• Search Research Projects
  • Search Researchers
  • How to Use
  1. Back to previous page

Development of PET Imaging through Rapid Azaelectrocyclization and Oligosaccharide-Engineered Functional Macromolecules

Research Project

Project/Area Number 19681024
Research Category

Grant-in-Aid for Young Scientists (A)

Allocation TypeSingle-year Grants
Research Field Living organism molecular science
Research InstitutionOsaka University

Principal Investigator

TANAKA Katsunori  Osaka University, 大学院・理学研究科, 助教 (00403098)

Project Period (FY) 2007 – 2010
Project Status Completed (Fiscal Year 2010)
Budget Amount *help
¥26,130,000 (Direct Cost: ¥20,100,000、Indirect Cost: ¥6,030,000)
Fiscal Year 2010: ¥4,940,000 (Direct Cost: ¥3,800,000、Indirect Cost: ¥1,140,000)
Fiscal Year 2009: ¥4,940,000 (Direct Cost: ¥3,800,000、Indirect Cost: ¥1,140,000)
Fiscal Year 2008: ¥3,250,000 (Direct Cost: ¥2,500,000、Indirect Cost: ¥750,000)
Fiscal Year 2007: ¥13,000,000 (Direct Cost: ¥10,000,000、Indirect Cost: ¥3,000,000)
Keywordsアザ電子環状反応 / PET / 標識化 / イメージング / 糖鎖 / N-結合型糖タンパク質糖鎖 / 糖鎖クラスター / ポリリジン型デンドリマー / 自己活性化型Huisgen環化反応 / [^<68>Ga]-DOTA / 蛍光 / N-結合型タンパク質糖鎖 / 自己活性化型Huisen環化反応 / リジン残基 / PET(Positron Emission Tomography) / MRI(Manetic Resonance Imaing) / DOTA
Research Abstract

Efficient labeling of peptides, proteins, and antibodies were developed based on the rapid azaelectrocyclization, and the method was applied to the PET and the noninvasive fluorescence imaging. General solid-supported synthesis of N-glycans was established and their dendrimer-type clusters, mimicking the "glycan multivalency effects" in vivo, were efficiently prepared by his own "self-activating" Huisgen 1,3-dipolar cycloaddition. Modification of the proteins and/or the living cell surfaces by N-glycans were also established by rapid azaelectrocyclization. PET and noninvasive fluorescence imaging successfully visualized the trafficking of N-glycoclusters and N-glycan-engineered living cells to the specific organs and/or tumors implanted in living animals.

Report

(6 results)
  • 2010 Annual Research Report   Final Research Report ( PDF )
  • 2009 Annual Research Report   Self-evaluation Report ( PDF )
  • 2008 Annual Research Report
  • 2007 Annual Research Report
  • Research Products

    (246 results)

All 2011 2010 2009 2008 2007 Other

All Journal Article (31 results) (of which Peer Reviewed: 31 results) Presentation (175 results) Book (14 results) Remarks (22 results) Patent(Industrial Property Rights) (4 results) (of which Overseas: 1 results)

  • [Journal Article] Positron Emission Tomography (PET) and Fluorescence Imaging of Dendrimer-type N-Glycan Clusters : Remarkable Structural Dependency of Oligosaccharides on In Vivo Dynamics2010

    • Author(s)
      K.Tanaka, E.R.O.Siwu, K.Minami, K.Hasegawa, S.Nozaki, Y.Kanayama, K.Koyama, C.W.Chen, J.C.Paulson, Y.Watanabe, K.Fukase
    • Journal Title

      Angew.Chem.Int.Ed. 49

      Pages: 8195-8200

    • Related Report
      2010 Final Research Report
    • Peer Reviewed
  • [Journal Article] A Combined 6π-Azaelectrocyclization/Staudinger Approach to Protein&Cell Engineering : Non-Invasive Tumor Targeting by N-Glycan-Engineered Lymphocytes2010

    • Author(s)
      K.Tanaka, K.Minami, T.Tahara, E.R.O.Siwu, K.Koyama, S.Nozaki, H.Onoe, Y.Watanabe, K.Fukase
    • Journal Title

      J.Carbohydr.Chem. 29

      Pages: 118-132

    • Related Report
      2010 Final Research Report
    • Peer Reviewed
  • [Journal Article] Electrocyclization-Based Labeling Allows Efficient In Vivo Imaging of Cellular Trafficking2010

    • Author(s)
      K.Tanaka, K.Minami, T.Tahara, Y.Fujii, E.R.O.Siwu, S.Nozaki, H.Onoe, S.Yokoi, K.Koyama, Y.Watanabe, K.Fukase
    • Journal Title

      ChemMedChem 5

      Pages: 841-845

    • Related Report
      2010 Final Research Report
    • Peer Reviewed
  • [Journal Article] Self and Non-self Recognition with Bacterial and Animal Glycans, Surveys by Synthetic Chemistry2010

    • Author(s)
      Fujimoto, Y., Tanaka, K., et al.
    • Journal Title

      Method in Enzymolog

      Volume: 478 Pages: 323-324

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Non-Invasive Imaging of Dendrimer-type N-Glycan Clusters : Remarkable In Vivo Dynamics Dependence on Oligosacc haride Structure2010

    • Author(s)
      Tanaka, K., et al.
    • Journal Title

      Angew.Chem.Int.Ed.

      Volume: 49 Pages: 8195-8200

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Probe Design & Synthesis of Galβ(1-3)[NeuAcα(2-6)]GlcNAcβ(1-2)Man Motif of N-Glycan.2010

    • Author(s)
      Bao, G.-m., Tanaka, K., et al.
    • Journal Title

      Bioorg.Med.Chem.

      Volume: 18 Pages: 3760-3766

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] New strategy in synthetic biology : from enzyme inhibition and natural products synthesis to PET imaging by 6II-azae lectrocyclization2010

    • Author(s)
      Tanaka, K., et al.
    • Journal Title

      The Chemical Record

      Volume: 10 Pages: 119-139

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] A New "Microfluidic" Strategy for Practical Synthesis of Bioactive Natural Products2010

    • Author(s)
      Tanaka, K.
    • Journal Title

      J.of Synth. Org.Chem.Japan 68

      Pages: 124-135

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] In Vivo Imaging of Chemically Engineered Proteins and Cells by Oligosaccharides2010

    • Author(s)
      Tanaka, K.
    • Journal Title

      Trends in Glycoscience and Glycotechnology (TIGG) 22(In press)

    • NAID

      10027508089

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Renaissance of Traditional Organic Reactions under Microfluidic Conditions : A New Paradigm for Natural Products Synthesis2009

    • Author(s)
      K.Tanaka, K.Fukase
    • Journal Title

      Org.Process Res.Dev. 13

      Pages: 983-990

    • Related Report
      2010 Final Research Report
    • Peer Reviewed
  • [Journal Article] Library-directed Synthesis of N-Glycans : Synthesis of Sialic Acid-containing Complex-type N-Glycan on Solid-supports2009

    • Author(s)
      K.Tanaka, Y.Fujii, H.Tokimoto, Y.Mori, S.Tanaka, G.-m.Bao, E.R.O.Siwu, A.Nakayabu, K.Fukase
    • Journal Title

      Chem.Asian J. 4

      Pages: 574-580

    • Related Report
      2010 Final Research Report
    • Peer Reviewed
  • [Journal Article] Library-directed Synthesis of N-Glycans: Synthesis of Sialic Acid-containing Complex-type N-Glycan on Solid-supports.2009

    • Author(s)
      Tanaka, K.; Fujii, Y.; Tokimoto, H.; Mori, Y.; Tanaka, S.; Bao, G.-m.; Siwu, E.R.O.; Nakayabu, A.; Fukase, K.
    • Journal Title

      Chem. Asian J. 4

      Pages: 574-580

    • Related Report
      2009 Self-evaluation Report
    • Peer Reviewed
  • [Journal Article] Chemical N-Glycosylation by Asparagine under Combined Microfluidic/Batch Conditions2009

    • Author(s)
      Tanaka, K.; Miyagawa, Y.; Fukase, K.
    • Journal Title

      Synlett

      Pages: 1571-1574

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Renaissance of Traditional Organic Reactions under Microf luidic Conditions : A New Paradigm for Natural Products Synthesis2009

    • Author(s)
      Tanaka, K.; Fukase, K.
    • Journal Title

      Org. Process Res. Dev. 13

      Pages: 983-990

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Acid-Mediated Reactions under Microfluidic Conditions : A New Strategy for Practical Synthesis of Biofunctional Natu ral Products2009

    • Author(s)
      Tanaka, K.; Fukase, K.
    • Journal Title

      Beilstein Journal of Organic Chemistry-T hematic series "Flow Chemistry" 5

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Chemistry-based Labeling and Engineering on Proteins and Cell Surfaces : Application to Non-invasive Imaging of Oligosaccharide Derivatives2009

    • Author(s)
      Tanaka, K.; Minami, K.; Siwu, E.R.O.Siwu ; Fukase, K.
    • Journal Title

      Chemical Biology (Japanese Society for Chemical Biology) 2

      Pages: 7-12

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] A Practical Synthesis of Manβ(1-4)GlcNTroc Fragment via Microfl uidic β-Mannosylation2009

    • Author(s)
      Tanaka, K.; Mori, Y. ; Fukase, K.
    • Journal Title

      J. Carbohydr. Chem. 28

      Pages: 1-11

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Library-directed Synthesis of N-Glycans : Synthesis of Sialic Acid-c ontaining Complex-type N-Glycan on Solid-supports?2009

    • Author(s)
      Tanaka, K. ; Fujii, Y. ; Tokimoto, H. ; Mori, Y. ; Tanaka, S. ; Sao, G.-m. ; Siwu, E. R. O. ; Nakayabu,A. ;_Fukase_ K.
    • Journal Title

      Chem. Asian J. (in press)

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Journal Article] PET (Positron Emission Tomography) Imaging of Biomolecules Using Metal/DOTA Complexes : A New Collaborative Challenge by Chemists, Biologists, and Physicians for Future Diagnostics and Exploration of In vivo Dynamics2008

    • Author(s)
      K.Tanaka, K.Fukase
    • Journal Title

      Org.Biomol.Chem. 6

      Pages: 815-828

    • Related Report
      2010 Final Research Report
    • Peer Reviewed
  • [Journal Article] A Submicrogram-scale Protocol for Biomolecule-based PET Imaging via Rapid 6π-Azaelectrocyclization : First Visualization of Sialic Acid-dependent Circulatory Residence of Glycoproteins2008

    • Author(s)
      K.Tanaka, T.Masuyama, K.Hasegawa, T.Tahara, H.Mizuma, Y.Wada, Y.Watanabe, K.Fukase
    • Journal Title

      Angew.Chem.Int.Ed. 47

      Pages: 102-105

    • Related Report
      2010 Final Research Report
    • Peer Reviewed
  • [Journal Article] A Submicrogram-scale protocol for biomolecule-based PET imaging via rapid 6 -azaelectrocyclization: first visualization of sialic acid-dependent circulatory residence of glycoproteins.2008

    • Author(s)
      Tanaka, K.; Masuyama, T.; Hasegawa, K.; Tahara, T.; Mizuma, H.; Wada, Y.; Watanabe, Y.; Fukase, K.
    • Journal Title

      Angew. Chem. Int. Ed. 47

      Pages: 102-105

    • Related Report
      2009 Self-evaluation Report
    • Peer Reviewed
  • [Journal Article] PET (Positron Emission Tomography) Imaging of Biomolecules Using Metal/DOTA Complexes: A New Collaborative Challenge by Chemists, Biologists, and Physicians for Future Diagnostics and Exploration of In vivo Dynamics.2008

    • Author(s)
      Tanaka, K.; Fukase, K.
    • Journal Title

      Org. Biomol. Chem. 6

      Pages: 815-828

    • Related Report
      2009 Self-evaluation Report
    • Peer Reviewed
  • [Journal Article] Site-selective and Non-destructive Protein Labeling via Azaelectrocyclization-Induced Cascade Reactions2008

    • Author(s)
      Tanaka, K. ; Fujii, Y. ; Fukase, K.
    • Journal Title

      ChemBioChem 9

      Pages: 2392-2397

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Recent Advances in Positron Emission Tomography(PET)Imaging of Biomolecules : From Chemical Labeling to Cancer Diagnostics2008

