A study of pulpal responses to laser irradiation
Project/Area Number |
19592197
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Research Category |
Grant-in-Aid for Scientific Research (C)
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Allocation Type | Single-year Grants |
Section | 一般 |
Research Field |
Conservative dentistry
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Research Institution | Niigata University |
Principal Investigator |
YOSHIBA Nagako Niigata University, 医歯学総合病院, 講師 (10323974)
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Co-Investigator(Kenkyū-buntansha) |
YOSHIBA Kunihiko 新潟大学, 医歯学系, 准教授 (30220718)
TAKENAKA Shohji 新潟大学, 医歯学系, 助教 (50313549)
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Project Period (FY) |
2007 – 2009
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Project Status |
Completed (Fiscal Year 2009)
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Budget Amount *help |
¥4,550,000 (Direct Cost: ¥3,500,000、Indirect Cost: ¥1,050,000)
Fiscal Year 2009: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000)
Fiscal Year 2008: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Fiscal Year 2007: ¥2,600,000 (Direct Cost: ¥2,000,000、Indirect Cost: ¥600,000)
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Keywords | 半導体レーザー / Er:YAGレーザー / 象牙質・歯髄複合体 / 温度 / 細胞分化 / う蝕 / 修復 |
Research Abstract |
本研究の目的は、レーザーを応用したより快適でより生物学的なう蝕治療法の確立のための基礎的データーを得ることである。免疫組織学的、さらに遺伝子解析の方法を用いて、レーザー照射の象牙質・歯髄複合体への影響を調べた結果、半導体レーザー照射では、0.5Wと1.5Wの出力の差で治癒機転が大きく異なり、一方Er:YAGレーザーによる窩洞形成では、歯髄の損傷は軽度であり、従来の切削器具と同様な治癒過程を経ることが明らかとなった。
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Report
(4 results)
Research Products
(51 results)
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[Journal Article] Alveolar bone regeneration of subcutaneously transplanted rat molar2008
Author(s)
Hosoya A, Ninomiya T, Hiraga T, Zhao C, Yoshiba K, Yoshiba N, Takahashi M, Okabe T, Wakitani S, Yamada H, Kasahara E, Ozawa H, Nakamura H
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Journal Title
Related Report
Peer Reviewed
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[Journal Article] Immunohistochemical study of hard tissue formation in the rat pulp cavity after tooth replantation2007
Author(s)
Zhao C, Hosoya A, Kurita H, Hu T, Hiraga T, Ninomiya T, Yoshiba K, Yoshiba N, Takahashi M, Kurashina K, Ozawa H, Nakamura H
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Journal Title
Archives of Oral Biology 52
Pages: 945-953
Related Report
Peer Reviewed
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[Journal Article] Hard tissue formation in subcutaneously transplanted rat dental pulp2007
Author(s)
Hosoya A, Nakamura H, Ninomiya T, Hoshi K, Yoshiba K, Yoshiba N, Takahashi M, Okabe T, Sahara N, Yamada H, Kasahara E, Ozawa H
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Journal Title
Journal of Dental Research 86
Pages: 469-474
Related Report
Peer Reviewed
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[Journal Article] Immunohistochemical localization of alpha-Smooth muscle actin during rat molar tooth development2006
Author(s)
Hosoya A, Nakamura H, Ninomiya T, Yoshiba K, Yoshiba N, Nakaya H, Wakitani S, Yamada H, Kasahara E, Ozawa H
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Journal Title
Journal of Histochemistry, Cytochemistry 54
Pages: 1371-1378
Related Report
Peer Reviewed
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[Journal Article] Differential regulation of TIMP-1,-2, and-3 mRNA and protein expressions during mouse incisor development2006
Author(s)
Yoshiba N, Yoshiba K, Stoetzel C, Perrin-Schmitt F, Cam Y, Ruch JV, Hosoya A, Ozawa H, Lesot H
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Journal Title
Cell and Tissue Research 324
Pages: 97-104
Related Report
Peer Reviewed
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[Presentation] 再植歯の歯髄腔内における骨様組織形成2008
Author(s)
細矢明宏, Zhao Chen, 吉羽邦彦, 吉羽永子, 山田博仁, 笠原悦男, 小澤英浩, 中村浩彰
Organizer
日本歯科保存学会2008年度春季学術大会(第128回)
Place of Presentation
新潟
Year and Date
2008-06-05
Related Report
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