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Computational evaluation of dialysis fluid flow in variously-designed dialyzers

Research Project

Project/Area Number 19700388
Research Category

Grant-in-Aid for Young Scientists (B)

Allocation TypeSingle-year Grants
Research Field Biomedical engineering/Biological material science
Research InstitutionWaseda University

Principal Investigator

YAMAMOTO Kenichiro  Waseda University, 高等研究所, 助教 (00434316)

Project Period (FY) 2007 – 2009
Project Status Completed (Fiscal Year 2009)
Budget Amount *help
¥3,770,000 (Direct Cost: ¥3,200,000、Indirect Cost: ¥570,000)
Fiscal Year 2009: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000)
Fiscal Year 2008: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2007: ¥1,300,000 (Direct Cost: ¥1,300,000)
Keywords中空糸型透析器 / 透析液流動 / ハウジング形状 / 医用化学工学 / 透析器 / 流動解析 / 物質移動解析
Research Abstract

The objective of the present study is to evaluate by computational analysis the effects of dialyzer jacket baffle structure, taper angle, and taper length on dialysis fluid flow. The baffle fully surrounding hollow-fiber bundle and taper structure are effective for uniformizing dialysis fluid flow. Optimum design of dialysis jacket structure is essential to optimizing dialysis fluid flow and to increasing dialyzer performance.

Report

(4 results)
  • 2009 Annual Research Report   Final Research Report ( PDF )
  • 2008 Annual Research Report
  • 2007 Annual Research Report
  • Research Products

    (24 results)

All 2009 2008 2007

All Journal Article (9 results) (of which Peer Reviewed: 4 results) Presentation (15 results)

  • [Journal Article] Computational evaluation of dialysis fluid flow in dialyzers with variously-designed jackets2009

    • Author(s)
      K Yamamoto, M Matsuda, A Hirano, N Takizawa, S Iwashima, T Yakushiji, M Fukuda, T Miyasaka, K Sakai
    • Journal Title

      Artif. Organs 33(6)

      Pages: 481-486

    • Related Report
      2009 Final Research Report
    • Peer Reviewed
  • [Journal Article] Flow uniformity in oxygenators with different outlet port design2009

    • Author(s)
      A Hirano, K Yamamoto, M Matsuda, M Inoue, S Nagao, K Kuwana, M Kamiya, K Sakai
    • Journal Title

      ASAIO Journal 55

      Pages: 209-212

    • Related Report
      2009 Final Research Report
    • Peer Reviewed
  • [Journal Article] Technical Characterization of Dialysis Fluid Flow of Newly-Developed Dialyzers Using Mass Transfer Correlation Equations2009

    • Author(s)
      S Kunikata, M Fukuda, K Yamamoto, Y Yagi, M Matsuda, K Sakai
    • Journal Title

      ASAIO Journal 55

      Pages: 231-235

    • Related Report
      2009 Final Research Report
    • Peer Reviewed
  • [Journal Article] Computational evaluation of dialysis fluid flow in dialyzers with variously-designed jackets2009

    • Author(s)
      K Yamamoto, M Matsuda, A Hirano, et al.
    • Journal Title

      Artificial Organs 33

      Pages: 481-486

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] 新型血液透析器における透析液側流動の無次元相関式による評価2008

    • Author(s)
      國方賢, 八木優, 松田雅人, 山本健一郎, 福田誠, 薬師寺大二, 宮坂武寛, 酒井清孝
    • Journal Title

      腎と透析別冊65ハイパフォーマンスメンブレン'08

      Pages: 47-50

    • Related Report
      2009 Final Research Report
  • [Journal Article] コンピュータシミュレーションによる透析器のハウジング形状が透析液流動に及ぼす影響の解析2008

    • Author(s)
      滝沢夏生, 山本健一郎, 松田雅人, 薬師寺大二, 福田誠, 宮坂武寛, 酒井清孝
    • Journal Title

      腎と透析別冊65ハイパフォーマンスメンブレン'08

      Pages: 42-46

    • Related Report
      2009 Final Research Report
  • [Journal Article] コンピュータシミュレーションによる透析器のハウジング形状が透析液流動に及ぼす影響の解析2008

    • Author(s)
      滝沢夏生, 山本健一郎, 松田雅人, 薬師寺大二, 福田誠, 宮坂武寛, 酒井清孝
    • Journal Title

      腎と透析別冊ハイパフォーマンスメンブレン'08 第65巻別冊

      Pages: 42-46

    • Related Report
      2008 Annual Research Report
  • [Journal Article] 新型透析器のパルスレスポンス法と局所圧力測定による透析液流動評価2007

    • Author(s)
      長谷川真衣、山本健一郎、酒井清孝、薬師寺大二、福田誠、宮坂武寛
    • Journal Title

      腎と透析別冊ハイパフォーマンスメンブレン'07

      Pages: 62-65

    • Related Report
      2007 Annual Research Report
  • [Journal Article] 重篤な腎不全の治療に使われる透析膜と透析器2007

    • Author(s)
      山本健一郎、酒井清孝
    • Journal Title

      化単と教育 55

      Pages: 346-347

    • Related Report
      2007 Annual Research Report
  • [Presentation] 透析液流動改善のためにテーパ部を改良した透析器の開発2009

