Nucleoid architecture related to RNA molecules
Project/Area Number |
19770145
|
Research Category |
Grant-in-Aid for Young Scientists (B)
|
Allocation Type | Single-year Grants |
Research Field |
Molecular biology
|
Research Institution | University of Tsukuba |
Principal Investigator |
OHNIWA Ryosuke University of Tsukuba, 大学院・人間総合科学研究科, 助教 (30447883)
|
Project Period (FY) |
2007 – 2009
|
Project Status |
Completed (Fiscal Year 2009)
|
Budget Amount *help |
¥3,900,000 (Direct Cost: ¥3,300,000、Indirect Cost: ¥600,000)
Fiscal Year 2009: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2008: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2007: ¥1,300,000 (Direct Cost: ¥1,300,000)
|
Keywords | 染色体構築 / 機能 / 分配 / 大腸菌 / 核様体 / 転写 / 原子間力顕微鏡 / 黄色ブドウ球菌 / 動態制御機構 / ゲノム / 核様体タンパク質 |
Research Abstract |
The genomic DNA in bacteria is packed into cells as nucleoid, which is composed of genomic DNA, RNAs and proteins. I focused on the regulatory mechanism of the nucleoid structure because its dynamics is closely related to the essential biological processes such as transcription, translation, replication etc. In the present study, I found i) nucleoid structures are sustained by nascent single stranded RNA, ii) the proteins involved in the nucleoid is highly varied in species-specific and environmental-specific manners.
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Report
(4 results)
Research Products
(36 results)