, Asou N, Mitani S, Shimada A, Igarashi T, Hayashi Y, Ichikawa H
    • Journal Title

      Brit J Haematology 144

      Pages: 917-929

    • Related Report
      2009 Final Research Report
  • [Journal Article] Transient abnormal myelopoiesis in a Down syndrome newborn followed by acute myeloid leukemia: identification of the same chromosomal abnormality in both stages.2009

    • Author(s)
      Kitoh T, Taki T, Hayashi Y, Nakamura K, Irino T, Osaka M
    • Journal Title

      Cancer Genet Cytogenet 188

      Pages: 99-102

    • Related Report
      2009 Final Research Report
  • [Journal Article] Mixed-lineage-leukemia (MLL) fusion protein collaborates with Ras to induce acute leukemia through aberrant Hox expression and Raf activation.2009

    • Author(s)
      Ono R, et al.
    • Journal Title

      Leukemia 23

      Pages: 2197-2209

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Manifestation of alveolar rhabdomyosarcoma as primary cutaneous lesions in a neonate with Beckwith-Wiedemann syndrome.2009

    • Author(s)
      Kuroiwa M, et al.
    • Journal Title

      J Pediatr Surg 44

      Pages: 31-35

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] JAK2V617F mutation-positive childhood essential thrombocythemia associated with cerebral venous sinus thrombosis.2009

    • Author(s)
      Kurosawa H, et al.
    • Journal Title

      J Pediatr Hematol Oncol. 31

      Pages: 678-680

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Gain-of-function of mutated C-CBL tumour suppressor in myeloid neoplasms.2009

    • Author(s)
      Sanada M, et al.
    • Journal Title

      Nature 460

      Pages: 904-908

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Acute megakaryoblastic leukemia in a child with the MLL-AF4 fusion gene.2009

    • Author(s)
      Takita J, et al.
    • Journal Title

      Eur J Haematol. 83

      Pages: 149-153

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Frequent inactivation of A20 in B-cell lymphomas.2009

    • Author(s)
      Kato M, et al.
    • Journal Title

      Nature. 459

      Pages: 712-716

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] NUP98-NSD3 fusion gene in radiation-associated myelodysplastic syndrome with t(8 ; 11)(p11 ; p15) and expression pattern of NSD family genes.2009

    • Author(s)
      Taketani T, et al.
    • Journal Title

      Cancer Genet Cytogenet. 190

      Pages: 108-112

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Possible involvement of RasGRP4 in leukemogenesis.2009

    • Author(s)
      Watanabe-Okochi N, et al.
    • Journal Title

      Int J Hematol. 89

      Pages: 470-481

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Juvenile myelomonocytic leukemia with t(7 ; 11)(p15 ; p15) and NUP98-HOXA11 fusion.2009

    • Author(s)
      Mizoguchi Y, et al.
    • Journal Title

      Am J Hematol. 84

      Pages: 295-297

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] FBXW7 and NOTCH1 mutations in childhood T cell acute lymphoblastic leukaemia and T cell non-Hodgkin lymphoma.2009

    • Author(s)
      Park MJ, et al.
    • Journal Title

      Brit J Haematol. 145

      Pages: 198-206

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Age-associated difference in gene expression of pediatric acute myelomonocytic lineage leukemia (FAB M4 and M5 subtypes) and its correlation with prognosis.2009

    • Author(s)
      Jo A, et al.
    • Journal Title

      Brit J Haematology 144

      Pages: 917-929

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Transient abnormal myelopoiesis in a Down syndrome newborn followed by acute myeloid leukemia : identification of the same chromosomal abnormality in both stages.2009

    • Author(s)
      Kitoh T, et al.
    • Journal Title

      Cancer Genet Cytogenet. 188

      Pages: 99-102

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Age-associated difference in gene expression of pediatric acute myelomonocytic lineage leukemia (FAB M4 and M5 subtypes) and its correlation with prognosis2009

    • Author(s)
      Jo A, et al.
    • Journal Title

      Brit J Haematol 144

      Pages: 917-929

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Journal Article] FBXW7 and NOTCH1 mutations in childhood T cell acute lymphoblastic leukaemia and T cell non-Hodgkin lymphoma2009

    • Author(s)
      Park MJ, et al.
    • Journal Title

      Brit J Haematol

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Journal Article] A complex t(1;22;11)(q44;q13;q23) translocation causing MLL-p300 fusion gene in therapy-related acute myeloid leukemia.2008

    • Author(s)
      Ohnishi H, Taki T, Yoshino H, Takita J, Ida K, Ishii M, Nishida K, Hayashi Y, Taniwaki M, Bessho F, Watanabe T
    • Journal Title

      Eur J Haematol 81

      Pages: 475-480

    • Related Report
      2009 Final Research Report
  • [Journal Article] C/EBPalpha and C/EBPvarepsilon induce the monocytic differentiation of myelomonocytic cells with the MLL-chimeric fusion gene.2008

    • Author(s)
      Matsushita H, Nakajima H, Nakamura Y, Tsukamoto H, Tanaka Y, Jin G, Yabe M, Asai S, Ono R, Nosaka T, Sugita K, Morimoto A, Hayashi Y, Hotta T, Ando K, Miyachi H
    • Journal Title

      Oncogene 27

      Pages: 6749-6760

    • Related Report
      2009 Final Research Report
  • [Journal Article] Hemophagocytic lymphohistiocytosis associated with uncontrolled inflammatory cytokinemia and chemokinemia which were caused by systemic anaplastic large cell lymphoma2008

    • Author(s)
      Shimada A, Kato M, Tamura K, Hirato J, Kanegane H, Takechi Y, Park MJ, Sotomatsu M, Hatakeyama S, Hayashi Y
    • Journal Title

      A case report and review of the literature J Pediatr Hematol Oncol 30

      Pages: 785-787

    • Related Report
      2009 Final Research Report
  • [Journal Article] Novel gain-of-function mutation in the extracellular domain of the PDGFRA gene in infant acute lymphoblastic leukemia with t(4;11)(q21;q23).2008

    • Author(s)
      Hiwatari M, Ono R, Taki T, Hishiya A, Ishii E, Kitamura T, Hayashi Y, Nosaka T
    • Journal Title

      Leukemia 22

      Pages: 2279-2280

    • Related Report
      2009 Final Research Report
  • [Journal Article] MNX1-ETV6 fusion gene in an acute megakaryoblastic leukemia and expression of the MNX1 gene in leukemia and normal B cell lines.2008

    • Author(s)
      Taketani T, Taki T, Sako M, Ishii T, Yamaguchi S, Hayashi Y
    • Journal Title

      Cancer Genet Cytogenet 186

      Pages: 115-119

    • Related Report
      2009 Final Research Report
  • [Journal Article] Oncogenic mutations of ALK kinase in neuroblastoma.2008

    • Author(s)
      Chen Y, Takita J, Choi YL, Kato M, Ohira M, Sanada M, Wang L, Soda M, Kikuchi A, Igarashi T, Nakagawara A, Hayashi Y, Mano H, Ogawa S
    • Journal Title

      Nature 455

      Pages: 971-974

    • Related Report
      2009 Final Research Report
  • [Journal Article] Fusion of OTT to BSAC results in aberrant up-regulation of transcriptional activity.2008

    • Author(s)
      Sawada T, Nishiyama C, Kishi T, Sasazuki T, Komazawa-Sakon S, Xue X, Piao JH, Ogata H, Nakayama J, Taki T, Hayashi Y, Watanabe M, Yagita H, Okumura K, Nakano H
    • Journal Title

      J Biol Chem 283

      Pages: 26820-26828

    • Related Report
      2009 Final Research Report
  • [Journal Article] Significance of the complete clearance of peripheral blasts after 7 days of prednisolone treatment in children with acute lymphoblastic leukemia: the Tokyo Children's Cancer Study Group Study L99-15.2008

    • Author(s)
      Manabe A, Ohara A, Hasegawa D, Koh K, Saito T, Kiyokawa N, Kikuchi A, Takahashi H, Ikuta K, Hayashi Y, Hanada R, Tsuchida M
    • Journal Title

      Haematologica 93

      Pages: 1155-1160

    • Related Report
      2009 Final Research Report
  • [Journal Article] Whole genome profiling of chromosomal aberrations in hepatoblastoma using high-density single nucleotide polymorphism genotyping microarrays Cancer Science.2008

    • Author(s)
      Suzuki M, Kato M, Chen Y, Takita J, Sanada M, Nannya Y, Yamamoto G, Takahashi A, Ikeda H, Kuwano H, Ogawa S, Hayashi Y
    • Journal Title

      99

      Pages: 564-570

    • Related Report
      2009 Final Research Report
  • [Journal Article] Identification of the novel AML1 fusion partner gene, LAF4, a fusion partner of MLL, in childhood T-cell acute lymphoblastic leukemia with t(2;21)(q11;q22) by bubble PCR method for cDNA.2008

    • Author(s)
      Chinen Y, Taki T, Nishida K, Shimizu D, Okuda T, Yoshida N, Kobayashi C, Koike K, Tsuchida M, Hayashi Y, Taniwaki M
    • Journal Title

      Oncogene 27

      Pages: 2249-2256

    • Related Report
      2009 Final Research Report
  • [Journal Article] Tandem duplications of MLL and FLT3 are correlated with poor prognoses in pediatric acute myeloid leukemia: A study of the Japanese childhood AML Cooperative Study Group.2008

    • Author(s)
      Shimada A, Taki T, Tabuchi K, Taketani T, Hanada R, Tawa A, Tsuchida M, Horibe K, Tsukimoto I, Hayashi Y
    • Journal Title

      Pediatr Blood Cancer 50

      Pages: 264-269

    • Related Report
      2009 Final Research Report
  • [Journal Article] Clinical features and outcome of MLL gene rearranged acute lymphoblastic leukemia in infants with additional chromosomal abnormalities other than 11q23 translocation.2008

    • Author(s)
      Tauchi H, Tomizawa D, Eguchi M, Eguchi-Ishimae M, Koh K, Hirayama M, Miyamura N, Kinukawa N, Hayashi Y, Horibe K, Ishii E
    • Journal Title

      Leuk Res. 32

      Pages: 1523-1529

    • Related Report
      2009 Final Research Report
  • [Journal Article] Fbxw7 acts as a critical fail-safe against premature loss of hematopoietic stem cells and development of T-ALL.2008

    • Author(s)
      Matsuoka S, Oike Y, Onoyama I, Iwama A, Arai F, Takubo K, Mashimo Y, Oguro H, Nitta E, Ito K, Miyamoto K, Yoshiwara H, Hosokawa K, Nakamura Y, Gomei Y, Iwasaki H, Hayashi Y, Matsuzaki Y, Nakayama K, Ikeda Y, Hata A, Chiba S, Nakayama KI, Suda T
    • Journal Title

