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Biosensors using mesoporous films

Research Project

Project/Area Number 19H02803
Research Category

Grant-in-Aid for Scientific Research (B)

Allocation TypeSingle-year Grants
Section一般
Review Section Basic Section 36010:Inorganic compounds and inorganic materials chemistry-related
Research InstitutionNational Institute for Materials Science

Principal Investigator

YAMAUCHI Yusuke  国立研究開発法人物質・材料研究機構, 国際ナノアーキテクトニクス研究拠点, MANA主任研究者 (10455272)

Project Period (FY) 2019-04-01 – 2022-03-31
Project Status Completed (Fiscal Year 2021)
Budget Amount *help
¥18,070,000 (Direct Cost: ¥13,900,000、Indirect Cost: ¥4,170,000)
Fiscal Year 2021: ¥2,990,000 (Direct Cost: ¥2,300,000、Indirect Cost: ¥690,000)
Fiscal Year 2020: ¥2,990,000 (Direct Cost: ¥2,300,000、Indirect Cost: ¥690,000)
Fiscal Year 2019: ¥12,090,000 (Direct Cost: ¥9,300,000、Indirect Cost: ¥2,790,000)
Keywords多孔体
Outline of Research at the Start

本研究では,ブロックコポリマーを水溶液中でミセル化し,目的とする金属の金属塩類を溶解させ,最後に金属イオンを還元させることで所望の金属骨格からなる多孔体を合成する.金属イオンとミセル表面との効果的な相互作用を促すように,ブロックコポリマーの親水部を予め設計しておくこともポイントである.最終的には,バイオセンサの小型化を目的としているがこれに限るものではなく,幅広く応用可能な機能性多孔体の創製を目的としている.

Outline of Final Research Achievements

In our recent study, we have realized the world's first high-quality nanoporous metal (metal nanoporous material) using amphipathic molecules such as surfactants and block copolymers. This material possesses a porous body with high electrical conductivity whose skeleton is formed only from metal and is expected to be applied to an electrochemical system different from the conventional nanoporous inorganic oxide system. In this research, we further expanded these concepts and promoted their development in glucose sensors. In addition to aiming to develop a glucose sensor, we also aimed to construct a new theory by making the best use of the characteristics of metal nanoporous materials and understanding the correlation between physical properties and nanostructures. Finally, we developed a flexible device.

Academic Significance and Societal Importance of the Research Achievements

近年,分子同士の相互作用による「自己組織化」現象は,高次構造制御されたナノ材料をボトムアップ的に合成する方法として注目されている.その中でも両親媒性分子などを利用し,ナノレベルで細孔構造制御された多孔性物質の合成が可能である.米国Mobil社が提案した鋳型法による酸化物等のメソ領域における空間形成は,世界的に1990年代から活発に研究がなされ,合成条件を変えることで,様々な形態(ナノ粒子,薄膜など),組成(遷移金属酸化物,炭素,高分子など)のメソ多孔体が報告されてきた.本研究で扱う金属系ナノ空間材料は,その中でも特にユニークな材料であり,学術的なインパクトが高いと思われる.

Report

(4 results)
  • 2021 Annual Research Report   Final Research Report ( PDF )
  • 2020 Annual Research Report
  • 2019 Annual Research Report
  • Research Products

    (15 results)

All 2022 2021 2020 2019

All Journal Article (15 results) (of which Int'l Joint Research: 15 results,  Peer Reviewed: 15 results,  Open Access: 1 results)

  • [Journal Article] κ-Carrageenan Gel Modified Mesoporous Gold Chronocoulometric Sensor for Ultrasensitive Detection of MicroRNA2022

    • Author(s)
      Salahuddin Bidita、Masud Mostafa Kamal、Aziz Shazed、Liu Chia-Hung、Amiralian Nasim、Ashok Aditya、Hossain S. M. Azad、Park Hyeongyu、Wahab Md Abdul、Amin Mohammed A.、Chari M. Adharvana、Rowan Alan E.、Yamauchi Yusuke、Hossain Md. Shahriar A.、Kaneti Yusuf Valentino
    • Journal Title

      Bulletin of the Chemical Society of Japan

      Volume: 95 Issue: 1 Pages: 198-207

    • DOI

      10.1246/bcsj.20210286

    • NAID

      130008159273

    • Related Report
      2021 Annual Research Report
    • Peer Reviewed / Int'l Joint Research
  • [Journal Article] Nanoarchitectured superparamagnetic iron oxide-doped mesoporous carbon nanozymes for glucose sensing2022

