Development of new analgesics and therapy for intractable pain
| Project/Area Number |
19603011
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Pain science
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| Research Institution | Tohoku Pharmaceutical University |
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Principal Investigator |
SAKURADA Shinobu Tohoku Pharmaceutical University, 薬学部, 教授 (30075816)
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| Co-Investigator(Kenkyū-buntansha) |
MIZOGUCHI Hirokazu 東北薬科大学, 薬学部, 准教授 (30360069)
WATANABE Chizuko 東北薬科大学, 薬学部, 助教 (90296020)
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| Project Period (FY) |
2007 – 2009
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| Project Status |
Completed (Fiscal Year 2009)
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| Budget Amount *help |
¥4,420,000 (Direct Cost: ¥3,400,000、Indirect Cost: ¥1,020,000)
Fiscal Year 2009: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2008: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2007: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
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| Keywords | 難治性疼痛 / 鎮痛薬 / オピオイド / 内因性ペプチド / ジーンセラピー |
|---|
| Research Abstract |
We investigated the mechanism for the reduced effectiveness of morphine in neuropathic pain stage in this project. With the mechanism investigated, we tried to develop the gene therapy for neuropathic pain. In addition, we also developed the new analgesic amidino-TAPA, which is extremely effective against neuropathic pain.
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Report
(4 results)
Research Products
(77 results)
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[Journal Article]2009
Author(s)
溝口広一
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Journal Title
生体の科学60((財)金原一郎記念医学医療振興財団/医学書院)
Pages: 448-449
Related Report
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[Journal Article]2009
Author(s)
Giacinto Bagetta
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Journal Title
In Memory of Vittorio Erspamer(EXORMA)
Pages: 101-113
Related Report
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