      Genes Dev 22

      Pages: 986-991

    • Related Report
      2009 Final Research Report
  • [Journal Article] Mutations of GATA1, FLT3, MLL-partial tandem duplication, NRAS, and RUNX1 genes are not found in a 7-year-old Down syndrome patient with acute myeloid leukemia (FAB-M2) having a good prognosis.2008

    • Author(s)
      Kawamura M, Kaku H, Taketani T, Taki T, Shimada A, Hayashi Y
    • Journal Title

      Cancer Genet Cytogenet 180

      Pages: 74-78

    • Related Report
      2009 Final Research Report
  • [Journal Article] Mutations of GATA1, FLT3, MLL-partial tandem duplication, NRAS, and RUNX1 genes are not found in a 7-year-old Down syndrome patient with acute myeloid leukemia (FAB-M2) having a good prognosis2008

    • Author(s)
      Kawamura M, et al.
    • Journal Title

      Cancer Genet Cytogenet. 180

      Pages: 74-78

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Fbxw7 acts as a critical fail-safe against premature loss of hematopoietic stem cells and development of T-ALL2008

    • Author(s)
      Matsuoka S, et al.
    • Journal Title

      Genes Dev. 22

      Pages: 986-991

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Clinical features and outcome of MLL gene rearranged acute lymphoblastic leukemia in infants with additional chromosomal abnormalities other than 11q23 translocation2008

    • Author(s)
      Tauchi H, et al.
    • Journal Title

      Leuk Res. 32

      Pages: 1523-1529

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Tandem duplications of MLL and FLT3 are correlated with poor prognoses in pediatric acute myeloid leukemia : A study of the Japanese childhood AML Cooperative Study Group2008

    • Author(s)
      Shimada A, et al.
    • Journal Title

      Pediatr Blood Cancer 50

      Pages: 264-269

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Identification of the novel AML1 fusion partner gene, LAF4, a fusion partner of MLL, in childhood T-cell acute lymphoblastic leukemia with t(2;21)(q11;q22) by bubble PCR method for cDNA2008

    • Author(s)
      Chinen Y, et al.
    • Journal Title

      Oncogene 27

      Pages: 2249-2256

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Whole genome profiling of chromosomal aberrations in hepatoblastoma using high-density single nucleotide polymorphism genotyping microarrays2008

    • Author(s)
      Suzuki M, et al.
    • Journal Title

      Cancer Science 99

      Pages: 564-570

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Significance of the complete clearance of peripheral blasts after 7 days of prednisolone treatment in children with acute lymphoblastic leukemia : the Tokyo Children's Cancer Study Group Study L99-152008

    • Author(s)
      Manabe A, et al.
    • Journal Title

      Haematologica 93

      Pages: 1155-1160

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Fusion of OTT to BSAC results in aberrant up-regulation of transcriptional activity2008

    • Author(s)
      Sawada T, et al.
    • Journal Title

      J Biol Chem 283

      Pages: 26820-26828

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Oncogenic mutations of ALK kinase in neuroblastoma2008

    • Author(s)
      Chen Y, et al.
    • Journal Title

      Nature 455

      Pages: 971-974

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Novel gain-of-function mutation in the extracellular domain of the PDGFRA gene in infant acute lymphoblastic leukemia with t(4;11)(q21;q23)2008

    • Author(s)
      Hiwatari M, et al.
    • Journal Title

      Leukemia. 22

      Pages: 2279-2280

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Journal Article] MNX1-ETV6 fusion gene in an acute megakaryoblastic leukemia and expression of the MNX1 gene in leukemia and normal B cell lines2008

    • Author(s)
      Taketani T, et al.
    • Journal Title

      Cancer Genet Cytogenet. 186

      Pages: 115-11

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Hemophagocytic lymphohistiocytosis associated with uncontrolled inflammatory cytokinemia and chemokinemia which were caused by systemic anaplastic large cell lymphoma : A case report and review of the literature2008

    • Author(s)
      Shimada A, et al.
    • Journal Title

      J Pediatr Hematol Oncol 30

      Pages: 785-787

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Journal Article] C/EBPalpha and C/EBPvarepsilon induce the monocytic differentiation of myelomonocytic cells with the MLL-chimeric fusion gene2008

    • Author(s)
      Matsushita H, et al.
    • Journal Title

      Oncogene 27

      Pages: 6749-6760

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Journal Article] A complex t(1;22;11)(q44;q13;q23) translocation causing MLL-p300 fusion gene in therapy-related acute myeloid leukemia2008

    • Author(s)
      Ohnishi H, et al.
    • Journal Title

      Eur J Haematol 81

      Pages: 475-480

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Expression of KIT and PDGFR is associated with a good prognosis in neuroblastoma2008

    • Author(s)
      Shimada A, et al.
    • Journal Title

      Pediatr Blood Cancer 50

      Pages: 213-217

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Transient abnormal myelopoiesis in a Down syndrome newborn followed by acute myeloid leukemia : identification of the same chromosomal abnormality in both stages2008

    • Author(s)
      Kitoh T, et al.
    • Journal Title

      Cancer Genet Cytogenet. 188

      Pages: 99-102

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Tandem duplications of MLL and FLT3 are correlated with poor prognoses in pediatric acute myeloid leukemia:A study of the Japanese childhood AML Cooperative Study Group.2008

    • Author(s)
      Shimada A, Hayashi Y, et. al.
    • Journal Title

      Pediatr Blood Cancer 50

      Pages: 264-269

    • Related Report
      2007 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Expression of KIT and PDGFR is associated with a good prognosis in neuroblastoma.2008

    • Author(s)
      Shimada A, Hayashi Y, et. al.
    • Journal Title

      Pediatr Blood Cancer 50

      Pages: 213-217

    • Related Report
      2007 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Mutations of GATA1,FLT3,MLL-partial tandem duplication,NRAS,and RUNX1 genes are not found in a 7-year-old Down syndrome patient with acute myeloid leukemia(FAB-M2)having a good prognosis.2008

    • Author(s)
      Kawamura M, Hayashi Y, et. al.
    • Journal Title

      Cancer Genet Cytogenet 180

      Pages: 74-78

    • Related Report
      2007 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Identfication of the novel AML1 fusion partner gene,LAF4,a fusion partner of MLL,in childhood T-cell acute lymphoblastic leukemia with t(2;21)(q11;q22)by bubble PCR method for cDNA.2008

    • Author(s)
      Chinen Y, Hayashi Y, et. al.
    • Journal Title

      Oncogene 27

      Pages: 2249-2256

    • Related Report
      2007 Annual Research Report
    • Peer Reviewed
  • [Journal Article] A novel AF10-CALM fusion transcript in gamma/delta-T cell type lymphoblastic lymphoma.2007

    • Author(s)
      Ashihara E, Nakamura S, Inaba T, Taki T, Hayashi Y, Shimazaki C
    • Journal Title

      Am J Hematol 82

      Pages: 859-860

    • Related Report
      2009 Final Research Report
  • [Journal Article] Mutation and expression analyses of the MET and CDKN2A genes in rhabdomyosarcoma with emphasis on MET overexpression.2007

    • Author(s)
      Chen Y, Takita J, Mizuguchi M, Tanaka K, Ida K, Koh K, Igarashi T, Hanada R, Tanaka Y, Park MJ, Hayashi Y
    • Journal Title

      Genes Chromosomes Cancer 46

      Pages: 348-358

    • Related Report
      2009 Final Research Report
  • [Journal Article] Low Frequency of KIT Gene Mutation in Pediatric Acute Myeloid Leukemia with inv(16)(p13q22): A Study of the Japanese Childhood AML Cooperative Study Group.2007

    • Author(s)
      Shimada A, Ichikawa H, Taki T, Kubota C, Hongo T, Sako M, Morimoto A, Tawa A, Tsukimoto I, Hayashi Y
    • Journal Title

      Int J Hematol 86

      Pages: 289-290

    • NAID

      10019798989

    • Related Report
      2009 Final Research Report
  • [Journal Article] Fms-like tyrosine kinase 3 ligand stimulation induces MLL-rearranged leukemia cells into quiescence resistant to antileukemic agents.2007

    • Author(s)
      Furuichi Y, Goi K, Inukai T, Sato H, Nemoto A, Takahashi K, Akahane K, Hirose K, Honna H, Kuroda I, Zhang X, Kagami K, Hayashi Y, Harigaya K, Nakazawa S, Sugita K
    • Journal Title

      Cancer Res 67

      Pages: 9852-9861

    • Related Report
      2009 Final Research Report
  • [Journal Article] AML1 mutation and FLT3-internal tandem duplication in leukemia transformed from myelodysplastic syndrome.2007

    • Author(s)
      Shimada A, Taketani T, Kikuchi A, Hanada R, Arakawa H, Kimura H, Chen Y, Hayashi Y
    • Journal Title

      J Pediatr Hematol Oncol 29

      Pages: 666-667

    • Related Report
      2009 Final Research Report
  • [Journal Article] Outcome of risk-based therapy for infant acute lymphoblastic leukemia with or without an MLL gene rearrangement, with emphasis on late effects: a final report of two consecutive studies, MLL96 and MLL98, of the Japan Infant Leukemia Study Group.2007

    • Author(s)
      Tomizawa D, Koh K, Sato T, Kinukawa N, Morimoto A, Isoyama K, Kosaka Y, Oda T, Oda M, Hayashi Y, Eguchi M, Horibe K, Nakahata T, Mizutani S, Ishii E
    • Journal Title

      Leukemia 21

      Pages: 2258-2263

    • Related Report
      2009 Final Research Report
  • [Journal Article] Identification of a novel fusion gene MLL-MAML2 in secondary acute myelogenous leukemia and myelodysplastic syndrome with inv(11)(q21q23).2007

    • Author(s)
      Nemoto N, Suzukawa K, Shimizu S, Shinagawa A, Takei N, Taki T, Hayashi Y, Kojima H, Kawakami Y, Nagasawa T
    • Journal Title

      Genes Chromosomes Cancer 46

      Pages: 813-819

    • Related Report
      2009 Final Research Report
  • [Journal Article] Japanese childhood AML cooperative study group. N822 mutation of KIT gene was frequent in pediatric acute myeloid leukemia patients with t(8;21) in Japan: a study of the Japanese childhood AML cooperative study group.2007

    • Author(s)
      Shimada A, Taki T, Kubota C, Itou T, Tawa A, Horibe K, Tsuchida M, Hanada R, Tsukimoto I, Hayashi Y
    • Journal Title

      Leukemia 21

      Pages: 2218-2219

    • Related Report
      2009 Final Research Report
  • [Journal Article] No nucleophosmin mutations in pediatric acute myeloid leukemia with normal karyotype: a study of the Japanese Childhood AML Cooperative Study Group.2007

