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The control characterization of voice pitch (F0) by auditory feedback and related brain activation of stutters and non-stutterers.

Research Project

Project/Area Number 19591999
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeSingle-year Grants
Section一般
Research Field Otorhinolaryngology
Research InstitutionResearch Institute, National Rehabilitation Center for Persons with Disabilities

Principal Investigator

MORI Koichi  Research Institute, National Rehabilitation Center for Persons with Disabilities, 感覚機能系障害研究部・視覚機能障害研究室, 研究室長 (60157857)

Co-Investigator(Kenkyū-buntansha) SAKAI Naomi  目白大学, 保健医療学部, 助教 (60415362)
MASUDA Sayako  慶応義塾大学, 社会学研究科, 助教 (90415365)
OKAZAKI Shuntaro  国立障害者リハビリテーションセンター(研究所), 流動研究員 (80455378)
Project Period (FY) 2007 – 2009
Project Status Completed (Fiscal Year 2009)
Budget Amount *help
¥4,550,000 (Direct Cost: ¥3,500,000、Indirect Cost: ¥1,050,000)
Fiscal Year 2009: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2008: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2007: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
Keywords耳鼻咽喉学 / 音声 / 吃音 / 聴覚フィードバック / コミュニケーション障害 / 脳 / 医療・福祉 / 脳・神経 / 制御工学 / リハビリテーション / 言語
Research Abstract

The information of fundamental frequency (F0) and articulation of voice is fed back in real time by audition to the speech center of the brain for correcting deviation from the motor command. In this study, a method for accurately describing the F0 control characteristics of the auditory feedback was developed, and the peak amplitude of the resulting impulse responses with the latency of approximately 150ms were compared between the groups of people who do and do not stutter. The response peak depended on the F0 for the control subjects of both sexes, while it did not increase with F0 for most of stuttering subjects. Functional MRI revealed the right middle temporal gyrus, right and left precentral gyri, left inferior frontal gyrus and right insula as related to the F0 feedback control.

Report

(4 results)
  • 2009 Annual Research Report   Final Research Report ( PDF )
  • 2008 Annual Research Report
  • 2007 Annual Research Report
  • Research Products

    (38 results)

All 2010 2009 2008 2007

All Journal Article (13 results) (of which Peer Reviewed: 6 results) Presentation (23 results) Book (2 results)

  • [Journal Article] Effects of delayed auditory feedback on the vocal time-reproduction.2010

    • Author(s)
      Okazaki, S., Mori, K., Cai, C.
    • Journal Title

      Acoustical Science and Technology. 31(in press.)

    • NAID

      130000727358

    • Related Report
      2009 Final Research Report
    • Peer Reviewed
  • [Journal Article] 吃音検査. 特集耳鼻咽喉科・頭頚部外科の検査マニュアル─方法・結果とその解釈2010

    • Author(s)
      森浩一
    • Journal Title

      耳鼻咽喉科・頭頚部外科 82(5増刊号)

      Pages: 289-295

    • Related Report
      2009 Final Research Report
  • [Journal Article] Delayed auditory feedback Interferes vocal time-reproduction2010

    • Author(s)
      岡崎俊太郎
    • Journal Title

      Acoustical Science and Technology 31(In press)

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] 吃音検査2010

    • Author(s)
      森浩一
    • Journal Title

      耳鼻咽喉科・頭頚部外科 82(5増刊)

      Pages: 289-295

    • Related Report
      2009 Annual Research Report
  • [Journal Article] 聴覚フィードバックによる発声基本周波数制御に聴覚的注意が及ぼす効果2010

    • Author(s)
      岡崎俊太郎
    • Journal Title

      聴覚研究会資料 40

      Pages: 207-212

    • NAID

      110008001028

    • Related Report
      2009 Annual Research Report
  • [Journal Article] Brain activation in adults who stutter under delayed auditory feedback: An fMRI study.2009

    • Author(s)
      Sakai N, Masuda S, Shimotomai T, Mori K.
    • Journal Title

      International Journal of Speech-Language Pathology. 11(1)

      Pages: 2-11

    • Related Report
      2009 Final Research Report
    • Peer Reviewed
  • [Journal Article] Brain activation in adults who stutter under delayed auditory feedback : An fMRI study2009

    • Author(s)
      Sakai N, Masuda S, Shimotomai T, Mori K
    • Journal Title

      International Journal of Speech-Language Pathology 11

      Pages: 2-11

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Journal Article] 脳機能研究から吃音治療を展望する.2008

    • Author(s)
      森浩一
    • Journal Title

      コミュニケーション障害学 25(2)

      Pages: 121-128

    • NAID

      10024374679

    • Related Report
      2009 Final Research Report
    • Peer Reviewed
  • [Journal Article] 脳機能研究から吃音治療を展望する2008

