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Newly Strategy by Anti-angiogenic Gene Therapy using Decoy System

Research Project

Project/Area Number 19592342
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeSingle-year Grants
Section一般
Research Field Surgical dentistry
Research InstitutionKyushu University

Principal Investigator

KURAHARA Shin-ichi  Kyushu University, 大学院・歯学研究院, 助教 (20304818)

Co-Investigator(Kenkyū-buntansha) 石橋 浩晃  島根大学, 医学部, 准教授 (90254630)
鬼丸 満穂  九州大学, 医学研究院, 助教 (00380626)
竹之下 康治  九州大学, 歯学研究院, 准教授 (50117157)
Project Period (FY) 2007 – 2009
Project Status Completed (Fiscal Year 2009)
Budget Amount *help
¥4,420,000 (Direct Cost: ¥3,400,000、Indirect Cost: ¥1,020,000)
Fiscal Year 2009: ¥780,000 (Direct Cost: ¥600,000、Indirect Cost: ¥180,000)
Fiscal Year 2008: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
Fiscal Year 2007: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
Keywords口腔癌 / 血管新生 / 遺伝子治療 / 地管新生 / 分子標的治療
Research Abstract

Newly Strategy by Anti-angiogenic Gene Therapy using Decoy System

Report

(4 results)
  • 2009 Annual Research Report   Final Research Report ( PDF )
  • 2008 Annual Research Report
  • 2007 Annual Research Report
  • Research Products

    (18 results)

All 2009 2008 2007 Other

All Journal Article (15 results) (of which Peer Reviewed: 6 results) Presentation (1 results) Remarks (2 results)

  • [Journal Article] Autocrine loop between vascular endothelial growth factor(VEGF)-C and VEGF Receptor-3 positively regulates tumor-associated lymphangiogenesis in oral squamoid cancer cells.2009

    • Author(s)
      Matsuura M, Onimaru M, Yonemitsu Y, Suzuki H, Nakano T, Ishibashi H, Shirasuna K, Sueishi K.
    • Journal Title

      Am J Pathology 175(4)

      Pages: 1709-21

    • Related Report
      2009 Final Research Report
  • [Journal Article] Management of tongue squamous cell carcinoma in expectant patients: Report of two Cases.2009

    • Author(s)
      Kondo S, Ishibashi H, Nariai Y, Kato T, Enomoto Y, Karino M, Yoshino A, Sekine J
    • Journal Title

      Asian J Oral Maxillofac Surg 21(2)

      Pages: 142-148

    • Related Report
      2009 Final Research Report
  • [Journal Article] 1歳児の下顎骨に生じた小円形細胞腫瘍の1例2009

    • Author(s)
      蔵原慎一, 鬼丸満穂, 中村誠司, 石橋浩晃, 白砂兼光
    • Journal Title

      日本口腔外科学会雑誌 55(6)

      Pages: 305-309

    • NAID

      10027090653

    • Related Report
      2009 Final Research Report
  • [Journal Article] 非接触型三次元計測装置を用いた下顎後方移動術による顔面軟組織の三次元的形状変化の解析2009

    • Author(s)
      角町鎮男, 蔵原慎一, 佐々木匡理, 他6名
    • Journal Title

      日本口腔科学会雑誌 58(1)

      Pages: 11-18

    • Related Report
      2009 Final Research Report
  • [Journal Article] Feasible technique for the prediction of lymph node involvement in squamous cell carcinoma of the tongue by nuclear morphometric analysis.2009

    • Author(s)
      Karino M, Ishibashi H, Fujihara S, Watanabe M, Ichiba Y. Nariai Y Kondo S, Sekine J
    • Journal Title

      International Journal of Oral & Maxillofacial Surgery, proceedings of the 19th International Conference on Oral and Maxillofacial Surgery 38(5)

      Pages: 426-426

    • Related Report
      2009 Final Research Report
  • [Journal Article] Feasible technique for the prediction of lymph node involvement in squamous cell carcinoma of the tongue by nuclear morphometric analysis.2009