    • Author(s)
      Shimada A, Taki T, Kubota C, Tawa A, Horibe K, Tsuchida M, Hanada R, Tsukimoto I, Hayashi Y
    • Journal Title

      Leukemia 21

      Pages: 1307-1307

    • Related Report
      2009 Final Research Report
  • [Journal Article] Pro-inflammatory cytokinemia is frequently found in Down syndrome patients with hematological disorders.2007

    • Author(s)
      Shimada A, Hayashi Y, Ogasawara M, Park MJ, Katoh M, Minakami H, Kitoh T, Kojima S, Kawa K, Kimura H
    • Journal Title

      Leuk Res 31

      Pages: 1207-1211

    • Related Report
      2009 Final Research Report
  • [Journal Article] Mutation and expression analyses of the MET and CDKN2A genes inrhabdomyosarcoma with emphasis on MET overexpression.2007

    • Author(s)
      Chen Y, Park MJ, Hayashi Y, et. al.
    • Journal Title

      Cancer 46

      Pages: 348-358

    • Related Report
      2007 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Pro-inflammatory cytoknemia is frequently found in Down syndrome patielltswith hematological disorders.2007

    • Author(s)
      Shimada A, Hayashi Y, Park MJ, et. al.
    • Journal Title

      Leuk Res 31

      Pages: 1199-1203

    • Related Report
      2007 Annual Research Report
    • Peer Reviewed
  • [Journal Article] A novel AF10-CALM fusion transcript in gamma/delta-T cell typelymphoblastic lymphoma.2007

    • Author(s)
      Ashihara E, Hayashi Y, et. al.
    • Journal Title

      Am J Hematol 82

      Pages: 859-860

    • Related Report
      2007 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Low frequency of KIT gene mutation in pediatric acute myeloid leukemia with inv(16)(p13q22):A study of the Japanese Childhood AML Cooperative Study Group.2007

    • Author(s)
      Shimtada A, Hayashi Y, et. al.
    • Journal Title

      Iht J Hematol 86

      Pages: 289-290

    • NAID

      10019798989

    • Related Report
      2007 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Fms-like tyrosine kinase 3 ligand stimulation induces MLL-rearrangedleukemia cells into quiescence resistant to antileukemic agents.2007

    • Author(s)
      Furuichi Y, Hayashi Y, et. al.
    • Journal Title

      Cancer Res 67

      Pages: 9852-9861

    • Related Report
      2007 Annual Research Report
    • Peer Reviewed
  • [Journal Article] AML1 mutation and FLT3-intemal tamdem duplication in leukemiatransformed from myelodysplastic syndrome.2007

    • Author(s)
      Shimada A, Hayashi Y, et. al.
    • Journal Title

      J Pediatr Hematol Oncol 29

      Pages: 666-667

    • Related Report
      2007 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Outcome of risk-based therapy for infant acute lymphoblastic leukemia with orwithout an MLL gene rearrangement,with emphasis on late effectS:a final report of two consecutive studies,MLL96 and MLL98,of the Japan Infant Leukemia Study Group.2007

    • Author(s)
      Tomizawa D, Hayashi Y, et. al.
    • Journal Title

      Leukemia 21

      Pages: 2258-2263

    • Related Report
      2007 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Identification of a novel fusion gene MLL-MAML2 in secondary acutemyelogenous leukemia and myelodysplastic syndrome with inv(11)(q21q23).2007

    • Author(s)
      Nemoto N, Hayashi Y, et. al.
    • Journal Title

      Genes Chromosomes Cancer 46

      Pages: 813-819

    • Related Report
      2007 Annual Research Report
    • Peer Reviewed
  • [Journal Article] N822 mutation of KIT gene was frequent in pediatric acute myeloid leukemiapatients with t(8;21)in Japan:a study of the Japanese childhood AML cooperative study group.2007

    • Author(s)
      Shimada A, Hayashi Y, et. al.
    • Journal Title

      Leukemia 21

      Pages: 2218-2219

    • Related Report
      2007 Annual Research Report
    • Peer Reviewed
  • [Journal Article] No nucleophosmin mutations in pediatric acute myeloid leukemia with normal karyotype:a study of the Japanese Childhood AML2007

    • Author(s)
      Shimada A, Hayashi Y, et. al.
    • Journal Title

      Leukemia 21

      Pages: 1307-1307

    • Related Report
      2007 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Identification of side population cells(stem-like cell population)in pediatric solid tumor cell lines.2007

    • Author(s)
      Komuro H, Hayashi Y, et. al.
    • Journal Title

      J Pediatr Surg. 42

      Pages: 2040-2045

    • NAID

      120007138912

    • Related Report
      2007 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Hemophagocytic lymphohistiocytosis associated with uncontrolledinflammatory cytokinemia and chemokinemia which were caused by systemicanaplastic large cell lymphoma:A case repor and review of the literature

    • Author(s)
      Shimada A, Park MJ, Sotomatsu M, Hayashi Y, et. al.
    • Journal Title

      J Pediatr Hematol Oncol (印刷中)

    • Related Report
      2007 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Whole genome profiling of chromosomal aberrations in hepatoblastoma usinghigh-density single nucleotide polymorphism genotyping microarrays

    • Author(s)
      Suzuki M, Hayashi Y, et. al.
    • Journal Title

      Cancer Science (印刷中)

    • Related Report
      2007 Annual Research Report
    • Peer Reviewed
  • [Presentation] 高密度SNPアレイを用いた小児T細胞性腫瘍における網羅的ゲノム解析2010

    • Author(s)
      朴明子, 加藤元博, 清河信敬, 滝田順子, 真田昌, 小川誠司, 林泰秀
    • Organizer
      第8回日本臨床腫瘍学会学術集会
    • Place of Presentation
      東京
    • Year and Date
      2010-03-19
    • Related Report
      2009 Annual Research Report 2009 Final Research Report
  • [Presentation] 診断及び治療に難渋した慢性活動性EBウイルス感染症の一例2010

    • Author(s)
      一之宮健二, 他
    • Organizer
      第20回群馬小児がん研究会
    • Place of Presentation
      前橋
    • Year and Date
      2010-02-26
    • Related Report
      2009 Annual Research Report
  • [Presentation] CITA無効例に対する肝芽腫の治療についての検討2010

    • Author(s)
      朴明子
    • Organizer
      第20回群馬小児がん研究会
    • Place of Presentation
      前橋
    • Year and Date
      2010-02-26
    • Related Report
      2009 Annual Research Report
  • [Presentation] 早期化学療法にて肝腫大縮小を得たIVs神経芽腫2010

    • Author(s)
      大竹紗耶香, 他
    • Organizer
      第20回群馬小児がん研究会
    • Place of Presentation
      前橋
    • Year and Date
      2010-02-26
    • Related Report
      2009 Annual Research Report
  • [Presentation] CITA無効例に対するITECの有効性と治療関連毒性について―肝芽腫5症例の検討2010

    • Author(s)
      朴明子, 外松学, 佐野弘純, 黒岩実, 林泰秀
    • Organizer
      日本小児肝癌スタディグループ(JPLT)研究会2010
    • Place of Presentation
      東京
    • Year and Date
      2010-01-23
    • Related Report
      2009 Final Research Report
  • [Presentation] CITA無効例に対するITECの有効性と治療関連毒性について-肝芽腫5症例の検討2010

    • Author(s)
      朴明子, 他
    • Organizer
      日本小児肝癌スタディグループ(JPLT)研究会2010
    • Place of Presentation
      東京
    • Year and Date
      2010-01-23
    • Related Report
      2009 Annual Research Report
  • [Presentation] Down症候群に伴うtransient abnormal myelopoiesis (TAM)の予後因子についての検討2009

    • Author(s)
      朴明子, 佐野弘純, 小笠原水穂, 嶋田明, 外松学, 井田孔明, 林泰秀
    • Organizer
      第51回日本小児血液学会、第25回日本小児がん学会
    • Place of Presentation
      千葉
    • Year and Date
      2009-11-29
    • Related Report
      2009 Annual Research Report 2009 Final Research Report
  • [Presentation] 新規のリボソームタンパク遺伝子変異を認めたDiamond-Blackfan貧血の一例2009

    • Author(s)
      佐野弘純, 朴明子, 外松学, 今野友貴, 伊藤悦朗, 林泰秀
    • Organizer
      第51回日本小児血液学会、第25回日本小児がん学会
    • Place of Presentation
      千葉
    • Year and Date
      2009-11-29
    • Related Report
      2009 Annual Research Report 2009 Final Research Report
  • [Presentation] NUP98遺伝子再構成を有する小児造血器腫瘍に同定された遺伝子変異とその臨床的意義2009

    • Author(s)
      竹谷健, 他
    • Organizer
      第51回日本小児血液学会、第25回日本小児がん学会
    • Place of Presentation
      千葉
    • Year and Date
      2009-11-29
    • Related Report
      2009 Annual Research Report
  • [Presentation] 術後4ヵ月で再発をきたした上腹部腹壁デスモイド腫瘍の一例2009

    • Author(s)
      若井公子, 他
    • Organizer
      第51回日本小児血液学会、第25回日本小児がん学会
    • Place of Presentation
      千葉
    • Year and Date
      2009-11-29
    • Related Report
      2009 Annual Research Report
  • [Presentation] 初診時にコンパートメント症候群を合併した血友病Aの1乳児例2009

    • Author(s)
      外松学, 他
    • Organizer
      第51回日本小児血液学会、第25回日本小児がん学会
    • Place of Presentation
      千葉
    • Year and Date
      2009-11-29
    • Related Report
      2009 Annual Research Report
  • [Presentation] 悪性奇形腫群腫瘍の治療成績と問題点.第51回日本小児血液学会2009

    • Author(s)
      黒岩実, 西明, 山本英輝, 鈴木則夫, 外松学, 朴明子, 林泰秀
    • Organizer
      第25回日本小児がん学会
    • Place of Presentation
      千葉
    • Year and Date
      2009-11-27
    • Related Report
      2009 Final Research Report
  • [Presentation] 東京小児がん研究グループ急性リンパ性白血病第16次治療研究におけるマーカー中央診断2009

    • Author(s)
      清河信敬, 恩田恵子, 平林真介, 飯島一智, 福島敬, 齋藤正博, 藤本純一郎, 真部淳, 康勝好, 熊谷昌明, 小原明, 林泰秀, 花田良二, 土田昌宏
    • Organizer
      第51回日本小児血液学会、第25回日本小児がん学会
    • Place of Presentation
      千葉
    • Year and Date
      2009-11-27
    • Related Report
      2009 Annual Research Report 2009 Final Research Report
  • [Presentation] TCCSG-L1602治療研究におけるDay8末梢血-芽球数のフローサイトメトリー測定についての評価2009