    • Author(s)
      Tanaka, K. ; Fukase, K.
    • Journal Title

      Mini-Rev. Org. Chem. 5

      Pages: 153-162

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Journal Article] A Submicrogram-scale protocol for biomolecule-based PET imaging via rapid 6π-azzelectrocyclization: first visualization of sialic acid-dependent circulatory residence of glycoproteins2008

    • Author(s)
      Tanaka, K.
    • Journal Title

      Angew. Chem. Int. Ed. 47

      Pages: 102-105

    • Related Report
      2007 Annual Research Report
    • Peer Reviewed
  • [Journal Article] PET (Positron Emission Tomography) Imaging of Biomolecules Using Metal/DOTA Complexes: A New Collaborative Challeenge by Chemists, Biologists, and Physicians for Future Diagnostics and Exploration of In vivo Dynamics2008

    • Author(s)
      Tanaka, K.
    • Journal Title

      Org. Biomol. Chem. 6

      Pages: 815-828

    • Related Report
      2007 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Efficient Aldol Condensation in Aqueous Biphasic System under Microfluidic Conditions2008

    • Author(s)
      Tanaka, K.
    • Journal Title

      Tetrahedron Lett. 49

      Pages: 2010-2012

    • Related Report
      2007 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Highly Efficient α-Sialylation by Virtue of Fixed Dipole Effects of N-Phthalyl Group: Application to Continuous Flow Synthesis of α(2-3)-andα(2-6)-Neu5Ac-Gal Motifs by Microreactor2007

    • Author(s)
      Tanaka, K.
    • Journal Title

      J. Carbohydr. Chem. 26

      Pages: 369-394

    • Related Report
      2007 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Acceleration of Cu(I)-mediated Huisgen 1,3-Dipolar Cycloaddition by Histidine DErivatives2007

    • Author(s)
      Tanaka, K.
    • Journal Title

      Tetrahedron Lett. 48

      Pages: 6475-6479

    • Related Report
      2007 Annual Research Report
    • Peer Reviewed
  • [Journal Article] A Whole Cell-based In Vivo Imaging and Tumor Targetingvia Cell-surface Labeling and Engineering by 6π-Azaelectr ocyclization

    • Author(s)
      Tanaka, K.; Minami, K.; Tahara, T.; Fujii, Y.; Siwu, E.R.O.; Nozaki, S.; Onoe, H.; Yokoi, S.; Koyama, K.; Watanabe, Y.; Fukase, K.
    • Journal Title

      Chem Med Chem (In press)

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] A Combined 6π-Azaelectrocyclization/Staudinger Approach to Protein & Cell Engineering : Non-Invasive Tumor Targeting by N-Glycan-Engineered Lymphocytes

    • Author(s)
      Tanaka, K.; Minami, K.; Tahara, T.; Siwu, E.R.O.; Koyama, K.; Nozaki, S.; Onoe, H.; Watanabe, Y.; Fukase, K.
    • Journal Title

      J.Carbohydr.Chem. (In press)

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Presentation] 効率的結合形成反応から始まるシンセティックバイオロジーの新戦略2011

    • Author(s)
      田中克典
    • Organizer
      「生体分子の化学」シンポジウム,Host:伊藤幸成主任
    • Place of Presentation
      独立行政法人理化学研究所
    • Year and Date
      2011-01-21
    • Related Report
      2010 Final Research Report
  • [Presentation] 効率的結合形成反応から始まるシンセティックバイオロジーの新戦略2011

    • Author(s)
      田中克典
    • Organizer
      「生体分子の化学」シンポジウム
    • Place of Presentation
      埼玉県和光市、独立行政法人理化学研究所(招待講演)
    • Year and Date
      2011-01-21
    • Related Report
      2010 Annual Research Report
  • [Presentation] コアフコースを持つ複合型N-結合型糖鎖の合成研究2011

    • Author(s)
      田中克典、宮川卓也
    • Organizer
      日本化学会第91回春季年会
    • Place of Presentation
      神奈川大学
    • Related Report
      2010 Annual Research Report
  • [Presentation] Isolation and Cytotoxicity of Ursolic Acid Derivatives from Bangladeshi Medicinal Plants, Saurauja roxburghii2011

    • Author(s)
      田中克典、MAZUMDER, Kishor
    • Organizer
      日本化学会第91回春季年会
    • Place of Presentation
      神奈川大学
    • Related Report
      2010 Annual Research Report
  • [Presentation] N5-Acシアル酸糖供与体を用いた実践的α-シアリル化反応2011

    • Author(s)
      田中克典、内梨洋介
    • Organizer
      日本化学会第91回春季年会
    • Place of Presentation
      神奈川大学
    • Related Report
      2010 Annual Research Report
  • [Presentation] Pep TenChipへの糖鎖/ペプチド導入の革新的導入法と生体分子社会構築のデザイン2010

    • Author(s)
      田中克典
    • Organizer
      ハイペップ研究所2010紅葉ワークショップ
    • Place of Presentation
      (株)ハイペップ研究所(京都府)(招待講演)
    • Year and Date
      2010-12-03
    • Related Report
      2010 Annual Research Report
  • [Presentation] A New Strategy in Synthetic Biology: From Enzyme Inhibition, Natural Products Synthesis to PET Imaging by 6π-Azaelectrocyclizations2010

    • Author(s)
      田中克典
    • Organizer
      Departmental Seminar at Department of Chemistry, Georgia State university,Host : Professor Binghe Wang
    • Place of Presentation
      Atlanta
    • Year and Date
      2010-11-18
    • Related Report
      2010 Final Research Report
  • [Presentation] A New Strategy in Synthetic Biology : From Enzyme Inhibition, Natural Products Synthesis to PET Imaging by 6II-Azaelectrocyclizations2010

    • Author(s)
      田中克典
    • Organizer
      Departmental Seminar at Department of Chemistry, Georgia State university
    • Place of Presentation
      Atlanta, USA(招待講演)
    • Year and Date
      2010-11-18
    • Related Report
      2010 Annual Research Report
  • [Presentation] A New Strategy in Synthetic Biology : From Enzyme Inhibition, Natural Products Synthesis to PET Imaging by 6π-Azaelectrocyclizations2010

    • Author(s)
      田中克典
    • Organizer
      Departmental Seminar at Departments of Chemistry and Medicinal Chemistry, University of Michigan,Host : Anna Mapp
    • Place of Presentation
      Michigan
    • Year and Date
      2010-11-16
    • Related Report
      2010 Final Research Report
  • [Presentation] A New Strategy in Synthetic Biology : From Enzyme Inhibition, Natural Products Synthesis to PET Imaging by 6II-Azaelectrocyclizations2010

    • Author(s)
      田中克典
    • Organizer
      Departmental Seminar at Departments of Chemistry and Medicinal Chemistry, University of Michigan
    • Place of Presentation
      Michigan, USA(招待講演)
    • Year and Date
      2010-11-16
    • Related Report
      2010 Annual Research Report
  • [Presentation] A New Strategy in Synthetic Biology : From Enzyme Inhibition, Natural Products Synthesis to PET Imaging by 6π-Azaelectrocyclizations2010

    • Author(s)
      田中克典
    • Organizer
      Departmental Seminar at Department of Chemistry, The University of Toledo,Host : Kana Yamamoto
    • Place of Presentation
      Ohio
    • Year and Date
      2010-11-15
    • Related Report
      2010 Final Research Report
  • [Presentation] A New Strategy in Synthetic Biology : From Enzyme Inhibition, Natural Products Synthesis to PET Imaging by 6II-Azaelectrocyclizations2010

    • Author(s)
      田中克典
    • Organizer
      Departmental Seminar at Department of Chemistry, The University of Toledo
    • Place of Presentation
      Ohio, USA(招待講演)
    • Year and Date
      2010-11-15
    • Related Report
      2010 Annual Research Report
  • [Presentation] A New Strategy in Synthetic Biology : From Enzyme Inhibition, Natural Products Synthesis to PET Imaging by 6π-Azaelectrocyclizations2010

    • Author(s)
      田中克典
    • Organizer
      Departmental Seminar at Wayne State university,Host : Professor Zhongwu Guo
    • Place of Presentation
      Detroit
    • Year and Date
      2010-11-12
    • Related Report
      2010 Final Research Report
  • [Presentation] A New Strategy in Synthetic Biology : From Enzyme Inhibition, Natural Products Synthesis to PET Imaging by 6II-Azaelectrocyclizations2010

    • Author(s)
      田中克典
    • Organizer
      Departmental Seminar at Wayne Stateuniversity
    • Place of Presentation
      Detroit, USA(招待講演)
    • Year and Date
      2010-11-12
    • Related Report
      2010 Annual Research Report
  • [Presentation] A New Strategy in Synthetic Biology : From Enzyme Inhibition, Natural Products Synthesis to PET Imaging by 6π-Azaelectrocyclizations2010

    • Author(s)
      田中克典
    • Organizer
      Departmental Seminar at North Carolina State university,Host : Christian Melander
    • Place of Presentation
      North Carolina
    • Year and Date
      2010-11-10
    • Related Report
      2010 Final Research Report
  • [Presentation] A New Strategy in Synthetic Biology : From Enzyme Inhibition, Natural Products Synthesis to PET Imaging by 6II-Azaelectrocyclizations, Department of Chemistry2010

    • Author(s)
      田中克典
    • Organizer
      Departmental Seminar at North Carolina State university
    • Place of Presentation
      Raleigh, North Carolina, USA(招待講演)
    • Year and Date
      2010-11-10
    • Related Report
      2010 Annual Research Report
  • [Presentation] New strategy from synthetic chemistry & molecular imaging, Asian Communications of Glycobiology and Glycotechnology2010

    • Author(s)
      田中克典
    • Organizer
      2nd Annual Conference for Asian Communicationsof Glycobiology and Glycotechnology
    • Place of Presentation
      台湾
    • Year and Date
      2010-10-29
    • Related Report
      2010 Final Research Report
  • [Presentation] Visualization of N-Glycan dynamics in living animals2010

    • Author(s)
      田中克典
    • Organizer
      new strategy from synthetic chemistry & molecular imaging, Asian Communications of Glycobiology and Glycotechnology (ACGG)
    • Place of Presentation
      台北(台湾)(招待講演)
    • Year and Date
      2010-10-29
    • Related Report
      2010 Annual Research Report
  • [Presentation] 実用的合成を指向したマイクロフロー反応の適応範囲と可能性:生理活性天然物の合成を例として2010

    • Author(s)
      田中克典
    • Organizer
      塩野義製薬株式会社セミナー
    • Place of Presentation
      大阪
    • Year and Date
      2010-10-12
    • Related Report
      2010 Final Research Report
  • [Presentation] 実用的合成を指向したマイクロフロー反応の適応範囲と可能性:生理活性天然物の合成を例として2010

    • Author(s)
      田中克典
    • Organizer
      塩野義製薬株式会社における招待講演
    • Place of Presentation
      塩野義製薬株式会社(大阪府)
    • Year and Date
      2010-10-12
    • Related Report
      2010 Annual Research Report
  • [Presentation] 非侵襲的イメージングを用いたタンパク質、細胞、およびデンドリマー上のN-結合型糖鎖の機能解析-N-結合型糖鎖による非侵襲的イメージングとターゲティング-2010

    • Author(s)
      田中克典
    • Organizer
      第59回高分子討論会
    • Place of Presentation
      北海道大学
    • Year and Date
      2010-09-15
    • Related Report
      2010 Final Research Report
  • [Presentation] Azaelectrocyclization-Based Labeling & Engineering Allow Non-Invasive Imaging of Cellular Trafficking and Tumor Targeting by Lymphocytes2010

    • Author(s)
      Katsunori Tanaka
    • Organizer
      World Molecular Imaging Congress (WMIC)
    • Place of Presentation
      京都国際会館(京都府)
    • Year and Date
      2010-09-09
    • Related Report
      2010 Annual Research Report
  • [Presentation] 基質隣接効果による初めての"head-to-head"イミン二量化反応:縮環1,2-ジアゼチジンの直接的[2+2]合成2010

