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3D MRI Visualization of Appetite Center in Rat Hypothalamus

Research Project

Project/Area Number 19591447
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeSingle-year Grants
Section一般
Research Field Radiation science
Research InstitutionNational Center of Neurology and Psychiatry

Principal Investigator

OGINO Takashi  National Center of Neurology and Psychiatry, 神経研究所・診断研究部, 室長 (50185526)

Co-Investigator(Kenkyū-buntansha) MORITA Hironobu  岐阜大学, 大学院・医学系研究科, 教授 (80145044)
NAKAMURA Shun  東京農工大学, 大学院・共生科学技術研究院, 教授 (00134619)
Project Period (FY) 2007 – 2008
Project Status Completed (Fiscal Year 2008)
Budget Amount *help
¥4,550,000 (Direct Cost: ¥3,500,000、Indirect Cost: ¥1,050,000)
Fiscal Year 2008: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
Fiscal Year 2007: ¥2,860,000 (Direct Cost: ¥2,200,000、Indirect Cost: ¥660,000)
Keywords生物物理学 / 生理学 / 脳・神経 / 可視化 / MRI / 食欲中枢 / 視床下部 / 生理物理 / 生物物理
Research Abstract

Mn^<2+>造営MRI法により生きた動物個体(ラット、マウス等)を用いて食欲調節の液性伝達および神経性伝達による視床下部における中枢投射を50um-100umの空間分解能で3次元画像化する方法を開発し、摂食促進/抑制因子の視床下部における反応部位を無侵襲、非破壊的に3次元MRI画像化し、同定した。

Report

(3 results)
  • 2008 Annual Research Report   Final Research Report ( PDF )
  • 2007 Annual Research Report
  • Research Products

    (13 results)

All 2008 2007

All Journal Article (2 results) Presentation (11 results)

  • [Journal Article] Development of an animal model and a social behavior assessment scoring method for developmental disorders.2008

    • Author(s)
      Koshiba M, Ogino T, Aoki I, Kanno I, and Nakamura S.
    • Journal Title

      Annals of General Psychiatry 7(Suppl I)

    • Related Report
      2008 Final Research Report
  • [Journal Article] Development of an animal model and a social behavior assessment scoring method for developmental disorders2008

    • Author(s)
      Koshiba, Mamiko
    • Journal Title

      Annals of General Psychiatry 7(Suppl I)

    • Related Report
      2008 Annual Research Report
  • [Presentation] 生後発達期の個体間相互作用が中脳、後脳領域に与える影響2008

    • Author(s)
      白川由佳、深澤総一、石崎美由紀、岩渕奈穂子、荻野孝史、青木伊知男、中村俊、小柴満美子
    • Organizer
      第31回日本分子生物学会年会
    • Place of Presentation
      神戸
    • Year and Date
      2008-12-11
    • Related Report
      2008 Final Research Report
  • [Presentation] 同士間社会性環境に影響を受ける扁桃核領域の神経発達2008

    • Author(s)
      三村喬生、深澤総一、岩渕奈穂子、石崎美由紀、荻野孝史、青木伊知男、中村俊、小柴満美子
    • Organizer
      第31回日本分子生物学会年会
    • Place of Presentation
      神戸
    • Year and Date
      2008-12-11
    • Related Report
      2008 Final Research Report
  • [Presentation] 生後発達期の個体間相互作用が中脳・後脳領域に与える影響2008

    • Author(s)
      白川由佳
    • Organizer
      第31回日本分子生物学会年会
    • Place of Presentation
      神戸
    • Year and Date
      2008-12-11
    • Related Report
      2008 Annual Research Report
  • [Presentation] 同士間社会性環境に影響を受ける扁桃核領域の発達2008

    • Author(s)
      三村喬生
    • Organizer
      第31回日本分子生物学会年会
    • Place of Presentation
      神戸
    • Year and Date
      2008-12-11
    • Related Report
      2008 Annual Research Report
  • [Presentation] 拡散強調画像による幼齢ラット脳への揺さぶり障害評価法の確立2008

    • Author(s)
      若松永憲、今泉好偉、横井美佳、中舘和彦、杉原文徳、荻野孝史、瀬尾芳輝
    • Organizer
      第36回日本磁気共鳴医学会大会
    • Place of Presentation
      旭川
    • Year and Date
      2008-09-11
    • Related Report
      2008 Annual Research Report 2008 Final Research Report
  • [Presentation] 幼齢ラット脳海馬領域の拡散強調画像の解析2008

    • Author(s)
      若松 永憲
    • Organizer
      第85回日本生理学会大会
    • Place of Presentation
      東京
    • Year and Date
      2008-03-26
    • Related Report
      2007 Annual Research Report
  • [Presentation] A social eating party induced affiliation behavior of chick reared in socially deprived condition.2008

    • Author(s)
      Mamiko Koshiba, Takashi Ogino, Ichio Aoki, Iwao Kanno, and Shun Nakamura.
    • Organizer
      CINP Pacific-Asia Regional Meeting 2008
    • Place of Presentation
      Kuala Lumpur
    • Year and Date
      2008-03-05
    • Related Report
      2008 Final Research Report
  • [Presentation] Development of an animal model and social behavior assessment scoring method for developmental disorders.2007

    • Author(s)
      Koshiba M, Ogino T, Aoki I, Kanno I, and Nakamura S.
    • Organizer
      3rd International Congress on Brain and Behaviour
    • Place of Presentation
      Thessaloniki, Greece
    • Year and Date
      2007-11-28
    • Related Report
      2008 Final Research Report
  • [Presentation] 拡散強調画像による幼齢ラット脳の解析2007

    • Author(s)
      若松永憲、福井美佳、今泉好偉、杉原文徳、荻野孝史、瀬尾芳輝
    • Organizer
      第35回日本磁気共鳴医学会
    • Place of Presentation
      神戸
    • Year and Date
      2007-09-28
    • Related Report
      2008 Final Research Report
  • [Presentation] 社会性コミュニケーション行動に関与する脳領域の7T MRIによる解析2007

    • Author(s)
      小柴満美子、荻野孝史、青木伊知男、池平博夫、菅野巌、中村俊
    • Organizer
      第35回日本磁器共鳴医学会
    • Place of Presentation
      神戸
    • Year and Date
      2007-09-28
    • Related Report
      2008 Final Research Report
  • [Presentation] 拡散強調画像による幼齢ラット脳の解析2007

    • Author(s)
      若松 永憲
    • Organizer
      第35回日本磁気共鳴医学会大会
    • Place of Presentation
      神戸
    • Year and Date
      2007-09-28
    • Related Report
      2007 Annual Research Report

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Published: 2007-04-01   Modified: 2016-04-21  

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