    • Author(s)
      恩田恵子, 平林真介, 清川信敬, 齋藤正博, 森鉄也, 福島敬, 藤本純一郎, 真部淳, 康勝好, 熊谷昌明, 小原明, 林泰秀, 花田良二, 土田昌宏
    • Organizer
      第51回日本小児血液学会、第25回日本小児がん学会
    • Place of Presentation
      千葉
    • Year and Date
      2009-11-27
    • Related Report
      2009 Annual Research Report 2009 Final Research Report
  • [Presentation] T細胞性急性リンパ性白血病におけるPTENとP13K-AKT経路の遺伝子解析2009

    • Author(s)
      朴明子, 滝智彦, 小田慈, 八木啓子, 小林良二, 鈴木信寛, 原純一, 堀部敬三, 林泰秀
    • Organizer
      第51回日本小児血液学会、第25回日本小児がん学会
    • Place of Presentation
      千葉
    • Year and Date
      2009-11-27
    • Related Report
      2009 Annual Research Report 2009 Final Research Report
  • [Presentation] 21 trisomyと小児急性リンパ性白血病2009

    • Author(s)
      加藤元博, 滝田順子, 朴明子, 真田昌, 川俣紀彦, Claus Bartrum, H Phillip Koeffler, 菊地陽, 五十嵐隆, 小川誠司, 林泰秀
    • Organizer
      第51回日本小児血液学会、第25回日本小児がん学会
    • Place of Presentation
      千葉
    • Year and Date
      2009-11-27
    • Related Report
      2009 Annual Research Report 2009 Final Research Report
  • [Presentation] 神経芽腫における短縮型ALKによる活性化2009

    • Author(s)
      加藤元博, 滝田順子, 陳玉彦, 大木健太郎, 西村力, 真田昌, 井田孔明, 菊地陽, 小川誠司, 林泰秀, 五十嵐隆
    • Organizer
      第51回日本小児血液学会、第25回日本小児がん学会
    • Place of Presentation
      千葉
    • Year and Date
      2009-11-27
    • Related Report
      2009 Annual Research Report 2009 Final Research Report
  • [Presentation] 固形腫瘍におけるALK遺伝子の解析2009

    • Author(s)
      大木健太郎, 滝田順子, 陳玉彦, 西村力, 加藤元博, 金兼弘和, 大喜多肇, 藤本純一郎, 真田昌, 菊地陽, 五十嵐隆, 林泰秀, 小川誠司
    • Organizer
      第51回日本小児血液学会、第25回日本小児がん学会
    • Place of Presentation
      千葉
    • Year and Date
      2009-11-27
    • Related Report
      2009 Annual Research Report 2009 Final Research Report
  • [Presentation] 高密度SNPアレイを用いたユーイング肉腫における網羅的ゲノム解析2009

    • Author(s)
      西村力, 滝田順子, 大木健太郎, 加藤元博, 陳玉彦, 真田昌, 菊地陽, 五十嵐隆, 林泰秀, 小川誠司
    • Organizer
      第51回日本小児血液学会、第25回日本小児がん学会
    • Place of Presentation
      千葉
    • Year and Date
      2009-11-27
    • Related Report
      2009 Annual Research Report 2009 Final Research Report
  • [Presentation] 悪性奇形腫群腫瘍の治療成績と問題点2009

    • Author(s)
      黒岩実, 他
    • Organizer
      第51回日本小児血液学会、第25回日本小児がん学会
    • Place of Presentation
      千葉
    • Year and Date
      2009-11-27
    • Related Report
      2009 Annual Research Report
  • [Presentation] 異なる病理組織像の急性虫垂炎を合併した白血病の2症例2009

    • Author(s)
      橘木浩平, 他
    • Organizer
      第51回日本小児血液学会、第25回日本小児がん学会
    • Place of Presentation
      千葉
    • Year and Date
      2009-11-27
    • Related Report
      2009 Annual Research Report
  • [Presentation] 小児急性骨髄性白血病におけるWT1遺伝子変異と臨床像2009

    • Author(s)
      佐野弘純, 久保田知里, 朴明子, 嶋田明, 外松学, 滝智彦, 田渕健, 多和昭雄, 堀部敬三, 土田昌宏, 花田良二, 月本一郎, 林泰秀
    • Organizer
      第71回日本血液学会
    • Place of Presentation
      京都
    • Year and Date
      2009-10-25
    • Related Report
      2009 Annual Research Report 2009 Final Research Report
  • [Presentation] 小児B細胞性リンパ腫のマイクロアレイを用いたmolecular karyotypingと網羅的発現遺伝子解析2009

    • Author(s)
      清河信敬, 恩田恵子, 飯島一智, 長谷川大輔, 加藤元博, 大喜多肇, 齋藤正博, 森鉄也, 真部淳, 康勝好, 小原明, 林泰秀, 花田良二, 土田昌宏, 中川温子, 小川誠司, 藤本純一郎
    • Organizer
      第71回日本血液学会
    • Place of Presentation
      京都
    • Year and Date
      2009-10-25
    • Related Report
      2009 Final Research Report
  • [Presentation] 小児B細胞性リンパ腫のマイクロァレイを用いたmolecular kalyotypingと網羅的発現遺伝子解析2009

    • Author(s)
      清河信敬, 他
    • Organizer
      第71回日本血液学会
    • Place of Presentation
      京都
    • Year and Date
      2009-10-25
    • Related Report
      2009 Annual Research Report
  • [Presentation] A Japanese pedigree with RUNX1 mutation resulting in FPD/AML2009

    • Author(s)
      Hasegawa D, Ogawa C, Hirabayashi S, Park MJ, Hayashi Y, Manabe A, Hosoya R
    • Organizer
      第71回日本血液学会
    • Place of Presentation
      京都
    • Year and Date
      2009-10-24
    • Related Report
      2009 Final Research Report
  • [Presentation] Clinical sighificance of somatic mutations in hematological malignancies with NUP98-fusion genes2009

    • Author(s)
      Taketani T, Taki T, Fukada S, Yamaguchi S, Hayashi Y
    • Organizer
      第71回日本血液学会
    • Place of Presentation
      京都
    • Year and Date
      2009-10-24
    • Related Report
      2009 Final Research Report
  • [Presentation] Molecular allelo-karyotype of adult acute lymphoblastic leukemia(ALL) and pediatric ALL2009

    • Author(s)
      Okubo J, Kato M, Takita J, Sanada M, Ohki K, Nishimura R, Kikuchi A, Igarashi T, Hayashi Y, Ogawa S
    • Organizer
      第71回日本血液学会
    • Place of Presentation
      京都
    • Year and Date
      2009-10-24
    • Related Report
      2009 Final Research Report
  • [Presentation] A Japanese pedigree with RUNX1 mutation resulting in FPD/AML.2009

    • Author(s)
      Hasegawa D, et al.
    • Organizer
      第71回日本血液学会
    • Place of Presentation
      京都
    • Year and Date
      2009-10-24
    • Related Report
      2009 Annual Research Report
  • [Presentation] Clinical sighificance of somatic mutations in hematological malignancies with NUP98-fusion genes.2009

    • Author(s)
      Taketani T, et al.
    • Organizer
      第71回日本血液学会
    • Place of Presentation
      京都
    • Year and Date
      2009-10-24
    • Related Report
      2009 Annual Research Report
  • [Presentation] Molecular allelo-karyotype of adult acute lymphoblastic leukemia(ALL) and pediatric ALL.2009

    • Author(s)
      Okubo J, et al.
    • Organizer
      第71回日本血液学会
    • Place of Presentation
      京都
    • Year and Date
      2009-10-24
    • Related Report
      2009 Annual Research Report
  • [Presentation] 東京小児がん研究グループにて1981年から1999年の5つの研究に登録された小児急性リンパ性白血病2035例の長期追跡結果2009

    • Author(s)
      土田昌宏, 小原明, 花田良二, 真部淳, 熊谷昌明, 高橋浩之, 金沢崇, 藤村純也, 富澤大輔, 康勝好, 嶋田博之, 森鉄也, 後藤裕明, 福島敬, 小池和俊, 野口靖, 小川千登世, 犬飼岳史, 福島啓太郎, 塩原正明, 加藤陽子, 前田美穂, 菊地陽, 梶原道子, 矢部晋正, 外松学, 太田節雄, 磯山恵一, 金子隆, 林泰秀
    • Organizer
      第71回日本血液学会
    • Place of Presentation
      京都
    • Year and Date
      2009-10-23
    • Related Report
      2009 Annual Research Report 2009 Final Research Report
  • [Presentation] Genome-wide analysis of pediatric T-cell acute lymphoblastic leukemia2009

    • Author(s)
      Park MJ, Kato M, Kiyokawa N, Sanada M, Takita J, Ogawa S, Hayashi Y
    • Organizer
      第71回日本血液学会
    • Place of Presentation
      京都
    • Year and Date
      2009-10-23
    • Related Report
      2009 Final Research Report
  • [Presentation] Genome-wide analysis of pediatric T-cell acute lymphoblastic leukemia.2009

    • Author(s)
      Park MJ, et al.
    • Organizer
      第71回日本血液学会
    • Place of Presentation
      京都
    • Year and Date
      2009-10-23
    • Related Report
      2009 Annual Research Report
  • [Presentation] 各種腫瘍における高密度SNPアレイを用いた網羅的ゲノムプロファイリング2009

    • Author(s)
      松原亜以子, 加藤元博, 真田昌, 滝田順子, 千葉滋, 林泰秀, 小俣政男, 小林幸夫, 渡邉俊樹, 石川雄一, 吉野正, 小川誠司
    • Organizer
      第68回日本癌学会学術総会
    • Place of Presentation
      横浜
    • Year and Date
      2009-10-03
    • Related Report
      2009 Annual Research Report 2009 Final Research Report
  • [Presentation] 小児固形腫瘍におけるALK遺伝子の増幅と変異2009

    • Author(s)
      滝田順子, 大木健太郎, 西村力, 加藤元博, 陳玉彦, 真田昌, 金兼弘和, 大喜多肇, 藤本純一郎, 菊地陽, 五十嵐隆, 林泰秀, 小川誠司
    • Organizer
      第68回日本癌学会学術総会
    • Place of Presentation
      横浜
    • Year and Date
      2009-10-03
    • Related Report
      2009 Annual Research Report 2009 Final Research Report
  • [Presentation] 小児T細胞型急性リンパ性白血病における網羅的ゲノム解析2009

    • Author(s)
      朴明子, 加藤元博, 清河信敬, 真田昌, 滝田順子, 小川誠司, 林泰秀
    • Organizer
      第68回日本癌学会学術総会
    • Place of Presentation
      横浜
    • Year and Date
      2009-10-03
    • Related Report
      2009 Annual Research Report 2009 Final Research Report
  • [Presentation] 小児固形腫瘍におけるALK阻害剤の感受性2009

