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Development of Radiation-Therapy Planning Using FDG-PET/CT Fused Imaging

Research Project

Project/Area Number 19591461
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeSingle-year Grants
Section一般
Research Field Radiation science
Research InstitutionKumamoto University

Principal Investigator

MURAKAMI Ryuji  Kumamoto University, 医学部・附属病院, 准教授 (90295147)

Co-Investigator(Kenkyū-buntansha) 白石 慎哉  熊本大学, 大学院・医学薬学研究部, 助教 (50433008)
平井 俊範  熊本大学, 大学院・医学薬学研究部, 准教授 (40274724)
Co-Investigator(Renkei-kenkyūsha) SHIRAISHI Shinya  熊本大学, 大学院・医学薬学研究部, 助教 (50433008)
HIRAI Toshinori  熊本大学, 大学院・医学薬学研究部, 准教授 (40274724)
Project Period (FY) 2007 – 2008
Project Status Completed (Fiscal Year 2008)
Budget Amount *help
¥3,380,000 (Direct Cost: ¥2,600,000、Indirect Cost: ¥780,000)
Fiscal Year 2008: ¥780,000 (Direct Cost: ¥600,000、Indirect Cost: ¥180,000)
Fiscal Year 2007: ¥2,600,000 (Direct Cost: ¥2,000,000、Indirect Cost: ¥600,000)
Keywords放射線治療学 / 放射線治療計画 / ポジトロン断層撮像(PET) / がん / 放射線治療 / 画像診断 / 機能画像 / 画像解析 / PET / 癌 / 臨床 / 放射線 / 画像 / 解析・評価
Research Abstract

模擬病巣およびPET用放射性薬剤(FDG)を用いた基礎的研究において、描出能は病巣の大きさおよび周囲RIカウントの影響を受けた。臨床評価における小病巣の過小評価および周囲炎症による過大評価が基礎的に明らかとなり、腫瘍-非腫瘍境界の閾値は症例毎に定める必要性が示唆された。FDG-PETを臨床応用したリンパ節転移の診断では、小径のリンパ節における閾値は低値を要した。位置情報を加味した三次元的腫瘍体積評価に関して、通常の臨床情報にPET-CTを追加することによる観察者間での差異の軽減が明らかとなった。

Report

(3 results)
  • 2008 Annual Research Report   Final Research Report ( PDF )
  • 2007 Annual Research Report
  • Research Products

    (10 results)

All 2009 2008 2007

All Journal Article (7 results) (of which Peer Reviewed: 7 results) Presentation (3 results)

  • [Journal Article] Grading Astrocytic Tumors by Using Apparent Diffusion Coefficient Parameters : Superiority of a One-versus Two-Parameter Pilot Method2009

    • Author(s)
      Ryuji Murakami
    • Journal Title

      Radiology (印刷中)

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Impact of FDG-PET/CT Fused Imaging on Tumor Volume Assessment of Head-And-Neck Squamous Cell Carcinoma : Intermethod and Interobserver Variations2008

    • Author(s)
      Ryuji Murakami, Hideaki Uozumi, Toshinori Hirai, Ryuichi Nishimura, Shigehiko Katsuragawa, Shinya Shiraishi, Ryo Toya, Kuniyuki Tashiro, Kouichi Kawanaka, Natsuo Oya, Seiji Tomiguchi, Yasuyuki Yamashita
    • Journal Title

      Acta Radiologica 49

      Pages: 693-699

    • Related Report
      2008 Final Research Report
    • Peer Reviewed
  • [Journal Article] Magnetic resonance imaging of pilocytic astrocytomas : usefulness of the minimumapparent diffusion coefficient (ADC)value for differentiation from high-grade gliomas2008

    • Author(s)
      Ryuji Murakami
    • Journal Title

      Acta Radiologica 49

      Pages: 462-467

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Impact of FDG-PET/CT Fused Imaging on Tumor Volume Assessment of Head-And-Neck Squamous Cell Carcinoma : Intermethod and Interobserver Variations2008

    • Author(s)
      Ryuji Murakami
    • Journal Title

      Acta Radiologica 49

      Pages: 693-699

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Impact of FDG-PET/CT Fused Imaging on Tumor Volume Assessment of Head-And-Neck Squamous Cell Carcinoma: Intermethod and Interobserver Variations2008

    • Author(s)
      Ryuji Murakami
    • Journal Title

      Acta Radiologica (掲載確定) (印刷中)

    • Related Report
      2007 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Impact of FDG-PET/CT imaging on nodal staging for head-and-neck squamous cell2007

    • Author(s)
      Ryuji Murakami, Hideaki Uozumi, Toshinori Hirai, Ryuichi Nishimura, Shinya Shiraishi, Kazutoshi Ohta, Daizo Murakami, Seiji Tomiguchi, Natsuo Oya, Shigehiko Katsuragawa, Yasuyuki Yamashita
    • Journal Title

      International Journal of Radiation Oncology, Biology, Physics 68

      Pages: 377-382

    • Related Report
      2008 Final Research Report
    • Peer Reviewed
  • [Journal Article] Impact of FDG-PET/CT imaging on nodal staging for head-and-neck squamous cell carcinoma2007

    • Author(s)
      Ryuji Murakami
    • Journal Title

      International Journal of Radiation Oncology, Biology, Physics 68

      Pages: 377-382

    • Related Report
      2007 Annual Research Report
    • Peer Reviewed
  • [Presentation] 山下康行PET-CTを応用した放射線治療計画における輪郭描出に関する検討2008

    • Author(s)
      東家亮、村上龍次、大屋夏生、白石慎哉、田代城主、吉田守克、冨口静二
    • Organizer
      日本放射線腫瘍学会第21回学術大会
    • Place of Presentation
      札幌パークホテル
    • Related Report
      2008 Final Research Report
  • [Presentation] Cone-Beam CTを用いた放射線治療計画に関する臨床的検討2008

    • Author(s)
      村上龍次、中口裕二、丸山雅人、筧清孝、坂部大介、村山淳一、東家亮、斉藤哲雄、坂本隆吏、大屋夏生、荒木不次男
    • Organizer
      第67回日本医学放射線学会総会
    • Place of Presentation
      パシフィコ横浜
    • Related Report
      2008 Annual Research Report 2008 Final Research Report
  • [Presentation] Diffusion-Weighted MR Imaging of Gliomas: Role in Their Diagnosis and Treatment2007

    • Author(s)
      Ryuji Murakami
    • Organizer
      第93回北米放射線学会(RSNA 2007)
    • Place of Presentation
      シカゴ(米国)
    • Related Report
      2007 Annual Research Report

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Published: 2007-04-01   Modified: 2016-04-21  

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