• Search Research Projects
  • Search Researchers
  • How to Use
  1. Back to previous page

Fundamental study on treatment of shock that makes microcirculation management target

Research Project

Project/Area Number 19592099
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeSingle-year Grants
Section一般
Research Field Emergency medicine
Research InstitutionTokyo Women's Medical University

Principal Investigator

TAKADA Katsumi  Tokyo Women's Medical University, 医学部, 准教授 (20075609)

Co-Investigator(Kenkyū-buntansha) KOMORI Makiko  東京女子医科大学, 医学部, 准教授 (60178332)
TOMIZAWA Yasuko  東京女子医科大学, 医学部, 助教 (00159047)
Project Period (FY) 2007 – 2008
Project Status Completed (Fiscal Year 2008)
Budget Amount *help
¥3,900,000 (Direct Cost: ¥3,000,000、Indirect Cost: ¥900,000)
Fiscal Year 2008: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
Fiscal Year 2007: ¥2,080,000 (Direct Cost: ¥1,600,000、Indirect Cost: ¥480,000)
Keywordsショック / 微小循環 / rabbit ear chamber / ウリナスタチン / 輸液 / 敗血症 / REC
Research Abstract

各種ショック時の末梢循環を兎耳窓法を用いて観察した。補助薬としてウリナスタチン(UTI)を使用し比較した。アナフィラキシー、敗血症性ショック時に細動脈径、血流速度、血流量は低下したが、UTI の投与で微小循環は保たれた。出血性ショックにおいて輸液蘇生を膠質液と晶質液で比較したところ、膠質液では微小循環が良好に保たれた。微小循環の観点から、アナフィラキシーおよび敗血症時の末梢循環不良の改善にUTI が有利であること、急性出血時に膠質液輸液が有効であることがわかった。

Report

(3 results)
  • 2008 Annual Research Report   Final Research Report ( PDF )
  • 2007 Annual Research Report
  • Research Products

    (29 results)

All 2009 2008 2007

All Journal Article (15 results) (of which Peer Reviewed: 15 results) Presentation (12 results) Book (2 results)

  • [Journal Article] Spinal anesthetic management for hydrodistension of the bladder in patients with interstitial cystitis2009

    • Author(s)
      Hirai E, Komori M, Nishiyama K(他3名)
    • Journal Title

      J Tokyo Wom Med Univ 79

      Pages: 37-40

    • NAID

      120002365818

    • Related Report
      2008 Final Research Report
    • Peer Reviewed
  • [Journal Article] An infant with severe respiratory failure who responded to biphasic cuirass ventilation2009

    • Author(s)
      Nishiyama K, Komori M, Sato T (他5名)
    • Journal Title

      J Anesth 23

      Pages: 166-167

    • Related Report
      2008 Final Research Report
    • Peer Reviewed
  • [Journal Article] Microcirculatory responses to acupuncture stimulation and phototherapy2009

    • Author(s)
      Komori M, Takada K, Tomizawa Y, (他4名)
    • Journal Title

      Anesth Analg 108

      Pages: 635-640

    • Related Report
      2008 Final Research Report
    • Peer Reviewed
  • [Journal Article] Microcirculatory responses to acupuncture stimulation and phototherapy2009

    • Author(s)
      Komori M, Takada K, Tomizawa Y, et al.
    • Journal Title

      Anesth Analg 108

      Pages: 635-640

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Journal Article] ペインクリニック領域の治療が微小循環に与える影響2008

    • Author(s)
      小森万希子
    • Journal Title

      慢性疼痛 27

      Pages: 23-27

    • Related Report
      2008 Annual Research Report 2008 Final Research Report
    • Peer Reviewed
  • [Journal Article] 低出力レーザーおよび直線偏光近赤外線直接照射の皮膚微小循環に対する効果2008

    • Author(s)
      小森万希子
    • Journal Title

      日レ歯誌 19

      Pages: 26-29

    • NAID

      130003925158

    • Related Report
      2008 Annual Research Report 2008 Final Research Report
    • Peer Reviewed
  • [Journal Article] 心移植後の子宮体癌手術に対する麻酔経験2008