    • Author(s)
      本村あい, 滝田順子, 大木健太郎, 西村力, 加藤元博, 陳玉彦, 真田昌, 菊地陽, 五十嵐隆, 林泰秀, 小川誠司
    • Organizer
      第68回日本癌学会学術総会
    • Place of Presentation
      横浜
    • Year and Date
      2009-10-03
    • Related Report
      2009 Annual Research Report 2009 Final Research Report
  • [Presentation] ユーイング肉腫における高密度SNPアレイによる網羅的遺伝子解析2009

    • Author(s)
      西村力, 滝田順子, 大木健太郎, 加藤元博, 陳玉彦, 真田昌, 菊地陽, 五十嵐隆, 林泰秀, 小川誠司
    • Organizer
      第68回日本癌学会学術総会
    • Place of Presentation
      横浜
    • Year and Date
      2009-10-01
    • Related Report
      2009 Annual Research Report 2009 Final Research Report
  • [Presentation] 神経芽細胞腫のALK遺伝子異常によるALKキナーゼ活性の以上増幅2009

    • Author(s)
      大木健太郎, 滝田順子, 西村力, 加藤元博, 陳玉彦, 真田昌, 菊地陽, 五十嵐隆, 林泰秀, 小川誠司
    • Organizer
      第68回日本癌学会学術総会
    • Place of Presentation
      横浜
    • Year and Date
      2009-10-01
    • Related Report
      2009 Annual Research Report 2009 Final Research Report
  • [Presentation] Opsoclonus-myoclonus症候群を契機に診断された神経芽腫の一例2009

    • Author(s)
      佐野弘純, 他
    • Organizer
      第19回群馬小児がん研究会
    • Place of Presentation
      前橋
    • Year and Date
      2009-08-21
    • Related Report
      2009 Annual Research Report
  • [Presentation] 若年性骨髄単球性白血病(JMML)のゲノム解析2009

    • Author(s)
      加藤元博, 他
    • Organizer
      厚生労働省がん研究助成金/厚生労働科学研究費補助金藤本班・堀部班・石田班合同班会議
    • Place of Presentation
      名古屋
    • Year and Date
      2009-06-20
    • Related Report
      2009 Annual Research Report
  • [Presentation] T細胞性急性リンパ性白血病におけるPTENとPI3K-AKT経路の遺伝子解析2009

    • Author(s)
      朴明子, 他
    • Organizer
      厚生労働省がん研究助成金/厚生労働科学研究費補助金藤本班・堀部班・石田班合同班会議
    • Place of Presentation
      名古屋
    • Year and Date
      2009-06-20
    • Related Report
      2009 Annual Research Report
  • [Presentation] MLPA (Multiple Ligation-dependent Probe Amplification)法による染色体全サブトロメア微細構造異常の網羅的解析2009

    • Author(s)
      吉橋博史, 他
    • Organizer
      第181回日本小児科学会群馬地方会講話会
    • Place of Presentation
      高崎
    • Year and Date
      2009-06-13
    • Related Report
      2009 Annual Research Report
  • [Presentation] RUNX1変異を伴ったfamilial platelet disorder with propensity to acute myelogeneous leukemia(FPD/AML)一家系2009

    • Author(s)
      長谷川大輔, 小川千登世, 神谷尚宏, 小澤美和, 真部淳, 細谷亮太, 久保田知里, 朴明子, 林泰秀
    • Organizer
      第6回北関東小児がんセミナー
    • Place of Presentation
      高崎
    • Year and Date
      2009-05-16
    • Related Report
      2009 Final Research Report
  • [Presentation] 小児固形腫瘍におけるALK遺伝子の解析2009

    • Author(s)
      滝田順子, 他
    • Organizer
      第6回北関東小児がんセミナー
    • Place of Presentation
      高崎
    • Year and Date
      2009-05-16
    • Related Report
      2009 Annual Research Report
  • [Presentation] RUNX1変異を伴ったfamilial platelet disorder with propensity to acute myelogene ous leukemia (FPD/AML)-家系2009

    • Author(s)
      長谷川大輔, 他
    • Organizer
      第6回北関東小児がんセミナー
    • Place of Presentation
      高崎
    • Year and Date
      2009-05-16
    • Related Report
      2009 Annual Research Report
  • [Presentation] 神経芽腫におけるALK遺伝子の解析2009

    • Author(s)
      滝田順子, 陳玉彦, 加藤元博, 大平美紀, 菊地陽, 中川原章, 野間博行, 林泰秀, 五十嵐隆, 小川誠司
    • Organizer
      第112回日本小児科学会学術集会
    • Place of Presentation
      奈良
    • Year and Date
      2009-04-18
    • Related Report
      2009 Annual Research Report 2009 Final Research Report
  • [Presentation] 小児がんにおける網羅的なLoss of heterozygosity(LOH)解析2009

    • Author(s)
      加藤元博, 滝田順子, 陳玉彦, 真田昌, 大木健太郎, 滝智彦, 菊地陽, 林泰秀, 小川誠司, 五十嵐隆
    • Organizer
      第112回日本小児科学会学術集会
    • Place of Presentation
      奈良
    • Year and Date
      2009-04-18
    • Related Report
      2009 Final Research Report
  • [Presentation] 小児がんにおける網羅的なLoss of heterozygosity (LOH)解析2009

    • Author(s)
      加藤元博, 他
    • Organizer
      第112回日本小児科学会学術集会
    • Place of Presentation
      奈良
    • Year and Date
      2009-04-18
    • Related Report
      2009 Annual Research Report
  • [Presentation] 超高密度オリゴヌクレオチドアレイを用いた小児横紋筋肉腫における網羅的ゲノム解析2009

    • Author(s)
      大木健太郎, 滝田順子, 加藤元博, 陳玉彦, 真田昌, 林泰秀, 五十嵐隆, 小川誠司
    • Organizer
      第112回日本小児科学会学術集会
    • Place of Presentation
      奈良
    • Year and Date
      2009-04-17
    • Related Report
      2009 Annual Research Report 2009 Final Research Report
  • [Presentation] Notch-1変異を認めたMyeloid/NK白血病の一例2009

    • Author(s)
      柴徳夫, 金澤崇, 朴明子, 田村一志, 塚田昌大, 小板橋実希子, 林泰秀, 荒川浩一
    • Organizer
      第18回群馬小児がん研究会
    • Place of Presentation
      前橋
    • Year and Date
      2009-02-27
    • Related Report
      2009 Final Research Report
  • [Presentation] 小児固形腫瘍の診断および治療効果判定におけるMRI拡散強調画像の有効性について2009

    • Author(s)
      佐野弘純, 他
    • Organizer
      第51回日本小児血液学会、第25回日本小児がん学会
    • Place of Presentation
      千葉
    • Related Report
      2009 Annual Research Report
  • [Presentation] 神経芽腫における網羅的ゲノム解析2008

    • Author(s)
      加藤元博, 他
    • Organizer
      第5回北関東がんセミナー
    • Place of Presentation
      高崎
    • Year and Date
      2008-05-10
    • Related Report
      2008 Annual Research Report
  • [Presentation] FBW7 and NOTCH1 mutations in childhood T-cell acute lymphoblastic leukemia and T-cell non-Hodgkin's lymphoma ; a Japan association of childhood leukemia study group.2008

    • Author(s)
      Park MJ, Taki T, Oda M, Yagi K, Kobayashi R, Suzuki N, Hara J, Horibe K, Hayashi Y
    • Organizer
      48th British Society for Haematology
    • Place of Presentation
      Grasgow U.K.
    • Related Report
      2009 Final Research Report
  • [Presentation] 好酸球増多症候群/好酸球性白血病マウスモデルの検討2008

    • Author(s)
      山田佳之, 林泰秀
    • Organizer
      第111回日本小児科学会学術集会
    • Place of Presentation
      東京
    • Related Report
      2009 Final Research Report 2008 Annual Research Report
  • [Presentation] 横紋筋肉腫における網羅的ゲノム解析2008

    • Author(s)
      滝田順子, 陳玉彦, 加藤元博, 山本豪, 南谷泰仁, 真田昌, 菊地陽, 小川誠司, 林泰秀, 五十嵐隆
    • Organizer
      第111回日本小児科学会学術集会
    • Place of Presentation
      東京
    • Related Report
      2009 Final Research Report 2008 Annual Research Report
  • [Presentation] マイクロアレイを用いた乳児白血病の網羅的ゲノム・エピゲノム解析2008

    • Author(s)
      加藤元博, 滝田順子, 陳玉彦, 康勝好, 井田孔明, 菊地陽, 滝智彦, 林泰秀, 小川誠司, 五十嵐隆
    • Organizer
      第111回日本小児科学会学術集会
    • Place of Presentation
      東京
    • Related Report
      2009 Final Research Report 2008 Annual Research Report
  • [Presentation] 若年性急性骨髄単球性白血病における網羅的ゲノム・メチル化解析2008

    • Author(s)
      陳玉彦, 加藤元博, 滝田順子, 中村文彦, 山本豪, 真田昌, 南谷泰仁, 小川誠司, 林泰秀, 五十嵐隆
    • Organizer
      第111回日本小児科学会学術集会
    • Place of Presentation
      東京
    • Related Report
      2009 Final Research Report 2008 Annual Research Report
  • [Presentation] Moecular allelo-karyotyping of neuroblastoma using high-resolution single nucleotide polymorphism genomic microarrays2008

    • Author(s)
      Kato M, Takita J, Ohira M, Chen YY, Sanada M, Kikuchi A, Igarashi1 T, Nakagawara A, Hayashi Y, Ogawa S
    • Organizer
      Advances in Neuroblastoma Research(ANR)2008
    • Place of Presentation
      千葉
    • Related Report
      2009 Final Research Report
  • [Presentation] Genome-wide analysis of epigenetic abnormalities in neuroblastoma using oligonucleotide tiling array2008

    • Author(s)
      Kato M, Iio M, Takita J, Chen YY, Nakamura F, Sanada M, Watanabe T, Igarashi T, Ogawa S, Hayashi Y
    • Organizer
      Advances in Neuroblastoma Research (ANR)2008
    • Place of Presentation
      千葉
    • Related Report
      2009 Final Research Report
  • [Presentation] High-resolution copy number analysis and identification of target genes in neuroblastoma using high-density SNP-genotyping microarrays2008

    • Author(s)
      Takita J, Chen YY, Kato M, Yamamoto G, Sanada M, Nannya Y, Kikuchi A, Igarashi T, Ogawa S, Hayashi Y
    • Organizer
      Advances in Neuroblastoma Research (ANR)2008
    • Place of Presentation
      千葉
    • Related Report
      2009 Final Research Report
  • [Presentation] Expression of KIT and PDGFR is associated with a good clinical outcome in neuroblastoma2008