    • Author(s)
      森浩一
    • Journal Title

      コミュニケーション障害学 25

      Pages: 121-128

    • NAID

      10024374679

    • Related Report
      2008 Annual Research Report
  • [Journal Article] 聴性言語反応の発達と障害.2007

    • Author(s)
      森浩一
    • Journal Title

      臨床脳波 49(6)

      Pages: 351-355

    • Related Report
      2009 Final Research Report
  • [Journal Article] Neural correlates of audiory feedback control in human2007

    • Author(s)
      Toyomura, A., et. al.
    • Journal Title

      Neuroscience 146

      Pages: 499-503

    • Related Report
      2007 Annual Research Report
    • Peer Reviewed
  • [Journal Article] 近赤外分光法(NIRS)による脳反応側性化の解析2007

    • Author(s)
      森 浩一
    • Journal Title

      認知神経科学 9

      Pages: 30-37

    • NAID

      130004388075

    • Related Report
      2007 Annual Research Report
  • [Journal Article] 聴性言語反応の発達と障害2007

    • Author(s)
      森 浩一
    • Journal Title

      臨床脳波 49

      Pages: 351-355

    • Related Report
      2007 Annual Research Report
  • [Presentation] 聴覚フィードバックによる発声基本周波数制御に聴覚的注意が及ぼす効果.2010

    • Author(s)
      岡崎俊太郎, 森浩一, 蔡暢
    • Organizer
      聴覚研究会資料.
    • Year and Date
      2010-03-05
    • Related Report
      2009 Final Research Report
  • [Presentation] 運動前野を経由する発話の第三経路2010

    • Author(s)
      蔡暢
    • Organizer
      電子情報通信学会総合大会
    • Place of Presentation
      仙台
    • Related Report
      2009 Annual Research Report
  • [Presentation] 脳機能と吃音について2009

    • Author(s)
      森浩一
    • Organizer
      横浜市難聴・言語障害通級指導教室専門研修会
    • Place of Presentation
      横浜
    • Year and Date
      2009-11-25
    • Related Report
      2009 Annual Research Report
  • [Presentation] Activity of Broca's area related to word familiarity effects during articulation2009

    • Author(s)
      蔡暢
    • Organizer
      The 39th annual meeting of the Society for Neuroscience
    • Place of Presentation
      Chicago
    • Year and Date
      2009-10-17
    • Related Report
      2009 Annual Research Report
  • [Presentation] Effect of the fundamental frequency and vocal register on the voice pitch compensation.2009

    • Author(s)
      Okazaki S, Mori K, Cai C.
    • Organizer
      The Acoustical Society of America.
    • Place of Presentation
      San Antonio
    • Related Report
      2009 Final Research Report
  • [Presentation] 吃音者および非吃音者における平均発声ピッチと聴覚フィードバックを用いたピッチ制御.2009

    • Author(s)
      岡崎俊太郎, 森浩一
    • Organizer
      第54回日本音声言語医学会総会・学術集会
    • Place of Presentation
      福島
    • Related Report
      2009 Final Research Report
  • [Presentation] 聴覚フィードバックに対する発話の引き込み現象.2009

    • Author(s)
      岡崎俊太郎, 森浩一, 蔡暢, 鎌谷大樹.
    • Organizer
      日本音響学会2009年春季研究発表会
    • Place of Presentation
      東京
    • Related Report
      2009 Final Research Report
  • [Presentation] The neural basis subserving unconscious pitch control revealed by transformed auditory feedback: A magnetic resonance imaging study.2009

    • Author(s)
      Masuda S, Okazaki S, Sakai-Mizokami N, Kamatani D, Mori K, Nakajima Y.
    • Organizer
      The 38th Annual Meeting of the Society for Neuroscience in North America
    • Place of Presentation
      Washington D.C.
    • Related Report
      2009 Final Research Report
  • [Presentation] Effect of the fundamental frequency and vocal register on the voice pitch compensation2009

    • Author(s)
      Okazaki, Shuntaro
    • Organizer
      The 158th Meeting of Acoustical Society of America
    • Place of Presentation
      San Antonio
    • Related Report
      2009 Annual Research Report
  • [Presentation] Low familiarity words activate the Broca's area during articulation2009

    • Author(s)
      蔡暢
    • Organizer
      The 32nd Annual Meeting of the Japan Neuroscience Society
    • Place of Presentation
      Nagoya
    • Related Report
      2009 Annual Research Report
  • [Presentation] Stuttering treatment in daily life with the behind-the-ear device2009

    • Author(s)
      Sakai, Naomi
    • Organizer
      6th World Congress on Fluency Disorders
    • Place of Presentation
      Riode Janeiro
    • Related Report
      2009 Annual Research Report
  • [Presentation] The neural basis subserving unconscious pitch control revealed by transformed auditory feedback : A magnetic resonance imaging study2008