    • Author(s)
      田中克典、広崎真司
    • Organizer
      第37回有機反応懇談会
    • Place of Presentation
      京都大学宇治キャンパス
    • Year and Date
      2010-08-02
    • Related Report
      2010 Annual Research Report
  • [Presentation] 革新的結合形成反応の糖鎖科学への応用:マイクロフロー/固相合成システムによるN-結合型糖鎖の合成と非侵襲的イメージング2010

    • Author(s)
      田中克典
    • Organizer
      財団法人野口研究所セミナー,Host:水野真盛研究員
    • Place of Presentation
      東京
    • Year and Date
      2010-05-28
    • Related Report
      2010 Final Research Report
  • [Presentation] 革新的結合形成反応の糖鎖科学への応用:マイクロフロー/固相合成システムによるN-結合型糖鎖の合成と非侵襲的イメージング2010

    • Author(s)
      田中克典
    • Organizer
      財団法人野口研究所での招待講演
    • Place of Presentation
      財団法人野口研究所,東京
    • Year and Date
      2010-05-28
    • Related Report
      2010 Annual Research Report
  • [Presentation] マイクロフローシステムを用いた実用的なa-シアリル化反応の開発とポリシアル酸合成への展開2010

    • Author(s)
      田中克典、内梨洋介
    • Organizer
      第11回 関西グライコサイエンスフォーラム
    • Place of Presentation
      大阪市立大学
    • Year and Date
      2010-05-15
    • Related Report
      2010 Annual Research Report
  • [Presentation] STELLA+標識キットの開発と生体内イメージング2010

    • Author(s)
      田中克典
    • Organizer
      (株)キシダ化学セミナー
    • Place of Presentation
      兵庫
    • Year and Date
      2010-05-12
    • Related Report
      2010 Final Research Report
  • [Presentation] STELLA+標識キットの開発と生体内イメージング2010

    • Author(s)
      田中克典
    • Organizer
      (株)キシダ化学での招待講演
    • Place of Presentation
      (株)キシダ化学 神戸
    • Year and Date
      2010-05-12
    • Related Report
      2010 Annual Research Report
  • [Presentation] 高速化学反応による細胞表層への糖鎖エンジニアリングと生体内イメージング2010

    • Author(s)
      田中克典
    • Organizer
      大阪大学グローバルCOEオルガネラネットワーク医学創成プログラム 分野融合若手研究交流会
    • Place of Presentation
      千里ライフサイエンスセンター、大阪(招待講演)
    • Year and Date
      2010-04-12
    • Related Report
      2010 Annual Research Report
  • [Presentation] A New Strategy in Synthetic Biology : From Enzyme Inhibition, Natural Products Synthesis to PET Imaging by 6π-Azaelectrocyclizations2010

    • Author(s)
      田中克典
    • Organizer
      Departmental Seminar at Center for Chemical Methodology and Library Department,Host : Professor John A.Porco Jr.
    • Place of Presentation
      Boston University
    • Year and Date
      2010-03-03
    • Related Report
      2010 Final Research Report
  • [Presentation] A New Strategy in Synthetic Biology : From Enzyme Inhibition, Natural Products Synthesis to PET Imaging by 6π-Azaelectrocyclizations2010

    • Author(s)
      田中克典
    • Organizer
      Boston Universityでの特別講演
    • Place of Presentation
      Center for Chemical Methodology and Library Department, Boston University, Boston, U.S.A.
    • Year and Date
      2010-03-03
    • Related Report
      2009 Annual Research Report
  • [Presentation] A New Strategy in Synthetic Biology : From Enzyme Inhibition, Natural Products Synthesis to PET Imaging by 6π-Azaelectrocyclizations2010

    • Author(s)
      田中克典
    • Organizer
      Departmental Seminar at Department of Radiology, Memorial Sloan-Kettering Cancer Center,Host : Dr Jason S.Lewis
    • Place of Presentation
      New York
    • Year and Date
      2010-03-01
    • Related Report
      2010 Final Research Report
  • [Presentation] A New Strategy in Synthetic Biology : From Enzyme Inhibition, Natural Products Synthesis to PET Imaging by 6π-Azaelectrocyclizations2010

    • Author(s)
      田中克典
    • Organizer
      Memorial Sloan-Kettering Cancer Centerでの特別講演
    • Place of Presentation
      Department of Radiology, Memorial Sloan-Kettering Cancer Center, New York, U.S.A.
    • Year and Date
      2010-03-01
    • Related Report
      2009 Annual Research Report
  • [Presentation] A New Strategy in Synthetic Biology : From Enzyme Inhibition, Natural Products Synthesis to PET Imaging by 6π-Azaelectrocyclizations2010

    • Author(s)
      田中克典
    • Organizer
      Departmental Seminar at Department of Chemistry and Chemical Biology,Host : Professor Gregory Verdine
    • Place of Presentation
      Harvard University
    • Year and Date
      2010-02-26
    • Related Report
      2010 Final Research Report
  • [Presentation] A New Strategy in Synthetic Biology : From Enzyme Inhibition, Natural Products Synthesis to PET Imaging by 6π-Azaelectrocyclizations2010

    • Author(s)
      由中克典
    • Organizer
      Harvard Universityでの特別講演
    • Place of Presentation
      Department of Chemistry and Chemical Biology, Harvard University, Cambridge, U.S.A.
    • Year and Date
      2010-02-26
    • Related Report
      2009 Annual Research Report
  • [Presentation] A New Strategy in Synthetic Biology : From Enzyme Inhibition, Natural Products Synthesis to PET Imaging by 6π-Azaelectro cyclizations2010

    • Author(s)
      田中克典
    • Organizer
      第三回先端的分析法講演会
    • Place of Presentation
      大阪大学(大阪)
    • Year and Date
      2010-01-19
    • Related Report
      2009 Annual Research Report
  • [Presentation] Convergent Synthesis of N-linked Glycan through Microfluidic & Solid-supported Glycosylation2010

    • Author(s)
      Katsunori Tanaka
    • Organizer
      The 2010 International Chemical Congress of Pacific Basin Societies (Pacifichem 2010)
    • Place of Presentation
      Honolulu, USA
    • Related Report
      2010 Annual Research Report
  • [Presentation] Unprecedented [2+2]-Condensation of Imines : Remarkable Substituent Effects and Synthetic Applications2010

    • Author(s)
      Katsunori Tanaka
    • Organizer
      The 2010 International Chemical Congress of Pacific Basin Societies (Pacifichem 2010)
    • Place of Presentation
      Honolulu, USA
    • Related Report
      2010 Annual Research Report
  • [Presentation] Azaelectrocyclization-Based Labeling and Engineering of Proteins & Living Cells : Application to Non-invasive Imaging of N-Glycans2010

    • Author(s)
      Katsunori Tanaka
    • Organizer
      The 2010 International Chemical Congress of Pacific Basin Societies (Pacifichem 2010)
    • Place of Presentation
      Honolulu, USA
    • Related Report
      2010 Annual Research Report
  • [Presentation] Cytotoxic Ursolic Acid Derivatives from Bangladeshi Medicinal Plants, Saurauja roxburghii2010

    • Author(s)
      Katsunori Tanaka, Kishor Mazumder
    • Organizer
      The 2010 International Chemical Congress of Pacific Basin Societies (Pacifichem 2010)
    • Place of Presentation
      Honolulu, USA
    • Related Report
      2010 Annual Research Report
  • [Presentation] Synthesis of α-Sialosides under Microfluidic Conditions2010

    • Author(s)
      K.Tanaka, Y.Uchinashi
    • Organizer
      The 2010 International Chemical Congress of Pacific Basin Societies (Pacifichem 2010)
    • Place of Presentation
      Honolulu, USA
    • Related Report
      2010 Annual Research Report
  • [Presentation] Synthesis of Polylysine-Based N-Glycan Dendrimers as Noninvasive Imaging Tracers2010

    • Author(s)
      K.Tanaka
    • Organizer
      5th International Peptide Symposium
    • Place of Presentation
      京都国際会館(京都府)
    • Related Report
      2010 Annual Research Report
  • [Presentation] Synthetic Approach for Elucidating Glycan Codes2010

    • Author(s)
      Katsunori Tanaka, Koichi Fukase
    • Organizer
      The 5th International Conference on Cutting-Edge Organic Chemistry in Asia (ICCEOCA-5) / The 1st New phase International Conference on Cutting-Edge Organic Chemistry in Asia (NICCEOCA-1)
    • Place of Presentation
      Hsinchu, Taiwan(招待講演)
    • Related Report
      2010 Annual Research Report
  • [Presentation] Synthesis of Polylysine-Based Glycodendrimer Through Self-Activating Click Reaction2010

    • Author(s)
      Katsunori Tanaka, Tohru Watanabe
    • Organizer
      The Sixth International Symposium on Integrated Synthesis (ISIS-6)
    • Place of Presentation
      シーサイドホテル舞子ビラ(兵庫県)
    • Related Report
      2010 Annual Research Report
  • [Presentation] Microfluidic Procedures in Oligosaccharides Synthesis : Innovative Chemical Transformation to Sialoglycans2010

    • Author(s)
      K.Tanaka, Y.Uchinashi
    • Organizer
      International Symposium on Environmentally Benign Synthesis
    • Place of Presentation
      大阪大学中之島センター(大阪府)
    • Related Report
      2010 Annual Research Report
  • [Presentation] アスパラギン結合型糖タンパク質糖鎖の合成を指向したマイクロフロー/バッチ混合系でのN-グリコシル化反応の開発2010

    • Author(s)
      田中克典、宮川卓也
    • Organizer
      第27回有機合成化学セミナー
    • Place of Presentation
      シーサイドホテル舞子ビラ神戸
    • Related Report
      2010 Annual Research Report
  • [Presentation] Microfluidic α-Sialylation2010

    • Author(s)
      Katsunori Tanaka, Koichi Fukase
    • Organizer
      Sialoglyco 2010
    • Place of Presentation
      Potsdam, Germany
    • Related Report
      2010 Annual Research Report
  • [Presentation] Noninvasive PET & Fluorescence Imaging of N-Glycans : Sialic Acid-Dependent In Vivo Dynamics of Proteins, Glycoclusters and Living Cells2010

    • Author(s)
      Katsunori Tanaka
    • Organizer
      Sialoglyco 2010
    • Place of Presentation
      Potsdam, Germany
    • Related Report
      2010 Annual Research Report
  • [Presentation] Synthesis of α-Sialosides under Microfluidic Conditions2010

    • Author(s)
      Katsunori Tanaka, Koichi Fukase
    • Organizer
      Sialoglyco 2010
    • Place of Presentation
      Potsdam, Germany
    • Related Report
      2010 Annual Research Report
  • [Presentation] Synthesis of Galβ(1-3)[NeuAcα(2-6)]GlcNAc β(1-2)Man Motif as Molecular Probes for Biological Evaluation2010

    • Author(s)
      Katsunori Tanaka, Guang-ming Bao
    • Organizer
      Sialoglyco 2010
    • Place of Presentation
      Potsdam, Germany
    • Related Report
      2010 Annual Research Report
  • [Presentation] Practical Microfluidic Procedures for α-Sialylation2010

    • Author(s)
      K.Tanaka, Y.Uchinashi
    • Organizer
      The 25th International Carbohydrate Symposium (ICS 2010)
    • Place of Presentation
      幕張メッセ(千葉県)
    • Related Report
      2010 Annual Research Report
  • [Presentation] Synthetic Study and Biological Investigation of New N-Glycan in Mouse Brain2010

    • Author(s)
      K.Tanaka, G.M.Bao
    • Organizer
      The 25th International Carbohydrate Symposium (ICS 2010)
    • Place of Presentation
      幕張メッセ(千葉県)
    • Related Report
      2010 Annual Research Report
  • [Presentation] Chemistry-based Protein & Cell-Surface Engineering by N-Glycans2010

    • Author(s)
      K.Tanaka
    • Organizer
      The 25th International Carbohydrate Symposium (ICS 2010)
    • Place of Presentation
      幕張メッセ(千葉県)
    • Related Report
      2010 Annual Research Report
  • [Presentation] Remarkable Structural Dependency of N-Glycan Clusters on In Vivo Dynamics2010