    • Author(s)
      Wahab Md A.、Hossain S M Azad、Masud Mostafa Kamal、Park Hyeongyu、Ashok Aditya、Mustapic Mislav、Kim Minjun、Patel Dipak、Shahbazi Mahboobeh、Hossain Md. Shahriar A.、Yamauchi Yusuke、Kaneti Yusuf Valentino
    • Journal Title

      Sensors and Actuators B: Chemical

      Volume: 366 Pages: 131980-131980

    • DOI

      10.1016/j.snb.2022.131980

    • Related Report
      2021 Annual Research Report
    • Peer Reviewed / Int'l Joint Research
  • [Journal Article] Performance enhancement strategies for surface plasmon resonance sensors in direct glucose detection using pristine and modified UiO-66: effects of morphology, immobilization technique, and signal amplification2022

    • Author(s)
      Gumilar Gilang、Henzie Joel、Yuliarto Brian、Patah Aep、Nugraha Nugraha、Iqbal Muhammad、Amin Mohammed A.、Hossain Md. Shariar A.、Yamauchi Yusuke、Kaneti Yusuf Valentino
    • Journal Title

      Journal of Materials Chemistry A

      Volume: 10 Issue: 12 Pages: 6662-6678

    • DOI

      10.1039/d1ta08741j

    • Related Report
      2021 Annual Research Report
    • Peer Reviewed / Int'l Joint Research
  • [Journal Article] Mesoporous TiO2-based architectures as promising sensing materials towards next-generation biosensing applications2021

    • Author(s)
      Amri Fauzan、Septiani Ni Luh Wulan、Rezki Muhammad、Iqbal Muhammad、Yamauchi Yusuke、Golberg Dmitri、Kaneti Yusuf Valentino、Yuliarto Brian
    • Journal Title

      Journal of Materials Chemistry B

      Volume: 9 Issue: 5 Pages: 1189-1207

    • DOI

      10.1039/d0tb02292f

    • Related Report
      2021 Annual Research Report
    • Peer Reviewed / Int'l Joint Research
  • [Journal Article] Extracellular Vesicle Nanoarchitectonics for Novel Drug Delivery Applications2021

    • Author(s)
      Sharma Shayna、Masud Mostafa Kamal、Kaneti Yusuf Valentino、Rewatkar Prarthana、Koradia Aayushi、Hossain Md. Shahriar A.、Yamauchi Yusuke、Popat Amirali、Salomon Carlos
    • Journal Title

      Small

      Volume: 17 Issue: 42 Pages: 2102220-2102220

    • DOI

      10.1002/smll.202102220

    • Related Report
      2021 Annual Research Report
    • Peer Reviewed / Int'l Joint Research
  • [Journal Article] Enantioselective SERS sensing of pseudoephedrine in blood plasma biomatrix by hierarchical mesoporous Au films coated with a homochiral MOF2021

    • Author(s)
      Guselnikova Olga、Lim Hyunsoo、Na Jongbeom、Eguchi Miharu、Kim Hyun-Jong、Elashnikov Roman、Postnikov Pavel、Svorcik Vaclav、Semyonov Oleg、Miliutina Elena、Lyutakov Oleksiy、Yamauchi Yusuke
    • Journal Title

      Biosensors and Bioelectronics

      Volume: 180 Pages: 113109-113109

    • DOI

      10.1016/j.bios.2021.113109

    • Related Report
      2020 Annual Research Report
    • Peer Reviewed / Int'l Joint Research
  • [Journal Article] Mesoporous Rh nanoparticles as efficient electrocatalysts for hydrogen evolution reaction2021

    • Author(s)
      Kim Jiyoung、Kani Kenya、Kim Jeonghun、Yeon Jeong Seok、Song Min-Kyu、Jiang Bo、Na Jongbeom、Yamauchi Yusuke、Park Ho Seok
    • Journal Title

      Journal of Industrial and Engineering Chemistry

      Volume: 96 Pages: 371-375

    • DOI

      10.1016/j.jiec.2021.02.003

    • Related Report
      2020 Annual Research Report
    • Peer Reviewed / Int'l Joint Research
  • [Journal Article] In Search of Excellence: Convex versus Concave Noble Metal Nanostructures for Electrocatalytic Applications2021

    • Author(s)
      Iqbal Muhammad、Bando Yoshio、Sun Ziqi、Wu Kevin C.‐W.、Rowan Alan E.、Na Jongbeom、Guan Bu Yuan、Yamauchi Yusuke
    • Journal Title

      Advanced Materials

      Volume: 33 Issue: 13 Pages: 2004554-2004554

    • DOI

      10.1002/adma.202004554

    • Related Report
      2020 Annual Research Report
    • Peer Reviewed / Int'l Joint Research
  • [Journal Article] Soft template-mediated coupling construction of sandwiched mesoporous PPy/Ag nanoplates for rapid and selective NH3 sensing2021