    • Author(s)
      Masuda S, Okazaki S, Sakai-Mizokami N, Kamatani D, Mori K, Nakajima Y
    • Organizer
      The 38th Annual Meeting of the Society for Neuroscience in North America
    • Place of Presentation
      Washington D.C., U.S.A.
    • Year and Date
      2008-11-19
    • Related Report
      2008 Annual Research Report
  • [Presentation] Noninvasive assessment of language lateralization with in vivo near infrared spectroscopy.2008

    • Author(s)
      Mori K.
    • Organizer
      The 50th Anniversary Symposium of the Eaton-Peabody Laboratory of Auditory Physiology
    • Place of Presentation
      Boston.
    • Year and Date
      2008-06-13
    • Related Report
      2009 Final Research Report
  • [Presentation] Brain activation in adults who stutter under delayed auditory feedback : An fMRI study2008

    • Author(s)
      Sakai N, Masuda S, Shimotomai T, Mori K
    • Organizer
      Oxford Dysfluency Conference 2008
    • Place of Presentation
      Oxford, U.K.
    • Year and Date
      2008-06-05
    • Related Report
      2008 Annual Research Report
  • [Presentation] Brain activation in adults who stutter during reading under delayed auditory feedback: a fMRI study.2008

    • Author(s)
      Sakai N, Masuda S, Shimotomai T, Mori K.
    • Organizer
      Oxford Dysfluency Conference
    • Place of Presentation
      Oxford.
    • Related Report
      2009 Final Research Report
  • [Presentation] 聴覚フィードバックによるピッチ調節機構に発声の基本周波数が及ぼす影響.2008

    • Author(s)
      岡崎俊太郎, 森浩一, 鎌谷大樹, 増田早哉子.
    • Organizer
      日本音響学会2008年春季研究発表会
    • Place of Presentation
      津田沼
    • Related Report
      2009 Final Research Report
  • [Presentation] 聴覚フィードバックによるピッチ調節機構に発声の基本周波数が及ぼす影響2008

    • Author(s)
      岡崎 俊太郎, 他
    • Organizer
      日本音響学会2008年春季研究発表会
    • Place of Presentation
      津田沼
    • Related Report
      2007 Annual Research Report
  • [Presentation] 吃音と聴覚フィードバック-そのメカニズムに関する基礎研究-2007

    • Author(s)
      岡崎俊太郎, 森浩一, 鎌谷大樹, 増田早哉子.
    • Organizer
      第4回吃音を語る会
    • Place of Presentation
      東京
    • Year and Date
      2007-08-26
    • Related Report
      2009 Final Research Report
  • [Presentation] 聴覚フィードバックを用いたピッチ調節特性の同定と定量的解析.2007

    • Author(s)
      岡崎俊太郎, 森浩一, 鎌谷大樹, 増田早哉子.
    • Organizer
      第52回音声言語医学会総会・学術講演会
    • Place of Presentation
      所沢
    • Related Report
      2009 Final Research Report
  • [Presentation] 遅延聴覚フィードバック(DAF)下におけるfMRI計測-吃音者と非吃音者を対象に-2007

    • Author(s)
      酒井 奈緒美, 他
    • Organizer
      第52回日本音声言語医学会総会・学術講演会
    • Place of Presentation
      所沢
    • Related Report
      2007 Annual Research Report
  • [Presentation] 聴覚フィードバックを用いた微小な音声ピッチ変動に対する脳反応2007

    • Author(s)
      増田 早哉子, 他
    • Organizer
      第52回日本音声言語医学会総会・学術講演会
    • Place of Presentation
      所沢
    • Related Report
      2007 Annual Research Report
  • [Presentation] 聴覚フィードバックを用いたピッチ調節特性の同定と定量的解析2007

    • Author(s)
      岡崎 俊太郎, 他
    • Organizer
      第52回日本音声言語医学会総会・学術講演会
    • Place of Presentation
      所沢
    • Related Report
      2007 Annual Research Report
  • [Presentation] The neural basis subserving pitch control revealed by the transformed auditory feedback:A magnetic resonance imaging study2007

    • Author(s)
      Masuda, S., et. al.
    • Organizer
      The 37th Annual Meeting of the Society for Neuroscience in North America
    • Place of Presentation
      San Diego
    • Related Report
      2007 Annual Research Report
  • [Book] 言語障害(山口徹, 北原光夫, 福井次矢(編), 今日の治療指針2008年版)2008

    • Author(s)
      森浩一
    • Total Pages
      1118
    • Publisher
      医学書院
    • Related Report
      2009 Final Research Report
  • [Book] 今日の治療指針2008年版("言語障害"の項目を執筆)2008

    • Author(s)
      森 浩一
    • Total Pages
      1118
    • Publisher
      医学書院
    • Related Report
      2007 Annual Research Report

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Published: 2007-04-01   Modified: 2016-04-21  

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