    • Author(s)
      K.Tanaka, E.R.Siwu
    • Organizer
      The 25th International Carbohydrate Symposium (ICS 2010)
    • Place of Presentation
      幕張メッセ(千葉県)
    • Related Report
      2010 Annual Research Report
  • [Presentation] Synthesis of new probes for chemical glycobiology : application to PET and fluorescent imaging of glycoproteins, glycoclusters, and living cells2010

    • Author(s)
      Katsunori Tanaka, Koichi Fukase
    • Organizer
      1st Asian Chemical Biology Conference
    • Place of Presentation
      ソウル大学(韓国)(招待講演)
    • Related Report
      2010 Annual Research Report
  • [Presentation] マイクロフロー系反応を活用したシアル酸含有糖鎖の実用的合成と分子イメージングへの展開2010

    • Author(s)
      田中克典、内梨洋介
    • Organizer
      日本ケミカルバイオロジー学会 第5回年会
    • Place of Presentation
      慶応大学(神奈川県)
    • Related Report
      2010 Annual Research Report
  • [Presentation] Unprecedented [2+2]-Condensation of Imines : Simulataneous C-C & N-N Bond Formations to 1,2-Diazetidenes2010

    • Author(s)
      Katsunori Tanaka, Shinji Hirosaki
    • Organizer
      The 21st French-Japanese Symposium on Medicinal and Fine Chemistry (FJS2010)
    • Place of Presentation
      京都ガーデンパレス(京都府)
    • Related Report
      2010 Annual Research Report
  • [Presentation] Isolation and Cytotoxic Activity of Ursolic Acid Derivatives from Bangladeshi Medicinal Plants, Saurauja roxburghii2010

    • Author(s)
      Katsunori Tanaka, Kishor Mazumder
    • Organizer
      The 21st French-Japanese Symposium on Medicinal and Fine Chemistry (FJS2010)
    • Place of Presentation
      京都ガーデンパレス(京都府)
    • Related Report
      2010 Annual Research Report
  • [Presentation] Non-Invasive In Vivo Imaging of N-Glycans2010

    • Author(s)
      Katsunori Tanaka
    • Organizer
      International Symposium on Organelle Networks : Interface among Infection-Immunity, Cell Biology and Glycobiology
    • Place of Presentation
      千里ライフサイエンスセンター(大阪府)
    • Related Report
      2010 Annual Research Report
  • [Presentation] マイクロフロー/バッチ混合系を用いたN-グリコシル化反応2010

    • Author(s)
      宮川卓也, 田中克典, 深瀬浩一
    • Organizer
      第90回日本化学会春季年会
    • Place of Presentation
      近畿大学(大阪)
    • Related Report
      2009 Annual Research Report
  • [Presentation] 広幅経路のマイクロミキサーを活用した実用的α-シアリル化反応2010

    • Author(s)
      内梨洋介, 田中克典, 深瀬浩一
    • Organizer
      第90回日本化学会春季年会
    • Place of Presentation
      近畿大学(大阪)
    • Related Report
      2009 Annual Research Report
  • [Presentation] マイクロフローシステムを用いたグリコシル重合反応の制御2010

    • Author(s)
      中薮愛子, 内梨洋介, 田中克典, 深瀬浩一
    • Organizer
      第90回日本化学会春季年会
    • Place of Presentation
      近畿大学(大阪)
    • Related Report
      2009 Annual Research Report
  • [Presentation] イミン誘導体の形式的[2+2]反応と合成的展開2010

    • Author(s)
      田中克典, Eric R.O.Siwu, 岩田隆幸, 広崎真司, 南香莉, 宮川卓也, Jose Isagani, B.Janairo, 深瀬浩一
    • Organizer
      第90回日本化学会春季年会
    • Place of Presentation
      近畿大学(大阪)
    • Related Report
      2009 Annual Research Report
  • [Presentation] 6π-電子環状反応を用いたタンパク質や細胞表層上への糖鎖エンジニアリング2010

    • Author(s)
      南香莉, Eric R.0.Siwu, 田中克典, 深瀬浩一
    • Organizer
      第90回日本化学会春季年会
    • Place of Presentation
      近畿大学(大阪)
    • Related Report
      2009 Annual Research Report
  • [Presentation] Acid-Mediated Reactions under Microfluidic Conditions : A New Strategy for Practical Synthesis of Biofunctional Natural Products2010

    • Author(s)
      Katsunori Tanaka, Koichi Fukase
    • Organizer
      11^<th> International Conference on Microreaction Technology (IMRET11)
    • Place of Presentation
      Kyoto Research Park (Kyoto)
    • Related Report
      2009 Annual Research Report
  • [Presentation] Integrated Microfluidic/Batch Conditions for Practical Glyco sylation2010

    • Author(s)
      Takuya Miyagawa, Yasutaka Mori, Katsunori Tanaka, Koichi Fukase
    • Organizer
      11^<th> International Conference on Microreaction Technology (IMRET11)
    • Place of Presentation
      Kyoto Research Park (Kyoto)
    • Related Report
      2009 Annual Research Report
  • [Presentation] タンパク質および細胞上での革新的化学反応を基盤とする糖鎖関連物質の非侵襲的イメージング2009

    • Author(s)
      田中克典
    • Organizer
      第7回糖鎖科学コンソーシアムシンポジウム,千里ライフサイエンスセンター
    • Place of Presentation
      大阪
    • Year and Date
      2009-12-07
    • Related Report
      2010 Final Research Report
  • [Presentation] マイクロ系内でのグリコシルカチオンの制御に基づく実用的フロー糖鎖合成2009

    • Author(s)
      中薮愛子, 田中克典, 深瀬浩一
    • Organizer
      第29回有機合成若手セミナー明日の有機合成を担う人のために
    • Place of Presentation
      甲南大学ポートアイランド(神戸)
    • Year and Date
      2009-11-24
    • Related Report
      2009 Annual Research Report
  • [Presentation] 高速化学反応による細胞表層への糖鎖エンジニアリングと生体内イメージング2009

    • Author(s)
      田中克典
    • Organizer
      大阪大学グローバルCOE オルガネラネットワーク医学創成プログラム 分野融合若手研究交流会
    • Place of Presentation
      伊勢かぐらばリゾート(伊勢)
    • Year and Date
      2009-10-05
    • Related Report
      2009 Annual Research Report
  • [Presentation] In Vivo Imaging of N-Glycan Dendrimers by Fluorescence-and Positron Emission Tomography (PET)2009

    • Author(s)
      Katsunori Tanaka, Eric R.O.Siwu, Kaori Minami, Koki Hasegawa, Satoshi N ozaki, Yousuke Kanayama, Yasuyoshi Watanabe, Koi chi Koyama, Koichi Fukase
    • Organizer
      Combinatorial Chemistry and Chemical Biology (CCCB)
    • Place of Presentation
      Senri Life Science Center (Osaka)
    • Year and Date
      2009-09-24
    • Related Report
      2009 Annual Research Report
  • [Presentation] Nanomolar-Scale Lysine Labeling by 6π-Azaelectrocyclizati on : Biomolecule- and Whole Cell-Based In Vivo Imaging and Tumor Targeting2009

    • Author(s)
      Katsunori Tanaka, Kaori Minami, Eric R.O.Siwu, Tsuyoshi Tahara, Satoshi Nozaki, Yasuyoshi Watanabe, Koichi Koyama, Satomi Yokoi, Koichi Fukase
    • Organizer
      Combinatorial Chemistry and Chemical Biology (CCCB)
    • Place of Presentation
      Senri Life Science Center (Osaka)
    • Year and Date
      2009-09-24
    • Related Report
      2009 Annual Research Report
  • [Presentation] Convergent Synthesis of N-linked Glycan through Microfluidic & Solid-supported Glycosylation2009

    • Author(s)
      Katsunori Tanaka, Aiko Nakayabu, Guang-ming Bao, Yohei Fujii, Koichi Fukase
    • Organizer
      Combinatorial Chemistry and Chemical Biology (CCCB)
    • Place of Presentation
      Senri Life Science Center (Osaka)
    • Year and Date
      2009-09-24
    • Related Report
      2009 Annual Research Report
  • [Presentation] Integrated Microfluidic/Batch Conditions for Practical N-Gl ycosylation and β-Mannosylation2009

    • Author(s)
      Katsunori Tanaka, Takuya Miyagawa, Yasutaka Mori, Koichi Fukase
    • Organizer
      Combinatorial Chemistry and Chemical Biology (CCCB)
    • Place of Presentation
      Senri Life Science Center (Osaka)
    • Year and Date
      2009-09-24
    • Related Report
      2009 Annual Research Report
  • [Presentation] 細胞上での革新的有機合成反応:細胞丸ごとをトレーサーとしたインビボイメージングと癌組織のターゲティング2009

    • Author(s)
      田中克典、南香莉、Eric R.O.Siwu、田原強、野崎聡、渡辺恭良、小山幸一、深瀬浩一
    • Organizer
      生体機能関連化学シンポジウム バイオテクノロジー部会シンポジウム
    • Place of Presentation
      九州大学(福岡)
    • Year and Date
      2009-09-15
    • Related Report
      2009 Annual Research Report
  • [Presentation] A New Strategy in Synthetic Biology : From Enzyme Inhibition, Natural Products Synthesis to PET Imaging by 6π-Azaelectrocyclizations2009

    • Author(s)
      田中克典
    • Organizer
      大阪大学臨床医工学・情報学スキルアップ講座
    • Place of Presentation
      大阪大学中之島センター(大阪)
    • Year and Date
      2009-09-12
    • Related Report
      2009 Annual Research Report
  • [Presentation] Chemistry-based Protein & Cell-Surface Engineering through 6π-Azaelectrocyclization2009

    • Author(s)
      Katsunori Tanaka, Koichi Fukase
    • Organizer
      The 25^<th> Naito Conference
    • Place of Presentation
      Chateraise Gateaux Kingdom(Hokkaido)
    • Year and Date
      2009-09-10
    • Related Report
      2009 Annual Research Report
  • [Presentation] 蛍光およびPETによるN-結合型糖鎖クラスターのインビボイメージング2009

    • Author(s)
      Eric R.O.Siwu、南香莉、長谷川功紀、野崎聡、金山洋介、小山幸一、渡辺恭良、田中克典、深瀬浩一
    • Organizer
      第29回日本糖質学会年会
    • Place of Presentation
      世界生活文化センター(岐阜)
    • Year and Date
      2009-09-09
    • Related Report
      2009 Annual Research Report
  • [Presentation] マイクロフロー/バッチ混合系を用いたグリコシル化反応の開発2009

    • Author(s)
      宮川卓也, 森康貴, 田中克典, 深瀬浩一
    • Organizer
      第29回日本糖質学会年会
    • Place of Presentation
      世界生活文化センター(岐阜)
    • Year and Date
      2009-09-09
    • Related Report
      2009 Annual Research Report
  • [Presentation] A New Strategy in Synthetic Biology : From Enzyme Inhibition, Natural Products Synthesis to PET Imaging by 6π-Azaelectrocyclizations2009

    • Author(s)
      田中克典
    • Organizer
      Departmental Seminar at Department of Chemistry, Host : Professor Daesung Lee
    • Place of Presentation
      The University of Illinois at Chicago
    • Year and Date
      2009-09-01
    • Related Report
      2010 Final Research Report
  • [Presentation] A New Strategy in Synthetic Biology : From Enzyme Inhibition, Natural Products Synthesis to PET Imaging by 6π-Azaelectrocyclizations2009

    • Author(s)
      田中克典
    • Organizer
      The University of Illinoisでの特別講演
    • Place of Presentation
      Department of Chemistry, The University of Illinois, Chicago, U.S.A.
    • Year and Date
      2009-09-01
    • Related Report
      2009 Annual Research Report
  • [Presentation] A New Strategy in Synthetic Biology : From Enzyme Inhibition, Natural Products Synthesis to PET Imaging by 6π-Azaelectrocyclizations2009

    • Author(s)
      田中克典
    • Organizer
      Departmental Seminar at Department of Chemistry, Host : Professor Christopher J.Douglas
    • Place of Presentation
      University of Minnesota
    • Year and Date
      2009-08-27
    • Related Report
      2010 Final Research Report
  • [Presentation] A New Strategy in Synthetic Biology : From Enzyme Inhibition, Natural Products Synthesis to PET Imaging by 6π-Azaelectrocyclizations2009

