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Analysis of the genes associating with Basal Cell Nevus Syndrome

Research Project

Project/Area Number 19890155
Research Category

Grant-in-Aid for Young Scientists (Start-up)

Allocation TypeSingle-year Grants
Research Field Surgical dentistry
Research InstitutionKyushu University

Principal Investigator

OKA Shoji  Kyushu University, 大学病院, 医員 (10452773)

Project Period (FY) 2007 – 2008
Project Status Completed (Fiscal Year 2008)
Budget Amount *help
¥3,085,000 (Direct Cost: ¥2,680,000、Indirect Cost: ¥405,000)
Fiscal Year 2008: ¥1,755,000 (Direct Cost: ¥1,350,000、Indirect Cost: ¥405,000)
Fiscal Year 2007: ¥1,330,000 (Direct Cost: ¥1,330,000)
KeywordssiRNA / 遺伝子発現 / 上皮細胞
Research Abstract

基底細胞母斑症候群におけるPTCH1遺伝子以外の遺伝的原因として、Msx2遺伝子をターゲットとして、遺伝子欠損マウス、およびヒト由来上皮細胞、また実際の顎骨嚢胞病変を用いて解析を行った。これまでに行った解析結果により、Msx2遺伝子もまた基底細胞母斑症候群における責任遺伝子となる可能性が示唆された。

Report

(3 results)
  • 2008 Annual Research Report   Final Research Report ( PDF )
  • 2007 Annual Research Report
  • Research Products

    (3 results)

All 2008 2007

All Journal Article (3 results) (of which Peer Reviewed: 3 results)

  • [Journal Article] TGF-beta-mediated Dlx5 signaling plays a crucial role in osteo-chondroprogenitor cell lineage determination during mandible development2008

    • Author(s)
      Oka K, Oka S, et al.
    • Journal Title

      Developmantal Bioloby 321(2)

      Pages: 303-309

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Journal Article] TGF-beta-mediated Dlx5 signaling plays a crucial role in osteo-chondroprogenitor cell lineage determination during mandible development2008

    • Author(s)
      Oka K., Oka S., et. al.
    • Journal Title

      Developmantal Bioloby (In press)

    • Related Report
      2007 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Smad4 is required to regulate the fate of cranial neural crestcells2007

    • Author(s)
      Ko SO, Chung IH, Xu X., Oka S., Zhao H., Cho ES, Deng C., Chai Y.
    • Journal Title

      Developmental Biology 302(1)

      Pages: 435-447

    • Related Report
      2007 Annual Research Report
    • Peer Reviewed

URL: 

Published: 2007-04-01   Modified: 2016-04-21  

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