• Search Research Projects
  • Search Researchers
  • How to Use
  1. Back to previous page

Fabrication of functionalized poly (lactide) surfaces with the specific peptides

Research Project

Project/Area Number 19700400
Research Category

Grant-in-Aid for Young Scientists (B)

Allocation TypeSingle-year Grants
Research Field Biomedical engineering/Biological material science
Research InstitutionThe University of Tokyo

Principal Investigator

MATSUNO Hisao  The University of Tokyo, 駒場オープンラボラトリー, 助教 (50376696)

Project Period (FY) 2007 – 2008
Project Status Completed (Fiscal Year 2008)
Budget Amount *help
¥3,600,000 (Direct Cost: ¥3,300,000、Indirect Cost: ¥300,000)
Fiscal Year 2008: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2007: ¥2,300,000 (Direct Cost: ¥2,300,000)
Keywordsバイオコンジュゲイト / 生体適合性材料 / 生体機能材料 / 再生医工学材料 / 生体適合材料
Research Abstract

ポリ-L-乳酸(PLLA)結晶化表面に特異的に結合するペプチドのスクリーニングに成功した。PLLAに対する特異的な結合には、疎水性アミノ酸であるアラニンおよびロイシン残基、塩基性アミノ酸であるヒスチジンおよびアルギニン残基の寄与が特に大きいことを明らかにした。アミノ酸配列を同定したペプチドは、PLLA結晶らせん構造の微細な違いを識別できることを明らかにした。

Report

(3 results)
  • 2008 Annual Research Report   Final Research Report ( PDF )
  • 2007 Annual Research Report
  • Research Products

    (16 results)

All 2008 2007

All Journal Article (6 results) (of which Peer Reviewed: 4 results) Presentation (8 results) Book (2 results)

  • [Journal Article] Biological Selection of Peptides for Poly(L-lactide) Substrates2008

    • Author(s)
      Hisao Matsuno, Jun Sekine, Hirofumi Yajima, and Takeshi Serizawa
    • Journal Title

      Langmuir 24

      Pages: 6399-6403

    • Related Report
      2008 Final Research Report
  • [Journal Article] Biological Selection of Peptides for Poly(L-lactide)Substrates2008

    • Author(s)
      Hisao Matsuno
    • Journal Title

      Langmuir 24

      Pages: 6399-6403

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Journal Article] A Polymer Platform Composed of Structurally Well-defined Stereocomplex Structures for Efficient Enzymatic Reactions2008

    • Author(s)
      Hisao Matsuno
    • Journal Title

      Trans. MRS-J (印刷中)(掲載確定)

    • NAID

      130007809578

    • Related Report
      2007 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Protein Adsorption is Dependent on Substrate Polymer Polymorphs2007

    • Author(s)
      Hisao Matsuno, Yuya Nagasaka, Kimio Kurita, and Takeshi Serizawa
    • Journal Title

      Chem. Lett. 36

      Pages: 1238-1239

    • NAID

      10019961661

    • Related Report
      2008 Final Research Report
  • [Journal Article] Protein Adsorption is Dependent on Substrate Polymer Polymorphs2007

    • Author(s)
      Hisao Matsuno
    • Journal Title

      Chem. Lett. 36

      Pages: 1238-1239

    • NAID

      10019961661

    • Related Report
      2007 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Superior Activities of Enzymes Physically Immobilized on Structurally Regular Poly(methyl methacrylate)Surfaces.2007

    • Author(s)
      Hisao Matsuno
    • Journal Title

      Chem. Mater. 19

      Pages: 2174-2179

    • Related Report
      2007 Annual Research Report
    • Peer Reviewed
  • [Presentation] Isolation and Characterization of Peptides that Specifically Bind to Crystalline Poly (L-lactide)2008

    • Author(s)
      Hisao Matsuno
    • Organizer
      日韓高分子若手シンポジウム
    • Place of Presentation
      グリーピア津南
    • Year and Date
      2008-10-24
    • Related Report
      2008 Final Research Report
  • [Presentation] 短鎖ペプチドによるポリ乳酸ステレオコンプレックス表面認識2008

    • Author(s)
      松野寿生
    • Organizer
      第57回高分子学会年次大会
    • Place of Presentation
      パシフィコ横浜
    • Year and Date
      2008-05-28
    • Related Report
      2008 Final Research Report
  • [Presentation] 短鎖ペプチドによるポリ乳酸ステレオコンプレックス表面認識2008

    • Author(s)
      松野寿生
    • Organizer
      高分子学会年次大会
    • Place of Presentation
      パシフィコ横浜
    • Year and Date
      2008-05-28
    • Related Report
      2008 Annual Research Report
  • [Presentation] 短鎖ペプチドによるポリ乳酸結晶多形認識2008

    • Author(s)
      松野寿生
    • Organizer
      日本化学会第88春季年会
    • Place of Presentation
      立教大学
    • Year and Date
      2008-03-28
    • Related Report
      2008 Final Research Report
  • [Presentation] 構造制御されたポリ乳酸フィルムとタンパク質の相互作用2007

    • Author(s)
      松野寿生
    • Organizer
      第56回高分子討論会
    • Place of Presentation
      名古屋工業大学
    • Year and Date
      2007-09-19
    • Related Report
      2008 Final Research Report 2007 Annual Research Report
  • [Presentation] Novel design of the interface between functional proteins and polymer materials2007

    • Author(s)
      Hisao Matsuno
    • Organizer
      12^<th> IUOAC International Symposium on Macromolecular Complexes
    • Place of Presentation
      Fukuoka International congress center
    • Year and Date
      2007-08-30
    • Related Report
      2008 Final Research Report
  • [Presentation] Novel Design of The Interface Between Functional Proteins and Polymer Materials2007

    • Author(s)
      Hisao Matsuno
    • Organizer
      12th IUPAC International Syposium on Macromolecular Complexes
    • Place of Presentation
      Fukuoka International Congress Center
    • Year and Date
      2007-08-30
    • Related Report
      2007 Annual Research Report
  • [Presentation] 構造制御されたポリ乳酸フィルム特異的に結合するペプチドの探索2007

    • Author(s)
      松野寿生
    • Organizer
      第56回高分子学会年次大会
    • Place of Presentation
      京都国際会館
    • Year and Date
      2007-05-30
    • Related Report
      2008 Final Research Report
  • [Book] バイオナノプロセス溶液中でナノ構造を作るウェットテクノロジーの薦め第12章2008

    • Author(s)
      芹澤武・松野寿生
    • Publisher
      シーエムシー出版
    • Related Report
      2008 Final Research Report
  • [Book] バイオナノプロセス 溶液中でナノ構造を作るウェットテクノロジーの薦め 第12章2008

    • Author(s)
      芹澤 武
    • Publisher
      シーエムシー出版
    • Related Report
      2007 Annual Research Report

URL: 

Published: 2007-04-01   Modified: 2016-04-21  

Information User Guide FAQ News Terms of Use Attribution of KAKENHI

Powered by NII kakenhi