Heterocyclic amines content in Brazilian foods and development of questionnaire for assessing heterocyclic amine intake

• Project/Area Number: 19790415
• Research Category: Grant-in-Aid for Young Scientists (B)
• Allocation Type: Single-year Grants
• Research Field: Hygiene
• Research Institution: National Cancer Center Research Institute and Research Center for Innovative Oncology, National Cancer Center Hospital East
• Principal Investigator: IWASAKI Motoki National Cancer Center Research Institute and Research Center for Innovative Oncology, National Cancer Center Hospital East, 予防研究部, 室長 (60392338)
• Research Collaborator: KATAOKA Hiroyuki 就実大学, 薬学部生物薬学科, 教授 (80127555)
• Project Period (FY): 2007 – 2008
• Project Status: Completed (Fiscal Year 2008)
• Budget Amount: ¥3,720,000 (Direct Cost: ¥3,300,000、Indirect Cost: ¥420,000); Fiscal Year 2008: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000); Fiscal Year 2007: ¥1,900,000 (Direct Cost: ¥1,900,000)
• Keywords: ヘテロサイクリックアミン / 発がん物質 / がん / 日系移民 / 疫学

Research Abstract

ブラジル在住日系人のヘテロサイクリックアミン摂取量を把握するための質問票を開発し、加熱食品中のヘテロサイクリックアミン含有量データベースを作成するために、ブラジルでよく用いられる調理法を用いて肉・魚類を調理しヘテロサイクリックアミンの分析を行った。その結果、食材、調理法、焼き具合(3-4 段階)、マリネの有無、皮の有無などの条件別のデータベースが整備され、質問票により摂取量推定が可能となった。

Research Products

• [Journal Article] Development of a Quantitative Food Frequency Questionnaire for assessing food, nutrient, and heterocyclic aromatic amine intake in Japanese Brazilians for a colorectal adenoma case-control study (2009)
  • Author(s): Sharma S, Iwasaki M, Kunieda C, Cao X, Ishihara J, Hamada G, Miyajima NT, Tsugane S Le Marchand L
  • Journal Title: Int J Food Sci Nutr 20 Pages: 1-12
  • Peer Reviewed
• [Journal Article] Isoflavone, polymorphisms in estrogen receptor genes and breast cancer risk in case-control studies in Japanese, Japanese Brazilians, and non-Japanese Brazilians (2009)
  • Author(s): Iwasaki M, Hamada GS, Nishimoto IN, Netto MM, Motola J Jr, Laginha FM, Kasuga Y, Yokoyama S, Onuma H, Nishimura H, Kusama R, Kobayashi M, Ishihara J, Yamamoto S, Hanaoka T, Tsugane S
  • Journal Title: Cancer Sci (Epub ahead of print)
  • NAID: 10025145891
  • Peer Reviewed
• [Journal Article] Isoflavone, polymorphisms in estrogen receptor genes and breast cancer risk in case-control studies in Japanese, Japanese Brazilians and non-Japanese Brazilians. (2009)
  • Author(s): Iwasaki M, et al.
  • Journal Title: Cancer Sci. (Epub ahead of print)
  • NAID: 10025145891
  • Peer Reviewed
• [Journal Article] Development of a Quantitative Food Frequency Questionnaire for assessing food, nutrient, and heterocyclic aromatic amine intake in Japanese Brazilians for a colorectal adenoma case-control study. (2009)
  • Author(s): Sharma S, et al.
  • Journal Title: Int J Food Sci Nutr (In press)
  • Peer Reviewed
• [Journal Article] Dietary isoflavone intake and breast cancer risk in case-control studies in Japanese, Japanese Brazilians, and non-Japanese Brazilians (2008)
  • Author(s): Iwasaki M, Hamada GS, Nishimoto IN, Netto MM, Motola J Jr, Laginha FM, Kasuga Y, Yokoyama S, Onuma H, Nishimura H, Kusama R, Kobayashi M, Ishihara J, Yamamoto S, Hanaoka T, Tsugane S
  • Journal Title: Breast Cancer Res Treat (Epub ahead of print)
  • Peer Reviewed
• [Journal Article] Secular trends in cancer mortality among Japanese immigrants in the state of Sao Paulo, Brazil, 1979-2001 (2008)
  • Author(s): Iwasaki M, Mameri CP, Hamada GS, Tsugane S
  • Journal Title: Eur J Cancer Prev 17 Pages: 1-8
  • Peer Reviewed
• [Journal Article] Secular Trends in Cancer Mortality among Japanese Immigrants in the State of Sao Paulo, Brazil, 1979-2001. (2008)
  • Author(s): Iwasaki M, et al.
  • Journal Title: Eur J Cancer Prev 17(1) Pages: 1-8
  • Peer Reviewed
• [Journal Article] Dietary isoflavone intake and breast cancer risk in case-control studies in Japanese, Japanese Brazilians, and non-Japanese Brazilians. (2008)
  • Author(s): Iwasaki M, et al.
  • Journal Title: Breast Cancer Res Treat. (Epub ahead of print)
  • Peer Reviewed
• [Journal Article] Secular Trends in Cancer Mortality among Japanese Immigrants in the State of Sao Paulo,Brazil,1979-2001 (2008)
  • Author(s): Iwasaki M, et. al.
  • Journal Title: Eur J Cancer Prev 17(1) Pages: 1-8
  • Peer Reviewed
• [Presentation] Dietary isoflavone intake, polymorphisms in estrogen receptor genes and the risk of breast cancer in case-control studies in Japanese, Japanese Brazilians, and non-Japanese Brazilians (2008)
  • Author(s): Iwasaki M, Hamada GS, Nishimoto IN, Netto MM, Motola J Jr, Laginha FM, Kasuga Y, Yokoyama S, Onuma H, Nishimura H, Kusama R, Kobayashi M, Ishihara J, Yamamoto S, Hanaoka T, Tsugane S
  • Organizer: XVIII IEA World Congress of Epidemiology
  • Place of Presentation: Porto Alegre, Brazil
• [Presentation] Dietary isoflavone intake, polymorphisms in estrogen receptor genes and the risk of breast cancer in case-control studies in Japanese, Japanese Brazilians, and non-Japanese Brazilians (2008)
  • Author(s): Iwasaki M, et al.
  • Organizer: XVIII IEA World Congress of Epidemiology
  • Place of Presentation: Porto Alegre
• [Presentation] Development of a quantitative food frequency questionnaire (QFFQ) to assess food, nutrient and heterocyclic amine intake in Japanese Brazilians (2007)
  • Author(s): Sharma S Iwasaki M, Kunieda C, Cao X, Ishihara J, Hamada G, Miyajima NT, Tsugane S, Le Marchand L
  • Organizer: 7th International Food Data Conference-Food Composition and Biodiversity
  • Place of Presentation: Sao Paulo, Brazil
• [Presentation] Development of a quantitative food frequency questionnaire(QFFQ)to assess food,nutrient and heterocyclic amine intake in Japanese Brazilians (2007)
  • Author(s): Sharma S, et. al.
  • Organizer: 7th International Food Data Conference-Food Composition and Biodiversity
  • Place of Presentation: Sao Paulo,Brazil