Establishment of inbred strains in zebrafish
Project/Area Number |
19700372
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Research Category |
Grant-in-Aid for Young Scientists (B)
|
Allocation Type | Single-year Grants |
Research Field |
Laboratory animal science
|
Research Institution | National Institute of Genetics |
Principal Investigator |
SHINYA Minori National Institute of Genetics, 系統生物研究センター, 助教 (00372946)
|
Project Period (FY) |
2007 – 2010
|
Project Status |
Completed (Fiscal Year 2010)
|
Budget Amount *help |
¥3,840,000 (Direct Cost: ¥3,300,000、Indirect Cost: ¥540,000)
Fiscal Year 2010: ¥650,000 (Direct Cost: ¥500,000、Indirect Cost: ¥150,000)
Fiscal Year 2009: ¥650,000 (Direct Cost: ¥500,000、Indirect Cost: ¥150,000)
Fiscal Year 2008: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Fiscal Year 2007: ¥1,500,000 (Direct Cost: ¥1,500,000)
|
Keywords | 育種 / 遺伝学 / ゼブラフィッシュ / 近交系 / 育種遺伝 |
Research Abstract |
Zebrafish is a small fresh water fish which is one of the excellent model animals, especially for the developmental biology. Yet, there is no inbred strain in zebrafish. Since the genetic homogeneity of inbred strain improves the precision of analyses, the lack of inbred strains is a big disadvantage for zebrafish. Here, I have tried to inbreed two zebrafish wild-type strains through full sib-pair mating. Though one strain was failed to be succeeded after 13^<th> generation, the other strain has reached to breeding larvae of 20^<th> generation, which fulfills the definition of inbred strains.
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Report
(6 results)
Research Products
(6 results)