Stratified epithelial development and cancer progression
| Project/Area Number |
19890118
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| Research Category |
Grant-in-Aid for Young Scientists (Start-up)
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| Allocation Type | Single-year Grants |
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| Research Field |
General medical chemistry
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| Research Institution | Tokyo Medical and Dental University |
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Principal Investigator |
MATSUI Takeshi Tokyo Medical and Dental University, 難治疾患研究所, 特任講師 (10452442)
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| Co-Investigator(Renkei-kenkyūsha) |
KIKUCHI Shojiro 京都府立医科大学, 消化器腫瘍制御外科学部門, 助教 (70381960)
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| Project Period (FY) |
2007 – 2008
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| Project Status |
Completed (Fiscal Year 2008)
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| Budget Amount *help |
¥3,075,000 (Direct Cost: ¥2,670,000、Indirect Cost: ¥405,000)
Fiscal Year 2008: ¥1,755,000 (Direct Cost: ¥1,350,000、Indirect Cost: ¥405,000)
Fiscal Year 2007: ¥1,320,000 (Direct Cost: ¥1,320,000)
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|---|
| Keywords | 皮膚 / 分化 / 癌 / 大腸癌 / 分泌蛋白質 / 上皮 / 重層扁平上皮組織 / 上皮組織 / ノックアウトマウス / 発現解析 |
|---|
| Research Abstract |
大腸癌細胞株・大腸癌組織におけるDermokineの発現解析を行い、分泌型が、発現している事を明らかにした。そこで、血清腫瘍マーカーとしての応用性へ向けて、分泌型に対する抗体を作成し、血清検査系を構築した。
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Report
(3 results)
Research Products
(18 results)
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[Journal Article] Deficiency of zonula occludens-1 causesembryonic lethal phenotype associated withdefected yolk sac angiogenesis and apoptosis of embryonic cells2008
Author(s)
Katsuno T, Umeda K, Matsui T, Hata M.,Tamura A., Itoh M, Takeuchi K, Fujimori T, Nabeshima YI, Noda T, Tsukita S, Tsukita S
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Journal Title
Mol. Biol. Cell 19
Pages: 2465-2475
Related Report
Peer Reviewed
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[Journal Article] Deficiency of ZO-1 Causes Embryonic Lethal Phenotype Associated with Defected Yolk Sac Angiogenesis and Apoptosis of Embryonic Cells2008
Author(s)
Katsuno T, Umeda K, Matsui T, Hata M, Tamura A, Itoh M, Takeuchi K, Fujimori T, Nabeshima YI, Noda T, Tsukita S, Tsukita S.
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Journal Title
Related Report
Peer Reviewed
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[Presentation] 新規分泌型サイトカインDermokineを用いた新しい早期大腸癌血清診断法の開発と臨床応用2008
Author(s)
菊池正二郎, 田儀知之, 松井毅, 喜住文枝, 井田曜子, 今井俊夫, 星佐知, 片山政彦, 中西芳正, 岡本和真, 落合登志哉, 國場幸均, 大辻英吾
Organizer
第67回日本癌学会学術総会
Place of Presentation
名古屋(名古屋国際会議場)
Year and Date
2008-10-29
Related Report
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