• Search Research Projects
  • Search Researchers
  • How to Use
  1. Back to previous page

Abdominal obesity measured by multiple sliced CT, plasma adiponectin and colorectal adenoma

Research Project

Project/Area Number 19689014
Research Category

Grant-in-Aid for Young Scientists (A)

Allocation TypeSingle-year Grants
Research Field Hygiene
Research InstitutionNational Cancer Center Research Institute and Research Center for Innovative Oncology, National Cancer Center Hospital East

Principal Investigator

SASAZUKI Shizuka  National Cancer Center Research Institute and Research Center for Innovative Oncology, National Cancer Center Hospital East, がん予防・検診研究センター 予防研究部, 室長 (50392337)

Project Period (FY) 2007 – 2009
Project Status Completed (Fiscal Year 2009)
Budget Amount *help
¥27,690,000 (Direct Cost: ¥21,300,000、Indirect Cost: ¥6,390,000)
Fiscal Year 2009: ¥11,570,000 (Direct Cost: ¥8,900,000、Indirect Cost: ¥2,670,000)
Fiscal Year 2008: ¥8,060,000 (Direct Cost: ¥6,200,000、Indirect Cost: ¥1,860,000)
Fiscal Year 2007: ¥8,060,000 (Direct Cost: ¥6,200,000、Indirect Cost: ¥1,860,000)
Keywords内臓脂肪 / 大腸腺腫 / アデイポネクチン / アディポネクチン / アデポネクチン
Research Abstract

Among 1,205 eligible subjects who underwent PET-CT for cancer screening in Tokyo, visceral fat volume was associated with the prevalence of colorectal adenoma independently of body mass index in both sexes. Plasma level of C-peptide and IGFBP-1 were associated with colorectal adenoma among men but not women. An inverse and positive association of adiponectin and leptin was observed with colorectal adenoma, respectively.

Report

(3 results)
  • 2009 Annual Research Report   Final Research Report ( PDF )
  • 2008 Annual Research Report
  • Research Products

    (12 results)

All 2009 2008 Other

All Journal Article (8 results) (of which Peer Reviewed: 4 results) Presentation (1 results) Remarks (3 results)

  • [Journal Article] Methionine synthase A2756G polymorphism interacts with alcohol and folate intake to influence the risk of colorectal adenoma.2009

    • Author(s)
      Yamaji T, Iwasaki M, Sasazuki S, Sakamoto H, Yoshida T, Tsugane S.
    • Journal Title

      Cancer Epidemiol Biomarkers Prev. 18

      Pages: 267-274

    • Related Report
      2009 Final Research Report
  • [Journal Article] Visceral fat volume and the prevalence of colorectal adenoma.2009

    • Author(s)
      Yamaji T, Iwasaki M, Sasazuki S, Kurahashi N, Mutoh M, Yamamoto S, Suzuki M, Moriyama N, Wakabayashi K, Tsugane S.
    • Journal Title

      Am J Epidemiol. 170

      Pages: 1502-1511

    • Related Report
      2009 Final Research Report
  • [Journal Article] Dietary isoflavone and the risk of colorectal adenoma: a case-control study in Japan.2009

    • Author(s)
      Akhter M, Iwasaki M, Yamaji T, Sasazuki S, Tsugane S.
    • Journal Title

      Br J Cancer 100

      Pages: 1812-1816

    • Related Report
      2009 Final Research Report
  • [Journal Article] Visceral fat volume and the prevalence of colorectal adenoma.2009

    • Author(s)
      Yamaji T, Iwasaki M, Sasazuki S, Kurahashi N, Mutoh M, Yamamoto S, Suzuki M, Moriyama N, Wakabayashi K, Tsugane S.
    • Journal Title

      Am J Epidemiol 170

      Pages: 1502-1511

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Dietary isoflavone and the risk of colorectal adenoma : a case-control study in Japan2009

    • Author(s)
      Akhter M, Iwasaki M, Yamaji T, Sasazuki S, Tsugane S.
    • Journal Title

      Br J Cancer 100

      Pages: 1812-1816

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Methionine synthase A2756G polymorphism interacts with alcohol and folate intake to influence the risk of colorectal adenoma.2009

    • Author(s)
      Yamaji T, Iwasaki M, Sasazuki S, Sakamoto H, Yoshida T, Tsugane S.
    • Journal Title

      Cancer Epidemiol Biomarkers Prev 18

      Pages: 267-274

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Development of an automated 3D segmentation program for volume quantification of body fat distribution using CT.2008

    • Author(s)
      Ohshima S, Yamamoto S, Yamaji T, Suzuki M, Mutoh M, Iwasaki M, Sasazuki S, Kotera K, Tsugane S, Muramatsu Y, Moriyama N.
    • Journal Title

      Nippon Hoshasen Gijutsu Gakkai Zasshi. 64

      Pages: 1177-1181

    • NAID

      110007068971

    • Related Report
      2009 Final Research Report
  • [Journal Article] Development of an automated 3D segmentation program for volume quantification of body fat distribution using CT.2008

    • Author(s)
      Ohshima S, Yamamoto S, Yamaji T, Suzuki M, Mutoh M, Iwasaki M, Sasazuki S, Kotera K, Tsugane S, Muramatsu Y, Moriyama N.
    • Journal Title

      Nippon Hoshasen Gijutsu Gakkai Zasshi 64

      Pages: 1177-1181

    • NAID

      110007068971

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Presentation] Methionine synthase A2756G多型と大腸腺腫との関連2009

    • Author(s)
      山地大樹、岩崎基、笹月静、坂本裕美、吉田輝彦、津金昌一郎
    • Organizer
      第68回日本癌学会学術総会
    • Place of Presentation
      神奈川県横浜市
    • Related Report
      2009 Final Research Report
  • [Remarks]

    • URL

      http://epi.ncc.go.jp/mstudy/

    • Related Report
      2009 Final Research Report
  • [Remarks]

    • URL

      http://epi.ncc.go.jp/jp/mstudy/colon/

    • Related Report
      2009 Annual Research Report
  • [Remarks]

    • URL

      http://www.ncc.go.jp/jp/kenshin/divisions/03prev/03prev05.html

    • Related Report
      2008 Annual Research Report

URL: 

Published: 2007-04-01   Modified: 2016-04-21  

Information User Guide FAQ News Terms of Use Attribution of KAKENHI

Powered by NII kakenhi