    • Author(s)
      井出早苗、小森万希子、西山圭子(他5名)
    • Journal Title

      東女医大誌 78

      Pages: 316-318

    • NAID

      110007524665

    • Related Report
      2008 Final Research Report
    • Peer Reviewed
  • [Journal Article] Effects of treatment with oral prostaglandin E1 on lumbar spinal canal stenosis2007

    • Author(s)
      Komori M, Nishiyama K, Kondo I (他5名)
    • Journal Title

      Pain Clinic 19

      Pages: 37-39

    • Related Report
      2008 Final Research Report
    • Peer Reviewed
  • [Journal Article] A woman who required long-term mechanical ventilation to treat limbic encephalitis during pregnancy2007

    • Author(s)
      Nishiyama K, Komori M, Narushima M (他3名)
    • Journal Title

      Acta Anaesthesiol Scand 51

      Pages: 252-254

    • Related Report
      2008 Final Research Report
    • Peer Reviewed
  • [Journal Article] 軽量で開閉可能な家兎耳介観察窓の開発2007

    • Author(s)
      佐藤章、冨澤康子、小森万希子、高田勝美
    • Journal Title

      呼と循 55

      Pages: 359-362

    • Related Report
      2008 Final Research Report 2007 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Permissive range of hypercapnia for improved peripheral microcirculation and cardiac output in rabbits2007

    • Author(s)
      Komori M, Takada K, Tomizawa Y (他3名)
    • Journal Title

      Crit Care Med 35

      Pages: 2171-5

    • Related Report
      2008 Final Research Report
    • Peer Reviewed
  • [Journal Article] Bronchoscopic removal of mucus casts in a boy with plastic bronchitis2007

    • Author(s)
      Hashida F, Komori M, Nishiyama K (他4名)
    • Journal Title

      Acta Anaesthesiol Scand 51

      Pages: 1283-4

    • Related Report
      2008 Final Research Report
    • Peer Reviewed
  • [Journal Article] Cases of pneumothorax and severe subcutaneous emphysema during laparoscopic surgery2007

    • Author(s)
      Kusabiraki T, Komori M, Nishiyama K (他3名)
    • Journal Title

      J Tokyo Wom Med Univ 77

      Pages: 59-63

    • NAID

      110007525297

    • Related Report
      2008 Final Research Report
    • Peer Reviewed
  • [Journal Article] 上顎歯肉・頬粘膜癌術後に長期呼吸管理を要した1例2007

    • Author(s)
      土屋由里、西山圭子、小森万希子(他2名)、谷口由枝、尾崎眞
    • Journal Title

      日歯麻誌 35

      Pages: 224-228

    • NAID

      10019921144

    • Related Report
      2008 Final Research Report
    • Peer Reviewed
  • [Journal Article] Permissive range of hypercapnia for improved peripheral microcirculation and cardiac output in rabbits.2007

    • Author(s)
      Komori M, Takada K, Tomizawa Y, Nishiyama K, Kawamata M, Ozaki M
    • Journal Title

      Crit Care Med. 35

      Pages: 2171-5

    • Related Report
      2007 Annual Research Report
    • Peer Reviewed
  • [Presentation] 全身麻酔中に循環不全を呈した冠攣縮性狭心症例2009

    • Author(s)
      井上寛、岡田翼、小森万希子ほか
    • Organizer
      東京女子医科大学学会第339 回例会
    • Place of Presentation
      東京
    • Year and Date
      2009-02-28
    • Related Report
      2008 Final Research Report
  • [Presentation] Microcirculatory Responses to Acupuncture Stimulation and Phototherapy2008

    • Author(s)
      Komori M, Takada K, Tomizawa Y, et. al.
    • Organizer
      Annual Meeting American Society of Anesthesiologists
    • Place of Presentation
      San Francisco, CA
    • Year and Date
      2008-10-15
    • Related Report
      2008 Final Research Report
  • [Presentation] ショック時の微小循環2008

    • Author(s)
      小森万希子
    • Organizer
      第36回日本救急医学会総会・学術集会
    • Place of Presentation
      札幌
    • Year and Date
      2008-10-14
    • Related Report
      2008 Final Research Report
  • [Presentation] ウリナスタチン・エダラボンの併用療法が敗血症時の微小循環に与える影響2008

