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Imaging analysis in men with lower urinary tract symptoms using transrectal elastography

Research Project

Project/Area Number 19591868
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeSingle-year Grants
Section一般
Research Field Urology
Research InstitutionKyoto Prefectural University of Medicine

Principal Investigator

OKIHARA Koji  Kyoto Prefectural University of Medicine, 医学研究科, 講師 (80285270)

Co-Investigator(Kenkyū-buntansha) NAKAMURA Terukazu  京都府立医科大学, 医学研究科, 助教 (10381964)
UKIMURA Osamu  京都府立医科大学, 医学研究科, 講師 (70275220)
MIZUTANI Yoichi  京都府立医科大学, 医学研究科, 准教授 (10243031)
KAWAUCHI Akihiro  京都府立医科大学, 医学研究科, 准教授 (90240952)
MIKI Tsuneharu  京都府立医科大学, 医学研究科, 教授 (10243239)
Project Period (FY) 2007 – 2008
Project Status Completed (Fiscal Year 2008)
Budget Amount *help
¥4,550,000 (Direct Cost: ¥3,500,000、Indirect Cost: ¥1,050,000)
Fiscal Year 2008: ¥650,000 (Direct Cost: ¥500,000、Indirect Cost: ¥150,000)
Fiscal Year 2007: ¥3,900,000 (Direct Cost: ¥3,000,000、Indirect Cost: ¥900,000)
Keywordsウロダイナミクス / エラストグラフィー / 前立腺肥大症 / 経直腸的超音波断層法 / 下部尿路閉塞 / 泌尿器科学 / 組織弾性 / 下部尿路
Research Abstract

今回、前立腺尿道部の経時的な開口動態に組織学的な弾性変化をみる目的で、組織弾性イメージング機能を用いて、排尿初期から終了にいたるまでの、前立腺部尿道の弾性イメージ(ひずみ値)の対比を行った。正常症例の前立腺部尿道周囲のひずみ値(elastic grade)は、他の前立腺部の領域(辺縁域、移行域、中心域、前方繊維筋脂肪組織)と対比すると明らかに低値であった。前立腺腹側のひずみ値は、膀胱頚部からより末梢に至るまで、全般的に低値であることが観察された。前立腺肥大症のelastic gradeは、正常例と対比して、高値の部分の比率が増加し、前方繊維筋脂肪組織群に相当する部分は正常例と同様にひずみ値が低値を示していたが、腺腫部分のひずみ値はheterogenous patternを示さず、比較的層別化しており、尿道部から末梢側に移行するに従い、ひずみ値は高値を示した。以上より、排尿障害の原因の一因として、尿道部、腺腫部分のひずみ値の違いが関与していることが示唆された。

Report

(3 results)
  • 2008 Annual Research Report   Final Research Report ( PDF )
  • 2007 Annual Research Report
  • Research Products

    (13 results)

All 2008 2007

All Journal Article (9 results) (of which Peer Reviewed: 5 results) Presentation (4 results)

  • [Journal Article] Real-time virtual ultrasonographic radiofrequency ablation of renal cell carcinoma2008

    • Author(s)
      Ukimura O, Mitterberger M, Okihara K, Miki T, Pinggera GM, Neururer R, Peschel R, Aigner F, Gradl J, Barts Colleselli D, Strasser H, Pallwein L
    • Journal Title

      Frauscher FBJU 101

      Pages: 707-711

    • Related Report
      2008 Final Research Report
  • [Journal Article] Ten year trend in prostate cancer screening with high prostate specific antigen exposure rate in Japan2008

    • Author(s)
      Okihara K, Kitamura K, Okada K, Mikami K, Ukimura O, Miki T.
    • Journal Title

      Int Urol. 15

      Pages: 156-160

    • NAID

      10021276771

    • Related Report
      2008 Final Research Report
  • [Journal Article] Current trends in diagnostic and therapeutic principles for prostate cancer in Japan2008