    • Author(s)
      Sano H, Shimada A, Hirato J, Kuroiwa M, Kikuchi A, Hanada R, Wakai K, Park MJ, Sotomatsu M, Hayashi Y
    • Organizer
      Advances in Neuroblastoma Research (ANR)2008
    • Place of Presentation
      千葉
    • Related Report
      2009 Final Research Report
  • [Presentation] 11q23転座以外の付加的染色体異常を認めたMLL再構成乳児急性リンパ性白血病の臨床的特徴及び予後2008

    • Author(s)
      田内久道, 富澤大輔, 江口真理子, 石前峰斉, 康勝好, 平山雅浩, 宮村能子, 絹川直子, 林泰秀, 堀部敬三, 石井榮一
    • Organizer
      第70回日本血液学会総会
    • Place of Presentation
      京都
    • Related Report
      2009 Final Research Report 2008 Annual Research Report
  • [Presentation] 小児ALLに対する化学療法早期の有効性と安全性の検討:TCCSG ALL L04-16研究2008

    • Author(s)
      小原明, 真部淳, 牧本敦, 康勝好, 小川千登世, 磯山恵一, 杉田憲一, 杉田完爾, 野口靖, 太田節雄, 前田美穂, 矢部普正, 金子隆, 熊谷昌明, 梶原道子, 高橋浩之, 菊地陽, 嶋田博之, 外松学, 福島敬, 齋藤正博, 林泰秀, 花田良二, 土田昌宏
    • Organizer
      第70回日本血液学会総会
    • Place of Presentation
      京都
    • Related Report
      2009 Final Research Report
  • [Presentation] CD10の発現とMLL再構成が通常のパターンと異なった乳児急性リンパ性白血病の2症例2008

    • Author(s)
      佐野弘純, 朴明子, 山田佳之, 外松学, 田村一志, 金澤崇, 林泰秀
    • Organizer
      第70回日本血液学会総会
    • Place of Presentation
      京都
    • Related Report
      2009 Final Research Report 2008 Annual Research Report
  • [Presentation] 小児AML with multilineage dysplasiaの2例2008

    • Author(s)
      朴明子, 佐野弘純, 山田佳之, 外松学, 菊地陽, 花田良二, 林泰秀
    • Organizer
      第70回日本血液学会総会
    • Place of Presentation
      京都
    • Related Report
      2009 Final Research Report
  • [Presentation] 超高密度SNPアレイを用いたMLL再構成陽性小児白血病におけるmolecular allelo-karyotyping2008

    • Author(s)
      滝田順子, 加藤元博, 陳玉彦, 大木健太郎, 山本豪, 真田昌, 南谷泰仁, 滝智彦, 五十嵐隆, 林泰秀, 小川誠司
    • Organizer
      第70回日本血液学会総会
    • Place of Presentation
      京都
    • Related Report
      2009 Final Research Report
  • [Presentation] 小児急性骨髄球性白血病におけるMolecular allelo-karyotyping2008

    • Author(s)
      大木健太郎, 滝田順子, 加藤元博, 陳玉彦, 山本豪, 真田昌, 南谷泰仁, 菊地陽, 林泰秀, 五十嵐隆, 小川誠司
    • Organizer
      第70回日本血液学会総会
    • Place of Presentation
      京都
    • Related Report
      2009 Final Research Report
  • [Presentation] 高密度SNPマイクロアレイを用いた本邦の小児急性リンパ芽球性白血病のmolecular karyotyping2008

    • Author(s)
      清河信敬, 加藤元博, 藤本純一郎, 宮川世志幸, 恩田恵子, 大喜多肇, 齋藤正博, 牧本敦, 真部淳, 康勝好, 小原明, 林泰秀, 花田良二, 土田昌宏, 小川誠司
    • Organizer
      第70回日本血液学会総会
    • Place of Presentation
      京都
    • Related Report
      2009 Final Research Report
  • [Presentation] 小児急性骨髄性白血病における網羅的ゲノム解析2008

    • Author(s)
      大木健太郎, 滝田順子, 加藤元博, 陳玉彦, 真田昌, 菊地陽, 小川誠司, 五十嵐隆, 林泰秀
    • Organizer
      第67回日本癌学会
    • Place of Presentation
      名古屋
    • Related Report
      2009 Final Research Report 2008 Annual Research Report
  • [Presentation] 神経芽腫における網羅的ゲノム解析および標的遺伝子の同定2008

    • Author(s)
      陳玉彦, 滝田順子, 加藤元博, 大平美紀, 真田昌, 菊地陽, 五十嵐隆, 中川原明, 林泰秀, 小川誠司
    • Organizer
      第67回日本癌学会
    • Place of Presentation
      名古屋
    • Related Report
      2009 Final Research Report 2008 Annual Research Report
  • [Presentation] 横紋筋肉腫における網羅的ゲノム解析2008

    • Author(s)
      滝田順子, 加藤元博, 陳玉彦, 山本豪, 真田昌, 南谷泰仁, 大木健太郎, 菊地陽, 五十嵐隆, 林泰秀, 小川誠司
    • Organizer
      第67回日本癌学会
    • Place of Presentation
      名古屋
    • Related Report
      2009 Final Research Report 2008 Annual Research Report
  • [Presentation] 悪性リンパ腫における網羅的ゲノム解析2008

    • Author(s)
      加藤元博, 中崎久美, 竹内健吾, 真田昌, 千葉滋, 石川雄一, 滝田順子, 林泰秀, 森茂郎, 小林幸夫, 黒川峰夫, 小川誠司
    • Organizer
      第67回日本癌学会
    • Place of Presentation
      名古屋
    • Related Report
      2009 Final Research Report 2008 Annual Research Report
  • [Presentation] 小児T細胞型急性リンパ性白血病におけるPTEN遺伝子の解析2008

    • Author(s)
      朴明子, 滝智彦, 堀部敬三, 林泰秀
    • Organizer
      第67回日本癌学会
    • Place of Presentation
      名古屋
    • Related Report
      2009 Final Research Report 2008 Annual Research Report
  • [Presentation] DNAマイクロアレイによる小児急性骨髄性白血病の診断2008

    • Author(s)
      城青衣, 高橋広夫, 月本一郎, 堀部敬三, 多和昭雄, 五十嵐隆, 林泰秀, 市川仁
    • Organizer
      第67回日本癌学会
    • Place of Presentation
      名古屋
    • Related Report
      2009 Final Research Report 2008 Annual Research Report
  • [Presentation] 高密度SNPアレイを用いた神経芽腫における網羅的ゲノム解析2008

    • Author(s)
      滝田順子, 加藤元博, 陳玉彦, 大平美紀, 真田昌, 菊地陽, 本村あい, 康勝好, 井田孔明, 五十嵐隆, 中川原章, 林泰秀, 小川誠司
    • Organizer
      第50回日本小児血液学会・第24回日本小児がん学会
    • Place of Presentation
      幕張
    • Related Report
      2009 Final Research Report 2008 Annual Research Report
  • [Presentation] 小児T細胞型急性リンパ性白血病の最新の話題-分子病態を中心に-2008

    • Author(s)
      林泰秀
    • Organizer
      第50回日本小児血液学会・第24回日本小児がん学会
    • Place of Presentation
      幕張
    • Related Report
      2009 Final Research Report 2008 Annual Research Report
  • [Presentation] ALL標準危険群に対するTCCSG治療戦略の変遷:TCCSG ALL L85-12、92-13、95-14、99-15研究2008

    • Author(s)
      康勝好, 小原明, 磯山恵一, 梶原道子, 小池和俊, 金澤崇, 嶋田博之, 田中竜平, 熊谷昌明, 木下明俊, 杉田完爾, 杉田憲一, 真部淳, 林泰秀, 前田美穂, 花田良二, 土田昌宏
    • Organizer
      第50回日本小児血液学会・第24回日本小児がん学会
    • Place of Presentation
      幕張
    • Related Report
      2009 Final Research Report
  • [Presentation] 東京小児がん研究グループ(TCCSG)急性リンパ性白血病(ALL)マーカー中央診断におけるT-ALLのマーカー解析2008

    • Author(s)
      恩田恵子, 清河信敬, 藤本純一郎, 齋藤正博, 大喜多肇, 梶原道子, 福島敬, 犬飼岳史, 牧本敦, 真部淳, 康勝好, 中川温子, 小原明, 林泰秀, 花田良二, 土田昌宏
    • Organizer
      第50回日本小児血液学会・第24回日本小児がん学会
    • Place of Presentation
      幕張
    • Related Report
      2009 Final Research Report
  • [Presentation] B precursor-ALLに対する中枢神経白血病予防治療の変遷と成績:TCCSG ALL L89-12、92-13、95-14、99-15研究2008

    • Author(s)
      小川千登世, 小原明, 真部淳, 菊地陽, 康勝好, 富澤大輔, 藤村純也, 井上裕靖, 角南勝介, 石井栄三郎, 塩原正明, 森鉄也, 高橋裕之, 林泰秀, 花田良二, 土田昌宏
    • Organizer
      第50回日本小児血液学会・第24回日本小児がん学会
    • Place of Presentation
      幕張
    • Related Report
      2009 Final Research Report
  • [Presentation] 小児急性リンパ性白血病に対する寛解導入療法・早期強化療法の安全性に関する検討:TCCSG L04-16研究2008

    • Author(s)
      小嶋靖子, 太田節雄, 牧本敦, 小原明, 福島啓太郎, 福島敬, 犬飼岳史, 秋山政晴, 子川和宏, 矢部普正, 康勝好, 清河信敬, 真部淳, 林泰秀, 花田良二, 土田昌宏
    • Organizer
      第50回日本小児血液学会・第24回日本小児がん学会
    • Place of Presentation
      幕張
    • Related Report
      2009 Final Research Report
  • [Presentation] DNAマイクロアイレによる小児急性骨髄性白血病の診断2008

    • Author(s)
      城青衣, 高橋広夫, 嶋田明, 月本一朗, 堀部敬三, 多和昭雄, 石井榮一, 五十嵐隆, 林泰秀, 市川仁
    • Organizer
      第50回日本小児血液学会・第24回日本小児がん学会
    • Place of Presentation
      幕張
    • Related Report
      2009 Final Research Report 2008 Annual Research Report
  • [Presentation] JPLSG AML05臨床試験における新WHO分類を用いた横断的中央診断2008

    • Author(s)
      木下明俊, 宮地勇人, 滝智彦, 高橋浩之, 林泰秀, 多和昭雄
    • Organizer
      第50回日本小児血液学会・第24回日本小児がん学会
    • Place of Presentation
      幕張
    • Related Report
      2009 Final Research Report 2008 Annual Research Report
  • [Presentation] 超高密度オリゴヌクレオチドアレイを用いた小児急性骨髄性白血病における網羅的ゲノム解析2008

