| Project/Area Number |
19592399
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Periodontal dentistry
|
|---|
| Research Institution | Hyogo College of Medicine |
|---|
Principal Investigator |
NAKASHO Keiji Hyogo College of Medicine, 医学部, 准教授 (00217712)
|
|---|
| Co-Investigator(Kenkyū-buntansha) |
OHYAMA Hideki 兵庫医科大学, 医学部, 講師 (90280685)
TERADA Nobuyuki 兵庫医科大学, 医学部, 教授 (50150339)
YAMADA Naoko 兵庫医科大学, 医学部, 講師 (10319858)
YAMANEGI Koji 兵庫医科大学, 医学部, 助教 (00434944)
NAKAMURA Hideji 兵庫医科大学, 医学部, 非常勤講師 (20237423)
URADE Masahiro 兵庫医科大学, 医学部, 教授 (70104883)
|
|---|
| Project Period (FY) |
2007 – 2009
|
| Project Status |
Completed (Fiscal Year 2009)
|
| Budget Amount *help |
¥4,420,000 (Direct Cost: ¥3,400,000、Indirect Cost: ¥1,020,000)
Fiscal Year 2009: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2008: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2007: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
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|---|
| Keywords | 歯周免疫機能学 / 脂肪性肝炎 / 歯周炎 / 肝機能マーカー / 血清IgG抗体価 |
|---|
| Research Abstract |
In the study to assess clinical parameters of periodontal diseases in patients with non-alcoholic steatohepatitis (NASH) and fatty liver diseases (FLD), we found that the patients with NASH showed the tendency to be more severe in periodontal condition as compared with the patients with FLD. The serum IgG titers against periodontopathic bacteria were also higher in the patients with NASH than the patients with FLD. These results might exhibit the possible effects of periodontal diseases on the pathogenesis of steatohepatitis.
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