    • Author(s)
      Wei Facai、Zhong Yonghui、Luo Hao、Wu Yong、Fu Jianwei、He Qingguo、Cheng Jiangong、Na Jongbeom、Yamauchi Yusuke、Liu Shaohua
    • Journal Title

      Journal of Materials Chemistry A

      Volume: 9 Issue: 13 Pages: 8308-8316

    • DOI

      10.1039/d1ta01110c

    • Related Report
      2020 Annual Research Report
    • Peer Reviewed / Int'l Joint Research
  • [Journal Article] First electrochemical synthesis of mesoporous RhNi alloy films for an alkali-mediated hydrogen evolution reaction2021

    • Author(s)
      Kani Kenya、Lim Hyunsoo、Whitten Andrew E.、Wood Kathleen、Yago Anya J. E.、Hossain Md. Shahriar A.、Henzie Joel、Na Jongbeom、Yamauchi Yusuke
    • Journal Title

      Journal of Materials Chemistry A

      Volume: 9 Issue: 5 Pages: 2754-2763

    • DOI

      10.1039/d0ta09348c

    • Related Report
      2020 Annual Research Report
    • Peer Reviewed / Int'l Joint Research
  • [Journal Article] Designed Patterning of Mesoporous Metal Films Based on Electrochemical Micelle Assembly Combined with Lithographical Techniques2020

    • Author(s)
      Lim Hyunsoo、Kim Jeonghun、Kani Kenya、Masud Mostafa Kamal、Park Hyeongyu、Kim Minjun、Alsheri Saad M.、Ahamad Tansir、Alhokbany Norah、Na Jongbeom、Malgras Victor、Bando Yoshio、Yamauchi Yusuke
    • Journal Title

      Small

      Volume: 16 Issue: 12 Pages: 1902934-1902934

    • DOI

      10.1002/smll.201902934

    • Related Report
      2019 Annual Research Report
    • Peer Reviewed / Int'l Joint Research
  • [Journal Article] A mesoporous non-precious metal boride system: synthesis of mesoporous cobalt boride by strictly controlled chemical reduction2020

    • Author(s)
      Jiang Bo、Song Hui、Kang Yunqing、Wang Shengyao、Wang Qi、Zhou Xin、Kani Kenya、Guo Yanna、Ye Jinhua、Li Hexing、Sakka Yoshio、Henzie Joel、Yusuke Yamauchi
    • Journal Title

      Chemical Science

      Volume: 11 Issue: 3 Pages: 791-796

    • DOI

      10.1039/c9sc04498a

    • Related Report
      2019 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Mesoporous Metal-Metalloid Amorphous Alloys: The First Synthesis of Open 3D Mesoporous Ni‐B Amorphous Alloy Spheres via a Dual Chemical Reduction Method2020

    • Author(s)
      Kang Yunqing、Henzie Joel、Gu Huajun、Na Jongbeom、Fatehmulla Amanullah、Shamsan Belqes Saeed A.、Aldhafiri Abdullah M.、Farooq W. Aslam、Bando Yoshio、Asahi Toru、Jiang Bo、Li Hexing、Yamauchi Yusuke
    • Journal Title

      Small

      Volume: 16 Issue: 10 Pages: 1906707-1906707

    • DOI

      10.1002/smll.201906707

    • Related Report
      2019 Annual Research Report
    • Peer Reviewed / Int'l Joint Research
  • [Journal Article] Nanoarchitectured Metal Phosphates and Phosphonates: A New Material Horizon toward Emerging Applications2019

    • Author(s)
      Bhanja Piyali、Na Jongbeom、Jing Tang、Lin Jianjian、Wakihara Toru、Bhaumik Asim、Yamauchi Yusuke
    • Journal Title

      Chemistry of Materials

      Volume: 31 Issue: 15 Pages: 5343-5362

    • DOI

      10.1021/acs.chemmater.9b01742

    • Related Report
      2019 Annual Research Report
    • Peer Reviewed / Int'l Joint Research
  • [Journal Article] Ternary Palladium-Boron-Phosphorus Alloy Mesoporous Nanospheres for Highly Efficient Electrocatalysis2019

    • Author(s)
      Lv Hao、Xu Dongdong、Sun Lizhi、Henzie Joel、Suib Steven L.、Yamauchi Yusuke、Liu Ben
    • Journal Title

      ACS Nano

      Volume: 13 Issue: 10 Pages: 12052-12061

    • DOI

      10.1021/acsnano.9b06339

    • Related Report
      2019 Annual Research Report
    • Peer Reviewed / Int'l Joint Research

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Published: 2019-04-18   Modified: 2023-01-30  

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