    • Author(s)
      大木健太郎, 滝田順子, 加藤元博, 陳玉彦, 真部淳, 菊地陽, 五十嵐隆, 小川誠司, 林泰秀
    • Organizer
      第50回日本小児血液学会・第24回日本小児がん学会
    • Place of Presentation
      幕張
    • Related Report
      2009 Final Research Report 2008 Annual Research Report
  • [Presentation] 急性骨髄性白血病におけるWT1遺伝子変異の解析2008

    • Author(s)
      佐野弘純, 久保田知里, 朴明子, 山田佳之, 外松学, 林泰秀
    • Organizer
      第50回日本小児血液学会・第24回日本小児がん学会
    • Place of Presentation
      幕張
    • Related Report
      2009 Final Research Report 2008 Annual Research Report
  • [Presentation] 高密度SNPアレイを用いた横紋筋肉腫におけるMolecular allelo-karyotyping2008

    • Author(s)
      加藤元博, 滝田順子, 陳玉彦, 真田昌, 大木健太郎, 本村あい, 康勝好, 井田孔明, 菊地陽, 五十嵐隆, 林泰秀, 小川誠司
    • Organizer
      第50回日本小児血液学会・第24回日本小児がん学会
    • Place of Presentation
      幕張
    • Related Report
      2009 Final Research Report
  • [Presentation] MLL遺伝子再構成陽性白血病における網羅的ゲノム解析2008

    • Author(s)
      加藤元博, 滝田順子, 陳玉彦, 真田昌, 康勝好, 井田孔明, 本村あい, 菊地陽, 滝智彦, 五十嵐隆, 小川誠司, 林泰秀
    • Organizer
      第50回日本小児血液学会・第24回日本小児がん学会
    • Place of Presentation
      幕張
    • Related Report
      2009 Final Research Report 2008 Annual Research Report
  • [Presentation] ALK遺伝子の活性型変異は神経芽腫の発症に関与する2008

    • Author(s)
      陳玉彦, 滝田順子, 崔永林, 加藤元博, 大平美紀, 真田昌, 菊地陽, 五十嵐隆, 中川原章, 林泰秀, 間野博行, 小川誠司
    • Organizer
      第50回日本小児血液学会・第24回日本小児がん学会
    • Place of Presentation
      幕張
    • Related Report
      2009 Final Research Report 2008 Annual Research Report
  • [Presentation] 当科で治療を受けた小児がん患者の晩期障害についての検討2008

    • Author(s)
      外松学, 佐野弘純, 山田佳之, 朴明子, 林泰秀
    • Organizer
      第50回日本小児血液学会・第24回日本小児がん学会
    • Place of Presentation
      幕張
    • Related Report
      2009 Final Research Report
  • [Presentation] 脳静脈洞血栓症で発見されたJAK2V617F変異を伴った本態性血小板血症2008

    • Author(s)
      黒澤秀光, 奥谷真由子, 萩澤進, 佐藤雄也, 松下卓, 福島啓太郎, 杉田憲一, 朴明子, 林泰秀, 有阪治
    • Organizer
      第50回日本小児血液学会・第24回日本小児がん学会
    • Place of Presentation
      幕張
    • Related Report
      2009 Final Research Report
  • [Presentation] 小児AML with multilineage dysplasiaの女児例2008

    • Author(s)
      朴明子, 佐野弘純, 山田佳之, 外松学, 林泰秀
    • Organizer
      第50回日本小児血液学会・第24回日本小児がん学会
    • Place of Presentation
      幕張
    • Related Report
      2009 Final Research Report
  • [Presentation] 神経芽腫におけるreceptor tyrosine kinaseの発現、変異と臨床像2008

    • Author(s)
      佐野弘純, 若井公子, 朴明子, 山田佳之, 外松学, 林泰秀
    • Organizer
      第50回日本小児血液学会・第24回日本小児がん学会
    • Place of Presentation
      幕張
    • Related Report
      2009 Final Research Report
  • [Presentation] 生検後急速に増大した幼児期発症肝血管内皮腫の女児例2008

    • Author(s)
      朴明子、佐野弘純、山田佳之、外松学、黒岩実、鈴木則夫、畠山信逸、櫻井英幸、平戸純子、福田晃也、笠原群生, 中川温子, 林泰秀
    • Organizer
      第50回日本小児血液学会・第24回日本小児がん学会
    • Place of Presentation
      幕張
    • Related Report
      2009 Final Research Report
  • [Presentation] 小児T細胞型白血病におけるPTEN遺伝子の解析2008

    • Author(s)
      朴明子, 滝智彦, 佐野弘純, 山田佳之, 外松学, 林泰秀
    • Organizer
      第50回日本小児血液学会・第24回日本小児がん学会
    • Place of Presentation
      幕張
    • Related Report
      2009 Final Research Report 2008 Annual Research Report
  • [Presentation] 診断後早期の臓器障害併発のために臨床試験に参加できなかった重症ALL7症例の臨床像の検討2008

    • Author(s)
      外松学, 齋藤正博, 野口靖, 高橋浩之, 金子隆, 矢部みはる, 真部淳, 小原明, 花田良二, 土田昌宏
    • Organizer
      第50回日本小児血液学会・第24回日本小児がん学会
    • Place of Presentation
      幕張
    • Related Report
      2009 Final Research Report
  • [Presentation] FBW7 and NOTCH1 mutations in childhood T-cell acute lymphoblastic leukemia and T-cell non-Hodgkin's lymphoma ; a Japan association of childhood leukemia study group2008

    • Author(s)
      Park MJ, 他
    • Organizer
      第48回イギリス血液学会
    • Place of Presentation
      イギリス
    • Related Report
      2008 Annual Research Report
  • [Presentation] Moecular allelo-karyotyping of neuroblastoma using high-resolution single nucleotide polymorphism genomic microarrays2008

    • Author(s)
      Kato M, 他
    • Organizer
      ANR
    • Place of Presentation
      千葉
    • Related Report
      2008 Annual Research Report
  • [Presentation] Genome-wide analysis of epigenetic abnormalities in neuroblastoma using oligonucleotide tiling array2008

    • Author(s)
      Kato M, 他
    • Organizer
      ANR
    • Place of Presentation
      千葉
    • Related Report
      2008 Annual Research Report
  • [Presentation] High-resolution copy number analysis and identification of target genes in neuroblastoma using high-density SNP-genotyping microarrays2008

    • Author(s)
      Takita J, 他
    • Organizer
      ANR
    • Place of Presentation
      千葉
    • Related Report
      2008 Annual Research Report
  • [Presentation] Expression of KIT and PDGFR is associated with a good clinical outcome in neuroblastoma2008

    • Author(s)
      Sano H, 他
    • Organizer
      ANR
    • Place of Presentation
      千葉
    • Related Report
      2008 Annual Research Report
  • [Presentation] 小児ALLに対する化学療法早期の有効性と安全性の検討:TCCSG ALL L 04-16研究2008

    • Author(s)
      小原明, 他
    • Organizer
      第70回日本血液学会総会
    • Place of Presentation
      京都
    • Related Report
      2008 Annual Research Report
  • [Presentation] 小児AML with multilineage dysplasia の2例2008

    • Author(s)
      朴明子, 他
    • Organizer
      第70回日本血液学会総会
    • Place of Presentation
      京都
    • Related Report
      2008 Annual Research Report
  • [Presentation] 超高密度SNPアレイを用いたMLL再構成陽性小児白血病における molecular allelo-karyotyping2008

    • Author(s)
      滝田順子, 他
    • Organizer
      第70回日本血液学会総会
    • Place of Presentation
      京都
    • Related Report
      2008 Annual Research Report
  • [Presentation] 小児急性骨髄球性白血病における Molecular allelo-karyotyping2008

    • Author(s)
      大木健太郎, 他
    • Organizer
      第70回日本血液学会総会
    • Place of Presentation
      京都
    • Related Report
      2008 Annual Research Report
  • [Presentation] 高密度SNPマイクロアレイを用いた本邦の小児急性リンパ芽球性白血病の molecular karyotyping2008

    • Author(s)
      清河信敬, 他
    • Organizer
      第70回日本血液学会総会
    • Place of Presentation
      京都
    • Related Report
      2008 Annual Research Report
  • [Presentation] 高密度SNPアレイを用いた横紋筋肉腫における Molecular allelo-karyotyping2008

    • Author(s)
      加藤元博, 他
    • Organizer
      第50回日本小児血液学会・第24回日本小児がん学会
    • Place of Presentation
      幕張
    • Related Report
      2008 Annual Research Report
  • [Presentation] 小児AML with multilineage dysplasia の女児例2008

    • Author(s)
      朴明子, 他
    • Organizer
      第50回日本小児血液学会・第24回日本小児がん学会
    • Place of Presentation
      幕張
    • Related Report
      2008 Annual Research Report
  • [Presentation] 神経芽腫における receptor tyrosine kinase の発現、変異と臨床像2008

    • Author(s)
      佐野弘純, 他
    • Organizer
      第50回日本小児血液学会・第24回日本小児がん学会
    • Place of Presentation
      幕張
    • Related Report
      2008 Annual Research Report
  • [Presentation] T細胞型白血病におけるNOTCH1とP53遺伝子変異についての解析2007

    • Author(s)
      朴 明子、外松 学、林 泰秀, 他
    • Organizer
      第110回日本小児科学会学術集会
    • Place of Presentation
      京都
    • Related Report
      2007 Annual Research Report
  • [Presentation] 小児T-ALLとT-NHLにおけるNOTCH1遺伝子の解析と臨床的意義2007

    • Author(s)
      朴 明子、林 泰秀, 他
    • Organizer
      第4回JPLSG研究会
    • Place of Presentation
      名古屋
    • Related Report
      2007 Annual Research Report
  • [Presentation] 小児T細胞型白血病におけるNOTCH1細胞周期関連遺伝子の解析2007

    • Author(s)
      朴 明子、林 泰秀, 他
    • Organizer
      第66回日本癌学会学術総会
    • Place of Presentation
      横浜
    • Related Report
      2007 Annual Research Report
  • [Presentation] 小児T細胞型白血病におけるNOTCH1遺伝変異についての解析と臨床的意義2007

    • Author(s)
      朴 明子、林 泰秀, 他
    • Organizer
      第69回日本血液学会、第49回日本臨床血液学会
    • Place of Presentation
      横浜
    • Related Report
      2007 Annual Research Report
  • [Presentation] 小児造血器腫瘍におけるチロシンキナーゼの臨床的意義2007

    • Author(s)
      林 泰秀、嶋田 明、朴 明子
    • Organizer
      第45回癌治療学会総会
    • Place of Presentation
      京都
    • Related Report
      2007 Annual Research Report
  • [Presentation] CDC4 and NOTCH1 Mutations in Childhood T-Cell Acute Lymphoblasic Leukemia and T Cell Non-Hodgkin's Lymphoma;a Japan Association of Childhood Leukemia Study Group.2007