    • Author(s)
      田中克典
    • Organizer
      University of Minnesotaでの特別講演
    • Place of Presentation
      Department of Chemistry, University of Minnesota, Minneapolis, U.S.A.
    • Year and Date
      2009-08-27
    • Related Report
      2009 Annual Research Report
  • [Presentation] A New Strategy in Synthetic Biology : From Enzyme Inhibition, Natural Products Synthesis to PET Imaging by 6π-Azaelectrocyclizations2009

    • Author(s)
      田中克典
    • Organizer
      Departmental Seminar at Department of Chemistry and Molecular Biology, Host : Professor Gregory R.Cook
    • Place of Presentation
      NDSU North Dakota State University
    • Year and Date
      2009-08-25
    • Related Report
      2010 Final Research Report
  • [Presentation] A New Strategy in Synthetic Biology : From Enzyme Inhibition, Natural Products Synthesis to PET Imaging by 6π-Azaelectrocyclizations2009

    • Author(s)
      田中克典
    • Organizer
      NDSU North Dakota State Universityでの特別講演
    • Place of Presentation
      Department of Chemistry and Molecular Biology, NDSU North Dakota State University, Fargo, U.S.A.
    • Year and Date
      2009-08-25
    • Related Report
      2009 Annual Research Report
  • [Presentation] タンパク質、および細胞上での革新的有機合成反応の開発:6π-アザ電子環状反応を用いたシンセティックバイオロジー2009

    • Author(s)
      Eric R.O.Siwu、南香莉、田中克典、深瀬浩一
    • Organizer
      第36回有機反応懇談会
    • Place of Presentation
      関西学院大学 三田(神戸)
    • Year and Date
      2009-08-03
    • Related Report
      2009 Annual Research Report
  • [Presentation] マイクロフロー/バッチ混合系を用いたN-グリコシル化反応の開発2009

    • Author(s)
      宮川卓也、田中克典、深瀬浩一
    • Organizer
      第36回有機反応懇談会
    • Place of Presentation
      関西学院大学三田(神戸)
    • Year and Date
      2009-08-03
    • Related Report
      2009 Annual Research Report
  • [Presentation] A New Strategy in Synthetic Biology : From Enzyme Inhibition, Natural Products Synthesis to PET Imaging by 6π-Azaelectrocyclizations2009

    • Author(s)
      田中克典
    • Organizer
      東北大学Grobal COEシンポジウム
    • Place of Presentation
      作並温泉(仙台)
    • Year and Date
      2009-08-02
    • Related Report
      2009 Annual Research Report
  • [Presentation] Convergent Synthesis of N-linked Sialoglycan on Solid-Supports2009

    • Author(s)
      Guang-ming Bao, Yohei Fujii, Hiroomi Tokimoto, Yasutaka Mori, Shin-ichi Tanaka, Eric R.O.Siwu, Aiko Nakayabu, Katsunori Tanaka, Koichi Fukase
    • Organizer
      International Workshop of Biofunctional Chemistry for Young Scientists
    • Place of Presentation
      Awaji Yumebutai (Awaji)
    • Year and Date
      2009-07-22
    • Related Report
      2009 Annual Research Report
  • [Presentation] Practical α-Sialylation under Microfluidic Conditions2009

    • Author(s)
      Yousuke Uchinashi, Sayaka Umeda, Katsunori Tanaka, Koichi Fukase
    • Organizer
      International Workshop of Biofunctional Chemistry for Young Scientists
    • Place of Presentation
      Awaji Yumebutai (Awaji)
    • Year and Date
      2009-07-22
    • Related Report
      2009 Annual Research Report
  • [Presentation] Isolation and Chemical Modification of Bangladeshi Medicinal Plants2009

    • Author(s)
      Kishor Mazumder, Eric, R.O.Siwu, Katsunori Tanaka, Koichi Fukase
    • Organizer
      International Workshop of Biofunctional Chemistry for Young Scientists
    • Place of Presentation
      Awaji Yumebutai (Awaji)
    • Year and Date
      2009-07-22
    • Related Report
      2009 Annual Research Report
  • [Presentation] IN VIVO IMAGING OF N-GLYCAN CLUSTERS BY FLU ORESCENCE- AND POSITRON EMISSION TOMOGRAPHY (PET)2009

    • Author(s)
      Eric R.O.Siwu, Kaori Minami, Koki Hasegawa, Satoshi Nozaki, Yousuke Kanayama, Yasuyoshi Watanabe, Koichi Koyama, Katsunori Tanaka, Koichi Fukase
    • Organizer
      15th European Carbohydrate Symposium
    • Place of Presentation
      Vienna,オーストリア
    • Year and Date
      2009-07-19
    • Related Report
      2009 Annual Research Report
  • [Presentation] マイクロフロー/バッチ混合系を用いたN-グリコシル化反応の開発とN-結合型糖鎖固相合成への応用2009

    • Author(s)
      宮川卓也、田中克典、深瀬浩一
    • Organizer
      第44回天然物化学談話会
    • Place of Presentation
      つくばグランドホテル(つくば)
    • Year and Date
      2009-07-08
    • Related Report
      2009 Annual Research Report
  • [Presentation] マイクロフロー反応を鍵とする生理活性天然物の実用的合成戦略2009

    • Author(s)
      田中克典
    • Organizer
      有機合成化学春季講習会,日本薬学会長井記念ホール
    • Place of Presentation
      東京
    • Year and Date
      2009-06-18
    • Related Report
      2010 Final Research Report
  • [Presentation] マイクロフロー反応を鍵とする生理活性天然物の実用的合成戦略2009

    • Author(s)
      田中克典
    • Organizer
      有機合成化学春季講習会
    • Place of Presentation
      日本薬学会・永井記念ホール(東京)
    • Year and Date
      2009-06-18
    • Related Report
      2009 Annual Research Report
  • [Presentation] アスパラギン結合型糖タンパク質糖鎖クラスターの蛍光およびPETイメージング2009

    • Author(s)
      Eric R.O.Siwu、南香莉、長谷川功紀、野崎聡、金山洋介、渡辺恭良、小山幸一、田中克典、深瀬浩一
    • Organizer
      日本ケミカルバイオロジー学会第4回年会
    • Place of Presentation
      神戸市産業振興センター(神戸)
    • Year and Date
      2009-05-19
    • Related Report
      2009 Annual Research Report
  • [Presentation] 高速6π-アザ電子環状反応を用いた細胞表層への化学的標識と糖鎖エンジニアリング:細胞のインビボイメージング2009

    • Author(s)
      南香莉、Eric R.O.Siwu、田原強、野崎聡、渡辺恭良、小山幸一、田中克典、深瀬浩一
    • Organizer
      日本ケミカルバイオロジー学会第4回年会
    • Place of Presentation
      神戸市産業振興センター(神戸)
    • Year and Date
      2009-05-19
    • Related Report
      2009 Annual Research Report
  • [Presentation] A New Strategy in Synthetic Biology : From Enzyme Inhibition, Natural Products Synthesis to PET Imaging by 6π-Azaelectrocyclizations2009

    • Author(s)
      田中克典
    • Organizer
      (株)キシダ化学
    • Place of Presentation
      キシダ化学(神戸三田)
    • Year and Date
      2009-04-22
    • Related Report
      2009 Annual Research Report
  • [Presentation] 超高速6π-アザ電子環状反応を用いた生体高分子標識化法の開発とPETイメージングへの応用2009

    • Author(s)
      田中克典
    • Organizer
      日本薬学会第129年会有機合成の若い力
    • Place of Presentation
      京都国際会議場
    • Year and Date
      2009-03-26
    • Related Report
      2010 Final Research Report
  • [Presentation] 超高速6π-アザ電子環状反応を用いた生体高分子標識化法の開発とPETイメージングへの応用2009

    • Author(s)
      田中克典
    • Organizer
      「有機合成化学の若い力」日本薬学会第129年会
    • Place of Presentation
      京都
    • Year and Date
      2009-03-26
    • Related Report
      2008 Annual Research Report
  • [Presentation] A New Strategy in Synthetic Biology : From Enzyme Inhibition, Natural Products Synthesis to PET Imaging by 6π-Azaelectrocyclizations2009

    • Author(s)
      田中克典
    • Organizer
      Departmental Seminar at Department of Chemistry,Host : Professor Babak Borhan
    • Place of Presentation
      Michigan State University
    • Year and Date
      2009-03-13
    • Related Report
      2010 Final Research Report
  • [Presentation] A New Strategy in Synthetic Biology: From Enzyme Inhibition, Natural Products Synthesis to PET Imaging by 6π-Azaelectrocyclizations2009

    • Author(s)
      田中克典
    • Organizer
      Departmental Seminar at Department of Chemistry, Host : Professor Hisashi Yamamoto
    • Place of Presentation
      The University of Chicago
    • Year and Date
      2009-03-13
    • Related Report
      2010 Final Research Report
  • [Presentation] A New Strategy in Synthetic Biology : From Enzyme Inhibition, Natural Products Synthesis to PET Imaging by 6π-Azaelectrocyclizations2009

    • Author(s)
      田中克典
    • Organizer
      Departmental Seminar at Department of Chemistry,Host : Professor Akira Kawamura
    • Place of Presentation
      CUNY-Hunter College
    • Year and Date
      2009-03-11
    • Related Report
      2010 Final Research Report
  • [Presentation] A New Strategy in Synthetic Biology : From Enzyme Inhibition, Natural Products Synthesis to PET Imaging by 6π-Azaelectrocyclizations2009

    • Author(s)
      田中克典
    • Organizer
      Departmental Seminar at Department of Chemistry,Host : Professor Richard P.Hsung
    • Place of Presentation
      University of Wisconsin at Madison
    • Year and Date
      2009-03-09
    • Related Report
      2010 Final Research Report
  • [Presentation] A New Strategy in Synthetic Biology : From Enzyme Inhibition, Natural Products Synthesis to PET Imaging by 6π-Azaelectrocyclizations2009

    • Author(s)
      田中克典
    • Organizer
      Departmental Seminar at Department of Chemistry,Host : Professor James W.Canary
    • Place of Presentation
      New York University (NYU)
    • Year and Date
      2009-03-06
    • Related Report
      2010 Final Research Report
  • [Presentation] 化合物ではなく"有機反応"を駆使したケミカルバイオロジー2009

    • Author(s)
      田中克典
    • Organizer
      理化学研究所,第8回ケミカルバイオロジー領域研究会Host:谷口直之教授
    • Place of Presentation
      和光
    • Year and Date
      2009-01-28
    • Related Report
      2010 Final Research Report
  • [Presentation] 生物製剤のインビボイメージングを指向した革新的標識法2009

    • Author(s)
      田中克典、南香莉、Eric R.O.Siwu、小山幸一、渡辺恭良、深瀬浩一
    • Organizer
      第28回メディシナルケミストリーシンポジウム
    • Place of Presentation
      東京大学(東京)
    • Related Report
      2009 Annual Research Report
  • [Presentation] タンパク質および細胞上での革新的化学反応を基盤とする糖鎖関連物質の非侵襲的イメージング2009

    • Author(s)
      田中克典、深瀬浩一
    • Organizer
      第7回糖鎖科学コンソーシアムシンポジウム
    • Place of Presentation
      千里ライフサイエンスセンター(大阪)
    • Related Report
      2009 Annual Research Report
  • [Presentation] Glycosylation in Microfluidic and on Solid Supports : Synthesis of Sialic Acid-Containing Complex-type N-Glycan2009

    • Author(s)
      Aiko Nakayabu, Yohei Fujii, Katsunori Tanaka, Koichi Fukase
    • Organizer
      The Eleventh International Kyoto Conference on New Aspects of Organic Chemistry (IKCOC-11)
    • Place of Presentation
      Kyoto Royal Hotel (Kyoto)
    • Related Report
      2009 Annual Research Report
  • [Presentation] Electrocyclization Chemistry on Protein and Surface of Cel l : Application to In Vivo Imaging2009

    • Author(s)
      Katsunori Tanaka, Kaori Minami, Koichi Fukase
    • Organizer
      The Eleventh International Kyoto Conference on New Aspects of Organic Chemistry (IKCOC-11)
    • Place of Presentation
      Kyoto Royal Hotel (Kyoto)
    • Related Report
      2009 Annual Research Report
  • [Presentation] Synthesis of Glycans by Integration of Solid-phase and Microfluidic Methods2009