    • Author(s)
      小森万希子、高田勝美、西山圭子ほか
    • Organizer
      日本麻酔科学会第55回学術集会
    • Place of Presentation
      横浜
    • Year and Date
      2008-06-13
    • Related Report
      2008 Annual Research Report 2008 Final Research Report
  • [Presentation] ペインクリニック領域の治療が微小循環に与える影響【教育講演】2008

    • Author(s)
      小森万希子
    • Organizer
      第37回日本慢性疼痛学会
    • Place of Presentation
      宇都宮
    • Year and Date
      2008-02-23
    • Related Report
      2008 Final Research Report
  • [Presentation] 当院でのCRPSに対する硬膜外刺激電極留置の施行経験2008

    • Author(s)
      小高桂子、小森万希子
    • Organizer
      第37回日本慢性疼痛学会
    • Place of Presentation
      宇都宮
    • Year and Date
      2008-02-23
    • Related Report
      2008 Final Research Report
  • [Presentation] 心移植後の子宮体癌手術に対する麻酔経験2008

    • Author(s)
      井出早苗 、小森万希子、西山圭子, ほか
    • Organizer
      東京女子医科大学学会第337回例会
    • Place of Presentation
      東京
    • Year and Date
      2008-02-23
    • Related Report
      2008 Final Research Report
  • [Presentation] シンポジウム 疼痛緩和とレーザー治療 臨床編「レーザーを用いたペインクリニック」2007

    • Author(s)
      小森万希子
    • Organizer
      第19回日本レーザー歯学会総会・学術大会
    • Place of Presentation
      鶴見
    • Year and Date
      2007-11-23
    • Related Report
      2008 Final Research Report
  • [Presentation] ショック時の微小循環 : 輸液の影響2007

    • Author(s)
      小森万希子
    • Organizer
      日本臨床麻酔学会第27回大会, 日本臨床麻酔学会誌(27(6) : S172)
    • Place of Presentation
      東京,
    • Year and Date
      2007-10-26
    • Related Report
      2008 Final Research Report
  • [Presentation] Oral Treatment with Prostaglandin E1 Improves Symptoms of Lumber Spinal Canal Stenosis2007

    • Author(s)
      Komori M, Sone Y, Tomizawa Y, et. Al.
    • Organizer
      American Society of Anesthesiologists
    • Place of Presentation
      San Francisco, CA
    • Year and Date
      2007-10-13
    • Related Report
      2008 Final Research Report
  • [Presentation] 鍼、レーザー、および直線偏光近赤外線直接照射の皮膚微小循環動態に対する効果2007

    • Author(s)
      小森万希子、高田勝美、福内明子ほか
    • Organizer
      日本麻酔科学会第54回学術集会
    • Place of Presentation
      札幌
    • Year and Date
      2007-05-31
    • Related Report
      2008 Final Research Report
  • [Presentation] Microcirculatory Responses to Acupuncture Stimulation and Phototherapy2007

    • Author(s)
      Makiko Komori, Katsumi Takada, Yasuko Tomizawa, Miwako Kawamata, Makoto Ozaki
    • Organizer
      American Society of Anesthesiologists
    • Place of Presentation
      San Francisco, CA
    • Related Report
      2007 Annual Research Report
  • [Book] 血行動態および各種臓器の血流. 克誠堂出版、光畑裕正編集2008

    • Author(s)
      小森万希子
    • Publisher
      For Professional Anesthesiologists アナフィラキシーショック、臨床編 ; アナフィラキシー時の末梢循環
    • Related Report
      2008 Final Research Report
  • [Book] For Professional Anesthesiologistsアナフィラキシーショック. 臨床編 : アナフィラキシー時の末梢循環、血行動態および各種臓器の血流, 光畑裕正編集2008

    • Author(s)
      小森万希子
    • Publisher
      克誠堂出版
    • Related Report
      2008 Annual Research Report

URL: 

Published: 2007-04-01   Modified: 2016-04-21  

Information User Guide FAQ News Terms of Use Attribution of KAKENHI

Powered by NII kakenhi