    • Author(s)
      Park MJ, Hayashi Y, et. al.
    • Organizer
      第49回アメリカ血液学会(ASH)
    • Place of Presentation
      アトランタ
    • Related Report
      2007 Annual Research Report
  • [Presentation] 小児T-ALLとT-NHLにおけるNOTCH1とCDC4遺伝子の解析と臨床的意義2007

    • Author(s)
      朴 明子、林 泰秀, 他
    • Organizer
      第49回日本小児血液学会、第23回日本小児がん学会学術集会
    • Place of Presentation
      仙台
    • Related Report
      2007 Annual Research Report
  • [Presentation] 小児骨髄性疾患におけるMolecular allelo-karyotyping2007

    • Author(s)
      加藤 元博、林 泰秀, 他
    • Organizer
      第4回JPLSG研究会
    • Place of Presentation
      名古屋
    • Related Report
      2007 Annual Research Report
  • [Presentation] 小児急性骨髄性白血病におけるWT1の高発現はFLT3遺伝子変異と相関する2007

    • Author(s)
      嶋田 明、林 泰秀, 他
    • Organizer
      第4回JPLSG研究会
    • Place of Presentation
      名古屋
    • Related Report
      2007 Annual Research Report
  • [Presentation] マイクロアレイ解析により明らかとなった単球系AMLの発症年齢依存的な遺伝子発現と予後2007

    • Author(s)
      城青 衣、林 泰秀, 他
    • Organizer
      第4回JPLSG研究会
    • Place of Presentation
      名古屋
    • Related Report
      2007 Annual Research Report
  • [Presentation] 同一の遺伝子が関与するキメラ遺伝子産物の多様性とその評価2007

    • Author(s)
      滝智 彦、林 泰秀, 他
    • Organizer
      日本人類遺伝学会第52回大会
    • Place of Presentation
      東京
    • Related Report
      2007 Annual Research Report
  • [Presentation] 高密度オリゴヌクレオチドアレイを用いた神経芽腫における網羅的エピゲノム解析2007

    • Author(s)
      加藤 元博、林 泰秀, 他
    • Organizer
      第66回日本癌学会学術総会
    • Place of Presentation
      横浜
    • Related Report
      2007 Annual Research Report
  • [Presentation] 神経芽腫における網羅的ゲノム解析と17q上の候補がん遺伝子であるNBA17遺伝子の同定2007

    • Author(s)
      滝田 順子、林 泰秀, 他
    • Organizer
      第66回日本癌学会学術総会
    • Place of Presentation
      横浜
    • Related Report
      2007 Annual Research Report
  • [Presentation] Hoxa9とRas-MAPキナーゼ系の協調作用がMLL融合蛋白による急性白血病の発症に重要である2007

    • Author(s)
      小埜 良一、林 泰秀, 他
    • Organizer
      第66回日本癌学会学術総会
    • Place of Presentation
      横浜
    • Related Report
      2007 Annual Research Report
  • [Presentation] バブルPCR法を応用した新しいキメラ転写産物同定法によるt(2;21)を有するT-ALLからのAML1-LAF4融合遺伝子の単離2007

    • Author(s)
      知念 良顕、林 泰秀, 他
    • Organizer
      第66回日本癌学会学術総会
    • Place of Presentation
      横浜
    • Related Report
      2007 Annual Research Report
  • [Presentation] 単球系およびMLL遺伝子再構成急性骨髄性白血病における発症年齢依存的な遺伝子発現2007

    • Author(s)
      城青 衣、林 泰秀, 他
    • Organizer
      第66回日本癌学会学術総会
    • Place of Presentation
      横浜
    • Related Report
      2007 Annual Research Report
  • [Presentation] 急性骨髄性白血病におけるWT1 mRNAの高発現はFLT3遺伝子変異と相関する2007

    • Author(s)
      嶋田 明、林 泰秀, 他
    • Organizer
      第69回日本血液学会、第49回日本臨床血液学会
    • Place of Presentation
      横浜
    • Related Report
      2007 Annual Research Report
  • [Presentation] MLL融合蛋白はRas-MAPキナーゼ系の活性化と相乗的に協調して急性白血病を発症する2007

    • Author(s)
      小埜 良一、林 泰秀, 他
    • Organizer
      第69回日本血液学会、第49回日本臨床血液学会
    • Place of Presentation
      横浜
    • Related Report
      2007 Annual Research Report
  • [Presentation] 高密度アレイを用いた乳児白血病の網羅的なゲノム・エビゲノム解析2007

    • Author(s)
      滝田 順子、林 泰秀, 他
    • Organizer
      第69回日本血液学会、第49回日本臨床血液学会
    • Place of Presentation
      横浜
    • Related Report
      2007 Annual Research Report
  • [Presentation] バブルPCR法を応用した新しいキメラ転写産物同定法によるt(2;21)を有するT-ALLからのAML1-LAF4の同定2007

    • Author(s)
      知念 良顕、林 泰秀, 他
    • Organizer
      第69回日本血液学会、第49回日本臨床血液学会
    • Place of Presentation
      横浜
    • Related Report
      2007 Annual Research Report
  • [Presentation] 切断点集中領域の外側に切断点を有するMLL再構成陽性白血病症例の解析2007

    • Author(s)
      滝智 彦、林 泰秀, 他
    • Organizer
      第69回日本血液学会、第49回日本臨床血液学会
    • Place of Presentation
      横浜
    • Related Report
      2007 Annual Research Report
  • [Presentation] 最新のマイクロアレイ技術を用いた若年性急性骨髄単球性白血病における網羅的ゲノム・メチル化解析2007

    • Author(s)
      陳 玉彦、林 泰秀, 他
    • Organizer
      第69回日本血液学会、第49回日本臨床血液学会
    • Place of Presentation
      横浜
    • Related Report
      2007 Annual Research Report
  • [Presentation] MLL-p300キメラ遺伝子を認めた二次性白血病の1例2007

    • Author(s)
      大西 宏明、林 泰秀, 他
    • Organizer
      第69回日本血液学会、第49回日本臨床血液学会
    • Place of Presentation
      横浜
    • Related Report
      2007 Annual Research Report
  • [Presentation] Cloning of AML1-LAF4 Fusion Gene in Childhood T-Cell Acute Lymphoblastic Leukemia with t(2;21)(q11;q22)by Bubble PCR Method for cDNA2007

    • Author(s)
      Chinen Y, Hayashi Y, et. al.
    • Organizer
      第49回アメリカ血液学会(ASH)
    • Place of Presentation
      アトランタ
    • Related Report
      2007 Annual Research Report
  • [Presentation] Age-Associated Difference in Gene Expression of Pediatric Myelo-Monocytic and MLL-Rearranged AML2007

    • Author(s)
      Jo A, Hayashi Y, et. al.
    • Organizer
      第49回アメリカ血液学会(ASH)
    • Place of Presentation
      アトランタ
    • Related Report
      2007 Annual Research Report
  • [Presentation] High-Resolution Analyses of Genetic and Epigenetic Aberrations in Infant Leukemia with MLL Rearrangement2007

    • Author(s)
      Takita J, Hayashi Y, et. al.
    • Organizer
      第49回アメリカ血液学会(ASH)
    • Place of Presentation
      アトランタ
    • Related Report
      2007 Annual Research Report
  • [Presentation] 1歳の小児急性リンパ性白血病の臨床像及び治療成績の検討:東京小児がん研究グループ(TCCSG)からの報告2007

    • Author(s)
      富澤 大輔、林 泰秀, 他
    • Organizer
      第49回日本小児血液学会、第23回日本小児がん学会学術集会
    • Place of Presentation
      仙台
    • Related Report
      2007 Annual Research Report
  • [Presentation] 急性リンパ性白血病の染色体・遺伝子異常と予後:TCCSG ALL L95-14・L99-15研究2007

    • Author(s)
      高橋 浩之、林 泰秀, 他
    • Organizer
      第49回日本小児血液学会、第23回日本小児がん学会学術集会
    • Place of Presentation
      仙台
    • Related Report
      2007 Annual Research Report
  • [Presentation] 東京小児がん研究グループALL治療第16次研究(TCCSG LO4-16/06-16)におけるマーカー中央診断2007

    • Author(s)
      清河 信敬、林 泰秀, 他
    • Organizer
      第49回日本小児血液学会、第23回日本小児がん学会学術集会
    • Place of Presentation
      仙台
    • Related Report
      2007 Annual Research Report
  • [Presentation] DNAマイクロアレイによるAML99登録130症例の綱羅的遺伝子発現解析2007

    • Author(s)
      城青 衣、林 泰秀, 他
    • Organizer
      第49回日本小児血液学会、第23回日本小児がん学会学術集会
    • Place of Presentation
      仙台
    • Related Report
      2007 Annual Research Report
  • [Presentation] 乳児白血病における網羅的エビゲノム解析2007

    • Author(s)
      加藤 元博、林 泰秀, 他
    • Organizer
      第49回日本小児血液学会、第23回日本小児がん学会学術集会
    • Place of Presentation
      仙台
    • Related Report
      2007 Annual Research Report
  • [Presentation] 急性骨髄性白血病の化学療法後のWT1mRNAの高発現はFLT3遺伝子変異および予後と相関する2007

    • Author(s)
      嶋田 明、林 泰秀, 他
    • Organizer
      第49回日本小児血液学会、第23回日本小児がん学会学術集会
    • Place of Presentation
      仙台
    • Related Report
      2007 Annual Research Report
  • [Presentation] 横紋筋肉腫における網羅的ゲノム解析2007

    • Author(s)
      滝田 順子、林 泰秀, 他
    • Organizer
      第49回日本小児血液学会、第23回日本小児がん学会学術集会
    • Place of Presentation
      仙台
    • Related Report
      2007 Annual Research Report
  • [Presentation] 若年性急性骨髄単球性白血病における網羅的ゲノム・メチル化解析2007

    • Author(s)
      陳 玉彦、林 泰秀, 他
    • Organizer
      第49回日本小児血液学会、第23回日本小児がん学会学術集会
    • Place of Presentation
      仙台
    • Related Report
      2007 Annual Research Report
  • [Presentation] 神経芽腫におけるDNAメチル化領域の網羅的解析2007

    • Author(s)
      加藤 元博、林 泰秀, 他
    • Organizer
      第49回日本小児血液学会、第23回日本小児がん学会学術集会
    • Place of Presentation
      仙台
    • Related Report
      2007 Annual Research Report
  • [Presentation] JAK2遺伝子が転座に関与したt(9;17)(p24;q23)をもつ急性リンパ性白血病(ALL)2007

    • Author(s)
      川村 眞智子、林 泰秀, 他
    • Organizer
      第49回日本小児血液学会、第23回日本小児がん学会学術集会
    • Place of Presentation
      仙台
    • Related Report
      2007 Annual Research Report

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Published: 2007-04-01   Modified: 2016-04-21  

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