    • Author(s)
      Koichi Fukase, Katsunori Tanaka, Yohei Fujii, Yasutaka Mori, Shin-ichi Tanaka, Guang-ming Bao, Eric R.O.Siwu, Yosuke Uchinasjii, Aiko Nakayabu, Takuya Miyagawa
    • Organizer
      5^<th> Spanish- Portuguese-Japanese Organic Chemistry Symposium
    • Place of Presentation
      Osaka Univ. (Osaka)
    • Related Report
      2009 Annual Research Report
  • [Presentation] Investigation of a-Sialylation Reactivity under Batch vs Various Microfluidic Conditions2009

    • Author(s)
      Yosuke Uchinashi, Katsunon Tanaka, Koichi Fukase
    • Organizer
      5^<th> Spanish- Portuguese-Japanese Organic Chemistry Symposium
    • Place of Presentation
      Osaka Univ. (Osaka)
    • Related Report
      2009 Annual Research Report
  • [Presentation] Synthesis of sialic acid-containing complex-type N-glycan on solid-supports2009

    • Author(s)
      Guang-ming Bao, Yohei Fujii, Hiroomi Tokimoto, Yasutaka Mori, Shin-ichi Tanaka, Katsunori Tanaka, and Koichi Fukase
    • Organizer
      Consortium for Functional Glycomics(HGPI)
    • Place of Presentation
      三重
    • Related Report
      2008 Annual Research Report
  • [Presentation] 高速電子環状反応を基盤としたN-結合型糖タンパク質糖鎖クラスターのPETイメージング2009

    • Author(s)
      Ehc R.O.Siwu・南香莉・長谷川功紀・金山洋介・小山幸一・渡辺恭良・田中克典・深瀬浩一
    • Organizer
      日本化学会第89春季年会
    • Place of Presentation
      東京
    • Related Report
      2008 Annual Research Report
  • [Presentation] 高速6p-アザ電子環状反応を用いたダンパク質および細胞表層への化学的糖鎖エンジニアリング2009

    • Author(s)
      南香莉・Eric R.O. Siwu・田原強・野崎聡・渡辺恭良・田中克典・深瀬浩一
    • Organizer
      日本化学会第89春季年会
    • Place of Presentation
      東京
    • Related Report
      2008 Annual Research Report
  • [Presentation] 化学的細胞エンジニアリングによるインビボ蛍光イメージング2009

    • Author(s)
      田中克典・南香莉・小山幸一・Eric R.O.Siwu・田原強・野崎聡・渡辺恭良・深瀬浩一
    • Organizer
      日本化学会第89春季年会
    • Place of Presentation
      東京
    • Related Report
      2008 Annual Research Report
  • [Presentation] 高運アザ電子環状反応を用いた生体高分子の革新的標識化法とPETイメージング2009

    • Author(s)
      田中克典・南香莉・Eric R.O.Siwu・小山幸一・長谷川功紀・田原強・水間広・和田康弘・渡辺恭良・深瀬浩一
    • Organizer
      日本化学会第89春季年会
    • Place of Presentation
      東京
    • Related Report
      2008 Annual Research Report
  • [Presentation] 化合物ではなく"有機反応"を駆使したケミカルバイオロジーの新戦略2008

    • Author(s)
      田中克典
    • Organizer
      平成20年度「戦略的大学連携支援事業」先端科学セミナー京都ケミカルバイオロジーシンポジウム,Host:椿一典教授平成20年度「戦略的大学連携支援事業」先端科学セミナー京都ケミカルバイオロジーシンポジウム,Host:椿一典教授
    • Place of Presentation
      京都府立大学,京都
    • Year and Date
      2008-12-15
    • Related Report
      2010 Final Research Report
  • [Presentation] "化合物"ではなく"有機反応"を駆使したケミカルバイオロジーの新戦略2008

    • Author(s)
      田中克典
    • Organizer
      平成20年度「戦略的大学連携支援事業」先端科学セミナー京都ケミカルバイオロジーシンポジウム
    • Place of Presentation
      京都
    • Year and Date
      2008-12-15
    • Related Report
      2008 Annual Research Report
  • [Presentation] 高速アザ電子環状反応を用いた生細胞表層の蛍光および糖鎖標識化法2008

    • Author(s)
      南香莉・藤井遥平・田原強・野崎聡・渡辺恭良・田中克典・深瀬浩一
    • Organizer
      平成20年度「戦略的大学連携支援事業」先端科学セミナー京都ケミカルバイオロジーシンポジウム
    • Place of Presentation
      京都
    • Year and Date
      2008-12-15
    • Related Report
      2008 Annual Research Report
  • [Presentation] 超高速電子環状反応を基盤としたPETイメージング : インビボ糖鎖関連物質ダイナミクス2008

    • Author(s)
      Eric, R.O.Siwu・長谷川功紀・金山洋介・渡辺恭良・田中克典・深瀬浩一
    • Organizer
      平成20年度「戦略的大学連携支援事業」先端科学セミナー京都ケミカルバイオロジーシンポジウム
    • Place of Presentation
      京都
    • Year and Date
      2008-12-15
    • Related Report
      2008 Annual Research Report
  • [Presentation] A New Strategy in Synthetic Biology : From Enzyme Inhibition, Natural Products Synthesis to PET Imaging by 6π-Azaelectrocyclizations2008

    • Author(s)
      田中克典
    • Organizer
      Departmental Seminar at Department of Chemistry,Host : Professor Jeffrey Bode
    • Place of Presentation
      University of Pennsylvania
    • Year and Date
      2008-11-18
    • Related Report
      2010 Final Research Report
  • [Presentation] A New Strategy in Synthetic Biology : From Enzyme Inhibition, Natural Products Synthesis to PET Imaging by 6π-Azaelectrocyclizations2008

    • Author(s)
      田中克典
    • Organizer
      Departmental Seminar at Department of Chemistry,Host : Professor Koji Nakanishi and Professor Nina Berova
    • Place of Presentation
      Columbia University
    • Year and Date
      2008-11-17
    • Related Report
      2010 Final Research Report
  • [Presentation] First Positron Emission Tomography(PET)Imaging of Glycoproteins and Glycodendrimers by Efficient Chemical Labeling with [^<68>Ga]-DOTA2008

    • Author(s)
      Katsunori Tanaka, Eric R. O. Siwu, Kaori Minami, Koki Hasegawa, Yosuke Kaneyama, Hiroshi Mizurna, Yasuhiro Wada, Yasuyoshi Watanabe, and Koichi Fukase
    • Organizer
      2008 Annual Meeting of the Society for Glycobiology
    • Place of Presentation
      Fort Worth
    • Year and Date
      2008-11-14
    • Related Report
      2008 Annual Research Report
  • [Presentation] First Positron Emission Tomography(PET)Imaging of Glycoproteins and Glycod endrimers by Efficient Chemical Labeling with [^<68>Ga]-DOTA2008

    • Author(s)
      Katsunori Tanaka, Eric R. O. Siwu, Kaori Minami, Koki Hasegawa, Yosuke Kaneyama, Hiroshi Mizurna, Yasuhiro Wada, Yasuyoshi Watanabe, and Koichi Fukase
    • Organizer
      Consortium for Functional Glycomics(HGPI)
    • Place of Presentation
      Fort Worth
    • Year and Date
      2008-11-13
    • Related Report
      2008 Annual Research Report
  • [Presentation] A New Strategy in Synthetic Biology : From Enzyme Inhibition, Natural Products Synthesis to PET Imaging by 6π-Azaelectrocyclizations2008

    • Author(s)
      田中克典
    • Organizer
      Departmental Seminar at Department of Molecular&Medical Pharmacology, Host : Professor Hsian-Rong Tseng
    • Place of Presentation
      UCLA
    • Year and Date
      2008-11-10
    • Related Report
      2010 Final Research Report
  • [Presentation] 革新的電子環状反応による生体高分子の標識化とインビボイメージング2008

    • Author(s)
      田中克典
    • Organizer
      (財)サントリー生物有機科学研究所セミナー,Host:楠本正一所長
    • Year and Date
      2008-10-21
    • Related Report
      2010 Final Research Report
  • [Presentation] A New Strategy in Synthetic Biology : From Enzyme Inhibition, Natural Products Synthesis to PET Imaging by 6π-Azaelectrocyclizations2008

    • Author(s)
      田中克典
    • Organizer
      Departmental Seminar at Department of Organic Chemistry and Biochemistry, Laboratory for Stereoselective Catalysis and Biocatalysis, Rudjer Boskovic Institute,Host : Professor Vitomir Sunjic and Professor Marin Roje
    • Place of Presentation
      Croatia
    • Year and Date
      2008-09-16
    • Related Report
      2010 Final Research Report
  • [Presentation] A Submicrogram-Scale PET Imaging of Biomolecules : New Labeling of Lysinesvia 6p-Azaelectrocyclization2008

    • Author(s)
      Katsunori Tanaka, Kaori Tatsuro Masuyama, Koki Haegawa, Tsuyoshi Tahara, Hiroshi Mizuma, Yasuhiro Wada, Yasuyoshi Watanabe, and Koichi Fukase
    • Organizer
      World Molecular Imaging Congress
    • Place of Presentation
      Nice,France
    • Year and Date
      2008-09-13
    • Related Report
      2008 Annual Research Report
  • [Presentation] Solid-Phase Synthesis of N-Linked Glycans2008

    • Author(s)
      K. Tanaka, Y. Fujii, H. Tokimoto, Y. Mori, S. Tanaka, G. Bao, K. Fukase
    • Organizer
      XXIV International Carbohydrate Symposium
    • Place of Presentation
      Oslo
    • Year and Date
      2008-07-27
    • Related Report
      2008 Annual Research Report
  • [Presentation] 酵素阻害機構に学ぶアザ電子環状反応の開発と天然物合成および生体内イメージング2008

    • Author(s)
      田中克典
    • Organizer
      東京農工大学工学部セミナーHost:長澤和夫教授
    • Year and Date
      2008-07-18
    • Related Report
      2010 Final Research Report
  • [Presentation] 超高速化学標識法の開発を基盤とした糖タンパク質、糖鎖付加人工抗体、および糖鎖クラスターのPETイメージング2008

    • Author(s)
      田中克典・南香莉・Eric R. O. Siwu・長谷川功紀・水間広・野崎聡・和田康弘・渡辺恭良・深瀬浩一
    • Organizer
      第9回関西グライコサイエンスフォーラム
    • Place of Presentation
      大阪
    • Year and Date
      2008-05-17
    • Related Report
      2008 Annual Research Report
  • [Presentation] 高速アザ電子環状反応を用いたケミカルバイオロジー研究2008

    • Author(s)
      田中克典
    • Organizer
      早稲田大学理工学部セミナー,Host:中尾洋一教授
    • Year and Date
      2008-05-08
    • Related Report
      2010 Final Research Report
  • [Presentation] マイクロー反応を用いた新合成戦略2008

    • Author(s)
      田中克典
    • Organizer
      和歌山県工業技術センターセミナー,Host:森一研究員
    • Year and Date
      2008-02-08
    • Related Report
      2010 Final Research Report
  • [Presentation] A Subnanogram-Scale Protocol for Biomolecule-Based-PET Imaging via Rapid 6p-Azaelectrocyclization: First Visualization of Sialic Acid-Dependent Circulatory Residence of Glycoproteins2008

    • Author(s)
      Katsunori Taraka
    • Organizer
      Clobal COE
    • Place of Presentation
      Osaka
    • Year and Date
      2008-01-29
    • Related Report
      2007 Annual Research Report
  • [Presentation] 超高速アザ電子環状反応を用いた生体分子標識化法の開発とPETイメージングへの応用2008

    • Author(s)
      増山達郎
    • Organizer
      生命化学研究会シンポジウム
    • Place of Presentation
      熊本
    • Year and Date
      2008-01-11
    • Related Report
      2007 Annual Research Report
  • [Presentation] ヒスチギン誘導体によるMeldal-Sharplessクリック反応の活性化;自己活性化クリックベブチドのダイナミックコンビナトリア合成2008

