The relation between transmission from mothers to their infants and biofilm in the major pathogen of human dental caries
| Project/Area Number |
19791566
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Single-year Grants |
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| Research Field |
Orthodontic/Pediatric dentistry
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| Research Institution | Tokyo Medical and Dental University |
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Principal Investigator |
MOTEGI Mizuho Tokyo Medical and Dental University, 大学院・医歯学総合研究科, 助教 (60422474)
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| Co-Investigator(Renkei-kenkyūsha) |
TAKAGI Yuzo 東京医科歯科大学, 大学院・医歯学総合研究科, 教授 (30124697)
SENPUKU Hidenobu 国立感染症研究所, 細菌第一部, 室長 (20250186)
YONEZAWA Hideo 杏林大学, 大学院・医学研究科, 助教 (60453528)
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| Project Period (FY) |
2007 – 2010
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| Project Status |
Completed (Fiscal Year 2010)
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| Budget Amount *help |
¥4,450,000 (Direct Cost: ¥3,700,000、Indirect Cost: ¥750,000)
Fiscal Year 2010: ¥520,000 (Direct Cost: ¥400,000、Indirect Cost: ¥120,000)
Fiscal Year 2009: ¥520,000 (Direct Cost: ¥400,000、Indirect Cost: ¥120,000)
Fiscal Year 2008: ¥2,210,000 (Direct Cost: ¥1,700,000、Indirect Cost: ¥510,000)
Fiscal Year 2007: ¥1,200,000 (Direct Cost: ¥1,200,000)
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| Keywords | Streptococcus mutans / う蝕 / バイオフィルム / 母子感染 / 細菌 / 齲蝕 / バイオフイルム |
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| Research Abstract |
Streptococcus mutans, the major pathogen responsible for dental caries in humans, is a biofilm-forming bacterium. In this study, SMU832 and 833 of S.mutans genes may be related to acquirement of S.mutans from rearers such as mother. Moreover, the genes may be associated with biofilm development.
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Report
(4 results)
Research Products
(14 results)
