Preparation of Silyl Cation Species for Catalytic Asymmetric Synthesis
Project/Area Number |
19750069
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Research Category |
Grant-in-Aid for Young Scientists (B)
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Allocation Type | Single-year Grants |
Research Field |
Synthetic chemistry
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Research Institution | Hokkaido University |
Principal Investigator |
HARA Kenji Hokkaido University, 触媒化学研究センター, 准教授 (10333593)
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Project Period (FY) |
2007 – 2008
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Project Status |
Completed (Fiscal Year 2008)
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Budget Amount *help |
¥3,780,000 (Direct Cost: ¥3,300,000、Indirect Cost: ¥480,000)
Fiscal Year 2008: ¥2,080,000 (Direct Cost: ¥1,600,000、Indirect Cost: ¥480,000)
Fiscal Year 2007: ¥1,700,000 (Direct Cost: ¥1,700,000)
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Keywords | 触媒設計 / 反応 / ケイ素 / 触媒 / カチオン / 不斉 |
Research Abstract |
本研究課題は、強力なルイス酸としての機能を有しながらも未開発であるケイ素カチオン種に着目し、その機能を不斉合成反応触媒として充分に発揮させるための独自の設計を施す手法の開発を目的とした。基本骨格を用いた合成経路の検証、分子集積触媒反応場の構築、メソポーラスシリカ表面上でのケイ素種の精密修飾手法の精査により精密な分子設計に基づいた効率的かつ特異な立体選択性を発現するケイ素カチオン種触媒を創成するための基礎的手法が確立した。
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Report
(3 results)
Research Products
(37 results)
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[Journal Article] Self-Assembled Monolayers of Compact Phosphanes with Alkanethiolate Pendant Groups: Remarkable Reusability and Substrate Selectivity in Rh Catalysis2008
Author(s)
Hara, K., Akiyama, R., Takakusagi, S., Uosaki, K., Yoshino, T., Kagi, H. and Sawamura, M.
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Journal Title
Angew. Chem. Int. Ed. 47
Pages: 5627-5630
Related Report
Peer Reviewed
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[Journal Article] Hydrogenation of Hindered Ketones Catalyzed by a Silica-Supported Compact Phosphine System2008
Author(s)
Kawamorita, S., Hamasaka, G., Ohmiya, H., Hara, K., Fukuoka, A. and Sawamura, M.
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Journal Title
Org. Lett. 10
Pages: 4697-4700
Related Report
Peer Reviewed
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[Journal Article] Synthesis, Properties and Catalytic Applications of Caged, Compact Trialkylphosphine 4-Phenyl-1-phospha-4-silabicyclo[2.2.2]octane2008
Author(s)
Ochida, A., Hamasaka, G., Yamauchi, Y., Kawamorita, S., Ohshima, N., Hara, K., Ohmiya, H. and Sawamura, M.
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Journal Title
Organometallics 27
Pages: 5494-5503
Related Report
Peer Reviewed
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[Journal Article] Synthesis of Silica-Supported Compact Phosphines and Their Application to Rhodium-Catalyzed Hydrosilylation of Hindered Ketones with Triorganosilanes2008
Author(s)
Hamasaka, G., Kawamorita, S., Ochida, A., Akiyama, R., Hara, K., Fukuoka, A., Asakura, K., Chun, W. J., Ohmiya, H. and Sawamura, M.
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Journal Title
Organometallics 27
Pages: 6495-6506
Related Report
Peer Reviewed
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[Journal Article] Self-Assembled Monolayers of Compact Phosphanes with Alkanethiolate Pendant Groups: Remarkable Reusability and Substrate Selectivity in Rh Catalysis2008
Author(s)
Hara, K., Akiyama, R., Takakus agi, S., Uosaki, K., Yoshino, T.,Kagi, H. and Sawamura, M.
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Journal Title
Angew. Chem. Int. Ed 47
Pages: 5627-5630
Related Report
Peer Reviewed
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[Journal Article] Hydrogenation of Hindered Ketones Catalyzed by a Silica-Supported Co mpact Phosphine System2008
Author(s)
Kawamorita, S., Hamasaka, G., Ohmiya, H., Hara, K., Fukuoka, A. and Sawamura, M.
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Journal Title
Org. Lett 10
Pages: 4697-4700
Related Report
Peer Reviewed
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[Journal Article] Synthesis, Properties and Catalytic Applications of Caged, Compact Tria lkylphosphine 4-Phenyl-1-phospha-4-silabicyclo[2. 2. 2]octane2008
Author(s)
Ochida, A., Hamasaka, G., Yam auchi, Y., Kawamorita, S., Ohsh ima, N., Hara, K., Ohmiya, H. and Sawamura, M.
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Journal Title
Organometallics 27
Pages: 5494-5503
Related Report
Peer Reviewed
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[Journal Article] Synthesis of Silica-Supported Compact Phosphines and Their Application to Rhodium-Catalyzed Hydrosilylation of Hindered Ketones with Thor ganosilanes2008
Author(s)
Hamasaka, G., Kawamorita, S., Ochida, A., Akiyama, R., Hara, K., Fukuoka, A., Asakura, K., C hun, W. J., Ohmiya, H. and Sa wamura, M.
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Journal Title
Organometallics 27
Pages: 6495-6506
Related Report
Peer Reviewed
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[Presentation] Self-Assembled Monolayer of Alkanethiolate on Gold Surface -Application to Catalysis-2008
Author(s)
Hara, K., Akiyama, R., Takakusagi, S., Uosaki, K., Fukuoka, A., Sawamura, M.
Organizer
22nd Conference of the European Colloid and Interface Society
Place of Presentation
Crakow, Poland
Related Report
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[Presentation] Monolayer of Rhodium-Phosphine Complex on Gold Surface: Reusable and Chemo-Selective Catalyst for Dehydrogenative Alcohol Silylation2008
Author(s)
Hara, K., Akiyama, R., Takakusagi, S., Uosaki, K., Fukuoka, A., Sawamura, M.
Organizer
the International Symposium on Creation and Control of Advanced Selective Catalysis
Place of Presentation
Kyoto
Related Report
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[Presentation] Monolayer of Rhodium-Phosphine Complex on Gold Surface: Reusable and Chem o-Selective Catalyst for Dehydrogenative Alcohol Silylation2008
Author(s)
Hara, K., Akiyama, R., Takakusagi, S., Uosaki, K., Fukuoka, A., Sawam ura, M.
Organizer
the International Symposium on Creation and Control of Advanced Selective Catalysis
Place of Presentation
京都市
Related Report
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[Presentation] Self-Assembled Monolayer of Alkanethiolate on Gold Surface -Application to Catalysis-2008
Author(s)
Hara, K., Akiyama, R., Takakusagi, S., Uosaki, K., Fukuoka, A., Sawamura, M.
Organizer
22nd Conference of the European Colloid and Interface Society
Place of Presentation
ポーランド・クラクフ
Related Report
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