    • Author(s)
      Karino M, Ishibashi H, Fujiwara S, Watanabe M, Ichiba Y, Watanabe M, Ichiba Y, Nariai Y, Kondo S, Sekine J
    • Journal Title

      The International College of Surgeons, The 55th Annual Congress of the Japan Section, Proceedings 36

    • Related Report
      2009 Final Research Report
  • [Journal Article] Feasibility of implant supported fixed prostheses in oral tumor patients2009

    • Author(s)
      Nariai Y, Kondo S, Ishibashi H, Tsunematsu K, Asahina I, Sano K, Sekine J
    • Journal Title

      68th Annual Meeting of the Japanese Cancer Association, Proceedings 351

    • Related Report
      2009 Final Research Report
  • [Journal Article] Autocrine loop between vascular endothelial growth factor(VEGF)-C and VEGF Receptor-3 positively regulates tumor-associated lymphangiogenesis in oral squamoid cancer cells2009

    • Author(s)
      Matsuura M, Ishibashi H, et.al.
    • Journal Title

      Am J Pathology 175(4)

      Pages: 1709-1721

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Management of tongue squamous cell carcinoma in expectant patients : Report of two Cases2009

    • Author(s)
      Kondo S, Ishibashi H, et al.
    • Journal Title

      Asian J Oral Maxillofac Surg 21(2)

      Pages: 142-148

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Study on feasibility of cervical lymph node metastases in squamous cell carcinoma of the tongue evaluated by morphometric analyses.2008

    • Author(s)
      Karino M, Ishibashi H, Nariai Y, Kondo S, Sekine J
    • Journal Title

      PROCEEDINGS 12th International Congress on Oral Cancer in conjunction with 24th International College for Maxillo-Facial-Surgery

      Pages: 89-90

    • Related Report
      2009 Final Research Report
  • [Journal Article] Symposium 1: Surgical conference Case 1; A case of huge ameloblastoma manifested in the mandible2008

    • Author(s)
      Nariai Y, Nakamura M, Maruyama R, Ishibashi H, Sekine J
    • Journal Title

      Oral Medicine & Pathology 13(1)

      Pages: 29-29

    • Related Report
      2009 Final Research Report
  • [Journal Article] Inhibition of nuclear translocation of apoptosis-inducing factor is essential mechamnism of the neu2008

    • Author(s)
      Murakami Y, Ikeda Y, Onimaru M, e
    • Journal Title

      Am J Pathol 173(5)

      Pages: 1326-38

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Statins restore ischemic limb blood flow in diabetic microangiopathy via eNOS/NO upregulation b〓2008

    • Author(s)
      Fujii T, Onimaru M, et al
    • Journal Title

      Am J Physiol Heart Circ Physiol 294(6)

      Pages: 2785-91

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Journal Article] VEGF function for upregulation of endogenous PIGF expression during FGF-2-mediated therapeu2008

    • Author(s)
      Fujii T, Yonemitsu Y, Onimaru M et
    • Journal Title

      Atheroscrelosis Feb(5)(E Pub)

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Journal Article] VEGF function for upregulation of endogenous PIGF expression during FGF-2-mediated therapeutic angiogenesis2008

    • Author(s)
      Fujii T, Yonemitsu Y, Onimaru M, ら
    • Journal Title

      Atherosclerosis Feb5(Epub ahead of print)

    • Related Report
      2007 Annual Research Report
    • Peer Reviewed
  • [Presentation] 口腔癌の低酸素に依存する血管新生抑制療法の研究2007

    • Author(s)
      中川久子, 石橋浩晃
    • Organizer
      第52回日本口腔外科学会総会
    • Place of Presentation
      神戸
    • Related Report
      2009 Final Research Report
  • [Remarks] ホームページ

    • URL

      http://www.hosp.kyushu-u.ac.jp/shinryo/dent/08/index.html

    • Related Report
      2009 Final Research Report
  • [Remarks]

    • URL

      http://www.med.shimane-u.ac.jp/oral/index.html

    • Related Report
      2009 Final Research Report

URL: 

Published: 2007-04-01   Modified: 2016-04-21  

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