    • Author(s)
      景山知佳
    • Organizer
      生命化学研究会シンポジウム
    • Place of Presentation
      熊本
    • Year and Date
      2008-01-11
    • Related Report
      2007 Annual Research Report
  • [Presentation] APPLICATION OF RAPID 6p-AZAELECTROCYCLIZATION TO MOLECULA R IMAGING OF BIOMOLECULES2008

    • Author(s)
      Katsunori Tanaka, Kaori Minami, Eris R. O. Siwu, Koki Hasegawa, Tsuyoshi Tahara, Hiroshi Mizuma, Satoshi Nozaki, Yasuhiro Wada, Yasuyoshi Watanabe, and Koichi Fukase
    • Organizer
      Frontiers in Chemistry and Interface with Biology and Physics
    • Place of Presentation
      Osaka
    • Related Report
      2008 Annual Research Report
  • [Presentation] SYNTHETIC STUDY ON N-LINKED GLYCAN LIBRARY ON SOLID-SUPPORTS2008

    • Author(s)
      Guang-ming Bao, Yohei Fujii, Hiroomi Tokimoto, Yasutaka Mori, Shin-ichi Tanaka, Katsunori Tanaka, and Koichi Fuikase
    • Organizer
      Frontiers in Chemistry and Interface with Biology and Physics
    • Place of Presentation
      Osaka
    • Related Report
      2008 Annual Research Report
  • [Presentation] Solid-Phase Synthesis of N-Linked Glycans2008

    • Author(s)
      Katsunori Tanaka, Yohei Fujii, Hiroomi Tokimoto, Yastitaka Mori, Shin-ichi Tanaka, Guang-ming Bao and Koichi Fukase
    • Organizer
      17th International Conference on Organic Synthesis(ICOS)
    • Place of Presentation
      太田, Korea
    • Related Report
      2008 Annual Research Report
  • [Presentation] Acceleration of Cu(I)-Mediated Huisgen 1,3-Dipolar Cycloaddition by Histidine Derivatives : Facile Synthesis of Glycodendrimers for PET Imaging2008

    • Author(s)
      Eric R. O. Siwu, Chika Kageyama, Sanae Shirotsuki, Kastunori Tanaka and Koichi Fukase
    • Organizer
      17th International Conference on Organic Synthesis(ICCS)
    • Place of Presentation
      太田,Korea
    • Related Report
      2008 Annual Research Report
  • [Presentation] 高速アザ電子環状反応を用いた生細胞表層の蛍光および糖鎖標識法2008

    • Author(s)
      南香莉・藤井遥平・田原強・野崎聡・渡辺恭良・田中克典・深瀬浩一
    • Organizer
      第43回天然物化学談話会
    • Place of Presentation
      大阪
    • Related Report
      2008 Annual Research Report
  • [Presentation] ひょっとすると世の中の役に立つかも知れない、かなりの大量スケールでの天然物合成を目指して2008

    • Author(s)
      田中克典、難波康有祐
    • Organizer
      第43回天然物化学談話会
    • Place of Presentation
      大阪
    • Related Report
      2008 Annual Research Report
  • [Presentation] N-結合型糖タンパク質糖鎖の固相ライブラリー合成研究2008

    • Author(s)
      由中克典, Bao Guang-ming, 藤井遥平, 時本博臣, 森康貴, 田中伸一, 深瀬浩一
    • Organizer
      第28回日本糖質学会
    • Place of Presentation
      筑波
    • Related Report
      2008 Annual Research Report
  • [Presentation] 超高速化学標識法の開発を基盤とした糖タンパク質、糖鎖付加人工抗体、および糖鎖クラスターのPETイメージング2008

    • Author(s)
      田中克典、南香莉、Eric R. O. Siwu、長谷川功紀、野崎聡、水間広、和田康弘、渡辺恭良、深瀬浩一
    • Organizer
      FCCAグライコサイエンスフォーラム2008
    • Place of Presentation
      筑波
    • Related Report
      2008 Annual Research Report
  • [Presentation] シアル酸含有N-結合型糖タンパク質糖鎖の固相合成2008

    • Author(s)
      田中克典、中薮愛子、Eric R. O. Siwu、森康貴、Bao Guang-ming、深瀬浩一
    • Organizer
      FCCAグライコサイエンスフォーラム2008
    • Place of Presentation
      筑波
    • Related Report
      2008 Annual Research Report
  • [Presentation] Acceleration of Cu(I)-Mediated Huisgen 1,3-Dipolar Cycloaddition by Histidine Derivatives : Facile Synthesis of Glycodendrimers for PET Imaging2008

    • Author(s)
      Eric R. O. Siwu, Chika Kageyama, Sanae Shirotsuki, Kastunori Tanaka, and Koichi Fukase
    • Organizer
      The Fifth International Symposium on Integrated Synthe sis(ISIS-5)
    • Place of Presentation
      Kobe
    • Related Report
      2008 Annual Research Report
  • [Presentation] マイクロ経路内および固相上での効率的グリコシル化反応の開発を基盤としたN-結合型糖タンパク質糖鎖のライブラリー指向型合成研究2008

    • Author(s)
      田中克典, 藤井遥平, 時本博臣, 森康貴, 田中伸一, Guang-ming Bao, Eric R. O. Siwu,中薮愛子, 深瀬浩一
    • Organizer
      第50回天然有機化合物討論会
    • Place of Presentation
      福岡
    • Related Report
      2008 Annual Research Report
  • [Presentation] Synthesis of Biofunctional Molecules Using Microfluidic Systems2008

    • Author(s)
      Yasutaka Mori, Guang-ming Bao, Shin-ichi Tanaka, Yohei Fujii, Hiroomi Tokimoto, Shinya Motomatsu, Koichi Koyarna, Katsunori Tanaka, and Koichi Fukase
    • Organizer
      International Symposium on Micro Chemical Process and Synthesis
    • Place of Presentation
      Kyoto
    • Related Report
      2008 Annual Research Report
  • [Presentation] 生理活性物質のプロセス合成を意図したマイクロフロー反応の開発2008

    • Author(s)
      森康貴、田中伸一、元松信哉、小山幸一、田中克典、深瀬浩一
    • Organizer
      第27回メディシナルケミストリーシンポジウム
    • Place of Presentation
      大阪
    • Related Report
      2008 Annual Research Report
  • [Presentation] A Submicrogram-SCale Labeling of Biomolecules ria Rapid 6pai-Aza electrocyclization: Application to PET Imaging2008

    • Author(s)
      Katsunori Taraka
    • Organizer
      日本化学会 第87春季年会 Asian Symposium 20O8
    • Place of Presentation
      東京
    • Related Report
      2007 Annual Research Report
  • [Presentation] アゲ電子環状反応による細胞および微量タンパク質の超高速標識化とPErイメージング2008

    • Author(s)
      田中克典
    • Organizer
      日本化学会 第87春季年会
    • Place of Presentation
      東京
    • Related Report
      2007 Annual Research Report
  • [Presentation] ヒスチジン誘導体によるMeldal-Sharplessクリック羽か反応の活性化:自己活性化クリックペプチドのダイナミックコンビナトリア合成2008

    • Author(s)
      景山知佳
    • Organizer
      日本化学会 第87春季年会
    • Place of Presentation
      東京
    • Related Report
      2007 Annual Research Report
  • [Presentation] 複合型N-結合型糖タンパク質糖鎖固相合成2008

    • Author(s)
      藤井遥平
    • Organizer
      日本化学会 第87春季年会
    • Place of Presentation
      東京
    • Related Report
      2007 Annual Research Report
  • [Presentation] マイクロリアクターを用いた実用的なbeta-マンノシル化反応の開発2008

    • Author(s)
      森康貴
    • Organizer
      日本化学会 第87春季年会
    • Place of Presentation
      東京
    • Related Report
      2007 Annual Research Report
  • [Presentation] ライブフリー構築を指向した複合型N-結合型糖蛋白質糖鎖の固相合成2007

    • Author(s)
      藤井遥平
    • Organizer
      第27回有機合成若手セミナー
    • Place of Presentation
      京都
    • Year and Date
      2007-11-15
    • Related Report
      2007 Annual Research Report
  • [Presentation] A submicrogram-Scale Protocol for Biomolecule-Based PET Imaging Via Rapid 6π-Azaelectrocyclzation: First Visuzlization of Sialic. Acid-Dependent Circulatory Rsidence of Glycoproteins2007

    • Author(s)
      Katsunori Tanaka
    • Organizer
      Human Disease Glycomics/Proteome Initiative
    • Place of Presentation
      Lubeck
    • Year and Date
      2007-09-07
    • Related Report
      2007 Annual Research Report
  • [Presentation] Efficient Microfluidic a-Sialylation for the Synthesis of SialicAcid-Containing Oligosacchrides2007

    • Author(s)
      shin-ichi Tanaka
    • Organizer
      Human Disease Glycomics/Proteome Initiative
    • Place of Presentation
      Lubeck
    • Year and Date
      2007-09-07
    • Related Report
      2007 Annual Research Report
  • [Presentation] マイクロフローシステムを用いた生理活性物質の合成2007

    • Author(s)
      田中伸一
    • Organizer
      第34回有機反応懇談会
    • Place of Presentation
      大坂
    • Year and Date
      2007-07-27
    • Related Report
      2007 Annual Research Report
  • [Presentation] ヒスチジン誘導体によるSharpless クリック反応の活性化:自分活性化クリックペプチドのライブラリー構築2007

    • Author(s)
      景山知佳
    • Organizer
      第34回有機反応懇談会
    • Place of Presentation
      大坂
    • Year and Date
      2007-07-27
    • Related Report
      2007 Annual Research Report
  • [Presentation] 高速アザ電子環状反応によるジン残基選択的標識化法の関発:生体分子のpmo1スケールPETイメージング2007

    • Author(s)
      藤井遥平
    • Organizer
      第34回有機反応懇談会
    • Place of Presentation
      大坂
    • Year and Date
      2007-07-27
    • Related Report
      2007 Annual Research Report
  • [Presentation] 実用的なシアル酸含有糖鎖合成を目的とした高選択的a-シアリル化法の開発2007

    • Author(s)
      田中伸一
    • Organizer
      第8回関西グライコサイエンスフォーラム
    • Place of Presentation
      大坂
    • Year and Date
      2007-05-12
    • Related Report
      2007 Annual Research Report
  • [Presentation] マイクロフローシステムを用いた生理活性物質の合成2007

    • Author(s)
      田中克典
    • Organizer
      24th Conference on Combinatorial Chemistry, Japan
    • Place of Presentation
      大坂
    • Year and Date
      2007-04-24
    • Related Report
      2007 Annual Research Report
  • [Presentation] 超高速アザ電子環状反応を用いた生体分子標識化法の開発とPETイメージングへの応用2007

    • Author(s)
      田中克典
    • Organizer
      日本ケミカルバイオロジー研究会
    • Place of Presentation
      京都
    • Related Report
      2007 Annual Research Report
  • [Presentation] 高速アザ電子環状反応を用いた特定リジン残基のドミノ反応型蛍光標識法2007

    • Author(s)
      藤井遥平
    • Organizer
      第2回日本ケミカルバイオロジー研究会
    • Place of Presentation
      京都
    • Related Report
      2007 Annual Research Report
  • [Presentation] Synthesis of biofunctional molecules using microfluidic systems2007

    • Author(s)
      Katsunori Tanaka
    • Organizer
      Eurocobi4
    • Place of Presentation
      Firenze
    • Related Report
      2007 Annual Research Report
  • [Presentation] アザ電子環状反応を用いた超高速標識化法の関発:糖タンパク質のPETイメージング2007

    • Author(s)
      田中克典
    • Organizer
      第27回日本繕質学会年会
    • Place of Presentation
      福岡
    • Related Report
      2007 Annual Research Report
  • [Presentation] STUDIES TOWARD SOLID-PHASE SYNTHESIS OF N-LINKED GLYCAN LIBRARY2007

    • Author(s)
      Katsunori Tanaka
    • Organizer
      14th European Carhydrate Symposium
    • Place of Presentation
      Lubecd,
    • Related Report
      2007 Annual Research Report
  • [Presentation] EFFICIENT MICROFLUIDIC a-SIALYLATION FOR THE SYNTHSIS OF SIALIC ACID CONTAINING OLIGOSAHARIDES2007