    • Author(s)
      平野彩香、山本健一郎、松田雅人、小川武人、薬師寺大二、宮坂武寛、酒井清孝
    • Organizer
      第47回日本人工臓器学会大会
    • Place of Presentation
      新潟
    • Related Report
      2009 Final Research Report
  • [Presentation] 救急医療のための装置開発2009

    • Author(s)
      山本健一郎、堀之内達也、松田雅人、松田兼一、酒井清孝
    • Organizer
      第47回日本人工臓器学会大会
    • Place of Presentation
      新潟
    • Related Report
      2009 Final Research Report
  • [Presentation] 血液透析器における流動と物質移動のシミュレーション解析2009

    • Author(s)
      石渡祥、山本健一郎、松田雅人、小川武 人、薬師寺大二、宮坂武寛、酒井清孝
    • Organizer
      化学工学会第41回秋季大会
    • Place of Presentation
      広島
    • Related Report
      2009 Annual Research Report 2009 Final Research Report
  • [Presentation] 透析器形状が透析液流動と物質移動に及ぼす影響2009

    • Author(s)
      平野彩香、山本健一郎、松田雅人、小川 武人、薬師寺大二、宮坂武寛、酒井清 孝
    • Organizer
      化学工学会第41回秋季大会
    • Place of Presentation
      広島
    • Related Report
      2009 Annual Research Report 2009 Final Research Report
  • [Presentation] Dialysis fluid flow in a hollow-fiber dialyzer and its effects on dialysis performance2009

    • Author(s)
      A Hirano, K Yamamoto, M Matsuda, T Ogawa, T Yakushiji, T Miyasaka, K Sakai
    • Organizer
      World Congress 2009 - Medical Physics and Biomedical Engineering
    • Place of Presentation
      Munich, Germany
    • Related Report
      2009 Final Research Report
  • [Presentation] テーパ部を改良したモデル透析器の試作と透析液流動の可視化2009

    • Author(s)
      平野彩香, 山本健一郎, 松田雅人, 小川武人, 薬師寺大二, 宮坂武寛, 酒井清孝
    • Organizer
      化学工学会米沢大会2009(3支部合同大会)
    • Place of Presentation
      山形大学工学部(米沢市)
    • Related Report
      2009 Final Research Report
  • [Presentation] ANSYS-CFXを用いた中空糸型透析器内における透析液流動の評価2009

    • Author(s)
      石渡祥, 山本健一郎, 小川武人, 宮坂武寛, 酒井清孝
    • Organizer
      第54回(社)日本透析医学会学術集会・総会
    • Place of Presentation
      横浜
    • Related Report
      2009 Annual Research Report 2009 Final Research Report
  • [Presentation] 透析液流動の改善に効果的な透析器テーパ部の作製とその評価2009

    • Author(s)
      平野彩香, 松田雅人, 山本健一郎, 酒井清孝
    • Organizer
      日本医工学治療学会第25回学術大会
    • Place of Presentation
      大阪
    • Related Report
      2009 Final Research Report
  • [Presentation] Dialysls fluid flow in a hollow-fiber dialyzer and its effects on dialysis performence2009

    • Author(s)
      A Hirano, K Yamamoto, M Matsuda, et al.
    • Organizer
      World Congress 2009-Medical Physics and Biomedical Engineering
    • Place of Presentation
      Munich, Germany
    • Related Report
      2009 Annual Research Report
  • [Presentation] テーパ部を改良したモデル透析器の試作と透析液流動の可視化2009

    • Author(s)
      平野彩香, 山本健一郎, 松田雅人, ほか
    • Organizer
      化学工学会米沢大会2009
    • Place of Presentation
      山形
    • Related Report
      2009 Annual Research Report
  • [Presentation] 透析液流動の改善に効果的な透析器ーパ部の作製とその評価2009

    • Author(s)
      平野彩香, 松田雅人, 山本健一郎, 酒井清孝
    • Organizer
      日本医工学治療学会第25回学術大会
    • Place of Presentation
      大阪
    • Related Report
      2009 Annual Research Report
  • [Presentation] コンピュータシミュレーションによる透析器テーパ構造の至適設計2008

    • Author(s)
      山本健一郎他
    • Organizer
      第53回日本透析医学会学術集会・総会
    • Place of Presentation
      神戸
    • Year and Date
      2008-06-22
    • Related Report
      2008 Annual Research Report
  • [Presentation] 透析器ジャケットのテーパ形状が透析液流動に及ぼす影響2008

    • Author(s)
      山本健一郎他
    • Organizer
      日本医工学治療学会第24回学術大会
    • Place of Presentation
      幕張メッセ
    • Year and Date
      2008-04-19
    • Related Report
      2008 Annual Research Report
  • [Presentation] Effects of Taper Structure of Dialyzer Jacket on Dialysis Fluid Flow2008

    • Author(s)
      K. Yamamoto, et.al.
    • Organizer
      XXXV Annual meeting European Society for Artificial Organs (ESAO)
    • Place of Presentation
      Geneva, Switzerland
    • Related Report
      2008 Annual Research Report
  • [Presentation] Improved Housing of a New Dialyzer to Optimize Dialysate Flow2007

    • Author(s)
      K. Yamamoto et al.
    • Organizer
      ERA-EDTA XLIV Congress
    • Place of Presentation
      Barcelona, Spain
    • Related Report
      2007 Annual Research Report

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Published: 2007-04-01   Modified: 2016-04-21  

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