    • Author(s)
      Okihara K, Shiraishi T, Ukimura O, Mizutani Y, Kawauchi A, Miki T.
    • Journal Title

      Int J Urol. 13

      Pages: 239-243

    • NAID

      10024142452

    • Related Report
      2008 Final Research Report
  • [Journal Article] Current trends in diagnostic and therapeutic principles for prostate cancer in Japan2008

    • Author(s)
      Okihara K, et al.
    • Journal Title

      Int J Oncol 13

      Pages: 239-243

    • NAID

      10024142452

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Intraoperative ultrasonography in an era of minimallyinvasive urology.2008

    • Author(s)
      Ukimura 0, Okihara K, et al.
    • Journal Title

      Int J Urol. 15

      Pages: 673-680

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Naftopidil versus tamsulosin hydrochloride for lower urinary tract symptoms associated with benign prostatic hyperplasla with special reference to the storage symptom : a prospective randomized control led study.2008

    • Author(s)
      Ukimura 0, Okihara K, et al.
    • Journal Title

      Int J Urol. 15

      Pages: 1049-1054

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Ten year trend in prostate cancer screening with high prostate-specific antigen exposure rate in Japan.2008

    • Author(s)
      Okihara K, et. al.
    • Journal Title

      International J. Urol. 15

      Pages: 156-60

    • NAID

      10021276771

    • Related Report
      2007 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Clinical efficacy of alternative antiandrogen therapy in japanese men with relapsed prostate cancer after first-line hormanal therapy2007

    • Author(s)
      Okihara K, Ukimura O, Kanemitsu N, Mizutani Y, Kawauchi A, Miki T
    • Journal Title

      Int J Urol. 14

      Pages: 128-132

    • Related Report
      2008 Final Research Report
  • [Journal Article] Clinical efficacy of alternative antiandrogen therapy in Japanese men with relapsed prostate cancer after first-line hormon al therapy.2007

    • Author(s)
      Okihara K, et. al.
    • Journal Title

      International J. Urol. 14

      Pages: 128-32

    • Related Report
      2007 Annual Research Report
    • Peer Reviewed
  • [Presentation] Real-time transrectal ultrasonography during miniraparotomy radical prostatectomy2008

    • Author(s)
      Okihara K, Ukimura O, Kanazawa M, Mizutani Y, Kawauchi A. Miki T.
    • Organizer
      26th World congress of Endourology & SWL.
    • Place of Presentation
      Shanghai China
    • Year and Date
      2008-12-02
    • Related Report
      2008 Final Research Report
  • [Presentation] Real-time transrectal ultrasonography during miniraparotomy radical prostatectomy.2008

    • Author(s)
      0kihara K, Ukimura 0, Kanazawa M, Mizutani Y, Kawauchi A, Miki T.
    • Organizer
      26th World congress of Endourology &ESWL
    • Place of Presentation
      Shanghai China
    • Year and Date
      2008-12-02
    • Related Report
      2008 Annual Research Report
  • [Presentation] Can real-time transrectal elastography in combination with power Doppler sonography enhance prostate cancer detection2007

    • Author(s)
      Okihara K, Kamoi K, Ochiai A, Ukimura O, Ushijima S, Mizutani Y, Kawauchi A, Miki T.
    • Organizer
      American Urological Association, Annual meeting
    • Place of Presentation
      Anaheim Ca USA.
    • Year and Date
      2007-05-23
    • Related Report
      2008 Final Research Report
  • [Presentation] Can real-time transrectal elastography in combination with power Doppler sonography enhance prostate cancer detection?2007

    • Author(s)
      Okihara K, et. al.
    • Organizer
      American Urological Association, Annual meeting
    • Place of Presentation
      米国 アナハイム
    • Related Report
      2007 Annual Research Report

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Published: 2007-04-01   Modified: 2016-04-21  

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