    • Author(s)
      Shin-ichi Tanaka
    • Organizer
      14th European Carhydrate Symposium
    • Place of Presentation
      Lubeck
    • Related Report
      2007 Annual Research Report
  • [Presentation] Synthesis of Biofunctional Molecules Using Microfluidic Systems2007

    • Author(s)
      Katsunori Tanaka
    • Organizer
      The Fourth International Symposium on Integrated synthesis
    • Place of Presentation
      Hikone
    • Related Report
      2007 Annual Research Report
  • [Presentation] 超高速アザ電子環状反応を用いた生体分子標識化法の開罪とPETイメージング への応用2007

    • Author(s)
      田中克典
    • Organizer
      第22回生体機能関連化学シンポジウム
    • Place of Presentation
      仙台
    • Related Report
      2007 Annual Research Report
  • [Presentation] 高速アザ電子環状反応を用いた特定リジン残基のドミノ反応型蛍光標識化法2007

    • Author(s)
      藤井遥平
    • Organizer
      第22回生体機能関連化学シンポジウム
    • Place of Presentation
      仙台
    • Related Report
      2007 Annual Research Report
  • [Presentation] NEW LABELING METHOD OF BIOMOLECULES VIA RAPID AZAELECTROCYCLIZATION:APPLICATION TO PET IMAGING2007

    • Author(s)
      Katsunori Tanaka
    • Organizer
      第44回ペプチド討論会
    • Place of Presentation
      富山
    • Related Report
      2007 Annual Research Report
  • [Presentation] ACCELERATION OF Cu(I)-mEDIATED HUISGEN 1.3-DIPOLAR CYCLOADD ITON BY hISTIDINE DERIVATIVES: LIBRARY SYNTHESIS OF"SELF-ACTIVATING"CLICK PEPTIDES2007

    • Author(s)
      Chika Kageyama.
    • Organizer
      第44回ペプチド討論会
    • Place of Presentation
      富山
    • Related Report
      2007 Annual Research Report
  • [Presentation] A Submicrogram Scale Protocol for Biomlecule-eased PET Imaging via Rapid 6π-Azaelectrocyclization:First Visualization of Sialic Acid-Dependent Circulatory Residence of Glyoproteins2007

    • Author(s)
      Katsuncri Tanaka
    • Organizer
      The 4th takedu Science Foundation Symposium on PharmaSCience
    • Place of Presentation
      Tokyo
    • Related Report
      2007 Annual Research Report
  • [Presentation] SOLLD-PHASE SYNTHESIS OF N-LINKED CLYCANS AND FIRST PET IMAGING OF GLYCOPROTHINS2007

    • Author(s)
      Katsuncri Tanaka
    • Organizer
      International Symposium on Catalysis and Fine Chemicals 2007
    • Place of Presentation
      Singapore
    • Related Report
      2007 Annual Research Report
  • [Book] In R.Gerardy-Schahn, P.Delannoy, M.von Itzstein(eds)Topics in Current Chemistry volumes, SialoGlyco Chemistry and Biology2011

    • Author(s)
      K.Tanaka, K.Fukase
    • Publisher
      Chemical Approachto A Whole Body Imaging of Sialo-N-linked Glycans(未定,in press)
    • Related Report
      2010 Final Research Report
  • [Book] In P.Toy(ed)Solid-Phase Organic Synthesis Book. Wiley2011

    • Author(s)
      K.Tanaka, K.Fukase
    • Publisher
      Oligosaccharide Synthesis on Solid-supports(未定,in press)
    • Related Report
      2010 Final Research Report
  • [Book] In B.Fraser-Reid, K.Tatsuta, J.Thiem(eds)Glycoscience. Springer, Berlin2011

    • Author(s)
      K. Tanaka, Y.Fujimoto, S.Tanaka, Y.Mori, K.Fukase
    • Publisher
      Combinatorial Methods in Oligosaccharide Synthesis(未定,in press)
    • Related Report
      2010 Final Research Report
  • [Book] In B. Fraser-Reid, K. Tatsuta, J.Thiem(eds)Glycoscience. Springer, Berlin2011

    • Author(s)
      K.Tanaka, K.Fukase
    • Publisher
      Polymer-supported and Tag-assisted Methods in Oligosaccharide Synthesis(未定,in press)
    • Related Report
      2010 Final Research Report
  • [Book] 化学フロンティア2010:生命現象を理解する分子ツール最前線-イメージングから生体機能解析まで-化学2010

    • Author(s)
      田中克典, 深瀬浩一
    • Publisher
      株式会社 化学同人
    • Related Report
      2010 Annual Research Report
  • [Book] トランスレーショナルリサーチを支援する遺伝医学MOOK「創薬研究への分子イメージング応用」2010

    • Author(s)
      田中克典、深瀬浩一
    • Publisher
      メディカルドウ
    • Related Report
      2010 Annual Research Report
  • [Book] 『生体の科学』「糖鎖のかかわる病気」2010

    • Author(s)
      田中克典, 深瀬浩一
    • Publisher
      (財)金原一郎記念医学医療振興財団/医学書院(In press)
    • Related Report
      2009 Annual Research Report
  • [Book] Glycoscience : Chemistry and Chemical Biology I-III(2^<nd> ed., B.O.Fraser-Reid, K.Tatsuta, J.Thiem, eds., Polymer-supported and Tag-assisted Methods in Oligosaccharide Synthesis)2010

    • Author(s)
      Tanaka, K.; Fukase, K
    • Publisher
      Springer(In press)
    • Related Report
      2009 Annual Research Report
  • [Book] Glycoscience : Chemistry and Chemical Biology I-III(2^<nd> ed., B.O.Fraser-Reid, K.Tatsuta, J.Thiem, eds., Combinatorial Methods in Oligosaccharide Synthesis)2010

    • Author(s)
      Tanaka, K.; Fujimoto, Y.; Tanaka, S.; Mori, Y.; Fukase, K.
    • Publisher
      Springer(In press)
    • Related Report
      2009 Annual Research Report
  • [Book] 複合糖質の化学と最新応用技術(糖鎖のインビボバイオイメージング, 正田晋一郎, 稲津敏行監修)2009

    • Author(s)
      田中克典, 深瀬浩一
    • Publisher
      株式会社シーエムシー出版
    • Related Report
      2010 Final Research Report
  • [Book] 複合糖質の化学と最新応用技術, 糖鎖のインビボバイオイメージング2009

    • Author(s)
      Tanaka, K.; Fukase, K
    • Publisher
      シーエムシー出版
    • Related Report
      2009 Self-evaluation Report
  • [Book] 複合糖質の化学と最新応用技術2009

    • Author(s)
      田中克典, 深瀬浩一
    • Publisher
      シーエムシー出版
    • Related Report
      2009 Annual Research Report
  • [Book] 第三の生命鎖「糖鎖」を活用・制御するケミカルバイオロジー,月刊BIO INDUSTRY2009

    • Author(s)
      田中克典, 深瀬浩一
    • Publisher
      シーエムシー出版
    • Related Report
      2009 Annual Research Report
  • [Book] Experimental Glycoscience, Glycochemistry2008

    • Author(s)
      Fukase, K. ; Fujimoto, Y. ; Tanaka, K.
    • Total Pages
      6
    • Publisher
      Springer
    • Related Report
      2008 Annual Research Report
  • [Remarks] ホームページ等

    • Related Report
      2010 Final Research Report
  • [Remarks] 科学新聞(2010年6月4日)

    • Related Report
      2010 Final Research Report
  • [Remarks] 読売新聞(2010年5月日)

    • Related Report
      2010 Final Research Report
  • [Remarks] 読売新聞(HP)(2010年5月21日)

    • Related Report
      2010 Final Research Report
  • [Remarks] 神戸新聞(HP)(2010年5月20日)

    • Related Report
      2010 Final Research Report
  • [Remarks] 日経プレスリリース(HP)(2010年5月20日)

    • Related Report
      2010 Final Research Report
  • [Remarks] 朝日新聞(2010年5月18日)

    • Related Report
      2010 Final Research Report
  • [Remarks] 日経プレスリリース(HP)(2010年4月19日)

    • Related Report
      2010 Final Research Report
  • [Remarks] 化学工業日報(2009年6月22日)

    • Related Report
      2010 Final Research Report
  • [Remarks] (株)キシダ化学ホームページ(2008年4月1日)

    • Related Report
      2010 Final Research Report
  • [Remarks] 理化学研究所ホームページ(2008年4月1日)

    • Related Report
      2010 Final Research Report
  • [Remarks] 1.理化学研究所ホームページ(2008年4月1日)

    • URL

      http://www.cmis.riken.jp/

    • Related Report
      2010 Annual Research Report
  • [Remarks] 2.(株)キシダ化学ホームページ(2008年4月1日)

    • URL

      http://www.kishida.co.jp/

    • Related Report
      2010 Annual Research Report
  • [Remarks] 3.化学工業日報(2009年6月22日)

    • Related Report
      2010 Annual Research Report
  • [Remarks] 4.日経プレスリリース(HP)(2010年4月19日)

    • URL

      http://release.nikkei.co.jp/detail.cfm?relID=249393&lindID=4

    • Related Report
      2010 Annual Research Report
  • [Remarks] 5.朝日新聞(2010年5月18日)

    • Related Report
      2010 Annual Research Report
  • [Remarks] 6.日経プレスリリース(HP)(2010年5月20日)

    • URL

      http://release.nikkei.co.jp/detail.cfm?relID=251785&lindID=4

    • Related Report
      2010 Annual Research Report
  • [Remarks] 7.神戸新聞(HP)(2010年5月20日)

    • URL

      http://www.kobe-np.co.jp/news/shakai/0003003881.shtml

    • Related Report
      2010 Annual Research Report
  • [Remarks] 8.読売新聞(HP)(2010年5月21日)

    • URL

      http://osaka.yomiuri.co.jp/science/news/20100521-0Y08T00271.html

    • Related Report
      2010 Annual Research Report
  • [Remarks] 9.読売新聞(2010年5月21日)

    • Related Report
      2010 Annual Research Report
  • [Remarks] 10.科学新聞(2010年6月4日)

    • Related Report
      2010 Annual Research Report
  • [Remarks]

    • URL

      http://www.chem.sci.osaka-u.ac.jp/lab/fukase/

    • Related Report
      2009 Annual Research Report
  • [Patent(Industrial Property Rights)] リジンデンドリマー型糖鎖クラスターの製造法とその応用2009

    • Inventor(s)
      深瀬浩一、田中克典、渡辺恭良、小山幸一
    • Industrial Property Rights Holder
      国立大学法人大阪大学、独立行政法人理化学研究所、キシダ化学株式会社
    • Filing Date
      2009-03-27
    • Related Report
      2010 Final Research Report
  • [Patent(Industrial Property Rights)] 新規ヘキサトリエン-β-カルボニル化合物2008

    • Inventor(s)
      深瀬浩一、田中克典、渡辺恭良、長谷川功紀、田原強
    • Industrial Property Rights Holder
      国立大学法人大阪大学、独立行政法人理化学研究所
    • Filing Date
      2008-02-05
    • Related Report
      2010 Final Research Report
  • [Patent(Industrial Property Rights)] 新規ヘキサトリエン- -カルボニル化合物2008

    • Inventor(s)
      深瀬浩一、田中克典、渡辺恭良、長谷川功紀、田原強
    • Industrial Property Rights Holder
      国立大学法人大阪大学、独立行政法人理化学研究所
    • Filing Date
      2008-02-05
    • Related Report
      2009 Self-evaluation Report
  • [Patent(Industrial Property Rights)] 新規ヘキサトリエン-β-カルボニル化合物2008

    • Inventor(s)
      深瀬浩一, 田中克典, 渡辺恭良, 長谷川功紀, 田原強
    • Industrial Property Rights Holder
      国立大学法人大阪大学、独立行政法人理化学研究所
    • Filing Date
      2008-02-05
    • Related Report
      2007 Annual Research Report
    • Overseas

URL: 

Published: 2007-04-01   Modified: 2016-04-21  

Information User Guide FAQ News Terms of Use Attribution of KAKENHI

Powered by NII kakenhi